Search

Your search keyword '"Bartley, A."' showing total 358 results
Start Over Author "Bartley, A." Publication Year Range This year
358 results on '"Bartley, A."'

1. Cryogenic Feedforward of a Photonic Quantum State

Author

Thiele, Frederik, Lamberty, Niklas, Hummel, Thomas, Lange, Nina A., Procopio, Lorenzo M., Barua, Aishi, Lengeling, Sebastian, Quiring, Viktor, Eigner, Christof, Silberhorn, Christine, and Bartley, Tim J.

Subjects
Quantum Physics, Physics - Optics
Abstract

Modulation conditioned on measurements on entangled photonic quantum states is a cornerstone technology of optical quantum information processing. Performing this task with low latency requires combining single-photon-level detectors with both electronic logic processing and optical modulation in close proximity. In the technologically relevant telecom wavelength band, detection of photonic quantum states is best performed with high-efficiency, low-noise, and high-speed detectors based on the photon-induced breakdown of superconductivity. Therefore, using these devices for feedforward requires mutual compatibility of all components under cryogenic conditions. Here, we demonstrate low-latency feedforward using a quasi-photon-number-resolved measurement on a quantum light source. Specifically, we use a multipixel superconducting nanowire single-photon detector, amplifier, logic, and an integrated electro-optic modulator in situ below 4K. We modulate the signal mode of a spontaneous parametric down-conversion source, conditional on a photon-number measurement of the idler mode, with a total latency of (23+/-3)ns. The photon-number discrimination actively manipulates the signal mode photon statistics, which is itself a central component in photonic quantum computing reliant on heralded single-photon sources. This represents an important benchmark for the fastest quantum photonic feedforward experiments comprising measurement, amplification, logic and modulation. This has direct applications in quantum computing, communication, and simulation protocols.

Published
2024

2. Three-in-One: Fast and Accurate Transducer for Hybrid-Autoregressive ASR

Author

Xu, Hainan, Bartley, Travis M., Bataev, Vladimir, and Ginsburg, Boris

Subjects
Computer Science - Machine Learning
Abstract

We present \textbf{H}ybrid-\textbf{A}utoregressive \textbf{IN}ference Tr\textbf{AN}sducers (HAINAN), a novel architecture for speech recognition that extends the Token-and-Duration Transducer (TDT) model. Trained with randomly masked predictor network outputs, HAINAN supports both autoregressive inference with all network components and non-autoregressive inference without the predictor. Additionally, we propose a novel semi-autoregressive inference paradigm that first generates an initial hypothesis using non-autoregressive inference, followed by refinement steps where each token prediction is regenerated using parallelized autoregression on the initial hypothesis. Experiments on multiple datasets across different languages demonstrate that HAINAN achieves efficiency parity with CTC in non-autoregressive mode and with TDT in autoregressive mode. In terms of accuracy, autoregressive HAINAN outperforms TDT and RNN-T, while non-autoregressive HAINAN significantly outperforms CTC. Semi-autoregressive inference further enhances the model's accuracy with minimal computational overhead, and even outperforms TDT results in some cases. These results highlight HAINAN's flexibility in balancing accuracy and speed, positioning it as a strong candidate for real-world speech recognition applications.

Published
2024

3. Bias Reduction in Social Networks through Agent-Based Simulations

Author

Bartley, Nathan, Burghardt, Keith, and Lerman, Kristina

Subjects
Computer Science - Social and Information Networks, Computer Science - Computers and Society
Abstract

Online social networks use recommender systems to suggest relevant information to their users in the form of personalized timelines. Studying how these systems expose people to information at scale is difficult to do as one cannot assume each user is subject to the same timeline condition and building appropriate evaluation infrastructure is costly. We show that a simple agent-based model where users have fixed preferences affords us the ability to compare different recommender systems (and thus different personalized timelines) in their ability to skew users' perception of their network. Importantly, we show that a simple greedy algorithm that constructs a feed based on network properties reduces such perception biases comparable to a random feed. This underscores the influence network structure has in determining the effectiveness of recommender systems in the social network context and offers a tool for mitigating perception biases through algorithmic feed construction.

Published
2024

4. RTs != Endorsements: Rethinking Exposure Fairness on Social Media Platforms

Author

Bartley, Nathan and Lerman, Kristina

Subjects
Computer Science - Social and Information Networks
Abstract

Recommender systems underpin many of the personalized services in the online information & social media ecosystem. However, the assumptions in the research on content recommendations in domains like search, video, and music are often applied wholesale to domains that require a better understanding of why and how users interact with the systems. In this position paper we focus on social media and argue that personalized timelines have an added layer of complexity that is derived from the social nature of the platform itself. In particular, definitions of exposure fairness should be expanded to consider the social environment each user is situated in: how often a user is exposed to others is as important as who they get exposed to.

Published
2024

5. Longer is (Not Necessarily) Stronger: Punctuated Long-Sequence Training for Enhanced Speech Recognition and Translation

Author

Koluguri, Nithin Rao, Bartley, Travis, Xu, Hainan, Hrinchuk, Oleksii, Balam, Jagadeesh, Ginsburg, Boris, and Kucsko, Georg

Subjects
Electrical Engineering and Systems Science - Audio and Speech Processing, Computer Science - Computation and Language
Abstract

This paper presents a new method for training sequence-to-sequence models for speech recognition and translation tasks. Instead of the traditional approach of training models on short segments containing only lowercase or partial punctuation and capitalization (PnC) sentences, we propose training on longer utterances that include complete sentences with proper punctuation and capitalization. We achieve this by using the FastConformer architecture which allows training 1 Billion parameter models with sequences up to 60 seconds long with full attention. However, while training with PnC enhances the overall performance, we observed that accuracy plateaus when training on sequences longer than 40 seconds across various evaluation settings. Our proposed method significantly improves punctuation and capitalization accuracy, showing a 25% relative word error rate (WER) improvement on the Earnings-21 and Earnings-22 benchmarks. Additionally, training on longer audio segments increases the overall model accuracy across speech recognition and translation benchmarks. The model weights and training code are open-sourced though NVIDIA NeMo., Comment: Accepted at SLT 2024

Published
2024

6. Context-Dependent Social Comparison and Imposter Phenomenon: An Experimental Vignette Approach

Author

Kate E. Snyder, Maxwell I. Bartley, and Allison Fowler

Abstract

Recent research into imposter phenomenon, or internal feelings of questioning competence, has shifted away from conceptualizing the feeling as an individual characteristic that requires an individual solution toward instead examining the role of context. We used a 2 (Generational Status: First Generation vs. Continuing Generation) × 3 (Environment: Classroom vs. Peer vs. Administration) × 2 (Social Comparison: Present vs. Absent) experimental vignette design. Overall, we found that, for both first- and continuing-generation students, social comparison messages differentially impacted imposter feelings depending on context, with the most elevated levels in social comparison messages from administrators and peers. Findings contribute to a better understanding of structural conditions that exacerbate or lessen imposter feelings at highly selective post-secondary institutions.

Published
2024
Full Text
View/download PDF

7. Transcobalamin receptor antibodies in autoimmune vitamin B12 central deficiency

Author

Pluvinage, John V, Ngo, Thomas, Fouassier, Camille, McDonagh, Maura, Holmes, Brandon B, Bartley, Christopher M, Kondapavulur, Sravani, Hurabielle, Charlotte, Bodansky, Aaron, Pai, Vincent, Hinman, Sam, Aslanpour, Ava, Alvarenga, Bonny D, Zorn, Kelsey C, Zamecnik, Colin, McCann, Adrian, Asencor, Andoni I, Huynh, Trung, Browne, Weston, Tubati, Asritha, Haney, Michael S, Douglas, Vanja C, Louine, Martineau, Cree, Bruce AC, Hauser, Stephen L, Seeley, William, Baranzini, Sergio E, Wells, James A, Spudich, Serena, Farhadian, Shelli, Ramachandran, Prashanth S, Gillum, Leslie, Hales, Chadwick M, Zikherman, Julie, Anderson, Mark S, Yazdany, Jinoos, Smith, Bryan, Nath, Avindra, Suh, Gina, Flanagan, Eoin P, Green, Ari J, Green, Ralph, Gelfand, Jeffrey M, DeRisi, Joseph L, Pleasure, Samuel J, and Wilson, Michael R

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Women's Health, Autoimmune Disease, Brain Disorders, Dietary Supplements, Nutrition, Clinical Research, Minority Health, Neurosciences, Biotechnology, 2.1 Biological and endogenous factors, Neurological, Humans, Vitamin B 12 Deficiency, Vitamin B 12, Autoantibodies, Female, Receptors, Cell Surface, Antigens, CD, Middle Aged, Autoimmune Diseases, Blood-Brain Barrier, Male, Biological Sciences, Medical and Health Sciences, Medical biotechnology, Biomedical engineering
Abstract

Vitamin B12 is critical for hematopoiesis and myelination. Deficiency can cause neurologic deficits including loss of coordination and cognitive decline. However, diagnosis relies on measurement of vitamin B12 in the blood, which may not accurately reflect the concentration in the brain. Using programmable phage display, we identified an autoantibody targeting the transcobalamin receptor (CD320) in a patient with progressive tremor, ataxia, and scanning speech. Anti-CD320 impaired cellular uptake of cobalamin (B12) in vitro by depleting its target from the cell surface. Despite a normal serum concentration, B12 was nearly undetectable in her cerebrospinal fluid (CSF). Immunosuppressive treatment and high-dose systemic B12 supplementation were associated with increased B12 in the CSF and clinical improvement. Optofluidic screening enabled isolation of a patient-derived monoclonal antibody that impaired B12 transport across an in vitro model of the blood-brain barrier (BBB). Autoantibodies targeting the same epitope of CD320 were identified in seven other patients with neurologic deficits of unknown etiology, 6% of healthy controls, and 21.4% of a cohort of patients with neuropsychiatric lupus. In 132 paired serum and CSF samples, detection of anti-CD320 in the blood predicted B12 deficiency in the brain. However, these individuals did not display any hematologic signs of B12 deficiency despite systemic CD320 impairment. Using a genome-wide CRISPR screen, we found that the low-density lipoprotein receptor serves as an alternative B12 uptake pathway in hematopoietic cells. These findings dissect the tissue specificity of B12 transport and elucidate an autoimmune neurologic condition that may be amenable to immunomodulatory treatment and nutritional supplementation.

Published
2024

8. Scalable quantum detector tomography by high-performance computing

Author

Schapeler, Timon, Schade, Robert, Lass, Michael, Plessl, Christian, and Bartley, Tim J.

Subjects
Quantum Physics, Computer Science - Distributed, Parallel, and Cluster Computing
Abstract

At large scales, quantum systems may become advantageous over their classical counterparts at performing certain tasks. Developing tools to analyse these systems at the relevant scales, in a manner consistent with quantum mechanics, is therefore critical to benchmarking performance and characterising their operation. While classical computational approaches cannot perform like-for-like computations of quantum systems beyond a certain scale, classical high-performance computing (HPC) may nevertheless be useful for precisely these characterisation and certification tasks. By developing open-source customised algorithms using high-performance computing, we perform quantum tomography on a megascale quantum photonic detector covering a Hilbert space of $10^6$. This requires finding $10^8$ elements of the matrix corresponding to the positive operator valued measure (POVM), the quantum description of the detector, and is achieved in minutes of computation time. Moreover, by exploiting the structure of the problem, we achieve highly efficient parallel scaling, paving the way for quantum objects up to a system size of $10^{12}$ elements to be reconstructed using this method. In general, this shows that a consistent quantum mechanical description of quantum phenomena is applicable at everyday scales. More concretely, this enables the reconstruction of large-scale quantum sources, processes and detectors used in computation and sampling tasks, which may be necessary to prove their nonclassical character or quantum computational advantage., Comment: 31 pages, 8 figures

Published
2024

9. Optical Bias and Cryogenic Laser Readout of a Multipixel Superconducting Nanowire Single Photon Detector

Author

Thiele, Frederik, Lamberty, Niklas, Hummel, Thomas, and Bartley, Tim

Subjects
Physics - Optics, Physics - Applied Physics, Quantum Physics
Abstract

Cryogenic opto-electronic interconnects are gaining increasing interest as a means to control and read out cryogenic electronic components. The challenge is to achieve sufficient signal integrity with low heat load processing. In this context, we demonstrate the opto-electronic bias and readout of a commercial four-pixel superconducting nanowire single-photon detector array using a cryogenic photodiode and laser. We show that this approach has a similar system detection efficiency to a conventional bias. Furthermore, multi-pixel detection events are faithfully converted between the optical and electrical domain, which allows reliable extraction of amplitude multiplexed photon statistics. Our device has a passive heat dissipation of 2.6mW, maintains the signal rise time of 3ns, and operates in free-running (self-resetting) mode at a repetition rate of 600kHz. This demonstrates the potential of high-bandwidth, low noise, and low heat load opto-electronic interconnects for scalable cryogenic signal processing and transmission.

Published
2024

10. Characterization and visualization of tandem repeats at genome scale

Author

Dolzhenko, Egor, English, Adam, Dashnow, Harriet, De Sena Brandine, Guilherme, Mokveld, Tom, Rowell, William J., Karniski, Caitlin, Kronenberg, Zev, Danzi, Matt C., Cheung, Warren A., Bi, Chengpeng, Farrow, Emily, Wenger, Aaron, Chua, Khi Pin, Martínez-Cerdeño, Verónica, Bartley, Trevor D., Jin, Peng, Nelson, David L., Zuchner, Stephan, Pastinen, Tomi, Quinlan, Aaron R., Sedlazeck, Fritz J., and Eberle, Michael A.

Published
2024
Full Text
View/download PDF

11. Anti-RGS8 paraneoplastic cerebellar ataxia is preferentially associated with a particular subtype of Hodgkin’s lymphoma

Author

Peter, Elise, Ciano-Petersen, Nicolas Lundahl, Do, Le-Duy, Perrot, Jimmy, Ngo, Thomas, Pluvinage, John, Bartley, Christopher M., Zorn, Kelsey C., Miske, Ramona, Scharf, Madeleine, Villagrán-García, Macarena, Farina, Antonio, Rogemond, Véronique, Antoine, Jean-Christophe, Tranchant, Christine, Dubois, Valérie, DeRisi, Joseph L., Pleasure, Samuel J., Wilson, Michael R., Gelfand, Jeffrey M., Traverse-Glehen, Alexandra, Honnorat, Jérôme, and Desestret, Virginie

Published
2024
Full Text
View/download PDF

14. An autoantibody signature predictive for multiple sclerosis

Author

Zamecnik, Colin R., Sowa, Gavin M., Abdelhak, Ahmed, Dandekar, Ravi, Bair, Rebecca D., Wade, Kristen J., Bartley, Christopher M., Kizer, Kerry, Augusto, Danillo G., Tubati, Asritha, Gomez, Refujia, Fouassier, Camille, Gerungan, Chloe, Caspar, Colette M., Alexander, Jessica, Wapniarski, Anne E., Loudermilk, Rita P., Eggers, Erica L., Zorn, Kelsey C., Ananth, Kirtana, Jabassini, Nora, Mann, Sabrina A., Ragan, Nicholas R., Santaniello, Adam, Henry, Roland G., Baranzini, Sergio E., Zamvil, Scott S., Sabatino, Jr., Joseph J., Bove, Riley M., Guo, Chu-Yueh, Gelfand, Jeffrey M., Cuneo, Richard, von Büdingen, H.-Christian, Oksenberg, Jorge R., Cree, Bruce A. C., Hollenbach, Jill A., Green, Ari J., Hauser, Stephen L., Wallin, Mitchell T., DeRisi, Joseph L., and Wilson, Michael R.

Published
2024
Full Text
View/download PDF

17. Editorial: Women in aging and the immune system

Author

Bartley, Jenna M and Agrawal, Anshu

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, aging, immune dysfunction, inflammaging, metformin, senolytic, Clinical sciences
Published
2024

19. Response to comment by Daley et al., on 'Assessing gully erosion and rehabilitation using multi temporal LiDAR DEMs: Case study from the Great Barrier Reef catchments, Australia'

Author

Sana Khan, Rebecca Bartley, Anne Kinsey-Henderson, and Aaron Hawdon

Subjects
Digital elevation models, (dis)connectivity, Restoration, Geomorphic change detection, Geomorphic effectiveness, GIS, Engineering (General). Civil engineering (General), TA1-2040
Abstract

Daley et al. (2023a) argue that at least 10–15 years apart Digital Elevation Model (DEM) derived DEMs of Difference (DoD) surveys are needed to detect reliable geomorphic change within the gullied landscapes of the Great Barrier Reef, Australia. We acknowledge that the reliability of observed geomorphic change increases as more subtle geomorphic processes are detected with longer monitoring periods. As further good quality long-term legacy datasets become available, we encourage utilising these to improve confidence in targeting erosion rehabilitation. However, our approach to consistently apply 2–3 year DoDs to contrasting gully morphologies enabled capture of more intense geomorphic processes acting over shorter timeframes and provided valuable and timely information on (i) contrasting erosional mechanisms and erosion rates between variable gully morphologies, and (ii) rehabilitation efforts undertaken. In this paper, we take the opportunity to concisely address all the concerns raised by Daley et al. (2023a).

Published
2024
Full Text
View/download PDF

20. Ectopically expressed rhodopsin is not sensitive to X-rays

Author

Kelli Cannon, Aundrea Bartley, Lynn Dobrunz, and Mark Bolding

Subjects
Rhodopsin, X-rays, X-genetics, Optogenetics, Noninvasive neuromodulation, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Neurophysiology and neuropsychology, QP351-495
Abstract

Abstract Visual perception of X-radiation is a well-documented, but poorly understood phenomenon. Scotopic rod cells and rhodopsin have been implicated in visual responses to X-rays, however, some evidence suggests that X-rays excite the retina via a different mechanism than visible light. While rhodopsin’s role in X-ray perception is unclear, the possibility that it could function as an X-ray receptor has led to speculation that it could act as a transgenically expressed X-ray receptor. If so, it could be used to transduce transcranial X-ray signals and control the activity of genetically targeted populations of neurons in a less invasive version of optogenetics, X-genetics. Here we investigate whether human rhodopsin (hRho) is capable of transducing X-ray signals when expressed outside of the retinal environment. We use a live-cell cAMP GloSensor luminescence assay to measure cAMP decreases in hRho-expressing HEK293 cells in response to visible light and X-ray stimulation. We show that cAMP GloSensor luminescence decreases are not observed in hRho-expressing HEK293 cells in response to X-ray stimulation, despite the presence of robust responses to visible light. Additionally, irradiation had no significant effect on cAMP GloSensor responses to subsequent visible light stimulation. These results suggest that ectopically expressed rhodopsin does not function as an X-ray receptor and is not capable of transducing transcranial X-ray signals into neural activity for X-ray mediated, genetically targeted neuromodulation.

Published
2024
Full Text
View/download PDF

21. Embedding Wellbeing in Career Development Practice: Trialling a New Structure for Guidance Conversations in Scotland and Wales

Author

Christian Percy, Erin Bartley, Liane Hambly, Deirdre Hughes, and Nikki Lawrence

Abstract

Research has established powerful relationships between career guidance, work, and wellbeing. However, some practitioners have only low or moderate confidence in using guidance to support wellbeing. Catalysed by COVID-19, this practitioner-researcher collaboration explored the question: how can we embed wellbeing more explicitly into guidance practice? Concerns and potential solutions were examined with 36 career development practitioners, service managers, and researchers from Canada, England, Scotland, and Wales. This article presents the results of a subsequent pilot in Scotland and Wales to test the resulting initial guidance interview framework. Quantitative evaluations, supported by four case examples, show customer wellbeing progress during initial guidance interviews and gains in practitioner confidence following training.

Published
2024
Full Text
View/download PDF

23. Management Processes

Author

Hirsch, Dennis, Bartley, Timothy, Chandrasekaran, Aravind, Norris, Davon, Parthasarathy, Srinivasan, Turner, Piers Norris, Hirsch, Dennis, Bartley, Timothy, Chandrasekaran, Aravind, Norris, Davon, Parthasarathy, Srinivasan, and Turner, Piers Norris

Published
2024
Full Text
View/download PDF

24. Introduction

Author

Hirsch, Dennis, Bartley, Timothy, Chandrasekaran, Aravind, Norris, Davon, Parthasarathy, Srinivasan, Turner, Piers Norris, Hirsch, Dennis, Bartley, Timothy, Chandrasekaran, Aravind, Norris, Davon, Parthasarathy, Srinivasan, and Turner, Piers Norris

Published
2024
Full Text
View/download PDF

25. Studying Data Ethics Management: Research Methodology

Author

Hirsch, Dennis, Bartley, Timothy, Chandrasekaran, Aravind, Norris, Davon, Parthasarathy, Srinivasan, Turner, Piers Norris, Hirsch, Dennis, Bartley, Timothy, Chandrasekaran, Aravind, Norris, Davon, Parthasarathy, Srinivasan, and Turner, Piers Norris

Published
2024
Full Text
View/download PDF

26. Technical Solutions

Author

Hirsch, Dennis, Bartley, Timothy, Chandrasekaran, Aravind, Norris, Davon, Parthasarathy, Srinivasan, Turner, Piers Norris, Hirsch, Dennis, Bartley, Timothy, Chandrasekaran, Aravind, Norris, Davon, Parthasarathy, Srinivasan, and Turner, Piers Norris

Published
2024
Full Text
View/download PDF

27. Management Structures and Functions

Author

Hirsch, Dennis, Bartley, Timothy, Chandrasekaran, Aravind, Norris, Davon, Parthasarathy, Srinivasan, Turner, Piers Norris, Hirsch, Dennis, Bartley, Timothy, Chandrasekaran, Aravind, Norris, Davon, Parthasarathy, Srinivasan, and Turner, Piers Norris

Published
2024
Full Text
View/download PDF

29. Motivations—Why Do Companies Pursue Data Ethics?

Author

Hirsch, Dennis, Bartley, Timothy, Chandrasekaran, Aravind, Norris, Davon, Parthasarathy, Srinivasan, Turner, Piers Norris, Hirsch, Dennis, Bartley, Timothy, Chandrasekaran, Aravind, Norris, Davon, Parthasarathy, Srinivasan, and Turner, Piers Norris

Published
2024
Full Text
View/download PDF

30. Drawing Substantive Lines

Author

Hirsch, Dennis, Bartley, Timothy, Chandrasekaran, Aravind, Norris, Davon, Parthasarathy, Srinivasan, Turner, Piers Norris, Hirsch, Dennis, Bartley, Timothy, Chandrasekaran, Aravind, Norris, Davon, Parthasarathy, Srinivasan, and Turner, Piers Norris

Published
2024
Full Text
View/download PDF

31. What is Business Data Ethics Management?

Author

Hirsch, Dennis, Bartley, Timothy, Chandrasekaran, Aravind, Norris, Davon, Parthasarathy, Srinivasan, Turner, Piers Norris, Hirsch, Dennis, Bartley, Timothy, Chandrasekaran, Aravind, Norris, Davon, Parthasarathy, Srinivasan, and Turner, Piers Norris

Published
2024
Full Text
View/download PDF

32. Data Analytics for the Social Good

Author

Hirsch, Dennis, Bartley, Timothy, Chandrasekaran, Aravind, Norris, Davon, Parthasarathy, Srinivasan, Turner, Piers Norris, Hirsch, Dennis, Bartley, Timothy, Chandrasekaran, Aravind, Norris, Davon, Parthasarathy, Srinivasan, and Turner, Piers Norris

Published
2024
Full Text
View/download PDF

35. Enhancing monolignol ferulate conjugate levels in poplar lignin via OsFMT1

Author

Faride Unda, Lisanne de Vries, Steven D. Karlen, Jordan Rainbow, Chengcheng Zhang, Laura E. Bartley, Hoon Kim, John Ralph, and Shawn D. Mansfield

Subjects
Lignification, Phenylpropanoid biosynthetic pathway, Feruloyl-CoA monolignol transferase, Biomass, UV–Vis spectroscopy, Cell wall characterization, Biotechnology, TP248.13-248.65, Fuel, TP315-360
Abstract

Abstract Background The phenolic polymer lignin is one of the primary chemical constituents of the plant secondary cell wall. Due to the inherent plasticity of lignin biosynthesis, several phenolic monomers have been shown to be incorporated into the polymer, as long as the monomer can undergo radicalization so it can participate in coupling reactions. In this study, we significantly enhance the level of incorporation of monolignol ferulate conjugates into the lignin polymer to improve the digestibility of lignocellulosic biomass. Results Overexpression of a rice Feruloyl-CoA Monolignol Transferase (FMT), OsFMT1, in hybrid poplar (Populus alba x grandidentata) produced transgenic trees clearly displaying increased cell wall-bound ester-linked ferulate, p-hydroxybenzoate, and p-coumarate, all of which are in the lignin cell wall fraction, as shown by NMR and DFRC. We also demonstrate the use of a novel UV–Vis spectroscopic technique to rapidly screen plants for the presence of both ferulate and p-hydroxybenzoate esters. Lastly we show, via saccharification assays, that the OsFMT1 transgenic p oplars have significantly improved processing efficiency compared to wild-type and Angelica sinensis-FMT-expressing poplars. Conclusions The findings demonstrate that OsFMT1 has a broad substrate specificity and a higher catalytic efficiency compared to the previously published FMT from Angelica sinensis (AsFMT). Importantly, enhanced wood processability makes OsFMT1 a promising gene to optimize the composition of lignocellulosic biomass.

Published
2024
Full Text
View/download PDF

37. Conclusion

Author

Hirsch, Dennis, Bartley, Timothy, Chandrasekaran, Aravind, Norris, Davon, Parthasarathy, Srinivasan, Turner, Piers Norris, Hirsch, Dennis, Bartley, Timothy, Chandrasekaran, Aravind, Norris, Davon, Parthasarathy, Srinivasan, and Turner, Piers Norris

Published
2024
Full Text
View/download PDF

38. Optimizing Voltage for Effective X-ray Computed Tomography Scan: A Study on Varied Soil Bulk Densities and Container Sizes

Author

Jagdeep Singh, Andrii Shmatok, Alvaro Sanz-Saez, Steve Brown, Jenny Koebernick, Barton C. Prorok, and Paul C. Bartley III

Subjects
bulk density, crop roots, inverse prediction, logistic model, penetration plateau, Plant culture, SB1-1110
Abstract

Numerous studies have highlighted the role of X-ray computed tomography (X-ray CT) in understanding root architecture. Nevertheless, setting definitive scanning parameters for diverse soils in varied container sizes remains challenging. This study investigates the influence of X-ray CT system voltage on the penetration capability in diverse soils and container sizes, focusing on two key parameters: (1) gray values, which indicate X-ray attenuation and contribute to image contrast, and (2) signal-to-noise ratio, a measure of image clarity. Five soil samples were collected from various depths within a soil profile to encompass bulk density values ranging from 1.34 to 1.84 g·cm−3 to conduct the experiment. Containers with dimensions of 6 × 6 × 6 cm³, 8 × 8 × 6 cm³, 10 × 10 × 6 cm³, 12 × 12 × 6 cm³, 14 × 14 × 6 cm³, and 16 × 16 × 6 cm³ were used. Voltage levels spanning 75 to 225 kV, in 25-kV increments, were applied to each sample. The observed gray values of the X-ray images were fitted using a logistic model of three parameters. Results showed that increasing voltage leads to enhanced penetration up to a plateau point, irrespective of soil density or container size. This plateau could potentially yield higher quality scans, given that lower voltages result in subdued gray values and reduced image contrast. Notably, it was observed that soil properties, including mineral composition, directly affect image gray values. This study established optimal voltage settings for specific soil types at fixed densities, offering valuable insights for researchers investigating soil–root interactions. Although the current findings are based on five soils, a more extensive sampling encompassing diverse soil textures and densities is necessary for a comprehensive understanding of X-ray penetration behavior across various soil types.

Published
2024
Full Text
View/download PDF

39. Examining the value of mental health awareness training for soccer coaching license candidates

Author

Laura McLane, José M. Oliva-Lozano, Michele Kerulis, Rick Cost, Jessica Bartley, and George Chiampas

Subjects
Mental health, Soccer, Coaching education, Coaches, Elite athlete, Player, Sports medicine, RC1200-1245
Abstract

Many coaches encounter athletes and/or staff members with mental health concerns. Recognizing and referring individuals to support resources is vital for providing necessary assistance. Awareness and recognition of mental health issues enable coaches to create an inclusive and supportive environment where everyone can perform their best. This article examines the experiences of participants in U.S. Soccer's Coaching License Courses to understand the frequency they have experienced supporting athletes or staff with mental health challenges and their exposure, interest, perceived value to training in mental health awareness. This observational, cross-sectional study involved a survey following a free mental health awareness presentation. The results of this study showed: (a) a high prevalence of participants have supported athletes or staff in their environment with challenges related to their mental health (82.19 %); (b) a majority of participants had no previous training in recognition or management of mental health related issues (56.65 %); (c) a majority of participants worked with youth athletes (60.16 %); and (d) nearly all participants felt that there was value in having training in mental health for their role as a coach or administrator (98.71 %). In conclusion, coaches and administrators in soccer desire more mental health awareness training. The prevalence to which they have supported individuals with mental health challenges emphasizes the continued need for training and access to mental health resources. Additionally, incorporating training and awareness into all coaching license levels should be prioritized, making it a requirement to comprehensively support athletes and staff both on and off the field.

Published
2024
Full Text
View/download PDF

40. Stratified analyses refine association between TLR7 rare variants and severe COVID-19

Author

Jannik Boos, Caspar I. van der Made, Gayatri Ramakrishnan, Eamon Coughlan, Rosanna Asselta, Britt-Sabina Löscher, Luca V.C. Valenti, Rafael de Cid, Luis Bujanda, Antonio Julià, Erola Pairo-Castineira, J. Kenneth Baillie, Sandra May, Berina Zametica, Julia Heggemann, Agustín Albillos, Jesus M. Banales, Jordi Barretina, Natalia Blay, Paolo Bonfanti, Maria Buti, Javier Fernandez, Sara Marsal, Daniele Prati, Luisa Ronzoni, Nicoletta Sacchi, Joachim L. Schultze, Olaf Riess, Andre Franke, Konrad Rawlik, David Ellinghaus, Alexander Hoischen, Axel Schmidt, Kerstin U. Ludwig, Valeria Rimoldi, Elvezia M. Paraboschi, Alessandra Bandera, Flora Peyvandi, Giacomo Grasselli, Francesco Blasi, Francesco Malvestiti, Serena Pelusi, Cristiana Bianco, Lorenzo Miano, Angela Lombardi, Pietro Invernizzi, Alessio Gerussi, Giuseppe Citerio, Andrea Biondi, Maria Grazia Valsecchi, Marina Elena Cazzaniga, Giuseppe Foti, Ilaria Beretta, Mariella D'Angiò, Laura Rachele Bettini, Xavier Farré, Susana Iraola-Guzmán, Manolis Kogevinas, Gemma Castaño-Vinyals, Koldo Garcia-Etxebarria, Beatriz Nafria, Mauro D'Amato, Adriana Palom, Colin Begg, Sara Clohisey, Charles Hinds, Peter Horby, Julian Knight, Lowell Ling, David Maslove, Danny McAuley, Johnny Millar, Hugh Montgomery, Alistair Nichol, Peter J.M. Openshaw, Alexandre C. Pereira, Chris P. Ponting, Kathy Rowan, Malcolm G. Semple, Manu Shankar-Hari, Charlotte Summers, Timothy Walsh, Latha Aravindan, Ruth Armstrong, Heather Biggs, Ceilia Boz, Adam Brown, Richard Clark, Audrey Coutts, Judy Coyle, Louise Cullum, Sukamal Das, Nicky Day, Lorna Donnelly, Esther Duncan, Angie Fawkes, Paul Fineran, Max Head Fourman, Anita Furlong, James Furniss, Bernadette Gallagher, Tammy Gilchrist, Ailsa Golightly, Fiona Griffiths, Katarzyna Hafezi, Debbie Hamilton, Ross Hendry, Andy Law, Dawn Law, Rachel Law, Sarah Law, Rebecca Lidstone-Scott, Louise Macgillivray, Alan Maclean, Hanning Mal, Sarah McCafferty, Ellie Mcmaster, Jen Meikle, Shona C. Moore, Kirstie Morrice, Lee Murphy, Sheena Murphy, Mybaya Hellen, Wilna Oosthuyzen, Chenqing Zheng, Jiantao Chen, Nick Parkinson, Trevor Paterson, Katherine Schon, Andrew Stenhouse, Mihaela Das, Maaike Swets, Helen Szoor-McElhinney, Filip Taneski, Lance Turtle, Tony Wackett, Mairi Ward, Jane Weaver, Nicola Wrobel, Marie Zechner, Gill Arbane, Aneta Bociek, Sara Campos, Neus Grau, Tim Owen Jones, Rosario Lim, Martina Marotti, Marlies Ostermann, Christopher Whitton, Zoe Alldis, Raine Astin-Chamberlain, Fatima Bibi, Jack Biddle, Sarah Blow, Matthew Bolton, Catherine Borra, Ruth Bowles, Maudrian Burton, Yasmin Choudhury, David Collier, Amber Cox, Amy Easthope, Patrizia Ebano, Stavros Fotiadis, Jana Gurasashvili, Rosslyn Halls, Pippa Hartridge, Delordson Kallon, Jamila Kassam, Ivone Lancoma-Malcolm, Maninderpal Matharu, Peter May, Oliver Mitchelmore, Tabitha Newman, Mital Patel, Jane Pheby, Irene Pinzuti, Zoe Prime, Oleksandra Prysyazhna, Julian Shiel, Melanie Taylor, Carey Tierney, Suzanne Wood, Anne Zak, Olivier Zongo, Stephen Bonner, Keith Hugill, Jessica Jones, Steven Liggett, Evie Headlam, Nageswar Bandla, Minnie Gellamucho, Michelle Davies, Christopher Thompson, Marwa Abdelrazik, Dhanalakshmi Bakthavatsalam, Munzir Elhassan, Arunkumar Ganesan, Anne Haldeos, Jeronimo Moreno-Cuesta, Dharam Purohit, Rachel Vincent, Kugan Xavier, Kumar Rohit, Frater Alasdair, Malik Saleem, Carter David, Jenkins Samuel, Zoe Lamond, Wall Alanna, Jaime Fernandez-Roman, David O. Hamilton, Emily Johnson, Brian Johnston, Maria Lopez Martinez, Suleman Mulla, David Shaw, Alicia A.C. Waite, Victoria Waugh, Ingeborg D. Welters, Karen Williams, Anna Cavazza, Maeve Cockrell, Eleanor Corcoran, Maria Depante, Clare Finney, Ellen Jerome, Mark McPhail, Monalisa Nayak, Harriet Noble, Kevin O'Reilly, Evita Pappa, Rohit Saha, Sian Saha, John Smith, Abigail Knighton, David Antcliffe, Dorota Banach, Stephen Brett, Phoebe Coghlan, Ziortza Fernandez, Anthony Gordon, Roceld Rojo, Sonia Sousa Arias, Maie Templeton, Megan Meredith, Lucy Morris, Lucy Ryan, Amy Clark, Julia Sampson, Cecilia Peters, Martin Dent, Margaret Langley, Saima Ashraf, Shuying Wei, Angela Andrew, Archana Bashyal, Neil Davidson, Paula Hutton, Stuart McKechnie, Jean Wilson, David Baptista, Rebecca Crowe, Rita Fernandes, Rosaleen Herdman-Grant, Anna Joseph, Denise O'Connor, Meryem Allen, Adam Loveridge, India McKenley, Eriko Morino, Andres Naranjo, Richard Simms, Kathryn Sollesta, Andrew Swain, Harish Venkatesh, Jacyntha Khera, Jonathan Fox, Gillian Andrew, Lucy Barclay, Marie Callaghan, Rachael Campbell, Sarah Clark, Dave Hope, Lucy Marshall, Corrienne McCulloch, Kate Briton, Jo Singleton, Sohphie Birch, Lutece Brimfield, Zoe Daly, David Pogson, Steve Rose, Ceri Battle, Elaine Brinkworth, Rachel Harford, Carl Murphy, Luke Newey, Tabitha Rees, Marie Williams, Sophie Arnold, Petra Polgarova, Katerina Stroud, Eoghan Meaney, Megan Jones, Anthony Ng, Shruti Agrawal, Nazima Pathan, Deborah White, Esther Daubney, Kay Elston, Lina Grauslyte, Musarat Hussain, Mandeep Phull, Tatiana Pogreban, Lace Rosaroso, Erika Salciute, George Franke, Joanna Wong, Aparna George, Laura Ortiz-Ruiz de Gordoa, Emily Peasgood, Claire Phillips, Michelle Bates, Jo Dasgin, Jaspret Gill, Annette Nilsson, James Scriven, Carlos Castro Delgado, Deborah Dawson, Lijun Ding, Georgia Durrant, Obiageri Ezeobu, Sarah Farnell-Ward, Abiola Harrison, Rebecca Kanu, Susannah Leaver, Elena Maccacari, Soumendu Manna, Romina Pepermans Saluzzio, Joana Queiroz, Tinashe Samakomva, Christine Sicat, Joana Texeira, Edna Fernandes Da Gloria, Ana Lisboa, John Rawlins, Jisha Mathew, Ashley Kinch, William James Hurt, Nirav Shah, Victoria Clark, Maria Thanasi, Nikki Yun, Kamal Patel, Sara Bennett, Emma Goodwin, Matthew Jackson, Alissa Kent, Clare Tibke, Wiesia Woodyatt, Ahmed Zaki, Azmerelda Abraheem, Peter Bamford, Kathryn Cawley, Charlie Dunmore, Maria Faulkner, Rumanah Girach, Helen Jeffrey, Rhianna Jones, Emily London, Imrun Nagra, Farah Nasir, Hannah Sainsbury, Clare Smedley, Tahera Patel, Matthew Smith, Srikanth Chukkambotla, Aayesha Kazi, Janice Hartley, Joseph Dykes, Muhammad Hijazi, Sarah Keith, Meherunnisa Khan, Janet Ryan-Smith, Philippa Springle, Jacqueline Thomas, Nick Truman, Samuel Saad, Dabheoc Coleman, Christopher Fine, Roseanna Matt, Bethan Gay, Jack Dalziel, Syamlan Ali, Drew Goodchild, Rhiannan Harling, Ravi Bhatterjee, Wendy Goddard, Chloe Davison, Stephen Duberly, Jeanette Hargreaves, Rachel Bolton, Miriam Davey, David Golden, Rebecca Seaman, Shiney Cherian, Sean Cutler, Anne Emma Heron, Anna Roynon-Reed, Tamas Szakmany, Gemma Williams, Owen Richards, Yusuf Cheema, Hollie Brooke, Sarah Buckley, Jose Cebrian Suarez, Ruth Charlesworth, Karen Hansson, John Norris, Alice Poole, Alastair Rose, Rajdeep Sandhu, Brendan Sloan, Elizabeth Smithson, Muthu Thirumaran, Veronica Wagstaff, Alexandra Metcalfe, Mark Brunton, Jess Caterson, Holly Coles, Matthew Frise, Sabi Gurung Rai, Nicola Jacques, Liza Keating, Emma Tilney, Shauna Bartley, Parminder Bhuie, Sian Gibson, Amanda Lyle, Fiona McNeela, Jayachandran Radhakrishnan, Alistair Hughes, Bryan Yates, Jessica Reynolds, Helen Campbell, Maria Thompsom, Steve Dodds, Stacey Duffy, Sandra Greer, Karen Shuker, Ascanio Tridente, Reena Khade, Ashok Sundar, George Tsinaslanidis, Isobel Birkinshaw, Joseph Carter, Kate Howard, Joanne Ingham, Rosie Joy, Harriet Pearson, Samantha Roche, Zoe Scott, Hollie Bancroft, Mary Bellamy, Margaret Carmody, Jacqueline Daglish, Faye Moore, Joanne Rhodes, Mirriam Sangombe, Salma Kadiri, Maria Croft, Ian White, Victoria Frost, Maia Aquino, Rajeev Jha, Vinodh Krishnamurthy, Lai Lim, Li Lim, Edward Combes, Teishel Joefield, Sonja Monnery, Valerie Beech, Sallyanne Trotman, Christine Almaden-Boyle, Pauline Austin, Louise Cabrelli, Stephen Cole, Matt Casey, Susan Chapman, Clare Whyte, Yolanda Baird, Aaron Butler, Indra Chadbourn, Linda Folkes, Heather Fox, Amy Gardner, Raquel Gomez, Gillian Hobden, Luke Hodgson, Kirsten King, Michael Margarson, Tim Martindale, Emma Meadows, Dana Raynard, Yvette Thirlwall, David Helm, Jordi Margalef, Kristine Criste, Rebecca Cusack, Kim Golder, Hannah Golding, Oliver Jones, Samantha Leggett, Michelle Male, Martyna Marani, Kirsty Prager, Toran Williams, Belinda Roberts, Karen Salmon, Peter Anderson, Katie Archer, Karen Austin, Caroline Davis, Alison Durie, Olivia Kelsall, Jessica Thrush, Charlie Vigurs, Laura Wild, Hannah-Louise Wood, Helen Tranter, Alison Harrison, Nicholas Cowley, Michael McAlindon, Andrew Burtenshaw, Stephen Digby, Emma Low, Aled Morgan, Naiara Cother, Tobias Rankin, Sarah Clayton, Alex McCurdy, Cecilia Ahmed, Balvinder Baines, Sarah Clamp, Julie Colley, Risna Haq, Anne Hayes, Jonathan Hulme, Samia Hussain, Sibet Joseph, Rita Kumar, Zahira Maqsood, Manjit Purewal, Leonie Benham, Zena Bradshaw, Joanna Brown, Melanie Caswell, Jason Cupitt, Sarah Melling, Stephen Preston, Nicola Slawson, Emma Stoddard, Scott Warden, Bethan Deacon, Ceri Lynch, Carla Pothecary, Lisa Roche, Gwenllian Sera Howe, Jayaprakash Singh, Keri Turner, Hannah Ellis, Natalie Stroud, Jodie Hunt, Joy Dearden, Emma Dobson, Andy Drummond, Michelle Mulcahy, Sheila Munt, Grainne O'Connor, Jennifer Philbin, Chloe Rishton, Redmond Tully, Sarah Winnard, Susanne Cathcart, Katharine Duffy, Alex Puxty, Kathryn Puxty, Lynne Turner, Jane Ireland, Gary Semple, Kate Long, Simon Whiteley, Elizabeth Wilby, Bethan Ogg, Amanda Cowton, Andrea Kay, Melanie Kent, Kathryn Potts, Ami Wilkinson, Suzanne Campbell, Ellen Brown, Julie Melville, Jay Naisbitt, Rosane Joseph, Maria Lazo, Olivia Walton, Alan Neal, Peter Alexander, Schvearn Allen, Joanne Bradley-Potts, Craig Brantwood, Jasmine Egan, Timothy Felton, Grace Padden, Luke Ward, Stuart Moss, Susannah Glasgow, Lynn Abel, Michael Brett, Brian Digby, Lisa Gemmell, James Hornsby, Patrick MacGoey, Pauline O'Neil, Richard Price, Natalie Rodden, Kevin Rooney, Radha Sundaram, Nicola Thomson, Bridget Hopkins, Laura Thrasyvoulou, Heather Willis, Martyn Clark, Martina Coulding, Edward Jude, Jacqueline McCormick, Oliver Mercer, Darsh Potla, Hafiz Rehman, Heather Savill, Victoria Turner, Charlotte Downes, Kathleen Holding, Katie Riches, Mary Hilton, Mel Hayman, Deepak Subramanian, Priya Daniel, Oluronke Adanini, Nikhil Bhatia, Maines Msiska, Rebecca Collins, Ian Clement, Bijal Patel, A. Gulati, Carole Hays, K. Webster, Anne Hudson, Andrea Webster, Elaine Stephenson, Louise McCormack, Victoria Slater, Rachel Nixon, Helen Hanson, Maggie Fearby, Sinead Kelly, Victoria Bridgett, Philip Robinson, Julie Camsooksai, Charlotte Humphrey, Sarah Jenkins, Henrik Reschreiter, Beverley Wadams, Yasmin Death, Victoria Bastion, Daphene Clarke, Beena David, Harriet Kent, Rachel Lorusso, Gamu Lubimbi, Sophie Murdoch, Melchizedek Penacerrada, Alastair Thomas, Jennifer Valentine, Ana Vochin, Retno Wulandari, Brice Djeugam, Gillian Bell, Katy English, Amro Katary, Louise Wilcox, Michelle Bruce, Karen Connolly, Tracy Duncan, Helen T-Michael, Gabriella Lindergard, Samuel Hey, Claire Fox, Jordan Alfonso, Laura Jayne Durrans, Jacinta Guerin, Bethan Blackledge, Jade Harris, Martin Hruska, Ayaa Eltayeb, Thomas Lamb, Tracey Hodgkiss, Lisa Cooper, Joanne Rothwell, Angela Allan, Felicity Anderson, Callum Kaye, Jade Liew, Jasmine Medhora, Teresa Scott, Erin Trumper, Adriana Botello, Liana Lankester, Nikitas Nikitas, Colin Wells, Bethan Stowe, Kayleigh Spencer, Craig Brandwood, Lara Smith, Katie Birchall, Laurel Kolakaluri, Deborah Baines, Anila Sukumaran, Elena Apetri, Cathrine Basikolo, Laura Catlow, Bethan Charles, Paul Dark, Reece Doonan, Alice Harvey, Daniel Horner, Karen Knowles, Stephanie Lee, Diane Lomas, Chloe Lyons, Tracy Marsden, Danielle McLaughlan, Liam McMorrow, Jessica Pendlebury, Jane Perez, Maria Poulaka, Nicola Proudfoot, Melanie Slaughter, Kathryn Slevin, Vicky Thomas, Danielle Walker, Angiy Michael, Matthew Collis, Tracey Cosier, Gemma Millen, Neil Richardson, Natasha Schumacher, Heather Weston, James Rand, Nicola Baxter, Steven Henderson, Sophie Kennedy-Hay, Christopher McParland, Laura Rooney, Malcolm Sim, Gordan McCreath, Louise Akeroyd, Shereen Bano, Matt Bromley, Lucy Gurr, Tom Lawton, James Morgan, Kirsten Sellick, Deborah Warren, Brian Wilkinson, Janet McGowan, Camilla Ledgard, Amelia Stacey, Kate Pye, Ruth Bellwood, Michael Bentley, Jeremy Bewley, Zoe Garland, Lisa Grimmer, Bethany Gumbrill, Rebekah Johnson, Katie Sweet, Denise Webster, Georgia Efford, Karen Convery, Deirdre Fottrell-Gould, Lisa Hudig, Jocelyn Keshet-Price, Georgina Randell, Katie Stammers, Maria Bokhari, Vanessa Linnett, Rachael Lucas, Wendy McCormick, Jenny Ritzema, Amanda Sanderson, Helen Wild, Anthony Rostron, Alistair Roy, Lindsey Woods, Sarah Cornell, Fiona Wakinshaw, Kimberley Rogerson, Jordan Jarmain, Robert Parker, Amie Reddy, Ian Turner-Bone, Laura Wilding, Peter Harding, Caroline Abernathy, Louise Foster, Andrew Gratrix, Vicky Martinson, Priyai Parkinson, Elizabeth Stones, Llucia Carbral-Ortega, Georgia Bercades, David Brealey, Ingrid Hass, Niall MacCallum, Gladys Martir, Eamon Raith, Anna Reyes, Deborah Smyth, Letizia Zitter, Sarah Benyon, Suzie Marriott, Linda Park, Samantha Keenan, Elizabeth Gordon, Helen Quinn, Kizzy Baines, Lenka Cagova, Adama Fofano, Lucie Garner, Helen Holcombe, Sue Mepham, Alice Michael Mitchell, Lucy Mwaura, Krithivasan Praman, Alain Vuylsteke, Julie Zamikula, Bally Purewal, Vanessa Rivers, Stephanie Bell, Hayley Blakemore, Borislava Borislavova, Beverley Faulkner, Emma Gendall, Elizabeth Goff, Kati Hayes, Matt Thomas, Ruth Worner, Kerry Smith, Deanna Stephens, Louise Mew, Esther Mwaura, Richard Stewart, Felicity Williams, Lynn Wren, Sara-Beth Sutherland, Emily Bevan, Jane Martin, Dawn Trodd, Geoff Watson, Caroline Wrey Brown, Amy Collins, Waqas Khaliq, Estefania Treus Gude, Olugbenga Akinkugbe, Alasdair Bamford, Emily Beech, Holly Belfield, Michael Bell, Charlene Davies, Gareth A.L. Jones, Tara McHugh, Hamza Meghari, Lauran O'Neill, Mark J. Peters, Samiran Ray, Ana Luisa Tomas, Iona Burn, Geraldine Hambrook, Katarina Manso, Ruth Penn, Pradeep Shanmugasundaram, Julie Tebbutt, Danielle Thornton, Jade Cole, Rhys Davies, Donna Duffin, Helen Hill, Ben Player, Emma Thomas, Angharad Williams, Denise Griffin, Nycola Muchenje, Mcdonald Mupudzi, Richard Partridge, Jo-Anna Conyngham, Rachel Thomas, Mary Wright, Maria Alvarez Corral, Reni Jacob, Cathy Jones, Craig Denmade, Sarah Beavis, Katie Dale, Rachel Gascoyne, Joanne Hawes, Kelly Pritchard, Lesley Stevenson, Amanda Whileman, Patricia Doble, Joanne Hutter, Corinne Pawley, Charmaine Shovelton, Marius Vaida, Deborah Butcher, Susie O'Sullivan, Nicola Butterworth-Cowin, Norfaizan Ahmad, Joann Barker, Kris Bauchmuller, Sarah Bird, Kay Cawthron, Kate Harrington, Yvonne Jackson, Faith Kibutu, Becky Lenagh, Shamiso Masuko, Gary H. Mills, Ajay Raithatha, Matthew Wiles, Jayne Willson, Helen Newell, Alison Lye, Lorenza Nwafor, Claire Jarman, Sarah Rowland-Jones, David Foote, Joby Cole, Roger Thompson, James Watson, Lisa Hesseldon, Irene Macharia, Luke Chetam, Jacqui Smith, Amber Ford, Samantha Anderson, Kathryn Birchall, Kay Housley, Sara Walker, Leanne Milner, Helena Hanratty, Helen Trower, Patrick Phillips, Simon Oxspring, Ben Donne, Catherine Jardine, Dewi Williams, Alasdair Hay, Rebecca Flanagan, Gareth Hughes, Scott Latham, Emma McKenna, Jennifer Anderson, Robert Hull, Kat Rhead, Carina Cruz, Natalie Pattison, Rob Charnock, Denise McFarland, Denise Cosgrove, Ashar Ahmed, Anna Morris, Srinivas Jakkula, Asifa Ali, Megan Brady, Sam Dale, Annalisa Dance, Lisa Gledhill, Jill Greig, Kathryn Hanson, Kelly Holdroyd, Marie Home, Diane Kelly, Ross Kitson, Lear Matapure, Deborah Melia, Samantha Mellor, Tonicha Nortcliffe, Jez Pinnell, Matthew Robinson, Lisa Shaw, Ryan Shaw, Lesley Thomis, Alison Wilson, Tracy Wood, Lee-Ann Bayo, Ekta Merwaha, Tahira Ishaq, Sarah Hanley, Meg Hibbert, Dariusz Tetla, Chrsitopher Woodford, Latha Durga, Gareth Kennard-Holden, Debbie Branney, Jordan Frankham, Sally Pitts, Nigel White, Shondipon Laha, Mark Verlander, Alexandra Williams, Abdelhakim Altabaibeh, Ana Alvaro, Kayleigh Gilbert, Louise Ma, Loreta Mostoles, Chetan Parmar, Kathryn Simpson, Champa Jetha, Lauren Booker, Anezka Pratley, Colene Adams, Anita Agasou, Tracie Arden, Amy Bowes, Pauline Boyle, Mandy Beekes, Heather Button, Nigel Capps, Mandy Carnahan, Anne Carter, Danielle Childs, Denise Donaldson, Kelly Hard, Fran Hurford, Yasmin Hussain, Ayesha Javaid, James Jones, Sanal Jose, Michael Leigh, Terry Martin, Helen Millward, Nichola Motherwell, Rachel Rikunenko, Jo Stickley, Julie Summers, Louise Ting, Helen Tivenan, Louise Tonks, Rebecca Wilcox, Maureen Holland, Natalie Keenan, Marc Lyons, Helen Wassall, Chris Marsh, Mervin Mahenthran, Emma Carter, Thomas Kong, Helen Blackman, Ben Creagh-Brown, Sinead Donlon, Natalia Michalak-Glinska, Sheila Mtuwa, Veronika Pristopan, Armorel Salberg, Eleanor Smith, Sarah Stone, Charles Piercy, Jerik Verula, Dorota Burda, Rugia Montaser, Lesley Harden, Irving Mayangao, Cheryl Marriott, Paul Bradley, Celia Harris, Susan Anderson, Eleanor Andrews, Janine Birch, Emma Collins, Kate Hammerton, Ryan O'Leary, Michele Clark, Sarah Purvis, Russell Barber, Claire Hewitt, Annette Hilldrith, Karen Jackson-Lawrence, Sarah Shepardson, Maryanne Wills, Susan Butler, Silvia Tavares, Amy Cunningham, Julia Hindale, Sarwat Arif, Sarah Bean, Karen Burt, Michael Spivey, Carrie Demetriou, Charlotte Eckbad, Sarah Hierons, Lucy Howie, Sarah Mitchard, Lidia Ramos, Alfredo Serrano-Ruiz, Katie White, Fiona Kelly, Daniele Cristiano, Natalie Dormand, Zohreh Farzad, Mahitha Gummadi, Kamal Liyanage, Brijesh Patel, Sara Salmi, Geraldine Sloane, Vicky Thwaites, Mathew Varghese, Anelise C. Zborowski, John Allan, Tim Geary, Gordon Houston, Alistair Meikle, Peter O'Brien, Miranda Forsey, Agilan Kaliappan, Anne Nicholson, Joanne Riches, Mark Vertue, Elizabeth Allan, Kate Darlington, Ffyon Davies, Jack Easton, Sumit Kumar, Richard Lean, Daniel Menzies, Richard Pugh, Xinyi Qiu, Llinos Davies, Hannah Williams, Jeremy Scanlon, Gwyneth Davies, Callum Mackay, Joannne Lewis, Stephanie Rees, Metod Oblak, Monica Popescu, Mini Thankachen, Andrew Higham, Kerry Simpson, Jayne Craig, Rosie Baruah, Sheila Morris, Susie Ferguson, Amy Shepherd, Luke Stephen Prockter Moore, Marcela Paola Vizcaychipi, Laura Gomes de Almeida Martins, Jaime Carungcong, Inthakab Ali Mohamed Ali, Karen Beaumont, Mark Blunt, Zoe Coton, Hollie Curgenven, Mohamed Elsaadany, Kay Fernandes, Sameena Mohamed Ally, Harini Rangarajan, Varun Sarathy, Sivarupan Selvanayagam, Dave Vedage, Matthew White, Mandy Gill, Paul Paul, Valli Ratnam, Sarah Shelton, Inez Wynter, Siobhain Carmody, Valerie Joan Page, Claire Marie Beith, Karen Black, Suzanne Clements, Alan Morrison, Dominic Strachan, Margaret Taylor, Michelle Clarkson, Stuart D'Sylva, Kathryn Norman, Fiona Auld, Joanne Donnachie, Ian Edmond, Lynn Prentice, Nikole Runciman, Dario Salutous, Lesley Symon, Anne Todd, Patricia Turner, Abigail Short, Laura Sweeney, Euan Murdoch, Dhaneesha Senaratne, Michaela Hill, Thogulava Kannan, Wild Laura, Rikki Crawley, Abigail Crew, Mishell Cunningham, Allison Daniels, Laura Harrison, Susan Hope, Ken Inweregbu, Sian Jones, Nicola Lancaster, Jamie Matthews, Alice Nicholson, Gemma Wray, Helen Langton, Rachel Prout, Malcolm Watters, Catherine Novis, Anthony Barron, Ciara Collins, Sundeep Kaul, Heather Passmore, Claire Prendergast, Anna Reed, Paula Rogers, Rajvinder Shokkar, Meriel Woodruff, Hayley Middleton, Oliver Polgar, Claire Nolan, Kanta Mahay, Dawn Collier, Anil Hormis, Victoria Maynard, Cheryl Graham, Rachel Walker, Ellen Knights, Alicia Price, Alice Thomas, Chris Thorpe, Teresa Behan, Caroline Burnett, Jonathan Hatton, Elaine Heeney, Atideb Mitra, Maria Newton, Rachel Pollard, Rachael Stead, Vishal Amin, Elena Anastasescu, Vikram Anumakonda, Komala Karthik, Rizwana Kausar, Karen Reid, Jacqueline Smith, Janet Imeson-Wood, Denise Skinner, Jane Gaylard, Dee Mullan, Julie Newman, Alison Brown, Vikki Crickmore, Gabor Debreceni, Joy Wilkins, Liz Nicol, Rosie Reece-Anthony, Mark Birt, Alison Ghosh, Emma Williams, Louise Allen, Eva Beranova, Nikki Crisp, Joanne Deery, Tracy Hazelton, Alicia Knight, Carly Price, Sorrell Tilbey, Salah Turki, Sharon Turney, Joshua Cooper, Cheryl Finch, Sarah Liderth, Alison Quinn, Natalia Waddington, Tina Coventry, Susan Fowler, Michael MacMahon, Amanda McGregor, Anne Cowley, Judith Highgate, Jane Gregory, Susan O'Connell, Tim Smith, Luigi Barberis, Shameer Gopal, Nichola Harris, Victoria Lake, Stella Metherell, Elizabeth Radford, Amelia Daniel, Joanne Finn, Rajnish Saha, Nikki White, Phil Donnison, Fiona Trim, Beena Eapen, Jenny Birch, Laura Bough, Josie Goodsell, Rebecca Tutton, Patricia Williams, Sarah Williams, Barbara Winter-Goodwin, Ailstair Nichol, Kathy Brickell, Michelle Smyth, Lorna Murphy, Samantha Coetzee, Alistair Gales, Igor Otahal, Meena Raj, Craig Sell, Paula Hilltout, Jayne Evitts, Amanda Tyler, Joanne Waldron, Kate Beesley, Sarah Board, Agnieszka Kubisz-Pudelko, Alison Lewis, Jess Perry, Lucy Pippard, Di Wood, Clare Buckley, Peter Barry, Neil Flint, Patel Rekha, Dawn Hales, Lara Bunni, Claire Jennings, Monica Latif, Rebecca Marshall, Gayathri Subramanian, Peter J. McGuigan, Christopher Wasson, Stephanie Finn, Jackie Green, Erin Collins, Bernadette King, Andy Campbell, Sara Smuts, Joseph Duffield, Oliver Smith, Lewis Mallon, Watkins Claire, Liam Botfield, Joanna Butler, Catherine Dexter, Jo Fletcher, Atul Garg, Aditya Kuravi, Poonam Ranga, Emma Virgilio, Zakaula Belagodu, Bridget Fuller, Anca Gherman, Olumide Olufuwa, Remi Paramsothy, Carmel Stuart, Naomi Oakley, Charlotte Kamundi, David Tyl, Katy Collins, Pedro Silva, June Taylor, Laura King, Charlotte Coates, Maria Crowley, Phillipa Wakefield, Jane Beadle, Laura Johnson, Janet Sargeant, Madeleine Anderson, Ailbhe Brady, Rebekah Chan, Jeff Little, Shane McIvor, Helena Prady, Helen Whittle, Bijoy Mathew, Ben Attwood, Penny Parsons, Geraldine Ward, Pamela Bremmer, West Joe, Baird Tracy, Ruddy Jim, Ellie Davies, Sonia Sathe, Catherine Dennis, Alastair McGregor, Victoria Parris, Sinduya Srikaran, Anisha Sukha, Noreen Clarke, Jonathan Whiteside, Mairi Mascarenhas, Avril Donaldson, Joanna Matheson, Fiona Barrett, Marianne O'Hara, Laura Okeefe, Clare Bradley, Christine Eastgate-Jackson, Helder Filipe, Daniel Martin, Amitaa Maharajh, Sara Mingo Garcia, Glykeria Pakou, Mark De Neef, Kathy Dent, Elizabeth Horsley, Muhmmad Nauman Akhtar, Sandra Pearson, Dorota Potoczna, Sue Spencer, Melanie Clapham, Rosemary Harper, Una Poultney, Polly Rice, Rachel Mutch, Lisa Armstrong, Hayley Bates, Emma Dooks, Fiona Farquhar, Brigid Hairsine, Chantal McParland, Sophie Packham, Rehana Bi, Barney Scholefield, Lydia Ashton, Linsha George, Sophie Twiss, David Wright, Manish Chablani, Amy Kirkby, Kimberley Netherton, Kim Davies, Linda O'Brien, Zohra Omar, Emma Perkins, Tracy Lewis, Isobel Sutherland, Karen Burns, Dr Ben Chandler, Kerry Elliott, Janine Mallinson, Alison Turnbull, Prisca Gondo, Bernard Hadebe, Abdul Kayani, Bridgett Masunda, Taya Anderson, Dan Hawcutt, Laura O'Malley, Laura Rad, Naomi Rogers, Paula Saunderson, Kathryn Sian Allison, Deborah Afolabi, Jennifer Whitbread, Dawn Jones, Rachael Dore, Matthew Halkes, Pauline Mercer, Lorraine Thornton, Joy Dawson, Sweyn Garrioch, Melanie Tolson, Jonathan Aldridge, Ritoo Kapoor, David Loader, Karen Castle, Sally Humphreys, Ruth Tampsett, Katherine Mackintosh, Amanda Ayers, Wendy Harrison, Julie North, Suzanne Allibone, Roman Genetu, Vidya Kasipandian, Amit Patel, Ainhi Mac, Anthony Murphy, Parisa Mahjoob, Roonak Nazari, Lucy Worsley, Andrew Fagan, Thomas Bemand, Ethel Black, Arnold Dela Rosa, Ryan Howle, Shaman Jhanji, Ravishankar Rao Baikady, Kate Colette Tatham, Benjamin Thomas, Dina Bell, Rosalind Boyle, Katie Douglas, Lynn Glass, Emma Lee, Liz Lennon, Austin Rattray, Abigail Taylor, Rachel Anne Hughes, Helen Thomas, Alun Rees, Michaela Duskova, Janet Phipps, Suzanne Brooks, Michelle Edwards, Sheena Quaid, Ekaterina Watson, Adam Brayne, Emma Fisher, Jane Hunt, Peter Jackson, Duncan Kaye, Nicholas Love, Juliet Parkin, Victoria Tuckey, Lynne Van Koutrik, Sasha Carter, Benedict Andrew, Louise Findlay, Katie Adams, Jen Service, Alison Williams, Claire Cheyne, Anne Saunderson, Sam Moultrie, Miranda Odam, Kathryn Hall, Isheunesu Mapfunde, Charlotte Willis, Alex Lyon, Chunda Sri-Chandana, Joslan Scherewode, Lorraine Stephenson, Sarah Marsh, John Hardy, Henry Houlden, Eleanor Moncur, Ambreen Tariq, Arianna Tucci, Maria Hobrok, Ronda Loosley, Heather McGuinness, Helen Tench, Rebecca Wolf-Roberts, Val Irvine, Benjamin Shelley, Claire Gorman, Abhinav Gupta, Elizabeth Timlick, Rebecca Brady, Barry Milligan, Arianna Bellini, Jade Bryant, Anton Mayer, Amy Pickard, Nicholas Roe, Jason Sowter, Alex Howlett, Katy Fidler, Emma Tagliavini, and Kevin Donnelly

Subjects
SARS-CoV-2, host genetics, toll-like receptor 7, targeted sequencing, rare variants, variant collapsing analysis, Genetics, QH426-470
Abstract

Summary: Despite extensive global research into genetic predisposition for severe COVID-19, knowledge on the role of rare host genetic variants and their relation to other risk factors remains limited. Here, 52 genes with prior etiological evidence were sequenced in 1,772 severe COVID-19 cases and 5,347 population-based controls from Spain/Italy. Rare deleterious TLR7 variants were present in 2.4% of young (

Published
2024
Full Text
View/download PDF

46. Assessing gully erosion and rehabilitation using multi temporal LiDAR DEMs: Case study from the Great Barrier Reef catchments, Australia

Author

Sana Khan, Rebecca Bartley, Anne Kinsey-Henderson, and Aaron Hawdon

Subjects
Digital elevation models, (dis)connectivity, Restoration, Geomorphic change detection, Geomorphic effectiveness, GIS, Engineering (General). Civil engineering (General), TA1-2040
Abstract

Millions of dollars are being spent on gully rehabilitation to help reduce excess fine sediment delivery to the Great Barrier Reef (GBR). There is an urgent need for (i) prioritisation of active gullies for rehabilitation and (ii) the development of methodologies to inform the effectiveness of remediation. In this study we analyse DEMs of Difference derived from 0.5 m resolution 2–3 year interval multi-temporal LiDAR data collected pre and post rehabilitation at three variable gully morphologies in the Burdekin catchment. Our analysis indicates that the highest annual average fine sediment erosion rates for the untreated control gullies occur at the linear gully (53.38 t ha−1 y−1) followed by linear-alluvial gully (34.24 t ha−1 y−1) and least at the alluvial gully (14.41 t ha−1 y−1). The proportional loss or export of fine sediment from the gullies in their un-treated condition ranges from ∼68 to 90% of what is eroded, and when the gullies are treated the proportion of fine sediment that is retained in the gully proportional to what is eroded increases to ∼60% at all sites. Without pre-treatment baseline erosion rates, and additional post treatment LiDAR captures, it is difficult to quantify the treatment effectiveness. Our results offer insights in the erosion mechanisms within different geomorphic gully morphologies and rehabilitation effects in these erosional landforms. This study provides crucial knowledge of gully dynamics that can be coupled with other lines of evidence for better prioritisation of rehabilitation in the GBR catchments.

Published
2024
Full Text
View/download PDF

47. Sponge-derived matter is assimilated by coral holobionts

Author

Alicia M. Reigel, Cole G. Easson, Amy Apprill, Christopher J. Freeman, Michaela M. Bartley, and Cara L. Fiore

Subjects
Biology (General), QH301-705.5
Abstract

Abstract Coral reef biodiversity is maintained by a complex network of nutrient recycling among organisms. Sponges assimilate nutrients produced by other organisms like coral and algae, releasing them as particulate and dissolved matter, but to date, only a single trophic link between sponge-derived dissolved matter and a macroalgae has been identified. We sought to determine if sponge-coral nutrient exchange is reciprocal using a stable isotope ‘pulse-chase’ experiment to trace the uptake of 13C and 15N sponge-derived matter by the coral holobiont for three coral species (Acropora cervicornis, Orbicella faveolata, and Eunicea flexuosa). Coral holobionts incorporated 2.3–26.8x more 15N than 13C from sponge-derived matter and A. cervicornis incorporated more of both C and N than the other corals. Differential isotopic incorporation among coral species aligns with their ecophysiological characteristics (e.g., morphology, Symbiodiniaceae density). Our results elucidate a recycling pathway on coral reefs that has implications for improving coral aquaculture and management approaches.

Published
2024
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results