1. Intraocular pressure increases the rate of macular vessel density loss in glaucoma
- Author
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Mahmoudinezhad, Golnoush, Moghimi, Sasan, Nishida, Takashi, Micheletti, Eleonora, Du, Kelvin H, Mohammadzadeh, Vahid, Wu, Jo-Hsuan, Kamalipour, Alireza, and Weinreb, Robert N
- Subjects
Biomedical and Clinical Sciences ,Ophthalmology and Optometry ,Clinical Research ,Neurosciences ,Aging ,Eye Disease and Disorders of Vision ,Neurodegenerative ,Eye ,Humans ,Glaucoma ,Glaucoma ,Open-Angle ,Intraocular Pressure ,Nerve Fibers ,Retinal Ganglion Cells ,Retinal Vessels ,Tomography ,Optical Coherence ,Visual Field Tests ,Intraocular pressure ,Macula ,Clinical Sciences ,Opthalmology and Optometry ,Public Health and Health Services ,Ophthalmology & Optometry ,Clinical sciences ,Ophthalmology and optometry - Abstract
Background/aimsTo evaluate the relationship over time between intraocular pressure (IOP) and the rate of macula whole image vessel density (wiVD) loss and whole image ganglion cell complex (wiGCC) thinning in glaucoma METHODS: From 62 patients in the Diagnostic Innovations in Glaucoma Study, 59 Primary open-angle glaucoma and 27 glaucoma suspect eyes with mean follow-up of 3.2 years were followed. Optical coherence tomography angiography (OCT-A)-based vessel density and OCT-based structural thickness of the same 6×6 mm GCC scan slab were evaluated. Univariable and multivariable linear mixed models were performed for all eyes and also a subset of them in which peak IOP
- Published
- 2024