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Introduction: Carpal tunnel syndrome (CTS) is the most common peripheral nerve entrapment disease, and it is a subject of great interest and concern to medical professionals and the general public. Our study aims to analyze and compare the quality and accuracy of the information related to CTS provided by social media platforms (SMPs) and the new large language models (LLM)., Methods: On YouTube, the first 20 videos in English and the first 20 videos in Spanish when searching for "carpal tunnel syndrome" and "síndrome túnel carpo" were selected. On Instagram, the first 20 videos with the hashtag #carpaltunnelsyndrome and #tunelcarpiano were chosen (in total 80 videos). Duration, number of likes, number of views, number of followers, upload date, and author category (medical specialist, patient, etc) were evaluated. Three specific questions about CTS were asked to 2 new LLMs (ChatGPT and Google Bard). The quality of information was analyzed and compared by two independent board-certified plastic surgeons using the Journal of American Medical Association (JAMA) and DISCERN scales., Results: LLMs showed a significant higher quality of information when compared with SMPs based on the DISCERN scores (P < 0.05). Average DISCERN scores for answers given by ChatGPT and Google Bard were 52.83 and 57.83, respectively (good quality). In YouTube and Instagram, the average score for the 80 videos based on the JAMA scale was 1.92 (low reliability) and 25.18 (very low quality) on the DISCERN scale. Videos created by medical professionals in SMPs were associated with a higher JAMA and DISCERN scores (P < 0.05). 53.8% of the videos were made by a nonmedical author., Conclusions: The quality of information from LLMs was good and significantly better than in SMP. A low participation of board-certified surgeons in SMP was found. Board-certified surgeons should be more involved in LLM and SMPs to increase leadership, improve education, and spread knowledge of peripheral nerve surgery., Competing Interests: Conflicts of interest and sources of funding: none declared., (Copyright © 2025 Wolters Kluwer Health, Inc. All rights reserved.)

Cellulose hydrogels derived from agave bagasse were formulated to promote the regeneration of gingival connective tissue in lagomorphs. Three treatment modalities were randomly implanted in the gingival diastema area in 16 rabbits. The general characteristics were analyzed and histopathological studies were carried out at 4, 8, 12, and 16 weeks. A chi-squared test was performed using IBM-SPSS version 25, indicating that cellulose hydrogels implanted in lagomorph's gingival tissue showed the presence of greater angiogenesis and fibrogenesis at the four evaluation intervals during 16 consecutive weeks. The presence of inflammatory infiltrates had no significant impact. No significant changes were observed in body weight and water and food intake. This suggests that hydrogels contribute to the regeneration and/or repair of oral connective tissue, showing angiogenesis and fibrogenesis in 50 to 100% of rabbits tested with hydrogel cellulose membrane. Regarding angiogenesis, in the specimens where membranes were implanted, its presence predominated in all variants (50%), followed by diffuse angiogenesis (37.5%), and finally the absence of angiogenesis (12.5%). [ABSTRACT FROM AUTHOR]