5 results on '"Clifton S"'
Search Results
2. The Hawaii Dust Regime: Patterns and Variability in Aerosol Mineral Dust From MERRA‐2 at Station ALOHA and the Hawaii Aerosol Time‐Series
- Author
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Ohnemus, Daniel C., Kollman, Charlotte, Marsay, Christopher M., Ricci, Mariah, and Buck, Clifton S.
- Abstract
The transport and delivery of low‐abundance, bioactive trace elements to the surface ocean by aerosol mineral dust is a major planetary control over marine primary production and hence the global carbon cycle. Variations in the concentration of atmospheric dust have established links to global climate over geologic timescales and to regional biogeographic shifts over seasonal timescales. Constraining atmospheric dust variability is thus of high value to understanding oceanographic systems, especially vast, constitutively low‐nutrient subtropical gyre ecosystems and high‐nutrient/low‐chlorophyll ecosystems where availability of the trace element iron is a dominant ecological control. Here we leverage the MERRA‐2 reanalysis product to examine over four decades of surface‐level atmospheric mineral dust concentrations in a domain of the subtropical North Pacific centered at Ocean Station ALOHA. This study region has been sampled regularly since the mid‐1980s and was the site of the Hawaii Aerosol Time‐Series (HATS) project in 2022–2023. Two unequal semi‐annual periods of elevated dust evident in the long‐term results are described and constrained. We look for evidence of shifts in total and seasonal atmospheric dust abundances or in the timing of the onset of the dominant spring/summer dusty period, finding year‐to‐year variations but little evidence for long‐term trends. We observe significant but complex relationships between the Pacific Decadal Oscillation (PDO) index and both dust and precipitation. The 2022 calendar year was among the dustiest years for the study domain in the preceding two decades and, by contrast, 2023 exhibited a significant early spring lull in dust. Dust blown from Earth's continents fertilizes the oceans with iron and other nutrients needed for plants to grow. This affects ocean ecosystems and is an important control on Earth's climate. Modern models for the atmosphere report dust very precisely in time and space but rarely address how it affects specific ocean sites over time. We examine these best‐available model outputs for a well‐studied site at Hawaii to improve our understanding of how dust has varied over the many decades this region has been studied by oceanographic and atmospheric researchers. Mineral dust concentrations from the MERRA‐2 atmospheric reanalysis product are investigated at Hawaii's ocean Station ALOHA back to 1980Two semi‐annual dust pulses at the site are described and little evidence is seen for long‐term shifts in total dust or pulse timingDust concentrations exhibit different periodicities and relationships with precipitation and Pacific Decadal Oscillation index Mineral dust concentrations from the MERRA‐2 atmospheric reanalysis product are investigated at Hawaii's ocean Station ALOHA back to 1980 Two semi‐annual dust pulses at the site are described and little evidence is seen for long‐term shifts in total dust or pulse timing Dust concentrations exhibit different periodicities and relationships with precipitation and Pacific Decadal Oscillation index
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- 2025
- Full Text
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3. Mapping Behavioral Research in Post-Treatment Cancer Care in Sub-Saharan Africa: A Scoping Review.
- Author
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Ogunsanya ME, Saintibert J, Bolajoko OO, Hooks D, Clifton S, and Odedina FT
- Subjects
- Humans, Africa South of the Sahara, Social Support, Social Stigma, Depression therapy, Depression psychology, Patient Acceptance of Health Care psychology, Anxiety psychology, Anxiety therapy, Survivorship, Cancer Survivors psychology, Cancer Survivors statistics & numerical data, Neoplasms psychology, Neoplasms therapy, Quality of Life
- Abstract
Objective: This scoping review explores the multifaceted experience of cancer survivorship in Sub-Saharan Africa (SSA), with a focus on the post-treatment phase. The primary objective is to examine the psychosocial, cultural, and economic factors that influence post-treatment survivorship care and outcomes., Methods: A comprehensive literature review was conducted using databases such as Web of Science Core Collection to identify studies published between 2000 and 2023. Eligible studies focused on post-treatment cancer survivorship in SSA. Data were extracted, analyzed, and synthesized to identify key themes and research gaps., Results: The review identified substantial psychological distress among survivors, including depression, anxiety, and insomnia, often exacerbated by financial toxicity and limited access to psychosocial support services. Cultural factors, such as spiritual beliefs, reliance on traditional healers, and cancer-related stigma, influenced healthcare-seeking behaviors and overall well-being. Despite these challenges, social support networks, religiosity, and targeted psychosocial interventions improved emotional resilience and quality of life. However, major gaps remain, including insufficient integration of cultural beliefs into survivorship care, inadequate long-term follow-up (LTFU) programs, limited oncofertility support, and a lack of regionally diverse and longitudinal data., Conclusions: Cancer survivorship in SSA is shaped by intricate psychosocial, cultural, and economic dynamics that extend beyond clinical care. Addressing these challenges requires culturally sensitive, evidence-based interventions, including financial counseling, spiritual care integration, and the establishment of structured LTFU programs. Additionally, expanding access to oncofertility support and integrating culturally relevant psychosocial services can further enhance survivorship outcomes. Strengthening collaboration between policymakers, healthcare providers, and researchers-through interdisciplinary task forces, psycho-oncology workforce development, and community-driven initiatives-is essential for improving post-treatment outcomes and advancing cancer survivorship care in SSA., (© 2025 John Wiley & Sons Ltd.)
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- 2025
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4. Home-based self-collection of biological samples, including vaginal swabs: a mixed methods study for Britain's fourth National Survey of Sexual Attitudes and Lifestyles (Natsal-4).
- Author
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Oeser C, Sonnenberg P, Unemo M, Sadler K, Clifton S, Gibbs J, Beddows S, Hamilton R, Roodt A, Migchelsen S, Dema E, David A, Mercer CH, and Field N
- Abstract
Objectives: The decennial National Surveys of Sexual Attitudes and Lifestyles (Natsal) provide general population prevalence estimates in Britain for key sexually transmitted infections (STIs) through biosampling. Since methodological choices can impact acceptability and response rates, we evaluated processes for Natsal-4, including face-to-face and remote interview arrangements, non-return of test results and vaginal swab collection in two pilot studies., Methods: The pilots were conducted during June to August 2021 and February to March 2022. Participants aged 16-59 years were invited to provide urine samples (cisgender men and trans/gender diverse) or three vaginal swabs (cisgender women; urine was requested if vaginal swabs were declined) following interview. Samples were self-collected at home and posted to the laboratory by the interviewer if the interview was face to face, or by the participant if they preferred to collect the sample later or the interview was remote. Process feedback was collected after the first pilot via qualitative interviews with participants and after both pilots through informal interviewer debriefing., Results: Of 261 participants interviewed (pilot 1=130; pilot 2=131), 161 (62%) consented to biosampling, of which 129 (49%) provided samples. A sample was received from 78/153 (51%) of women, of whom 60 (77%) provided vaginal swabs and 18 (23%) provided a urine sample. A urine sample was received from 51/108 (47%) cisgender men or trans/gender diverse participants. All samples collected immediately after face-to-face interviews were received (n=77), while 64% of samples from participants consenting to post samples after face-to-face interviews and 60% after remote interviews were received. Process feedback confirmed our methods were broadly acceptable., Conclusions: We demonstrated that our approach to biosampling and STI testing for a national sexual health survey was reasonably acceptable and feasible in the period coming out the COVID-19 pandemic. Self-collection of vaginal swabs for research, which provide higher testing sensitivity than urine, was feasible and acceptable in a home setting., Competing Interests: Competing interests: None declared., (© Author(s) (or their employer(s)) 2025. Re-use permitted under CC BY. Published by BMJ Group.)
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- 2025
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5. Perioperative Supportive Care Interventions to Enhance Surgical Outcomes for Older Adults With Cancer: A Systematic Review.
- Author
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Lam AB, Sorensen L, Moore VA, Bouvette MJ, Diaz Barba A, Clifton S, Wismann A, Keyser K, Shinall MC Jr, and Nipp RD
- Abstract
Purpose: Older adults with cancer have unique needs, which likely influence surgical outcomes in the geriatric oncology population. We conducted a systematic review to describe the literature focused on perioperative supportive care interventions for older adults with cancer undergoing surgery., Methods: Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, we performed a comprehensive search using the Ovid MEDLINE, CINAHL, and Embase databases for literature published from January 2010 to October 2023. We included randomized controlled trials (RCTs) focusing on supportive care interventions that enrolled adults older than 60 years with cancer., Results: We included 11 RCTs with 2,177 patients in this review. Patients' age ranged from 60 to 95, and the median number of patients per study was 147 (range, 44-690). Most studies included patients with colorectal cancer (81.8%). Half of the studies (54.5%) evaluated exercise interventions, and the remaining assessed geriatric assessment-guided interventions (27.2%), nutrition optimization (9.1%), and patient empowerment (9.1%). Primary outcomes included postoperative complications, quality of life, feasibility of exercise programs, inspiratory muscle endurance, and hospital length of stay, among others. All studies had postoperative complications as a primary or secondary outcome. We found implementation challenges that influenced several studies, including high dropout rates and intervention fidelity., Conclusion: We found 11 studies focused on perioperative supportive care interventions in older adults with cancer undergoing surgery. Notably, interventions involved exercise, geriatric assessment-guided care, nutrition optimization, and patient empowerment. We also found heterogeneity in intervention modality and outcome assessment, thus demonstrating a need for ongoing work to address the unique needs of the geriatric oncology population.
- Published
- 2025
- Full Text
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