255 results on '"Haberl, A"'
Search Results
2. Effect of In Vitro Digestion on Bioactive Peptides Related to Immune and Gut Health in Intact Cows Milk and Hydrolyzed Protein-Based Infant Formulas.
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Grigorean, Gabriela, Du, Xiaogu, Kuhfeld, Russell, Haberl, Elisabeth, and Lönnerdal, Bo
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bioactive peptides ,extensively hydrolyzed infant formulas (eHFs) ,gut health ,immune health ,infant formula ,intact protein formulas (iPFs) ,prebiotics ,synbiotics ,Infant Formula ,Humans ,Digestion ,Infant ,Peptides ,Animals ,Gastrointestinal Microbiome ,Milk ,Hydrolysis ,Infant ,Newborn ,Protein Hydrolysates ,Cattle ,Milk Proteins ,Chromatography ,Liquid ,Infant Nutritional Physiological Phenomena - Abstract
Background/Objectives: Human milk is the optimal source of nutrition and protection against infection for infants. If breastfeeding is not possible, standard and hydrolyzed infant formulas (IF) are an alternative. Extensively hydrolyzed IFs (eHFs) contain bioactive peptides, but their activities have rarely been evaluated. The aim of this study was to characterize and compare the bioactive peptide profiles of different eHFs and standard IFs before and after in vitro digestion. Methods: Two forms, liquid and powder, of intact protein formula (iPF) and eHF were subjected to in vitro gastrointestinal digestion, mimicking a young infants gut (age 0-4 months) and an older infants gut (>6 months). Bioactive peptides of in vitro digested and undigested formulas were analysed with Liquid Chromatography-Mass Spectrometry (LC-MS). Results: In all samples, a variety of peptides with potential bioactive properties were found. Immuno-regulatory peptides, followed by antimicrobial and antioxidative peptides were most frequent, as were peptides promoting wound healing, increasing mucin secretion, regulating cholesterol metabolism, and preventing bacterial infection. Peptides typically found in yoghurt and colostrum were identified in some formula samples. Conclusions: The high amounts of bioactive peptides with various properties in eHFs and iPFs indicate a possible contribution to infection protection, healthy gut microbiomes, and immunological development of infants. eHFs showed similar compositions of bioactive peptides to iPFs, with intermittently increased peptide variety and quantity.
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- 2024
3. New radio continuum study of the Large Magellanic Cloud Supernova Remnant N49
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Ghavam, M., Filipović, M. D., Alsaberi, R. Z. E., Barnes, L. A., Crawford, E. J., Haberl, F., Kavanagh, P. J., Maggi, P., Payne, J., Rowell, G. P., Sano, H., Sasaki, M., Rajabpour, N., Tothill, N. F. H., and Urošević, and D.
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Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Astrophysics of Galaxies - Abstract
We present new Australia Telescope Compact Array (ATCA) radio observations toward N49, one of the brightest extragalactic Supernova remnants (SNRs) located in the Large Magellanic Cloud. Our new and archival ATCA radio observations were analysed along with $Chandra$ X-ray data. These observations show a prominent `bullet' shaped feature beyond the southwestern boundary of the SNR. Both X-ray morphology and radio polarisation analysis support a physical connection of this feature to the SNR. The 'bullet' feature's apparent velocity is estimated at $\sim$1300 km s$^{-1}$, based on its distance ($\sim$10 pc) from the remnant's geometric centre and estimated age ($\sim$7600 yrs). we estimated the radio spectral index, $\alpha= -0.55 \pm 0.03$ which is typical of middle-age SNRs. Polarisation maps created for N49 show low to moderate levels of mean fractional polarisation estimated at 7$\pm$1% and 10$\pm$1% for 5.5 and 9 GHz, respectively. These values are noticeably larger than found in previous studies. Moreover, the mean value for the Faraday rotation of SNR N49 from combining CABB data is 212$\pm$65 rad m$^{-2}$ and the maximum value of RM is 591$\pm$103 rad m$^{-2}$., Comment: 16 pages, accepted for publication in Publications of the Astronomical Society of Australia
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- 2024
4. The TRAPUM Small Magellanic Cloud pulsar survey with MeerKAT -- II. Nine new radio timing solutions and glitches from young pulsars
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Carli, E., Antonopoulou, D., Burgay, M., Keith, M. J., Levin, L., Liu, Y., Stappers, B. W., Turner, J. D., Barr, E. D., Breton, R. P., Buchner, S., Kramer, M., Padmanabh, P. V., Possenti, A., Krishnan, V. Venkatraman, Venter, C., Becker, W., Maitra, C., Haberl, F., and Thongmeearkom, T.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
We report new radio timing solutions from a three-year observing campaign conducted with the MeerKAT and Murriyang telescopes for nine Small Magellanic Cloud pulsars, increasing the number of characterised rotation-powered extragalactic pulsars by 40 per cent. We can infer from our determined parameters that the pulsars are seemingly all isolated, that six are ordinary pulsars, and that three of the recent MeerKAT discoveries have a young characteristic age of under 100 kyr and have undergone a spin-up glitch. Two of the sources, PSRs J0040$-$7337 and J0048$-$7317, are energetic young pulsars with spin-down luminosities of the order of 10$^{36}$ erg s$^{-1}$. They both experienced a large glitch, with a change in frequency of about 30 $\mu$Hz, and a frequency derivative change of order $-10^{-14}$ Hz s$^{-1}$. These glitches, the inferred glitch rate, and the properties of these pulsars (including potentially high inter-glitch braking indices) suggest these neutron stars might be Vela-like repeating glitchers and should be closely monitored in the future. The position and energetics of PSR J0048$-$7317 confirm it is powering a new Pulsar Wind Nebula (PWN) detected as a radio continuum source; and similarly the association of PSR J0040$-$7337 with the PWN of Supernova Remnant (SNR) DEM S5 (for which we present a new Chandra image) is strengthened. Finally, PSR J0040$-$7335 is also contained within the same SNR but is a chance superposition. It has also been seen to glitch with a change of frequency of $10^{-2}$ $\mu$Hz. This work more than doubles the characterised population of SMC radio pulsars., Comment: 20 pages, 13 figures, accepted for publication in Monthly Notices of the Royal Astronomical Society
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- 2024
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5. Einstein Probe discovery of a super-soft outburst from CXOU J005245.0-722844: a rare BeWD binary in the Small Magellanic Cloud
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Marino, A., Yang, H., Zelati, F. Coti, Rea, N., Guillot, S., Jaisawal, G. K., Maitra, C., Haberl, F., Kuulkers, E., Yuan, W., Feng, H., Tao, L., Jin, C., Sun, H., Zhang, W., Chen, W., Heuvel, E. P. J. van den, Soria, R., Zhang, B., Weng, S. -S., Ji, L., Zhang, G. B., Pan, X., Lv, Z., Zhang, C., Ling, Z., Chen, Y., Jia, S., Liu, Y., Ness, J. -U., Cheng, H. Q., Li, D. Y., Gendreau, K. C., Ng, M., and Strohmayer, T. E.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
On May 27 2024, the Wide-field X-ray Telescope onboard the Einstein Probe (EP) mission detected enhanced X-ray emission from a new transient source in the Small Magellanic Cloud (SMC) during its commissioning phase. Prompt follow-up with the EP Follow-up X-ray Telescope, the Swift X-ray Telescope and Nicer have revealed a very soft, thermally emitting source (kT$\sim$0.1 keV at the outburst peak) with an X-ray luminosity of L$\sim$4$\times$10$^{38}$ erg s$^{-1}$, coincident with CXOU J005245.0-722844. This super-soft outburst faded very quickly in a week time. Several emission lines and absorption edges were present in the X-ray spectrum, such as the Oxygen (0.57 keV) and Neon (0.92 keV) He-like emission lines, and deep Nitrogen (0.67 keV) and Oxygen (0.87 keV) absorption edges. The X-ray emission resembles typical nova outbursts from an accreting white dwarf (WD) in a binary system, despite the X-ray source being historically associated with an O9-B0e massive star exhibiting a 17.55 days periodicity in the optical band. The discovery of this super-soft outburst nails down CXOU J005245.0-722844 as a BeWD X-ray binary: an elusive evolutionary stage where two main-sequence massive stars have undergone a common envelope phase and experienced at least two episodes of mass transfer. In addition, the very short duration of the outburst and the presence of Ne features hint at a rather massive, i.e., close to the Chandrasekhar limit, Ne-O WD in the system., Comment: 9 pages, 5 figures; submitted to ApJL
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- 2024
6. Robustness of Explainable Artificial Intelligence in Industrial Process Modelling
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Kantz, Benedikt, Staudinger, Clemens, Feilmayr, Christoph, Wachlmayr, Johannes, Haberl, Alexander, Schuster, Stefan, and Pernkopf, Franz
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Computer Science - Machine Learning - Abstract
eXplainable Artificial Intelligence (XAI) aims at providing understandable explanations of black box models. In this paper, we evaluate current XAI methods by scoring them based on ground truth simulations and sensitivity analysis. To this end, we used an Electric Arc Furnace (EAF) model to better understand the limits and robustness characteristics of XAI methods such as SHapley Additive exPlanations (SHAP), Local Interpretable Model-agnostic Explanations (LIME), as well as Averaged Local Effects (ALE) or Smooth Gradients (SG) in a highly topical setting. These XAI methods were applied to various types of black-box models and then scored based on their correctness compared to the ground-truth sensitivity of the data-generating processes using a novel scoring evaluation methodology over a range of simulated additive noise. The resulting evaluation shows that the capability of the Machine Learning (ML) models to capture the process accurately is, indeed, coupled with the correctness of the explainability of the underlying data-generating process. We furthermore show the differences between XAI methods in their ability to correctly predict the true sensitivity of the modeled industrial process., Comment: 11 pages, 3 figures, accepted at the ICML'24 Workshop ML4LMS; updated with improved results and fixed typos
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- 2024
7. NICER timing of the X-ray thermal isolated neutron star RX J0806.4--4123
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Posselt, B., Pavlov, G. G., Ho, W. C. G., and Haberl, F.
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Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
The X-ray thermal isolated neutron star (XTINS) RX J0806.4--4123 shows interesting multiwavelength properties that seemingly deviate from those of similar neutron stars. An accurate determination of the spin frequency change over time can assist in interpreting RX J0806.4-4123's properties in comparison to those of other XTINSs and the wider pulsar population. From 2019 to 2023 we carried out a tailored X-ray timing campaign of RX J0806.4-4123 with the NICER instrument. We used statistical properties of the Fourier coefficients and the $Z_K^2$ test for phase-connecting separate observations and finding a timing solution for the entire dataset. We also developed a simple and universal method for estimating the uncertainties of frequency $\nu$ and its derivative $\dot{\nu}$ from the empirical dependencies of $Z_K^2$ on trial values of these parameters, with account of all significant harmonics of the frequency. Applying this method, we determined a spin-down rate $\dot{\nu} = -7.3(1.2)\times 10^{-17}\,{\rm Hz\, s}^{-1}$. The resulting spin-down power $\dot{E}=2.6\times 10^{29}$ erg s$^{-1}$ is the lowest among the XTINSs, and it is a factor of 60 lower than the X-ray luminosity of this neutron star. RX J0806.4-4123 is also among the pulsars with the lowest measured $\dot{E}$ in general., Comment: accepted by ApJ; 16 pages of which 7 pages are Appendix, describing details of optimal planning phase-connected observations and estimating timing uncertainties using the Fourier coefficients and the $Z_K^2$ test; v2: a few surplus words removed in section A5
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- 2024
8. XMM-Newton and NuSTAR discovery of a likely IP candidate XMMU J173029.8-330920 in the Galactic Disk
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Mondal, Samaresh, Ponti, Gabriele, Filor, Luke, Bao, Tong, Haberl, Frank, Salcedo, Ciro, Campana, Sergio, Hailey, Charles J., Mori, Kaya, and Rea, Nanda
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
We aim at characterizing the population of low-luminosity X-ray sources in the Galactic plane by studying their X-ray spectra and periodic signals in the light curves. We are performing an X-ray survey of the Galactic disk using XMM-Newton, and the source XMMU J173029.8-330920 was serendipitously discovered in our campaign. We performed a follow-up observation of the source using our pre-approved NuSTAR target of opportunity time. We used various phenomenological models in xspec for the X-ray spectral modeling. We also computed the Lomb-Scargle periodogram to search for X-ray periodicity. A Monte Carlo method was used to simulate 1000 artificial light curves to estimate the significance of the detected period. We also searched for X-ray, optical, and infrared counterparts of the source in various catalogs. The spectral modeling indicates the presence of an intervening cloud with $N_{\rm H}\sim(1.5-2.3)\times10^{23}\ \rm cm^{-2}$ that partially absorbs the incoming X-ray photons. The X-ray spectra are best fit by a model representing emission from a collisionally ionized diffuse gas with plasma temperature $kT=26^{+11}_{-5}$ keV. Furthermore, an Fe $K_{\alpha}$ line at $6.47^{+0.13}_{-0.06}$ keV was detected with an equivalent width of the line of $312\pm104$ eV. We discovered a coherent pulsation with a period of $521.7\pm0.8$ s. The 3-10 keV pulsed fraction of the source is around $\sim$50-60\%. The hard X-ray emission with plasma temperature $kT=26^{+11}_{-5}$ keV, iron $K_{\alpha}$ emission at 6.4 keV and a periodic behavior of $521.7\pm0.8$ s suggest XMMU J173029.8-33092 to be an intermediate polar. We estimated the mass of the central white dwarf to be $0.94-1.4\ M_{\odot}$ by assuming a distance to the source of $\sim1.4-5$ kpc., Comment: 7 pages, 4 figures, accepted for publication in A&A
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- 2024
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9. Reproducibility in Machine Learning-based Research: Overview, Barriers and Drivers
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Semmelrock, Harald, Ross-Hellauer, Tony, Kopeinik, Simone, Theiler, Dieter, Haberl, Armin, Thalmann, Stefan, and Kowald, Dominik
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Computer Science - Software Engineering ,Computer Science - Information Retrieval ,Computer Science - Machine Learning - Abstract
Research in various fields is currently experiencing challenges regarding the reproducibility of results. This problem is also prevalent in machine learning (ML) research. The issue arises, for example, due to unpublished data and/or source code and the sensitivity of ML training conditions. Although different solutions have been proposed to address this issue, such as using ML platforms, the level of reproducibility in ML-driven research remains unsatisfactory. Therefore, in this article, we discuss the reproducibility of ML-driven research with three main aims: (i) identifying the barriers to reproducibility when applying ML in research as well as categorize the barriers to different types of reproducibility (description, code, data, and experiment reproducibility), (ii) discussing potential drivers such as tools, practices, and interventions that support ML reproducibility, as well as distinguish between technology-driven drivers, procedural drivers, and drivers related to awareness and education, and (iii) mapping the drivers to the barriers. With this work, we hope to provide insights and to contribute to the decision-making process regarding the adoption of different solutions to support ML reproducibility., Comment: Pre-print of submission for the AI Magazine - comments to this pre-print are very welcome
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- 2024
10. Menger and consonant sets in the Sacks model
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Haberl, Valentin, Szewczak, Piotr, and Zdomskyy, Lyubomyr
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Mathematics - Logic ,Mathematics - General Topology ,54D20, 03E35 - Abstract
Using an iterated Sacks forcing and topological games, we prove that the existence of a totally imperfect Menger set in the Cantor cube with cardinality continuum, is independent from ZFC. We also analyze structures of Hurewicz or consonant subsets of the Cantor cube in the Sacks model., Comment: 26 pages
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- 2024
11. Thermally emitting isolated neutron star candidates from the SRG/eROSITA All-Sky Survey
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Kurpas, J., Schwope, A. D., Pires, A. M., and Haberl, F.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
The SRG/eROSITA All-Sky Survey (eRASS) allows for the creation of a complete sample of X-ray dim isolated neutron stars (XDINSs), which will significantly facilitate the study of their population properties, evolution, and connection to other families of isolated neutron stars (INSs). In this work, we conduct a systematic search for XDINSs on the western Galactic hemisphere and discuss the resulting candidate sample. Consistently with the properties of the known XDINSs, we selected all eRASS sources possessing a soft X-ray spectral distribution and that are unlikely to be associated with optical or infrared sources. Our selection criteria allowed us to recover all known XDINSs and previously proposed candidates. In addition, we put forward 33 new candidate members for dedicated follow-up identification campaigns. We found the resulting candidate sample to be about 30-50% complete, mainly due to source confusion and the stringent cross-matching criteria adopted. The candidates of the sample presented here can be divided into two groups: 13 soft and 20 somewhat hard X-ray emitters. Interestingly, the thermal nature, spatial distribution, lack of known counterparts, and absence of significant flux variability of the candidates in the first group agree well with the properties of other confirmed thermally emitting INSs. For the candidates in the second group, the current observational data do not allow one to discern between rotation-powered or recycled pulsars, cataclysmic variables, or quiescent neutron stars in binary systems or even to rule out an extragalactic nature. On the basis of population synthesis and the estimated source completeness of the search, we expect that between one and three new XDINSs are among the already singled-out list of XDINS candidates - a long-sought increase in the proposed number of members of this elusive class of X-ray emitters., Comment: 12 pages, 9 figures, accepted for publication in A&A
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- 2024
12. New quasars behind the Magellanic Clouds. II. Spectroscopic confirmation of 136 near-infrared selected candidates
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Ivanov, Valentin D., Cioni, Maria-Rosa L., Dennefeld, Michel, de Grijs, Richard, Craig, Jessica E. M., van Loon, Jacco Th., Pennock, Clara, Maitra, Chandreyee, and Haberl, Frank
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Astrophysics - Astrophysics of Galaxies - Abstract
Quasi-stellar objects (QSOs) are a basis for an absolute reference system for astrometric studies. There is a need for creating such system behind nearby galaxies, to facilitate the measuring of the proper motions of these galaxies. However, the foreground contamination from the galaxies themselves is a problem for the QSO identification. We search for new QSOs behind both Magellanic Clouds, the Magellanic Bridge, and the Magellanic Stream. We identify QSO candidates with a combination of near-infrared colors and variability criteria from the public ESO Visual and Infrared Survey Telescope for Astronomy (VISTA) Magellanic Clouds (VMC) survey. We confirm their nature from broad emission lines with low-resolution optical spectroscopy. We confirmed the QSO nature of 136 objects. They are distributed as follows: 12 behind the LMC, 37 behind the SMC, 63 behind the Bridge, and 24 behind the Stream. The QSOs span a redshift range from z~0.1 to z~2.9. A comparison of our quasar selection with the Quaia quasar catalog, based on Gaia low-resolution spectra, yields a selection and confirmation success rate of 6-19%, depending on whether the quality of the photometry, the magnitude ranges and the colors are considered. Our candidate list is rather incomplete, but the objects in it are likely to be confirmed as quasars with ~90% probability. Finally, we report a list of 3609 objects across the entire VMC survey that match our color and variability selection criteria; only 1249 of them have Gaia counterparts. Our combined infrared color and variability criteria for QSO selection prove to be efficient - ~90% of the observed candidates are bona fide QSOs and allow to generate a list of new high-probability quasar candidates., Comment: 20 pages, 9 figures, 5 tables
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- 2024
13. Periodicity from X-ray sources within the inner Galactic disk
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Mondal, Samaresh, Ponti, Gabriele, Bao, Tong, Haberl, Frank, Campana, Sergio, Hailey, Charles J., Mandel, Shifra, Mereghetti, Sandro, Mori, Kaya, Morris, Mark R., Rea, Nanda, and Sidoli, Lara
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
For many years, it has been claimed that the Galactic ridge X-ray emission at the Galactic Center (GC) is truly diffuse in nature. However, with the advancement of modern X-ray satellites, it has been found that most of the diffuse emission is actually comprised of thousands of previously unresolved X-ray point sources. Further, many studies suggest that a vast majority of these X-ray point sources are magnetic cataclysmic variables (mCVs) and active binaries. One unambiguous way to identify these mCVs and other sources is by detecting their X-ray periodicity. Therefore, we systematically searched for periodic X-ray sources in the inner Galactic disk, including the GC region. We have used data from our ongoing XMM-Newton Heritage survey of the inner Galactic disk ($350^{\circ}\lesssim l\lesssim+7^{\circ}$ and $-1^{\circ}\lesssim b\lesssim +1^{\circ}$) plus the XMM-Newton archival observations of the GC. We computed the Lomb-Scargle periodogram of the light curves for the periodicity search. We fitted the energy spectra of the sources using a simple power-law model plus three Gaussians at 6.4, 6.7, and 6.9 keV for the iron $K$ emission complex. We detected periodicity in 26 sources. For 14 of them, this is the first discovery of periodicity. For the other 12 sources, we found periods similar to those already known, indicating no significant period evolution. We also searched for the Gaia counterparts of the periodic sources to estimate their distances using the Gaia parallax. We found a likely Gaia counterpart for seven sources. We have classified the sources into four categories based on the periodicity, hardness ratio, and the equivalent width of Fe $K$ line emission. Of the 14 sources where we detect the periodicity for the first time, four are likely to be intermediate polars, five are likely to be polars, two are neutron star X-ray binaries, and three are of unknown nature., Comment: 19 pages, 9 figures, accepted for publication in A&A
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- 2024
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14. Decompressive craniotomy in split-technique (DCST) for TBI in infants: introducing a new surgical technique to prevent long-term complications
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Sarikaya-Seiwert, Sevgi, Shabo, Ehab, Schievelkamp, Arndt-Hendrik, Born, Mark, Wispel, Christian, and Haberl, Hannes
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- 2024
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15. The first all-sky survey of star-forming galaxies with eROSITA: Scaling relations and a population of X-ray luminous starbursts
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Kyritsis, E., Zezas, A., Haberl, F., Weber, P., Basu-Zych, A., Vulic, N., Maitra, C., Hämmerich, S., Wilms, J., Sasaki, M., Hornschemeier, A., Ptak, A., Merloni, A., and Comparat, J.
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Astrophysics - Astrophysics of Galaxies ,Astrophysics - High Energy Astrophysical Phenomena - Abstract
We present a study of X-ray normal galaxies using data from the first all-sky scan of the eROSITA X-ray survey. eRASS1 provides the first unbiased X-ray census of normal galaxies allowing us to study the X-ray emission from XRBs and the hot ISM in the full range of stellar population parameters present in the local Universe. By combining the HECATE value-added galaxy catalogue with the eRASS1, we study the X-ray emission from normal galaxies as a function of their SFR, M$_{*}$, Metallicity, and stellar population age. After applying optical and mid-IR activity classification criteria, we constructed a sample of 18790 star-forming galaxies with measurements of their L$_{X}$. By stacking the X-ray data in SFR-M$_{*}$-distance bins we study the correlation between the average L$_{X}$ and stellar population parameters. We also present updated L$_{\rm{X}}$-SFR and L$_{\rm{X}}$/SFR-Metallicity scaling relations accounting for the scatter dependence on the SFR. We find that the integrated L$_{X}$ of the HEC-eR1 star-forming galaxies is significantly elevated with respect to that expected from the current scaling relations. The observed scatter is also significantly larger. This excess persists even when we measure the average L$_{X}$ of galaxies in SFR-M$_{*}$-distance and metallicity bins and it is stronger in lower SFRs. The excess is not the result of hot gas, LMXBs, background AGN, LLAGN (including TDEs), or stochastic sampling of the XRB XLF. We find that while the excess correlates with lower metallicity, its primary driver is the age of the stellar populations. Our analysis reveals a sub-population of X-ray luminous starbursts with high sSFRs, low metallicities, and young stellar populations. This population drives upwards the X-ray scaling relations for star-forming galaxies, and has important implications for understanding the population of XRBs in the local and high-z Universe., Comment: Submitted to A&A
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- 2024
16. The SRG/eROSITA all-sky survey: Cosmology constraints from cluster abundances in the western Galactic hemisphere
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Ghirardini, V., Bulbul, E., Artis, E., Clerc, N., Garrel, C., Grandis, S., Kluge, M., Liu, A., Bahar, Y. E., Balzer, F., Chiu, I., Comparat, J., Gruen, D., Kleinebreil, F., Krippendorf, S., Merloni, A., Nandra, K., Okabe, N., Pacaud, F., Predehl, P., Ramos-Ceja, M. E., Reiprich, T. H., Sanders, J. S., Schrabback, T., Seppi, R., Zelmer, S., Zhang, X., Bornemann, W., Brunner, H., Burwitz, V., Coutinho, D., Dennerl, K., Freyberg, M., Friedrich, S., Gaida, R., Gueguen, A., Haberl, F., Kink, W., Lamer, G., Li, X., Liu, T., Maitra, C., Meidinger, N., Mueller, S., Miyatake, H., Miyazaki, S., Robrade, J., Schwope, A., and Stewart, I.
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Astrophysics - Cosmology and Nongalactic Astrophysics ,General Relativity and Quantum Cosmology - Abstract
The cluster mass function traces the growth of linear density perturbations and provides valuable insights into the growth of structures, the nature of dark matter, and the cosmological parameters governing the Universe. The primary science goal of eROSITA, on board the {\it Spectrum Roentgen Gamma (SRG)} mission, launched in 2019, is to constrain cosmology through the evolution of cluster mass function. In this paper, we present the cosmological constraints obtained from 5259 clusters of galaxies detected over an area of 12791~deg$^2$ in the Western Galactic Hemisphere of the eROSITA's first All-Sky Survey (eRASS1). The common footprint region between the eROSITA Survey and DES, KiDS, and HSC surveys is used for calibration of the scaling between X-ray count rate and their total mass through measurements of their weak gravitational lensing signal. eRASS1 cluster abundances constrain the $\Lambda$CDM parameters, which are the energy density of the total matter to $\Omega_{\mathrm{m}}=0.29^{+0.01}_{-0.02}$, and the normalization of the density fluctuations to $\sigma_8=0.88\pm0.02$ and their combination yields $S_8=\sigma_8 (\Omega_\mathrm{m} / 0.3)^{0.5}=0.86\pm0.01$, consistent and at a similar precision with the state-of-the-art CMB measurements. eRASS1 cosmological experiment places a most stringent upper limit on the summed masses of left-handed light neutrinos to $\sum m_\nu< 0.22\mathrm{~eV}$ (95\% confidence interval). Combining eRASS1 cluster abundance measurements with CMB and ground-based neutrino oscillation experiments, we measure the summed neutrino masses to be $\sum m_\nu=0.08_{-0.02}^{+0.03}\mathrm{~eV}$ or $\sum m_\nu=0.12_{-0.01}^{+0.03}\mathrm{~eV}$ depending on the mass hierarchy scenario for neutrino eigenstates. eRASS1 cluster abundances significantly improve the constraints on the dark energy equation of state parameter to $w=-1.12\pm0.12$. (ABRIDGED), Comment: 41 pages, 22 figures, Accepted for publication by A&A
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- 2024
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17. First Study of the Supernova Remnant Population in the Large Magellanic Cloud with eROSITA
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Zangrandi, Federico, Jurk, Katharina, Sasaki, Manami, Knies, Jonathan, Filipovic, Miroslav D., Haberl, Frank, Kavanagh, Patrick, Maitra, Chandreyee, Maggi, Pierre, Saeedi, Sara, Bernreuther, Dominic, Koribalski, Baerbel, Points, Sean, and Staveley-Smith, Lister
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Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Astrophysics of Galaxies - Abstract
The study of the entire population of SNRs in a galaxy helps us to understand the underlying stellar populations, the environments, in which the SNRs are evolving, and the stellar feedback on the ISM. The all-sky survey carried out by the extended Roentgen Survey with an Imaging Telescope Array (eROSITA) on board Spektrum-Roentgen-Gamma (Spektr-RG, SRG) has provided us with spatially and spectrally resolved X-ray data of the entire Large Magellanic Cloud (LMC) and its immediate surroundings in the soft X-ray band down to 0.2 keV. We performed a multiwavelength analysis of previously known SNR candidates and newly detected SNRs and SNR candidates. We applied the Gaussian gradient magnitude (GGM) filter to the eROSITA images of the LMC to highlight the edges of the shocked gas in order to find new SNRs. We compared the X-ray images with those of their optical and radio counterparts to investigate the true nature of the extended emission. We used the Magellanic Cloud Emission Line Survey (MCELS) for the optical data. For the radio comparison, we used data from the Australian Square Kilometre Array Pathfinder (ASKAP) survey of the LMC. Using the VISTA survey of the Magellanic Clouds (VMC) we have investigated the possible progenitors of the new SNRs and SNR candidates in our sample. We present the most updated catalogue of SNRs in the LMC. The eROSITA data have allowed us to confirm 1 of the previous SNR candidates and discover 16 new extended sources. We confirm 3 of them as new SNRs, while we propose the remaining 13 as new X-ray SNR candidates. We also present the first analysis of the follow-up XMM-Newton observation of MCSNR J0456-6533 discovered with eROSITA. Among the new candidates, we propose J0614-7251 (4eRASSU J061438.1-725112) as the first X-ray SNR candidate in the outskirts of the LMC., Comment: Paper accepted on 03.10.2024 in A&A journal. Paper in press
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- 2024
18. The hot circumgalactic medium in the eROSITA All-Sky Survey II. Scaling relations between X-ray luminosity and galaxies' mass
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Zhang, Yi, Comparat, Johan, Ponti, Gabriele, Merloni, Andrea, Nandra, Kirpal, Haberl, Frank, Truong, Nhut, Pillepich, Annalisa, Locatelli, Nicola, Zhang, Xiaoyuan, Sanders, Jeremy, Zheng, Xueying, Liu, Ang, Popesso, Paola, Liu, Teng, Predehl, Peter, Salvato, Mara, Shreeram, Soumya, and Yeung, Michael C. H.
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Astrophysics - Astrophysics of Galaxies ,Astrophysics - High Energy Astrophysical Phenomena - Abstract
Understanding how the properties of galaxies relate to the properties of the hot circum-galactic medium (CGM) around them can constrain galaxy evolution models. We measured the X-ray luminosity of the hot CGM based on the surface brightness profiles of central galaxy samples measured from Spectrum Roentgen Gamma (SRG)/eROSITA all-sky survey data. We related the X-ray luminosity to the galaxies' stellar and halo mass, and we compared the observed relations to the self-similar model and intrinsic (i.e., not forward-modeled) output of the IllustrisTNG, EAGLE, and SIMBA simulations. The average hot CGM X-ray luminosity ($L_{\rm X,CGM}$) correlates with the galaxy's stellar mass ($M_*$). It increases from $(1.6 \pm 2.1)\times10^{39} \rm erg\,s^{-1}$ to $(3.4 \pm 0.3)\times10^{41} \rm erg\,s^{-1}$, when $\log(M_*)$ increases from 10.0 to 11.5. A power law describes the correlation as $\log(L_{\rm X,CGM})= (2.4\pm 0.1)\times \log(M_*)+(14.6\pm1.5)$. The hot CGM X-ray luminosity as a function of halo mass is measured within $\log(M_{\rm 500c})=11.3-13.7$, extending our knowledge of the scaling relation by more than two orders of magnitude. $L_{\rm X,CGM}$ increases with $M_{\rm 500c}$ from $(3.0 \pm 1.6)\times10^{39}\ \rm erg\,s^{-1}$ at $\log(M_{\rm 500c})=11.3$ to $(1.3 \pm 0.1)\times10^{42}\ \rm erg\,s^{-1}$ at $\log(M_{\rm 500c})=13.7$. The relation follows a power law of $\log(L_{\rm X,CGM})= (1.32\pm 0.05)\times \log(M_{\rm 500c})+(24.1\pm0.7)$. Our observations highlight the necessity of non-gravitational processes at the galaxy group scale while suggesting these processes are sub-dominant at the galaxy scale. We show that the outputs of current cosmological galaxy simulations generally align with the observational results uncovered here but with possibly important deviations in selected mass ranges., Comment: Abstract abridged for arXiv submission, accepted by A&A
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- 2024
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19. The hot circumgalactic medium in the eROSITA All-Sky Survey I. X-ray surface brightness profiles
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Zhang, Yi, Comparat, Johan, Ponti, Gabriele, Merloni, Andrea, Nandra, Kirpal, Haberl, Frank, Locatelli, Nicola, Zhang, Xiaoyuan, Sanders, Jeremy, Zheng, Xueying, Liu, Ang, Popesso, Paola, Liu, Teng, Truong, Nhut, Pillepich, Annalisa, Predehl, Peter, Salvato, Mara, Shreeram, Soumya, Yeung, Michael C. H., and Ni, Qingling
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Astrophysics - Astrophysics of Galaxies ,Astrophysics - High Energy Astrophysical Phenomena - Abstract
The circumgalactic medium (CGM) provides the material needed for galaxy formation and influences galaxy evolution. The hot ($T>10^6K$) CGM is poorly detected around galaxies with stellar masses ($M_*$) lower than $3\times10^{11}M_\odot$ due to the low surface brightness. We used the X-ray data from the first four SRG/eROSITA All-Sky Surveys (eRASS:4). Based on the SDSS spectroscopic survey and halo-based group finder algorithm, we selected central galaxies with spectroscopic redshifts of $z_{\rm spec}<0.2$ and stellar masses of $10.0<\log(M_*/M_\odot)<11.5$ (85,222 galaxies) -- or halo masses of $11.5<\log(M_{\rm 200m}/M_\odot)<14.0$ (125,512 galaxies). By stacking the X-ray emission around galaxies, masking the detected X-ray point sources and carefully modeling the X-ray emission from the unresolved active galactic nuclei (AGN) and X-ray binaries (XRB), we obtain the X-ray emission from the hot CGM. We detected the X-ray emission around MW-mass and more massive central galaxies extending up to the virial radius ($R_{\rm vir}$). We used a $\beta$ model to describe the X-ray surface brightness profile and found $\beta =0.43^{+0.10}_{-0.06}\,(0.37^{+0.04}_{-0.02})$ for MW-mass (M31-mass) galaxies.We estimated the baryon budget of the hot CGM and obtained a value that is lower than the prediction of $\Lambda$CDM cosmology, indicating significant gas depletion in these halos. We extrapolated the hot CGM profile measured within $R_{\rm vir}$ to larger radii and found that within $\approx 3 R_{\rm vir}$, the baryon budget is close to the $\Lambda$CDM cosmology prediction. Our results set a firm footing for the presence of the hot CGM around such galaxies. These measurements constitute a new benchmark for galaxy evolution models and possible implementations of feedback processes therein., Comment: Abstract abridged for arXiv submission, accepted by A&A
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- 2024
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20. eRASSUJ060839.5-704014: A double degenerate ultra-compact binary in the direction of the LMC
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Maitra, C., Haberl, F., Vasilopoulos, G., Rau, A., Schwope, A., Friedrich, S., Buckley, D. A. H., Valdes, F., Lang, D., and Macfarlane, S. A.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
Context. During four all-sky surveys (eRASS1--4), eROSITA, the soft X-ray instrument aboard Spektrum-Roentgen-Gamma (SRG) detected a new supersoft X-ray source, eRASSU J060839.5-704014, in the direction of the Large Magellanic Cloud (LMC). Methods. We arranged follow-up observations in the X-ray and optical wavelengths and further searched in archival observations to reveal the nature of the object. Results. We discover pulsations at ~374 s with a pulse profile consistent with 100% modulation. We identify two other periodicities in the eROSITA data, which we establish as aliases due to the sampling of the eROSITA light curve. We identify a multi-wavelength counterpart to the X-ray source in UVW1 and g, r, i, and z images obtained by the optical/UV monitor on XMM-Newton and the Dark Energy Camera at the Cerro Tololo Inter-American Observatory. The timing and spectral characteristics of the source are consistent with a double degenerate ultra-compact binary system in the foreground of the LMC. eRASSU J060839.5-704014 belongs to a rare class of AM CVns, which are important to study in the context of progenitors of SN Ia and for persistent gravitational wave detection. Conclusions. We identify eRASSU J060839.5-704014 as a new double degenerate ultra-compact binary located in the foreground of the LMC., Comment: 12 pages, 13 figures, accepted for publication in A&A
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- 2024
21. Discovery of the Goat Horn complex: a $\sim 1000$ deg$^2$ diffuse X-ray source connected to radio loop XII
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Locatelli, Nicola, Ponti, Gabriele, Merloni, Andrea, Zheng, Xueying, Dennerl, Konrad, Haberl, Frank, Maitra, Chandreyee, Sanders, Jeremy, Sasaki, Manami, and Zhang, Heshou
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Astrophysics - Astrophysics of Galaxies - Abstract
A dozen of patches of polarized radio emission spanning tens of degrees in the form of coherent and stationary loops are observed at radio frequencies across the sky. Their origin is usually associated to nearby shocks, possibly arising from close supernovae explosions. The origin of the radio Loop XII remains so far unknown. We report an anti-correlation of the radio polarized emission of loop XII with a large patch of soft X-ray emission found with SRG/eROSITA in excess of the background surface brightness, in the same region. The soft X-ray seemingly coherent patch in excess of the background emission, which we dub as the Goat Horn complex, extends over a remarkable area of $\sim 1000$ deg$^2$ and includes an arc-shaped enhancement potentially tracing a cold front. An anti-correlation of the X-ray intensity with the temperature of the plasma responsible for the X-ray emission is also observed. The X-ray bright arc seems to anticipate the radio loop XII by some degrees on the sky. This behavior can be recast in terms of a correlation between X-ray surface brightness and radio depolarization. We explore and discuss different possible scenarios for the source of the diffuse emission in the Goat Horn complex: a large supernova remnant; an outflow from active star formation regions in nearby Galactic spiral arms; a hot atmosphere around the Large Magellanic Cloud. In order to probe these scenarios further, a more detailed characterization on the velocity of the hot gas is required., Comment: 12 pages, 14 figures
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- 2024
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22. Detection of pulsed X-ray emission from the isolated neutron star candidate eRASSU J131716.9-402647
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Kurpas, J., Schwope, A. D., Pires, A. M., and Haberl, F.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
The X-ray source eRASSU J131716.9-402647 was recently identified from observations with Spectrum Roentgen Gamma (SRG)/eROSITA as a promising X-ray dim isolated neutron star (XDINS) candidate on the premise of a soft energy distribution, absence of catalogued counterparts, and a high X-ray-to-optical flux ratio. Here, we report the results of a multi-wavelength observational campaign with XMM-Newton, NICER and the FORS2 instrument at the ESO-VLT. We found in both the XMM-Newton and NICER data that the X-ray emission is strongly pulsed at a period of $12.757$ s (pulsed fraction $p_\mathrm{f} = (29.1 \pm 2.6)$% in the 0.2-2 keV band). The pulse profile is double-humped, and the pulsed fraction increases with energy. The XMM-Newton and NICER epochs allow us to derive a 3$\sigma$ upper limit of $\dot{P}\leq 8\times 10^{-11}$ s s$^{-1}$ on the spin-down rate of the neutron star. The source spectrum is well described by a purely thermal continuum, either a blackbody with $kT\sim95$ eV or a magnetised neutron star atmosphere model with $kT \sim 35$ eV. Similarly to other thermally emitting isolated neutron stars, we found in either case strong deviations from the continuum, a broad absorption feature at energy $\sim260$ eV and a narrow one around $590$ eV. The FORS2 instrument at ESO-VLT has not detected the optical counterpart ($m_\mathrm{R}>27.5$ mag, $5\sigma$ detection limit), implying an X-ray-to-optical flux ratio of $10^4$ at least. The properties of eRASSU J131716.9-402647 strongly resemble those of a highly magnetised isolated neutron star and favour an XDINS or high-B pulsar nature., Comment: 11 pages, 9 figures, accepted for publication in A&A
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- 2024
23. The eROSITA DR1 variability catalogue
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Boller, Th., Freyberg, M., Buchner, J., Haberl, F., Maitra, C., Schwope, A., Robrade, J., Rau, A., Grotova, I., Waddell, S., Ni, Q., Salvato, M., Krumpe, M., Georgakakis, A., Merloni, A., and Nandra, K.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
The extended ROentgen Survey with an Imaging Telescope Array (eROSITA) on board the Spectrum-Roentgen-Gamma (SRG) mission with its first All-Sky Survey (eRASS1) has offered an unprecedented, comprehensive view of the variable X-ray sky. With enhanced sensitivity, broader energy coverage, and improved resolution compared to prior surveys, the eRASS1 Data Release 1 (DR1) catalogue underwent a variability analysis, focusing on a substantial subset of 128,669 sources. We performed multiple variability tests, utilizing conventional normalized excess variance, maximum amplitude variability, and Bayesian excess variance methods. Among the 128,669 DR1 sources, our research identified 557 objects exhibiting variability through NEV and AMPLMAX tests. After applying suitable thresholds, 108 sources demonstrated significant variability via NEV, while 73 did so through AMPLMAX. The utilization of the bexvar method extended our detection capabilities to lower count rates, unveiling a total of 1307 sources manifesting variability. Furthermore, our comparative analysis spanning 2.5 years encompassed observations from consecutive eROSITA surveys, eRASS2, eRASS3, eRASS4, and eRASS5. Notably, the Gamma-ray burst afterglow GRB 200120A, which was the most variable DR1 source, was as expected absent in subsequent eROSITA survey scans. Observations of the Low-Mass X-ray Binary GX 339-4 across various eROSITA survey scans unveiled substantial variability. These outbursts involve the movement of the inner radius of the accretion disk, fluctuating inward and outward. Combining eROSITA and MAXI data reveals that the most effective tracer for monitoring the onset of the outbursts is the softest eROSITA band. Magnetically active stars are commonly found among the more variable X-ray sources. We analyzed the AGN sample to identify variability patterns and instances of efficiency limit violations., Comment: 13 pages, 10 figures
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- 2024
24. The SRG/eROSITA all-sky survey: First X-ray catalogues and data release of the western Galactic hemisphere
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Merloni, A., Lamer, G., Liu, T., Ramos-Ceja, M. E., Brunner, H., Bulbul, E., Dennerl, K., Doroshenko, V., Freyberg, M. J., Friedrich, S., Gatuzz, E., Georgakakis, A., Haberl, F., Igo, Z., Kreykenbohm, I., Liu, A., Maitra, C., Malyali, A., Mayer, M. G. F., Nandra, K., Predehl, P., Robrade, J., Salvato, M., Sanders, J. S., Stewart, I., Tubín-Arenas, D., Weber, P., Wilms, J., Arcodia, R., Artis, E., Aschersleben, J., Avakyan, A., Aydar, C., Bahar, Y. E., Balzer, F., Becker, W., Berger, K., Boller, T., Bornemann, W., Brüggen, M., Brusa, M., Buchner, J., Burwitz, V., Camilloni, F., Clerc, N., Comparat, J., Coutinho, D., Czesla, S., Dannhauer, S. M., Dauner, L., Dauser, T., Dietl, J., Dolag, K., Dwelly, T., Egg, K., Ehl, E., Freund, S., Friedrich, P., Gaida, R., Garrel, C., Ghirardini, V., Gokus, A., Grünwald, G., Grandis, S., Grotova, I., Gruen, D., Gueguen, A., Hämmerich, S., Hamaus, N., Hasinger, G., Haubner, K., Homan, D., Chitham, J. Ider, Joseph, W. M., Joyce, A., König, O., Kaltenbrunner, D. M., Khokhriakova, A., Kink, W., Kirsch, C., Kluge, M., Knies, J., Krippendorf, S., Krumpe, M., Kurpas, J., Li, P., Liu, Z., Locatelli, N., Lorenz, M., Müller, S., Magaudda, E., Mannes, C., McCall, H., Meidinger, N., Michailidis, M., Migkas, K., Muñoz-Giraldo, D., Musiimenta, B., Nguyen-Dang, N. T., Ni, Q., Olechowska, A., Ota, N., Pacaud, F., Pasini, T., Perinati, E., Pires, A. M., Pommranz, C., Ponti, G., Poppenhaeger, K., Pühlhofer, G., Rau, A., Reh, M., Reiprich, T. H., Roster, W., Saeedi, S., Santangelo, A., Sasaki, M., Schmitt, J., Schneider, P. C., Schrabback, T., Schuster, N., Schwope, A., Seppi, R., Serim, M. M., Shreeram, S., Sokolova-Lapa, E., Starck, H., Stelzer, B., Stierhof, J., Suleimanov, V., Tenzer, C., Traulsen, I., Trümper, J., Tsuge, K., Urrutia, T., Veronica, A., Waddell, S. G. H., Willer, R., Wolf, J., Yeung, M. C. H., Zainab, A., Zangrandi, F., Zhang, X., Zhang, Y., and Zheng, X.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
The eROSITA telescope array aboard the Spektrum Roentgen Gamma (SRG) satellite began surveying the sky in December 2019, with the aim of producing all-sky X-ray source lists and sky maps of an unprecedented depth. Here we present catalogues of both point-like and extended sources using the data acquired in the first six months of survey operations (eRASS1; completed June 2020) over the half sky whose proprietary data rights lie with the German eROSITA Consortium. We describe the observation process, the data analysis pipelines, and the characteristics of the X-ray sources. With nearly 930000 entries detected in the most sensitive 0.2-2.3 keV energy range, the eRASS1 main catalogue presented here increases the number of known X-ray sources in the published literature by more than 60%, and provides a comprehensive inventory of all classes of X-ray celestial objects, covering a wide range of physical processes. A smaller catalogue of 5466 sources detected in the less sensitive but harder 2.3-5 keV band is the result of the first true imaging survey of the entire sky above 2 keV. We show that the number counts of X-ray sources in eRASS1 are consistent with those derived over narrower fields by past X-ray surveys of a similar depth, and we explore the number counts variation as a function of the location in the sky. Adopting a uniform all-sky flux limit (at 50% completeness) of F_{0.5-2 keV} > 5 \times 10^{-14}$ erg\,s$^{-1}$\,cm$^{-2}$, we estimate that the eROSITA all-sky survey resolves into individual sources about 20% of the cosmic X-ray background in the 1-2 keV range. The catalogues presented here form part of the first data release (DR1) of the SRG/eROSITA all-sky survey. Beyond the X-ray catalogues, DR1 contains all detected and calibrated event files, source products (light curves and spectra), and all-sky maps. Illustrative examples of these are provided., Comment: 39 pages, 23 figures. Accepted for publication in A&A. Accompanying eROSITA-DE Data Release 1
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- 2024
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25. IEEE BigData 2023 Keystroke Verification Challenge (KVC)
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Stragapede, Giuseppe, Vera-Rodriguez, Ruben, Tolosana, Ruben, Morales, Aythami, DeAndres-Tame, Ivan, Damer, Naser, Fierrez, Julian, Garcia, Javier-Ortega, Gonzalez, Nahuel, Shadrikov, Andrei, Gordin, Dmitrii, Schmitt, Leon, Wimmer, Daniel, Grossmann, Christoph, Krieger, Joerdis, Heinz, Florian, Krestel, Ron, Mayer, Christoffer, Haberl, Simon, Gschrey, Helena, Yamagishi, Yosuke, Saha, Sanjay, Rasnayaka, Sanka, Wickramanayake, Sandareka, Sim, Terence, Gutfeter, Weronika, Baran, Adam, Krzyszton, Mateusz, and Jaskola, Przemyslaw
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Computer Science - Computer Vision and Pattern Recognition - Abstract
This paper describes the results of the IEEE BigData 2023 Keystroke Verification Challenge (KVC), that considers the biometric verification performance of Keystroke Dynamics (KD), captured as tweet-long sequences of variable transcript text from over 185,000 subjects. The data are obtained from two of the largest public databases of KD up to date, the Aalto Desktop and Mobile Keystroke Databases, guaranteeing a minimum amount of data per subject, age and gender annotations, absence of corrupted data, and avoiding excessively unbalanced subject distributions with respect to the considered demographic attributes. Several neural architectures were proposed by the participants, leading to global Equal Error Rates (EERs) as low as 3.33% and 3.61% achieved by the best team respectively in the desktop and mobile scenario, outperforming the current state of the art biometric verification performance for KD. Hosted on CodaLab, the KVC will be made ongoing to represent a useful tool for the research community to compare different approaches under the same experimental conditions and to deepen the knowledge of the field., Comment: 9 pages, 10 pages, 2 figures. arXiv admin note: text overlap with arXiv:2311.06000
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- 2024
26. The MeerKAT 1.3 GHz Survey of the Small Magellanic Cloud
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Cotton, W., Filipovic, M. D., Camilo, F., Indebetouw, R., Alsaberi, R. Z. E., Anih, J. O., Baker, M., Bastian, T . S., Bojicic, I., Carli, E., Cavallaro, F., Crawford, E. J., Dai, S., Haberl, F., Levin, L., Luken, K., Pennock, C . M., Rajabpour, N., Stappers, B. W., van Loon, J. Th., Zijlstra, A. A., Buchner, S., Geyer, M., Goedhart, S., and Serylak, M.
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Astrophysics - Astrophysics of Galaxies - Abstract
We present new radio continuum images and a source catalogue from the MeerKAT survey in the direction of the Small Magellanic Cloud (SMC). The observations, at a central frequency of 1.3 GHz across a bandwidth of 0.8 GHz, encompass a field of view ~7 x 7 degrees and result in images with resolution of 8 arcsec. The median broad-band Stokes I image Root Mean Squared noise value is ~11 microJy/beam. The catalogue produced from these images contains 108,330 point sources and 517 compact extended sources. We also describe a UHF (544-1088 MHz) single pointing observation. We report the detection of a new confirmed Supernova Remnant (SNR) (MCSNR J0100-7211) with an X-ray magnetar at its centre and 10 new SNR candidates. This is in addition to the detection of 21 previously confirmed SNRs and two previously noted SNR candidates. Our new SNR candidates have typical surface brightness an order of magnitude below those previously known, and on the whole they are larger. The high sensitivity of the MeerKAT survey also enabled us to detect the bright end of the SMC Planetary Nebulae (PNe) sample - point-like radio emission is associated with 38 of 102 optically known PNe, of which 19 are new detections. Lastly, we present the detection of three foreground radio stars amidst 11 circularly polarised sources, and a few examples of morphologically interesting background radio galaxies from which the radio ring galaxy ESO 029-G034 may represent a new type of radio object., Comment: 31 pages, 27 figures
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- 2024
27. Multicenter PET image harmonization using generative adversarial networks
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Haberl, David, Spielvogel, Clemens P., Jiang, Zewen, Orlhac, Fanny, Iommi, David, Carrió, Ignasi, Buvat, Irène, Haug, Alexander R., and Papp, Laszlo
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- 2024
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28. Comparison of discovery rates and prognostic utility of [68Ga]Ga-PSMA-11 PET/CT and circulating tumor DNA in prostate cancer—a cross-sectional study
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Kluge, Kilian, Einspieler, Holger, Haberl, David, Spielvogel, Clemens, Amereller, Dominik, Egger, Gerda, Kramer, Gero, Grubmüller, Bernhard, Shariat, Shahrokh, Hacker, Marcus, Kenner, Lukas, and Haug, Alexander
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- 2024
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29. Demand-side strategies key for mitigating material impacts of energy transitions
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Creutzig, Felix, Simoes, Sofia G., Leipold, Sina, Berrill, Peter, Azevedo, Isabel, Edelenbosch, Oreane, Fishman, Tomer, Haberl, Helmut, Hertwich, Edgar, Krey, Volker, Lima, Ana Teresa, Makov, Tamar, Mastrucci, Alessio, Milojevic-Dupont, Nikola, Nachtigall, Florian, Pauliuk, Stefan, Silva, Mafalda, Verdolini, Elena, van Vuuren, Detlef, Wagner, Felix, Wiedenhofer, Dominik, and Wilson, Charlie
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- 2024
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30. Zielsetzung
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Haberl-Glantschnig, Heidi, Janauschek, Katharina, Haberl-Glantschnig, Heidi, and Janauschek, Katharina
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- 2024
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31. Von Blockaden und inneren Schätzen
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Haberl-Glantschnig, Heidi, Janauschek, Katharina, Haberl-Glantschnig, Heidi, and Janauschek, Katharina
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- 2024
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32. Das Abrufen von Ressourcen und Stärken als Katalysator für Wachstum
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Haberl-Glantschnig, Heidi, Janauschek, Katharina, Haberl-Glantschnig, Heidi, and Janauschek, Katharina
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- 2024
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33. Beyond Words: Angewandtes Business Mentalcoaching im Führungs- und Businessalltag
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Haberl-Glantschnig, Heidi, Janauschek, Katharina, Haberl-Glantschnig, Heidi, and Janauschek, Katharina
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- 2024
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34. Die Wiege der Veränderung – die Macht des Unbewussten nutzen
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Haberl-Glantschnig, Heidi, Janauschek, Katharina, Haberl-Glantschnig, Heidi, and Janauschek, Katharina
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- 2024
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35. Erfolgreiche Mentalstrategien aus Spitzensport, Gesellschaft und Leben
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Haberl-Glantschnig, Heidi, Janauschek, Katharina, Haberl-Glantschnig, Heidi, and Janauschek, Katharina
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- 2024
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36. Über die Autorinnen und die theoretische Basis des Business Mentalcoaching
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Haberl-Glantschnig, Heidi, Janauschek, Katharina, Haberl-Glantschnig, Heidi, and Janauschek, Katharina
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- 2024
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37. Was ist Business Mentalcoaching?
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Haberl-Glantschnig, Heidi, Janauschek, Katharina, Haberl-Glantschnig, Heidi, and Janauschek, Katharina
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- 2024
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38. Grundkompetenzen im Business Mentalcoaching
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Haberl-Glantschnig, Heidi, Janauschek, Katharina, Haberl-Glantschnig, Heidi, and Janauschek, Katharina
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- 2024
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39. Sprungkraft entfaltender Wirkprozess
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Haberl-Glantschnig, Heidi, Janauschek, Katharina, Haberl-Glantschnig, Heidi, and Janauschek, Katharina
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- 2024
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40. Grundhaltungen und Rollenklärung als Business Mentalcoach
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Haberl-Glantschnig, Heidi, Janauschek, Katharina, Haberl-Glantschnig, Heidi, and Janauschek, Katharina
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- 2024
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41. TFEB activation hallmarks antigenic experience of B lymphocytes and directs germinal center fate decisions
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Matthias Münchhalfen, Richard Görg, Michael Haberl, Jens Löber, Jakob Willenbrink, Laura Schwarzt, Charlotte Höltermann, Christian Ickes, Leonard Hammermann, Jan Kus, Björn Chapuy, Andrea Ballabio, Sybille D. Reichardt, Alexander Flügel, Niklas Engels, and Jürgen Wienands
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Science - Abstract
Abstract Ligation of the B cell antigen receptor (BCR) initiates humoral immunity. However, BCR signaling without appropriate co-stimulation commits B cells to death rather than to differentiation into immune effector cells. How BCR activation depletes potentially autoreactive B cells while simultaneously primes for receiving rescue and differentiation signals from cognate T lymphocytes remains unknown. Here, we use a mass spectrometry-based proteomic approach to identify cytosolic/nuclear shuttling elements and uncover transcription factor EB (TFEB) as a central BCR-controlled rheostat that drives activation-induced apoptosis, and concurrently promotes the reception of co-stimulatory rescue signals by supporting B cell migration and antigen presentation. CD40 co-stimulation prevents TFEB-driven cell death, while enhancing and prolonging TFEB’s nuclear residency, which hallmarks antigenic experience also of memory B cells. In mice, TFEB shapes the transcriptional landscape of germinal center B cells. Within the germinal center, TFEB facilitates the dark zone entry of light-zone-residing centrocytes through regulation of chemokine receptors and, by balancing the expression of Bcl-2/BH3-only family members, integrates antigen-induced apoptosis with T cell-provided CD40 survival signals. Thus, TFEB reprograms antigen-primed germinal center B cells for cell fate decisions.
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- 2024
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42. Advancing hull monitoring through physics-informed machine learning: Towards a real-time approach
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Haberl, S., primary, Eid, S.A., additional, and Ehlers, S., additional
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- 2024
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43. Black Box or Open Science? Assessing Reproducibility-Related Documentation in AI Research.
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Florian Koenigstorfer, Armin Haberl, Dominik Kowald, Tony Ross-Hellauer, and Stefan Thalmann
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- 2024
44. Incremental Role of Radiomics and Artificial Intelligence
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Papp, Laszlo, Spielvogel, Clemens, Haberl, David, Ecsedi, Boglarka, Lopci, Egesta, editor, and Mansi, Luigi, editor
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- 2024
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45. Was bei der HIV-Therapie von Menschen aus der Ukraine zu beachten ist
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Haberl, Annette and Khaykin, Pavel
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- 2024
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46. Colloidal Stability and Surface Chemistry Are Key Factors for the Composition of the Protein Corona of Inorganic Gold Nanoparticles
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Johnston, Blair D., primary, Kreyling, Wolfgang G., additional, Pfeiffer, Christian, additional, Schäffler, Martin, additional, Sarioglu, Hakan, additional, Ristig, Simon, additional, Hirn, Stephanie, additional, Haberl, Nadine, additional, Thalhammer, Stefan, additional, Hauck, Stefanie M., additional, Semmler-Behnke, Manuela, additional, Epple, Matthias, additional, Hühn, Jonas, additional, Del Pino, Pablo, additional, and Parak, Wolfgang J., additional
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- 2024
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47. In Vivo Integrity of Polymer-Coated Gold Nanoparticles
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Kreyling, Wolfgang G., primary, Abdelmonem, Abuelmagd M., additional, Ali, Zulqurnain, additional, Alves, Frauke, additional, Geiser, Marianne, additional, Haberl, Nadine, additional, Hartmann, Raimo, additional, Hirn, Stephanie, additional, Jimenez de Aberasturi, Dorleta, additional, Kantner, Karsten, additional, Khadem-Saba, Gulnaz, additional, Montenegro, Jose-Maria, additional, Rejman, Joanna, additional, Rojo, Teofilo, additional, de Larramendi, Idoia Ruiz, additional, Ufartes, Roser, additional, Wenk, Alexander, additional, and Parak, Wolfgang J., additional
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- 2024
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48. Effect of In Vitro Digestion on Bioactive Peptides Related to Immune and Gut Health in Intact Cow’s Milk and Hydrolyzed Protein-Based Infant Formulas
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Gabriela Grigorean, Xiaogu Du, Russell Kuhfeld, Elisabeth M. Haberl, and Bo Lönnerdal
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bioactive peptides ,infant formula ,extensively hydrolyzed infant formulas (eHFs) ,intact protein formulas (iPFs) ,immune health ,gut health ,Nutrition. Foods and food supply ,TX341-641 - Abstract
Background/Objectives: Human milk is the optimal source of nutrition and protection against infection for infants. If breastfeeding is not possible, standard and hydrolyzed infant formulas (IF) are an alternative. Extensively hydrolyzed IFs (eHFs) contain bioactive peptides, but their activities have rarely been evaluated. The aim of this study was to characterize and compare the bioactive peptide profiles of different eHFs and standard IFs before and after in vitro digestion. Methods: Two forms, liquid and powder, of intact protein formula (iPF) and eHF were subjected to in vitro gastrointestinal digestion, mimicking a young infant’s gut (age 0–4 months) and an older infant’s gut (>6 months). Bioactive peptides of in vitro digested and undigested formulas were analysed with Liquid Chromatography–Mass Spectrometry (LC–MS). Results: In all samples, a variety of peptides with potential bioactive properties were found. Immuno-regulatory peptides, followed by antimicrobial and antioxidative peptides were most frequent, as were peptides promoting wound healing, increasing mucin secretion, regulating cholesterol metabolism, and preventing bacterial infection. Peptides typically found in yoghurt and colostrum were identified in some formula samples. Conclusions: The high amounts of bioactive peptides with various properties in eHFs and iPFs indicate a possible contribution to infection protection, healthy gut microbiomes, and immunological development of infants. eHFs showed similar compositions of bioactive peptides to iPFs, with intermittently increased peptide variety and quantity.
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- 2024
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49. Recreational Drug Overdose—Clinical Value of Toxicological Analysis
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Tobias Zellner, Florian Eyer, Christian Rabe, Stefanie Geith, Bettina Haberl, and Sabrina Schmoll
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toxicological analysis ,clinical relevance ,recreational drug overdose ,opiate/opioid ,benzodiazepine/Z-drug ,NPS ,Chemical technology ,TP1-1185 - Abstract
Background: Toxicological analysis of patients with acute recreational drug poisoning can improve our understanding of substance use patterns, clinical symptoms, and improve treatment. Patient history alone may be incomplete or misleading. The objective was to assess the differences in patient history and analytical results, to describe the clinical characteristics, implications and hospital management, and to describe the drug use pattern over time. Methods: A retrospective study including all patients admitted to our toxicology unit with recreational drug toxicity and analytical testing from October 2014 to December 2022. Results: 872 patients were included. Patient history revealed a median of one ingested substance class: opiates/opioids, benzodiazepines/Z-drugs, and Pregabalin were predominant. Urine analysis revealed a median of three ingested substance classes (p < 0.001). Benzodiazepines/Z-drugs, Pregabalin, and THC were severely underreported. Agitation and aggression, anxiety, hallucinations, and psychosis were frequent, associated with cocaine, cathinone/phenethylamine, and amphetamine/MDMA detection and required sedation. Coma was also frequent, associated with opiate/opioid, benzodiazepine/Z-drug, GBL/GHB, and Pregabalin detection and required intubation, and/or application of Naloxone and/or Flumazenil. Twelve patients arrived in cardiac arrest; all were positive for opiates/opioids. Four patients died: three with Benzodiazepines/Z-drugs, Pregabalin and opiates/opioids detected, one with cathinones/phenethylamines detected. While cathinones/phenethylamines and synthetic cannabinoid receptor agonists were mainly detected between 2014–2016, detection decreased significantly between 2017–2022 after NPS legislation passed. Pregabalin detection increased. Conclusions: Patient history is inaccurate, and patients frequently underreport ingested drugs. Opiates and opioids are still the main cause of morbidity and mortality. Pregabalin is increasingly abused. NPS legislation effectively decreased cathinone/phenethylamine and synthetic cannabinoid receptor agonist overdoses.
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- 2024
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50. POLarizer-FENestration (POLFEN) a novel concept of a glazing technology to modulate daylighting and glare in buildings
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Kota, Sandeep Joshua and Haberl, Jeff S.
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- 2024
- Full Text
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