Competing Interests: Conflicts of interest Dr Stratigos reports advisory board or steering committee roles for Janssen, Regeneron Pharmaceuticals, Inc, Roche, and Sanofi; and research support from AbbVie, Bristol Myers Squibb, LEO Pharma, Pfizer, Genesis Pharma, and Novartis. Dr Sekulic reports advisory roles for Regeneron Pharmaceuticals, Inc and Roche. Dr Peris reports advisory board roles for AbbVie, LEO Pharma, Janssen, Almirall, Eli Lilly, Galderma, Novartis, Pierre Fabre, Sun Pharma, and Sanofi, outside the submitted work. Dr Bechter reports advisory board roles for Novartis, Bristol Myers Squibb, Merck Sharp & Dohme, Pierre Fabre, and Ultimovacs. Dr Prey reports no conflict of interest. Dr Lewis reports grants and personal fees from Regeneron Pharmaceuticals, Inc, and is now an employee of Regeneron Pharmaceuticals, Inc. Dr Basset-Seguin is a consultant and investigator for Regeneron Pharmaceuticals, Inc, Sanofi, and Sun Pharma. Dr Chang reports advisory roles for Castle, Feldan, Merck, and Regeneron Pharmaceuticals, Inc; and research funding from Regeneron Pharmaceuticals, Inc, Merck, Novartis, and Galderma. Dr Dalle reports research grants and travel fees from Bristol Myers Squibb and Merck Sharp & Dohme; and reports that their spouse is an employee of Sanofi with stock options. Dr Fernández Orland declares no conflict of interest. Dr Licitra reports institutional grants and personal fees from AstraZeneca, Bristol Myers Squibb, Boehringer Ingelheim, Debiopharm International SA, Eisai, Novartis, and Roche; institutional grants from Celgene International, Exelixis, Hoffmann-La Roche, IRX Therapeutics, Medpace, Merck Serono, and Pfizer; and personal fees from Sobi, Ipsen, Incyte Biosciences Italy SRL, Doxa Pharma, Amgen, Nanobiotics SA, GSK, AccMed, Medical Science Foundation G. Lorenzini, Associazione Sinapsi, Think 2 IT, Aiom Servizi, Prime Oncology, WMA Congress Education, Fasi, DueCi Promotion SRL, MI&T, Net Congress & Education, PRMA Consulting, Kura Oncology, Health & Life SRL, and Immuno-Oncology Hub. Dr Robert reports grants, personal fees, and advisory board roles for Bristol Myers Squibb, Pierre Fabre, Novartis, Amgen, Merck, Roche, Merck Sharp & Dohme, Sanofi, Biothera, and Ultimovacs. Dr Ulrich reports advisory board and speaker roles for Roche, Sanofi, Regeneron Pharmaceuticals, and Sun Pharma. Dr Hauschild reports institutional funding and personal fees from Amgen, Bristol Myers Squibb, Merck Serono, Merck Sharp & Dohme, Merck & Co, Philogen, Pierre Fabre, Provectus, Regeneron Pharmaceuticals, Inc, Roche, Sanofi Genzyme, and Novartis; and consultancy fees from OncoSec, Almirall Hermal, and Sun Pharma. Dr Migden reports advisory roles for and travel fees from Regeneron Pharmaceuticals, Inc, and Sun Pharmaceuticals; an advisory role for Rakuten Medical; and research funding from Regeneron Pharmaceuticals, Inc, and PellePharm. Dr Dummer reports intermittent, project-focused consultant and advisory roles for Novartis, Merck Sharp & Dohme, Bristol Myers Squibb, Roche, Amgen, Takeda, Pierre Fabre, Sun Pharma, Sanofi, Catalym, Second Genome, Regeneron Pharmaceuticals, Inc, Alligator, MaxiVAX SA, and touchIME outside the submitted work. Drs Yoo, Inocencio, Chen, Seebach, Lowy, and Fury are employees and shareholders of Regeneron Pharmaceuticals, Inc. Mr Okoye is also an employee and shareholder of Regeneron Pharmaceuticals, Inc. Dr Bassukas reports non-financial support from Leo Pharma and Novartis, and institutional grants from Leo Pharma. Dr Loquai reports personal fees from Roche, Sun Pharma, Bristol Myers Squibb, Merck Sharp & Dohme, Merck, Novartis, Pierre Fabre, Kyowa Kirin, Almirall Hermal, and BioNTech. Dr De Giorgi reports no conflict of interest. Dr Eroglu reports advisory board fees from Regeneron Pharmaceuticals, Inc, Novartis, Pfizer, Genentech, Eisai, OncoSec, and Natera; and research grants from Novartis, Pfizer, and Boehringer Ingelheim. Dr Gutzmer reports documentation fees to their institution from Regeneron Pharmaceuticals, Inc; personal fees and non-financial support from Amgen, Bristol Myers Squibb, Roche Pharma, Merck Serono, Pierre Fabre, Sanofi, and Regeneron Pharmaceuticals, Inc; grants, personal fees, and non-financial support from Novartis; grants and personal fees from Pfizer; grants from Johnson & Johnson; and personal fees from Merck Sharp & Dohme, Almirall Hermal, Sun Pharma, 4SC, and Immunocore. Dr Ulrich reports grants and personal fees from Sanofi, Bristol Myers Squibb, Novartis, and Merck Sharp & Dohme; and personal fees from Roche, medac, and Sun Pharma. Dr Puig reports personal fees and non-financial support from Sanofi, Regeneron Pharmaceuticals, Inc, and Pfizer; grants from Avene; non-financial support from MAVIG, FotoFinder, 3Gen, AbbVie, Eli Lilly, and Merck Sharp & Dohme; grants, personal fees, and non-financial support from ISDIN, La Roche-Posay, and Roche; grants and personal fees from Sun Pharma, Leo Pharma, and Almirall; and personal fees from Ojer Pharma and Pierre Fabre. Dr LaFontaine reports employment at Sanofi and holds shares or stock in the company.