1. Improvement and exploration of potassium-competitive acid blockers dual therapy for the eradication of Helicobacter pylori.
- Author
-
CHEN Weiwei, PENG Ruolin, QU Yi, and ZHANG Zhenyu
- Subjects
- *
HELICOBACTER pylori , *HELICOBACTER pylori infections , *PROTON pump inhibitors , *ATROPHIC gastritis , *GASTROINTESTINAL diseases , *H2 receptor antagonists , *POTASSIUM antagonists - Abstract
Helicobacter pylori infection is an important causative factor in a variety of gastrointestinal diseases, such as atrophic gastritis, peptic ulcer disease, and gastric cancer. Timely eradication treatment is conducive to maintaining the health of patients. With the increase of drug resistance in Helicobacter pylori, dual therapy with proton pump inhibitors combined with high-dose amoxicillin has gradually gained attention. Potassium- competitive acid blockers are new types of antacids that have a faster onset of action and a longer lasting acid suppression effect than traditional proton pump inhibitors, making it more suitable for dual therapy. In recent years, scholars have carried out a lot of exploration, improvement and verification of potassium-competitive acid blockers dual therapy, and this article reviews its research progress. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF