10 results on '"Chapman, Arlene B."'
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2. Temporal assessment of magnetic resonance imaging radiomic features to predict renal function decline in patients with autosomal dominant polycystic kidney disease
- Author
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Kremer, Linnea E., primary, Orlins, Maddie, additional, Trevino, John, additional, Fuhrman, Jordan D., additional, Chapman, Arlene B., additional, and Armato, Sam G., additional
- Published
- 2024
- Full Text
- View/download PDF
3. Circulating microRNA Biomarkers of Thiazide Response in Hypertension
- Author
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Chekka, Lakshmi Manasa S., primary, Tantawy, Marwa, additional, Langaee, Taimour, additional, Wang, Danxin, additional, Renne, Rolf, additional, Chapman, Arlene B., additional, Gums, John G., additional, Boerwinkle, Eric, additional, Cooper‐DeHoff, Rhonda M., additional, and Johnson, Julie A., additional
- Published
- 2024
- Full Text
- View/download PDF
4. Cardiac Localized Polycystin-2 plays a Functional Role in Natriuretic Peptide Production and its Absence Contributes to Hypertension
- Author
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Elliott, Brandon, primary, Márquez-Nogueras, Karla M., additional, Thuo, Paula, additional, DiNello, Elisabeth, additional, Knutila, Ryne M., additional, Fritzmann, Geena E., additional, Willis, Monte, additional, Chapman, Arlene B., additional, Cao, Quan, additional, Barefield, David Y., additional, and Kuo, Ivana Y., additional
- Published
- 2024
- Full Text
- View/download PDF
5. Contributors
- Author
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Abdelazeem, Mohamed A., Abelman, Rebecca A., Kar, Sarah Abu, Afari, Maxwell Eyram, Ahmad, Ali, Ahmed, Hammood, Ahn, Benjamin J., Ahn-Horst, Rosa, Akoto, Shanice, AlAbdulhadi, Abrar, Aldras, Yoseph A., Ali, Fahad, Ali, Tanya, Alipanah-Lechner, Narges, Altunel, Erdem, Alzoebie, Lama, Anderson, Chelsie, Andrews, Christine B., Taylor, Kathryn Maire, Anthony, Anngene, Asaro, Joseph A., Asiedu, Daniel K., Astsaturov, Artem, Aulakh, Sudeep K., Authement, Matthew, Avasare, Rupali S., Babar, Tania B., Bachman, Emelia Argyropoulos, Baig, Muhammad, Bains, Ashika, Balaguera, Pedro, Balda, Javier, Bank, T. Caroline, Banwell, Brenda, Basman, Craig L., Bass, Crystal T., Bayefsky, Sarah D., Beausang, Jasjit, Belcher, Ren, Bell, Jennifer, Bellinghausen, Amy L., Bennett, Colleen E., Benninger, John W., Bergen, Michael A., Berger, Agatha, Berkowitz, Carol D., Berkowitz, Julia, Betageri, Omkar, Bhagat, Vicky H., Bharmal, Murtaza, Bhatt, Harikrashna B., Bhuptani, Prachi H., Bido-Medina, Richard O., Bielak, Kendall M.H., Bilodeau, Courtney Clark, Bird, Lisa, Bishop, Erin, Bitar, Ghamar, Blakeney, Craig, Block, Brian, Bochner, Risa, Bortz, Christina M., Bosse, Kristopher R., Bouton, Tara C., Bove, Mary E., Bowlby, Lynn A., Brady, Mark F., Bratman, Russell E., Brennan, Keith, Brown, Austin K., Brown, Emily C.B., Bui, Eric, Burke, Christine, Butler, William, Byanova, Katerina L., Byra, Marcin, Callanan, Tucker C., Campbell, Taylor, Cantos, Adriana, Canty, Ethan, Canty, Katherine W., Caraganis, Andrew, Carpenter, Randy S., Carragee, Eugene, Carrel-Lammert, Meredith, Carter, Ashlie Sewdass, Casillas, Ernesto, Jr., Castaneda-Guarderas, Ana, Castillo, Jorge J., Chait, Daniel, Chan, Philip A., Chang, Kenny, Chapman, Arlene B., Chatterjee-Paer, Sudeshna, Chaudhary, Richard S., Cheng, Vicky, Chilcote, Daniel, Chofay, Dana Ricci, Chou, Jonathan, Chou, Stella T., Choudhury, Natasha, Choxi, Shivali, Chua, Winona, Chubb, Rhiannon E., Cinelli, Michael P., Claman, David, Clark, Grace V., Clark, Seth, Clarke, Nathan, Clebak, Karl T., Cleland, Derrick, Co, Michael Lawrenz, Cohen, Debbie L., Cohen, Lisa, Congdon, Morgan, Constantinou, Maria, Corley, James Earl, III, Cosgrove, Abigail, Craine, Rebecca, Cristofaro, Patricia, Cruz, Aristides I., Cunningham, Karlene, Curtin, Alicia J., Cusano, Joseph, D’Alessandro, Frank B., Dado, Lynn, Dalela, Deepansh, Das, Abhijit, DaSilva, Manuel F., Davis, Mackenzie, De La Garza, Carlos, DeDent, Alison, Deeb, Maya, DeJong, Tyler, Desrochers, Colette, Diaz, Joseph A., Dickherber, Jason L., Do, Toan, Doo, Kathleen, Dove, James H., Dubanchet, Alexandre, Duh-Leong, Carol, Dutta, Roop, Dworkin, Myles, Dyster, Timothy G., Ebert, Eric, Edmund, Joseph, Eggers, Erica, Eisenhower, Christine, Ellsworth, Pamela, Escamilla-Ocañas, César E., Espinosa, Patricio Sebastian, Esqueda, Marisol, Everly, Eileen, Faber, Mark D., Faber, Rachel, Facer, Evan, Fadale, Paul D., Farahvash, Benyamin, Farias, Michael J., Farkas, Jon, Farrand, Erica, Fay, Kevin, Hernandez, Samantha Fernandez, Fernandez-Robles, Carlos, Ferreira, Jason D., Ferri, Fred F., Ferri, Heather, Fischer, Staci A., Fiske, Hannah, Velez Florez, Maria Camila, Font, Cristina, Forbes, Kellie C., Forcier, Michelle, Ford, Sydney, Fort, Frank G., Fort, Glenn G., Freeman, Nancy, Frisch, Daniel R., Fru, Relindis Azenwi, Fullenkamp, Lynn C., Gaffney, Michael, Garcia, Paloma Jolin, Ge, Connie, Gesthalter, Yaron B., Ghimire, Anil, Gibson, Christopher, Gidwani, Nisha H., Gil, Joseph, Gold, Raphaela, Goldburt, Alla, Goldsmith, Corey Elam, Gangadhara Rao Golla, Maheswara Satya, Gomez, Alexander, Gomez Slagle, Helen B., Greenfield, Morgan, Grisham, Lindsey Anne, Gu, Joey, Guardino, Cara E., Gugerty, Lindsay, Gul, Fahad, Gultawatvichai, Patan, Gunning, Samantha, Guo, Averill, Guo, David, Gupta, Simran, Guttadauria, Brittany, Guzman, Herodes, Gwinn, Meghan, Hadden, Ryan, Hafeez, Muhammad Ubaid, Hall, Hayden, Hall, Sarah, Handa, Sajeev, Handler, Stacy N., Hanna, James, Hanna, John, Harbord, Nikolas, Hardacker, Kyle, Hardesty, Anna, Haribhakti, Nirav, Harris, Daniel J., Hartnett, Davis A., Hartvigsen, Nathan, Hawkins, Brian, Heinle, Rachel Wright, Helm, Leesha A., Helm, Matthew F., Herlevich, Thomas, Hermez, Klodia M., Hilliard, Ross W., Hladky, Katherine, Hodges, Ashley, Hoffman, Ryan, Hoffman, R. Scott, Hogan, Dawn, Holiman, Jennifer J., Holland, N. Wilson, Holton, Siri M., Homer, Benjamin J., Hook, Benjamin E., Howell, Cody, Hsu, Raymond, Huang, Laurence, Hull, Mariam, Hume, Anne L., Hussain, Zilla, Huynh, Donny V., Hyder, Sarah, Ibrahim, Zainab, Ingraham, Caitlin, Inman, Nicholas J., Insalaco, Louis F., Jain, Rishubh, Jain, Vanita B.D., Jain, Vipul V., Jamal, Fariha, Jani, Kaushal, Janigian, Robert H., Jr., Jasuja, Sonia, Javier, Noelle Marie, Jetty, Vybhav, Johnson, Jennie E., Johnson, Michael P., Johnson, Steven D., Jolly, Angad, Jones, Amanda, Joshi, Shyam, Joudi, Kareem, Justice, Joshua, Kaddis, Timothy, Kalligeros, Markos, Karim, Omar, Karthikeyan, Vanji, Kartub, Benjamin, Kasper, Vania, Kass, Joseph S., Kass, Naomi R., Kasthuri, Viknesh S., Katz, Luca, Kaul, Bhavika, Kaur, Arpanjeet, Keim, Jennifer L., Keleshian, Vasken, Keogh, Abigail, Keselman, Dennis, Khan, Adeeba, Khare, Sarthak, Khawaja, Hussain R., Khetpal, Vishal, Khurana, Saranya S., Kifle, Betelhem, Kyung (Ellen) Kim, Eun, Kim, Jinseong, Kleitsch, Julianne, Knudson-Fitzpatrick, Tess, Kohrman, Samuel I., Kokkirala, Aravind Rao, Konstantino, Yuval, Kopyt, Nelson, Kothadia, Savan, Koti, Ajay, Koulouridis, Ioannis, Kreider, Timothy R., Krueger, Van S., Krumm, Ilana, Kumbar, Lalathaksha, Kuris, Eren O., Kurss, David I., L’Etoile, Nathan, Lam, Uyen T., Lam, William, Larijani, Mary, Le, Peter, Leard, Lorriana E., Leavitt, David A., Leba, Christopher T., Lee, Kachiu C., Lemme, Nicholas J., Li, Jian, Lieberman, Leora, Lim, Carol, Lin, Jason, Lippincott, Jordan, Liu, Jonathan, Logue, Teresa C., López, Gabriela, Lord, Kito Akin, Lucas, Mathew J., Lucier, David J., Jr., Ma’ayeh, Marwan, Maclean, Rachel L., MacMurdo, Maeve G., Madva, Elizabeth N., Mahani, Sahar, Makai, Gretchen, Malpica, Luis, Marcaccio, Stephen E., Marques Pinheiro, Ana Paula, Mazzaglia, Peter J., Mbuyi, Nadine N., McCulloh, Russell J., McDonald, Christopher L., McDonald-McGinn, Donna M., McGowen, Alexandra, McGraw, Katherine Elizabeth, McKenna, Jaclyn, McNamara, Kelly, Mead, Kelly C., Meehan, Caroline P., Meghani, Ozair K., Meleveedu, Kapil S., Mendez, Dianelys, Mendez-Miller, Megan, Mercado, Jorge, Mercado, Osvaldo, Merrill, Scott J., Merritt, Rory, Michaels, Marian G., Michel, Jeremy, Mikolasko, Brian D., Milner, John D., Min, May, Minami, Taro, Mitsuyama, Rei, Miyares, Laura, Mogla, Ankur, Mojarrab, Javad Najjar, Montgrain, Philippe, Moore, Michael Z., Moore, Shawn D., Morelli, Leah, Morrissey, Patrick J., Mughal, Aleem I., Mukkamalla, Shiva Kumar R., Mullersman, Katherine M., Mumtaz, Ahmad, Muraina, Fadeke, Mustafa, Ahmad, Myers, Ellen, Mylhousen, Emily, Nadella, Akash, Nadella, Mohnish, Nagpal, Nikita, Nandi, Minesh, Nasir, Uzma, Nasr, George H., Naveed, Asim, Neff, Robert, Neithardt, Adrienne B., Nelin, Timothy, Nestlerode, Christina, Ni, Samantha, Niazi, Azfar K., Nichols, Jonathan, Nokoff, Natalie, Noorbhai, Ibrahim Z.D., Novak, James E., Novarra, Austin, Nuss, Emily E., Oliver, Rebecca, Olszewski, Adam J., Onyeaka, Henry K., Orchowski, Lindsay M., Outlaw, Jasmine, Owens, Brett D., Oyelakin, Ayotomide, Pace, Paolo G., Palma-Zamora, Isaac, Pandya, Rachita, Pappas-Taffer, Lisa, Paranandi, Sneha, Parikh, Mihir, Park, Sara, Partin, Michael T., Patel, Birju B., Patel, Melissa D., Patel, Minta, Patel, Nima R., Patel, Pranav M., Patel, Vidhi, Patrick, Brett, Paudel, Shreedhar, Paxton, E. Scott, Peay, Celeste, Perazella, Mark A., Perez, David L., Hermina Perez, Jose J., Devon, Erin Pete, Pfeuti, Courtney, Pham, Lily C., Phelps-Polirer, Kendall, Phillips, Katharine A., Phillips, Oliver W., Phillips, Tara M., Piana, Lauren E., Portnoff, Brandon, Powell, Mitchell, Powers, Alexander, Prashar, Rohini, Premyodhin, Ned, Price, Dana, Priestley, Margaret, Provenza, Christian, Pulice, Christine, Punko, Diana, Puthawala, Imran, Qawi, Imrana, Qu, David, Quesada, Adrian, Quinn, Matthew, Rachu, Gregory S., Rajagopal, Amulya, Rathore, Bharti, Rathore, Ritesh, Raukar, Neha P., Ravindra, Lakshmi, Reagan, John L., Reardon, P.K., Reddy, Bharathi V., Reddy, Snigdha T., Reed-Weston, Anne, Reginato, Anthony M., Reichart, James P., Reus, Victor I., Rich, Harlan G., Rivera, Lauren Davis, Robertson, Melena J., Roby, Lauren, Roche, Meaghan, Morfin Rodriguez, Alejandra E., Romero Gómez, Perla M., Ron, Hayley A., Rosenbaum, Blake L., Rossi, Michael, Roussel, Breton, Rubin, David, Ruhstaller, Kelly, Rutstein, Beth H., Sadeghi, Noushine, Sahota, Ruchi Jalota, Saks, Emily, Sall, Jeffrey W., Salvi, Joshua D., Sanchez, Frank, Sanchez, Martha C., Sanka, Pranavi, Santhosh, Lekshmi, Santos, Linda Herrera, Sauck, Emily, Sayeed, Syeda M., Saylor, Leah, Schmitt, Phillip R., Sciscione, Anthony, Sederdahl, Bethany K., Seeber, Richard E., II, Sen, Aritra, Sewell, Rachel, Shaban, Hesham, Shah, Ankur, Shaikh, Aaron Ali, Sharma, Animesh, Sharma, Yuvraj, Sharp, Lydia, Sheikh, Wasiq, Sherman, Alexander, Shill, Jessica E., Shimanovsky, Alexei, Shlossman, Philip A., Siddiqui, Khawja A., Siegel, Alyssa, Sigman, Mark, Simon, Rebecca, Singh, Harinder P., Slingsby, Brett, Sloane, Amy, Smick, Alexandra H., Smith, Devon, Smith, Jeanette G., Smith, Matthew J., Sohaney, Ryann, Soi, Vivek, Soinski, Rebecca, Soler, Maria E., Soman, Sandeep, Song, Jeffrey S., Sorg, Emily, Sperati, C. John, Stanford, Nathan, Stennis, Seth Daly, Stephens, Michael S., Stern, Ella, Stockwell, Philip, Suh, Edward, Sun, Jennifer K., Sundaramoorthy, Anjali, Supanakorn, Varut, Suri, Priyasha, Sutter, Stephanie, Sweeney, Hannah, Takasaki, Kaoru, Takei, Ryosuke, Tan, Laren, Taylor, Alan, Taylor, Matthew, Taylor, S. Trevor, Tellioglu, Tahir, Testa, Edward J., Thomas, Anthony G., Thompson, Stefani, Tien, Alexandra Meyer, Tien, David Robbins, Tierney, Anna-Marie, Tiffany, Patrick, Toma, Helen, Triplett, Thomas M., Tryforos, Margaret, Tsaban, Gal, Tschoe, Christine, Tucci, Joseph R., Turock, Julia, Uduman, Junior, Uiterwyk, Sean H., Ukaegbu, Rebecca, Umanath, Kausik, Vakili, Babak, Van Kirk, Emily, Vemula, Ridhima, Venado, Aida, Vijayakumar, Shilpa, Vollum, Kathryn G., Vorel, Ethan, Walson, Ifeanyi, Wang, Angela, Wang, Jarey H., Weekley, Manuel Shayne, Weinberg, Marc S., Wendolowski, Stephen, Westreich, Roi, Whitaker, Colin, Wilhoite, Morgan, Wilks, Andrew, Wilson, Annise, Winikor, Jared M., Wininger, Bryce, Winschel, Julia M., Wolpaw, Adam J., Wolpert, Marlene Fishman, Wu, Perry, Wylie, John, Yaguchi, Grace K., Yang, Anna, Yao, Xuan, Yaseen, Muhammad, Yee, Jerry, Yesodharan, Gemini, Yeung, Jennifer, Yin, Chun H., Yip, Agustin G., Yu, Elizabeth An, Zambrano, Juliana, Zenlea, Talia, Zha, B. Shoshana, Zhang, Helen, Zhao, Leon, Zhou, Diana X., Ziaie, Navid, Zollman, Joshua W., Zorin, Danylo, and Zurek, Olivia
- Published
- 2024
- Full Text
- View/download PDF
6. Temporal assessment of magnetic resonance imaging radiomic features to predict renal function decline in patients with autosomal dominant polycystic kidney disease
- Author
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Chen, Weijie, Astley, Susan M., Kremer, Linnea E., Orlins, Madison, Trevino, John M., Fuhrman, Jordan D., Chapman, Arlene B., and Armato, Sam G.
- Published
- 2024
- Full Text
- View/download PDF
7. In memoriam: George L. Bakris, MD 1952 - 2024
- Author
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Chapman, Arlene B., Rafey, Mohammad A., Chertow, Glenn M., and Weir, Matthew
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- 2024
- Full Text
- View/download PDF
8. Cardiac Localized Polycystin-2 in the Natriuretic Peptide Signaling Pathway and Hypertension.
- Author
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Márquez-Nogueras KM, Elliott B, Thuo P, DiNello E, Knutila RM, Fritzmann GE, Vuchkovska V, Flury S, Willis M, Chapman AB, Cao Q, Barefield DY, and Kuo IY
- Abstract
Background: Hypertension is seen in 70% of autosomal dominant polycystic kidney disease (ADPKD) patients by the age of 30 prior to decline in kidney function. However, cardiac origins of hypertension, such as the natriuretic peptide signaling pathway, have not been fully investigated. We hypothesized that cardiomyocyte-localized polycystin proteins contribute to production of natriuretic peptides, and loss of this pathway would contribute to hypertension., Methods: Telemetry, echocardiography, and a molecular analysis of the natriuretic peptide pathway from left-ventricular tissue of cardiomyocyte-specific knock-out models of polycystin-2 (cPC2-KO) mice and Cre control littermates was conducted. Complementary studies were conducted in ex-vivo murine hearts, engineered heart tissue with human iPSCs driven into cardiomyocytes with CRISPR/Cas9 KO of PKD2 and in in-vitro cell lines., Results: cPC2-KO mice demonstrated diurnal hypertension. Circulating ANP and BNP were unchanged between cPC2-KO and Cre mice. Analysis of the pathways involved in production, maturation, and activity of natriuretic peptides identified decreased transcription of CgB, PCSK6, NPR1 and NFAT genes in cPC2-KOs. Human iPSC-derived cardiomyocytes with PC2-KO failed to produce ANP. Re-expression of polycystin-2 in a myoblast cell line, but not pathogenic forms of polycystin-2, restored ANP production., Conclusions: Natriuretic peptide production required cardiac localized polycystin-2 and loss of this pathway may contribute to the development of hypertension in ADPKD., (Copyright © 2024 by the American Society of Nephrology.)
- Published
- 2024
- Full Text
- View/download PDF
9. All Patients with ADPKD Should Undergo Screening for Intracranial Aneurysms: COMMENTARY.
- Author
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Chapman AB
- Subjects
- Humans, Mass Screening methods, Intracranial Aneurysm diagnosis, Intracranial Aneurysm epidemiology, Polycystic Kidney, Autosomal Dominant diagnosis, Polycystic Kidney, Autosomal Dominant epidemiology
- Published
- 2024
- Full Text
- View/download PDF
10. Cardiac Localized Polycystin-2 plays a Functional Role in Natriuretic Peptide Production and its Absence Contributes to Hypertension.
- Author
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Elliott B, Márquez-Nogueras KM, Thuo P, DiNello E, Knutila RM, Fritzmann GE, Willis M, Chapman AB, Cao Q, Barefield DY, and Kuo IY
- Abstract
Cardiovascular complications are the most common cause of mortality in patients with autosomal dominant polycystic kidney disease (ADPKD). Hypertension is seen in 70% of patients by the age of 30 prior to decline in kidney function. The natriuretic peptides (NPs), atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP), are released by cardiomyocytes in response to membrane stretch, increasing urinary excretion of sodium and water. Mice heterozygous for Pkd2 have attenuated NP responses and we hypothesized that cardiomyocyte-localized polycystin proteins contribute to production of NPs. Cardiomyocyte-specific knock-out models of polycystin-2 (PC2), one of the causative genes of ADPKD, demonstrate diurnal hypertension. These mice have decreased ANP and BNP expression in the left ventricle. Analysis of the pathways involved in production, maturation, and activity of NPs identified decreased transcription of CgB, PCSK6, and NFAT genes in cPC2-KOs. Engineered heart tissue with human iPSCs driven into cardiomyocytes with CRISPR/Cas9 KO of PKD2 failed to produce ANP. These results suggest that PC2 in cardiomyocytes are involved in NP production and lack of cardiac PC2 predisposes to a hypertensive volume expanded phenotype, which may contribute to the development of hypertension in ADPKD.
- Published
- 2024
- Full Text
- View/download PDF
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