9 results on '"Awwad, M"'
Search Results
2. The risk of preexisting donor-specific IgG antibody with a negative flow crossmatch in kidney transplantation
- Author
-
Leising, M., Vantair, N., Awwad, M., Gilbert, A., Verbesey, J., Rosen-Bronson, S., and Timofeeva, O.
- Published
- 2024
- Full Text
- View/download PDF
3. The diagnostic utility of FIB-4 as a non-invasive tool for liver fibrosis scoring among NAFLD patients: a retrospective cross-sectional study.
- Author
-
AMER, J., ALNEES, M., SALAMEH, M., DARAGHMEH, A., KABHA, A., ALHABIL, Y., DARWISH, A., NAJAJRA, D., AWWAD, M., HAMDEH, N. ABU, and ABDOH, Q.
- Abstract
OBJECTIVE: Liver biopsy is the gold standard method to evaluate patients with non-alcoholic fatty liver disease (NAFLD). However, due to its several limitations and complications, a reliable and non-invasive marker is required to assess liver fibrosis. In this study, we compared the performance of the FIB-4 index [based on age, aspartate aminotransferase (AST), and alanine aminotransferase (ALT) levels and platelets count] with the Scheuer scoring system of liver biopsies to evaluate the diagnostic utility of FIB-4 among NAFLD patients with different liver fibrosis severities. PATIENTS AND METHODS: A cross-sectional study was conducted at An-Najah National University Hospital (NNUH) in Palestine. The FIB-4 index was calculated using laboratory data for 128 NAFLD patients who underwent liver biopsies between November 2014 and July 2022. The results of FIB-4 were compared with the Scheuer scoring system of liver biopsies (using F0, F1+F2, F3+F4) to determine the sensitivity and specificity of FIB-4 in detecting and staging liver fibrosis. RESULTS: Out of 128 patients involved in our study, 49 of them had advanced fibrosis according to liver biopsy (F3+F4), where their FIB-4 indices showed 87% sensitivity at 1.45 cut off point and 87% specificity at 3.25 cut off point. CONCLUSIONS: The FIB-4 index may be used as a screening tool in the primary care setting. To raise awareness of liver diseases, this non-invasive, inexpensive, simple, and quick marker could identify people in need of further liver fibrosis evaluation and diagnosis. [ABSTRACT FROM AUTHOR]
- Published
- 2024
4. In vitro Assessment of the Food Preference and Toxicity of Five Insecticides against The Land Snail Eobania vermiculata (Gastropoda; Helicidae).
- Author
-
Al-Harbi, R. K., Ismail, A. M., Bashandy, A. S. M. E., Awwad, M. H., Raddy, H. M., and Korrat, E. E. E.
- Subjects
FOOD preferences ,INSECTICIDES ,ASPARTATE aminotransferase ,CHLORANTRANILIPROLE ,GASTROPODA ,AGRICULTURAL pests ,NON-target organisms - Abstract
The land snail Eobania vermiculata is one of the most cosmopolitan and harmful agricultural pests, causing economic devastation to many crops. For this purpose, the choice and non-choice methods was used to determine the palatability of certain plants for E. vermiculata. Moreover, the vulnerability of the snail was assessed via its exposure to five common insecticides (spirotetramat, sulfoxaflor, chlorantraniliprole, spinetoram and fipronil) using leaf-dipping technique under laboratory conditions. The median lethal dose was determined for each compound while biomarkers, such as enzymatic activity levels of AST, ALT, total protein TP, and lipid TL were used to evaluate sublethal effects. The findings of the no-choice feeding trial revealed that E. vermiculata significantly consumed a higher amount of Lactuca scariola var. sativa leaves compared to other tested plants. Cichorium cicorea leaves were found to be the least preferred by E. vermiculata, with an average of 1.71 g after 5 days. On the other hand, the results of the free choice feeding trial revealed that L. scariola var. sativa and Brassica oleracea leaves were the most frequently consumed by E. vermiculata. Conversely, E. vermiculata exhibited the lowest preference towards Brassica rapa leaves. The results of the molluscicidal activity indicated that the mortality rate is dose-dependent. After one month of exposure to a concentration of 1,000 ppm per 100 mL, chlorantraniliprole caused 46.4% mortality, followed by sulfoxaflor and fipronil, which exhibited equal mortality values of 42.9%. The latter insecticides revealed LC
50 of 1,010.5, 2,501.9, and 1,444.7 ppm per 100 mL against E. vermiculata, respectively. Nevertheless, spinetoram and spirotetramat caused a lower mortality rate for E. vermiculata. The biochemical analysis results showed that the activities of alanine aminotransferase (ALT), aspartate aminotransferase (AST), total proteins (LP), and the lipid profile of E. vermiculata have increased by 50% in response to the insecticides. Compared to the control and other compounds, spirotetramat increased total cholesterol by 33 mg dL-1 . The activity of ALT, AST, and triglycerides decreased after the application of spinetoram and fipronil treatment, with values reaching 13 u L-1 , 32 u L-1 , and 4 mg dL-1 of TL, respectively. However, no substantial effects of insecticides were observed on TP, Total cholesterol, LDH, or LP levels after the exposure period. The study's findings indicate that chlorantraniliprole, a novel insecticide group, could be a promising approach for controlling the land snail E. vermiculata. Unlike other, more hazardous insecticides, chlorantraniliprole has not previously been used to control snails. Furthermore, it appears to be safe for non-target organisms and mammals, making it an excellent choice for snail management. [ABSTRACT FROM AUTHOR]- Published
- 2024
- Full Text
- View/download PDF
5. Prevalence of Helicobacter pylori resistance to certain antibiotics at An-Najah University Hospital: a cross-sectional study.
- Author
-
Abdoh Q, Alnees M, Kharraz L, Ayoub K, Darwish A, Awwad M, Najajra D, Khraim J, Awad W, Sbaih A, Turman S, and Abu Hamdeh N
- Subjects
- Humans, Female, Male, Cross-Sectional Studies, Adult, Prevalence, Middle Aged, Drug Resistance, Bacterial, Hospitals, University, Microbial Sensitivity Tests, Amoxicillin therapeutic use, Amoxicillin pharmacology, Clarithromycin therapeutic use, Clarithromycin pharmacology, Metronidazole therapeutic use, Metronidazole pharmacology, Levofloxacin therapeutic use, Levofloxacin pharmacology, Helicobacter pylori drug effects, Helicobacter pylori isolation & purification, Helicobacter Infections drug therapy, Helicobacter Infections microbiology, Helicobacter Infections epidemiology, Anti-Bacterial Agents therapeutic use, Anti-Bacterial Agents pharmacology
- Abstract
Antibiotic resistance among bacteria is recognized as the primary factor contributing to the failure of treatment. In this research, our objective was to examine the prevalence of antibiotic resistance in H. pylori bacteria in Palestine. We enlisted 91 individuals suffering from dyspepsia, comprising 49 females and 42 males. These participants underwent esophagogastroduodenoscopy procedures with gastric biopsies. These biopsies were subsequently subjected to microbiological assessments and tested for their susceptibility to various antimicrobial drugs. Among the 91 patients, 38 (41.7%) exhibited the presence of H. pylori. Notably, Ciprofloxacin displayed the highest efficacy against H. pylori, followed by Levofloxacin, Moxifloxacin, and Amoxicillin, with resistance rates of 0%, 0%, 2.6%, and 18.4%, respectively. On the contrary, Metronidazole and Clarithromycin demonstrated the lowest effectiveness, with resistance percentages of 100% and 47.4%, respectively. The outcomes of this investigation emphasize that H. pylori strains within the Palestinian patient group exhibit substantial resistance to conventional first-line antibiotics like clarithromycin and metronidazole. However, alternative agents such as fluoroquinolones and amoxicillin remain efficacious choices. Consequently, we recommend favoring quinolone-based treatment regimens for H. pylori infections and adopting a more judicious approach to antibiotic usage among the Palestinian population., (© 2024. The Author(s).)
- Published
- 2024
- Full Text
- View/download PDF
6. The knowledge regarding the impacts and management of black triangles among dental professionals and laypeople.
- Author
-
Al-Omiri MK, Atieh DWA, Abu-Awwad M, Al Nazeh AA, Almoammar S, Hassan SAB, Aljbab AA, Alfaifi MA, Shat NM, and Lynch E
- Subjects
- Humans, Male, Female, Adult, Cross-Sectional Studies, Surveys and Questionnaires, Students, Dental psychology, Young Adult, Middle Aged, Dentists psychology, Health Knowledge, Attitudes, Practice
- Abstract
This study aimed to assess the knowledge regarding impacts, causes and management of black triangles (BT) among participants from different educational backgrounds including dental students, dentists and laypeople. This descriptive cross-sectional observational research included 435 participants who comprised 4 groups: pre-clinical (3rd year) dental students, clinical (4th and 5th year) dental students, dentists, and laypeople. A constructed self-reported questionnaire was utilized to assess participants' demographic data and their knowledge of the impacts, causes and management of BT. The VAS scale was used to assess participants' ratings for the impacts of BT on esthetics, with 0 meaning no impact and 10 meaning very severe negative impacts. The most reported treatments for BT were "cannot be treated" 99.3% and "non-surgical periodontal treatment" 67.1%. Meanwhile, the least reported was "modify the porcelain" 41.8%. The most reported cause of BT was "periodontal disease" 85.1%. However, the least reported were "parafunction" and "deep implants" 33.1% each. Dental professionals had better knowledge of the causes (t = 8.189, P < 0.001) and management (t = 8.289, P < 0.001) of BT than the non-dental participants. The dentists had the best knowledge, while the laypeople had the least knowledge of the causes (F = 62.056, P < 0.001) and treatment (F = 46.120, P < 0.001) of BT. The knowledge of the causes (t = 0.616, P = 0.538) and treatment (t = 1.113, P = 0.266) for BT was not significantly different between males and females. Age was not significantly related to the total knowledge about the causes (r = -0.034, P = 0.475) or treatment (r = -0.034, P = 0.482) for BT. Dental professionals had better knowledge of the impacts, causes and management of BT than the non-dental participants. The dentists were the best, while the laypeople were the worst in this regard. Age and gender had no relationships with the knowledge of causes or management of BT., (© 2024. The Author(s).)
- Published
- 2024
- Full Text
- View/download PDF
7. Complete denture palatal rugae design impact on satisfaction and quality of life.
- Author
-
Abu-Awwad M, Bustani M, Alkababji M, Majdalawi F, Salim NA, and Al-Omiri MK
- Abstract
Objectives: To compare the impact of three complete denture palatal rugae designs on participants' satisfaction and oral-health-related quality of life., Background: Complete dentures palatal rugea are usually polished to a smooth finish, which can affect the patient's adaptation. Roughening or keeping an opening in the rugae area to replicate the natural sensation of the palatal rugae has been suggested but lacks clinical evidence., Methods: This randomised crossover trial included participants with complete dentures randomly allocated to six sequences. Each sequence alternated between polished, roughened, and open rugae designs. Participants evaluated general and domain-specific satisfaction (eating, taste, speaking, phonetics, and ease of cleaning) on a 100-mm visual analogue scale. They also completed the Oral Health Impact Profile for Edentulous Patients (OHIP-EDENT) and indicated their preferred design at the end. Repeated-measure ANOVA compared satisfaction, and one-way ANOVA with Tukey's test compared OHIP-EDENT scores., Results: Forty-two participants were randomised. Seven dropped out. General satisfaction ratings were comparable for the polished (Mean = 80.2, SD = 19.7) and roughened designs (Mean = 79.5, SD = 20.2). However, the open design had a significantly lower satisfaction rating (Mean = 41.1, SD = 32.2). OHIP-EDENT scores for the open design (Mean = 44.9, SD = 17.5) were significantly worse than those for the polished (Mean = 36.1, SD = 12.7) and roughened designs (Mean = 36.2, SD = 13.3). Two-thirds of the participants chose the polished design. One-third chose the roughened design; of those, 83% were first-time denture wearers., Conclusions: Complete dentures with polished and roughened rugae designs were perceived similarly. Both designs could be recommended based on the patient's preference. However, the open design should be avoided due to negative perception., (© 2024 Gerodontology Association and John Wiley & Sons Ltd.)
- Published
- 2024
- Full Text
- View/download PDF
8. A rare delayed onset of esophageal varices and portal vein thrombosis in a ten-year-old patient following umbilical vein catheterization.
- Author
-
Abdoh Q, Darwish A, Alnees M, Awwad M, Najajra D, Alsadi M, and Alawneh M
- Abstract
Introduction and Significance: Portal vein thrombosis (PVT) is not commonly observed in patients, particularly those who have gone through neonatal intensive care unit (NICU) stays and had umbilical catheters. Although PVT can potentially cause hypertension and gastrointestinal bleeding it is highly unusual for this condition to manifest during childhood., Case Presentation: The authors present a case of a 10-year-old child who developed portal hypertension, esophageal varices, and multiple thrombophilia associated mutations. This child was born prematurely. Had to stay in the NICU, where an umbilical venous catheter was used which likely triggered the development of PVT. At the age of 7 he started experiencing distension, anemia and low platelet count, which eventually led to splenectomy. On at the age of 10 he began experiencing episodes of bleeding. Was diagnosed with esophageal varices and portal gastropathy. Through procedures, like Histoacryl glue injection and band ligation bleeding was successfully controlled. Genetic analysis revealed mutations associated with thrombophilia., Clinical Discussion: This case highlights how rare it is for older children to develop PVT and emphasizes the possibility of delayed onset symptoms following catheterization. The placement of catheters in NICUs can disrupt blood flow and increase the likelihood of clot formation. The presence of hypertension resulting from PVT can lead to complications such as varices. Effective control, over bleeding was achieved through interventions.Importantly, the presence of ACE I/D, FXIII Val34Leu, and Factor V Leiden mutations introduces an aspect to this scenario. It is worth noting that these mutations are not commonly linked to thrombophilia or clotting disorders., Conclusion: This case highlights pediatric PVT, emphasizing the need for a collaborative approach among gastroenterologists, hematologists, and geneticists. Further research is required to understand PVT mechanisms and long-term implications, aiding in diagnosis and management, especially when it appears in late childhood. Evaluation is crucial in deciphering thrombophilia-related complications in the context of hypertension., Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.Sponsorships or competing interests that may be relevant to content are disclosed at the end of this article., (Copyright © 2024 The Author(s). Published by Wolters Kluwer Health, Inc.)
- Published
- 2024
- Full Text
- View/download PDF
9. Simplified versus conventional complete dentures: A randomized crossover clinical trial.
- Author
-
Ereifej NS, Oweis YG, El Manaseer W, Al Omoush S, Abu Awwad M, and Sartawi S
- Subjects
- Humans, Denture, Complete, Patient Satisfaction, Mastication, Quality of Life, Denture Retention, Mouth, Edentulous
- Abstract
Statement of Problem: A simplified approach to complete denture treatment, omitting the border molding and definitive impression appointment, was suggested as an alternative to the conventional approach. However, comparison clinical trials are lacking., Purpose: The purpose of this randomized crossover clinical trial was to assess the satisfaction of edentulous patients and their oral health impact profile when provided with complete dentures fabricated through the simplified or the conventional approach., Material and Methods: Forty completely edentulous patients seeking complete dentures were randomly divided into 2 groups (n=20). Each group received 2 sets of dentures. The first group received conventionally fabricated complete dentures, and the second group received complete dentures fabricated through the simplified approach. After 2 months, participants rated their overall satisfaction and their satisfaction regarding comfort, retention, stability, and efficiency of mastication and speech on a 100-mm visual analog scale (VAS). Participants also filled out the oral health impact profile for edentulous patients (OHIP-EDENT) questionnaire. Each group was then given the alternate set of dentures and reviewed again after 2 months. The results were analyzed by using the Mann-Whitney U and Wilcoxon-signed rank tests (α=.05)., Results: The simplified complete dentures had significantly higher VAS scores for general satisfaction with maxillary dentures (P=.036), satisfaction with retention of maxillary dentures (P=.002), satisfaction with stability of maxillary dentures (P=.003), and satisfaction with speaking (P=.002). No statistically significant differences were found between the 2 groups regarding the other VAS items or OHIP-EDENT scores (P>.05)., Conclusions: The simplified denture fabrication approach required fewer appointments and resulted in higher patient satisfaction and similar OHIP-EDENT scores compared with the conventional approach. The simplified approach can be recommended over the conventional approach., (Copyright © 2022 Editorial Council for the Journal of Prosthetic Dentistry. Published by Elsevier Inc. All rights reserved.)
- Published
- 2024
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.