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Understanding the predictor of learning achievement among college students is crucial to adopting the appropriate learning strategy. Academic buoyancy is one of the predictors of learning achievement, playing a vital role in helping students navigate academic setbacks and adversities. However, the previous studies failed to reveal a robust link between the two variables. Therefore, this study aims to explain the nexus between academic buoyancy and students' learning achievement more clearly by introducing the mediating variable, motivational constructs, which include selfefficacy, persistence, and anxiety. This study involved 493 college students in Indonesia. Structural equation modeling (SEM) was utilized to examine the research hypotheses. The results show that academic buoyancy directly affects learning achievement. Furthermore, motivational constructs (self-efficacy, persistence, and anxiety) significantly mediate the relationship between academic buoyancy and learning achievement. This study contributes to the literature by explaining how academic buoyancy affects learning achievement through motivational constructs as a mediating variable. Furthermore, the university must promote students' academic buoyancy and motivational constructs by providing counseling services and encouraging students to recognize and address the adversities during lecture activities.

The flipped classroom (FC) and case-based learning (CBL) are recognized as effective instructional models that emphasize the development of problem-solving ability. However, the implementation of FC combined with CBL has not been well explored. This study aims to investigate the effect of FC combined with CBL on students' problem solving by comparing it with the FC model and the traditional method. Three groups in a private university in Indonesia participated in an experimental study involving 94 students. Across 8 weeks, one experimental group received the FC model and a second experimental group received FC combined with the CBL model. The control group received regular learning activities. A measure of problem-solving ability was administered to all groups before and after the 8-week intervention. In the FC combined with CBL model, problem-solving ability increased significantly compared to students in the control group. The findings need to be replicated with an extended, after-class session that involves larger groups of participants over a longer time period.

Students are required to have the ability to implement mathematics in solving everyday life problems. A good solving process will produce an excellent solving ability. The existing problem-solving stages cannot be used in solving problems with the Higher Order Thinking Skills (HOTS) category. The aims of this research are 1) to know students' problem-solving process in solving HOTS category questions; 2) to design the stages of problem-solving that can be used to solve HOTS category questions. Twenty-four students who took the differential calculus course in mathematics education at one of Indonesia's private universities made up the study group. The solving process is divided into high, medium, and low. The descriptive and qualitative research method describes the Polya stages' problem-solving approach. Researchers used four sets of problem-solving by making nine indicators. Based on the analysis results, it can be concluded that several indicators of the problem-solving stages have not been appropriately implemented, including I4, I8, and I9. In addition, the steps at the Polya problem-solving stage of devising a plan and looking back must be improved. Based on the findings above, research recommendations design the stages of problem-solving consisting of 6 steps. Future research will develop steps of problem-solving with the characteristics of the HOTS category questions.

One of the Information and Communication Technology (ICT) developments used in the learning process is the Intelligent Tutoring System (ITS), and gamification can overcome boredom, lack of interest or motivation, and monotony when using the ITS. In this study, the application of ITS equipped with Gamification is called ITS + G. Currently, several studies have built the ITS + G. However, there has not been a Systematic Literature Review (SLR) that synthesizes the characteristics of the ITS and Gamification combination. Several previous SLRs have been carried out and discussed the ITS only and several other SLRs discussed gamification only. Therefore, this SLR focused on the characteristics of ITS and gamification as a unit. This study succeeded in synthesizing that ITS + G has the potential to be applied to both STEM and non-STEM subjects. Three main game elements are mostly used in ITS + G: levels, points, and progress bars, which are supported for several reasons. Several techniques that have been used to measure the success of ITS + G are synthesized. Several positive impacts of ITS + G are revealed. Some negative impacts that need to be considered and studied in future research are also noticed. The results of this study could be the basis for ITS + G research in the future and increase the repertoire of knowledge related to ITS and Gamification.

The rapid progress in information technology has presented both opportunities and challenges for companies, particularly within the IT industry in Indonesia. This study examines the impact of hybrid business strategies and corporate strategic alliances on the sustainability performance of IT companies. Adopting quantitative methods, data were collected from 389 management professionals in IT companies through a structured questionnaire. The analysis employed structural equation modeling (SEM) to assess the relationships between hybrid business strategies, strategic alliances, and sustainability performance. The results indicate that hybrid business strategies positively influence corporate strategic alliances (t-value = 2.243, p-value = 0.025) and positively influence corporate sustainability performance (t-value = 5.294, p-value = 0.000). Additionally, corporate strategic alliances significantly enhance sustainability performance (t-value = 5.603, p-value = 0.000), mediating the relationship between hybrid strategies and sustainability outcomes (t-value = 1.995, p-value = 0.047). The findings emphasize the critical role of strategic alliances in achieving long-term sustainability goals in the IT industry. The study concludes that integrating hybrid business strategies with effective strategic alliances is essential for IT companies to maintain competitiveness and achieve sustainable growth.

Telah banyak dilakukan penelitian mengenai Moodle, LMS terkenal, dan pengaruhnya terhadap berbagai aspek pendidikan. Akan tetapi, terdapat kekurangan yang signifikan dalam literatur mengenai penggunaan Moodle secara spesifik untuk meningkatkan kemampuan menulis teks eksposisi. Penelitian ini untuk mengetahui bagaimana pemahaman dan kemampuan siswa menulis teks eksposisi dan bagaimana penggunaan Moodle dalam meningkatkan kemampuan menulis teks eksposis. Melalui metode penelitian literatur review, penulis memilih 2 artikel dari 19 artikel terkait Moodle dan memilih 6 artikel dari 18 artikel terkait penulisan teks eksposisi untuk dianalisa. Dari hasil penelitian ini, siswa mampu menulis teks eksposisi dengan baik dengan pemahaman yang baik juga. Di samping itu, penggunaan Moodle dapat meningkatkan kemampuan menulis siswa bahasa Inggris. Penggunaa Moodle lebih efektif daripada metode konvensional dalam meningkatkan kemampuan menulis siswa, dengan hasil yang menguntungkan kelompok eksperimen. Implikasinya adalah peneliti lain bisa meneliti dampak penggunaan Moodle untuk meningkatkan kemampuan teks eksposisi di sekolah dasar.

Permainan anak-anak merupakan tradisi turun-temurun yang dilakukan masyarakat di Indonesia, termasuk di Madura. Salah satu jenis permainan tradisional tersebut ialah yang berbentuk lagu permainan anak-anak. Lagu permainan anak “Lar Olar Kolarjhang” merupakan lagu tradisional yang dimiliki oleh Masyarakat Madura. Lagu permainan anak “Lar-Olar Kolarjang” ini mirip atau memiliki nama lain di daerah-daerah yang lain. Adapun nama-nama tersebut antara lain Wak Wak Gung (Jakarta), Slepdur (Sulawesi Utara), Ancak-Ancak Alis (Jawa Tengah), Sledor (Jawa Timur), Oray-Orayan (Jawa Barat), Curik-Curik (Bali), Toko-Toko Dian (Palopo, Sulawesi Selatan). Lagu ini memiliki nilai filosofis yang dipegang teguh dan diwariskan secara turun temurun dari generasi ke generasi. Adapun nilai-nilai tersebut yakni nilai kebersamaan, nilai penghargaan terhadap diri sendiri dan orang lain, serta nilai kepemimpinan baik bagi diri sendiri maupun orang lain. Nilai-nilai inilah yang menjadikan lagu permainan anak “Lar Olar Kolarjhang” perlu untuk dilestarikan dan diajarkan ke generasi muda agar dijadikan pegangan hidup, baik secara khusus bagi masyarakat Madura maupun masyarakat luas lainnya di Indonesia.

Genome editing through cisgenesis develops into scientific breakthroughs in accelerating oil palm breeding programs. However, one remaining problem is the low success of transformed-calli regeneration, while its scientific explanation is still underexplored. This study aimed to characterize and regenerate transformed-calli using various amino acids and antioxidants. Transformed callus that did not regenerate (un-regenerated transformed callus or UTC) after the transformation process was taken, then T-DNA integration was detected using the NPTII gene. Furthermore, the UTC was divided into four types based on morphological characteristics. The four types of UTCs were regenerated on media enriched with glutamine (for Type-1 callus), cysteine and putrescine (for Type-2 callus), and a combination of cysteine and ascorbic acid (for Type-3 and Type-4 callus). The research results obtained NPTII successfully amplified with a band size of 700bp. The results showed that on Type-1 callus, enrichment media with 10 mg L-1 L-glutamine could induce the formation of new nodular structures on UTC Type-1. On Type-2, media enriched with 5 mg L-1 L-cysteine + 20 mg L-1 putrescine increased the density of callus structures. Media enriched with 25 mg L-1 ascorbic acid + 25 mg L-1 L-cysteine could prevent the spread of brown callus on Type-3 callus, while Type-4 callus did not show any response and became dry. Our new findings will facilitate the basic research and unregenerated transformed callus and morphological callus development behavior in oil palm.

One of the MSMEs developed Batik as a regional product is Rezti's Batik. Rezti's Batik is located in Ambulu, Jember Regency, about 28.4 km from the University of Jember. Increasing the number of consumer orders has made Rezti's Batik production continue to increase. One of the obstacles faced by Rezti's Batik is the process of making Batik which takes a long time because the drying process still relies on heat from the sun, which takes 4-6 hours. The process can also take longer if the rainy season slows the production process's completion. The solution method is the manufacture of appropriate technology in the form of installing a batik cloth dryer. The batik cloth drying installation implementation at Rezti's Batik is a drying system that utilizes heat from the furnace in the sagging process as a heating medium. The designed dryer consists of a stove as a heat generator which will later be distributed with air from the blower so that the hot air will spread evenly throughout the room.

Aim: Assessing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) immunoglobulin G (IgG) antibodies among healthcare workers (HCWs) is crucial in understanding the durability of humoral immune response due to vaccination and the post-pandemic era. Therefore, this study aimed to evaluate IgG antibody seroprevalence, IgG levels, and long-term durability responses after the coronavirus disease 2019 (COVID-19) pandemic in HCWs. Methods: The cross-sectional study recruited HCWs aged ≥ 18 years, vaccinated at least once, and without autoimmune diseases at Dr. Wahidin Sudirohusodo Hospital Makassar. Antibody titers against spike protein, nucleocapsid protein, and spike-nucleocapsid conjugate were quantified using dried blood spot (DBS) samples and multi-antigen profiling (xMAP) technology to measure seroprevalence. Results: The results showed that there was a total of 103 participants with the majority being female (59.22%), ≤ 40-year-old (87.38%), nurses (56.31%), had no comorbidities (88.35%), and were infected with COVID-19 (70.87%). A significant proportion received three times vaccination (76.7%), while 102 of 103 (99.03%) showed seropositivity. IgG showed the highest mean antibody titers for spike protein [10,819.38 ± 2,554.23 mean fluorescence intensity (MFI)] in the first 6–12 months after the last vaccinations. Meanwhile, the IgG titer (MFI) showed a long duration over 30 months. Vaccine significantly influenced spike protein antibody levels, with the highest observed in the group receiving a combination of two inactivated vaccines followed by two messenger ribonucleic acid (mRNA) vaccines (p < 0.05). Conclusions: HCWs showed a sustained humoral immune response to SARS-CoV-2 for over 24 months post-vaccination. The type and combination of vaccines administered were significantly correlated with the IgG antibody levels, suggesting the long-term efficacy of the vaccination regimens. The application of DBS and xMAP technology in the study facilitated the assessment of SARS-CoV-2 IgG responses, offering valuable insights into the dynamics of immune persistence following vaccination.

BACKGROUND: The current biomarker diagnostic modality for acute coronary syndrome (ACS), cardiac troponin, has several limitations. Emerging studies showed that micro-RNA (miR)-133a was released from infarcted heart to circulation, yet the diagnostic value of miR-133a in ACS demonstrated a conflicting result. Therefore, this study was conducted to investigate the potency of plasma miR-133a as a biomarker candidate of ACS. METHODS: This was a case-controlled study, involving ACS and control subjects. The sociodemographic and clinical characteristics were assessed through medical records. A final of 39 ACS and 31 control subjects (consist of healthy and non-ACS subjects) passed the selection procedure by demonstrating a high purity of RNA. miR-133a from ACS and control subjects were detected by quantitative polymerase chain reaction (qPCR). Expression of miR-133a was evaluated for sensitivity and specificity as an ACS biomarker diagnostic using the receiver operating characteristic (ROC) curve. RESULTS: Plasma miR-133a expression was stably found in ACS subjects. The plasma miR-133a level was lower in ACS than in control subjects. miR-133a effectively distinguished ACS subjects from healthy subjects (AUC=0.911) and exhibited high diagnostic performance, with a sensitivity of 87.1% and specificity of 100% at a cut-off value of 44.035. In an extended model including both control subjects (healthy and non-ACS with comorbid conditions), miR-133a maintained diagnostic significance (AUC=0.874), showing sensitivity of 76.9% and specificity of 100% at a cut-off value of 11.69. CONCLUSION: Plasma miR-133a is significantly lower and effectively distinguishes ACS patients from both healthy individuals and non-ACS individuals with comorbid, with a cut-off value of 11.69. Therefore, plasma miR-133a is suggested to be a good candidate for diagnostic biomarkers of ACS. KEYWORDS: circulating miRNA, miRNA-133a, acute coronary syndrome, diagnostic biomarker

Sustainable fishing ports play a vital role in ensuring the long-term health of marine ecosystems and supporting the livelihoods of coastal communities. This article explores the factors that contribute to the development of sustainable fishing ports, which consider environmental, social, and economic aspects in a balanced way. This research aims to develop a model of sustainable fishing port considering significant factors which influenced the sustainable fishing port, especially for fishing ports located in East Java Province, Indonesia. In this term, the sustainable fishing port is well known as an eco-fishing port. Purposive sampling was used to choose 215 participants from representatives of the government, private sectors in the fishing field, and fishing communities of six potential fishing ports in East Java Province, Indonesia. The data was analysed using a partial least square (PLS) approach with SmartPLS 3. The findings of the research indicate that eight hypotheses (H1, H2, H3, H4, H5, H7, H8 and H11) are supported while three hypotheses (H6, H9, and H10) are not supported. The study reveals a significant correlation between market demand, community welfare, infrastructure, environmental carrying capacity, and regulation. It is also found that market demand, community welfare, infrastructure, environmental carrying capacity, and regulation have significant positive relations with eco-fishing ports. The positive relationship indicates that adherence to these regulations fosters responsible fishing methods, preventing overexploitation of fish stocks, and contributes to the conservation of marine environments, ensuring the port operates in harmony with natural ecosystems and local communities.

Abstract Background As identified by the research, it is imperative to develop effective ways to address the pressing problem of disease and pest susceptibility in chili agriculture and secure sustainable crop yield. The research examines the impact of various growing microclimates, watering regimens, and chili cultivars on disease incidence, pest attacks, and yield loss. Results The study, which took place over a season, used a randomized complete block design to evaluate how well Tanjung, Unpad, and Osaka cultivars performed in four different watering regimens (100, 75, 50, and 25% ETc) and different microclimates (greenhouse, rain shelter, screen house, and open field). The findings exhibited that watering regimens and microclimates greatly influenced disease and pest occurrence, but cultivars had a minimal effect on these variables. Disease and pest attack rates were highest in the open field and lowest in the screen house. A correlation was found between lower disease and pest incidence and optimal irrigation levels (75% and 100% ETc). At lower watering regimens of 25% ETc and in the open field, yield loss was the greatest. Conclusion The results emphasize how crucial controlled environments and appropriate irrigation techniques are to reducing crop loss and increasing production. Enhancing watering regimens and implementing screen house cultivation are two strategies for improving the productivity and sustainability of chili output.

Processing lamb meat into fermented sausages can reduce the risk of spoilage and extend shelf life. Fermented sausages are commonly made using lactic acid bacteria (LAB), resulting in a product that is acidic and less firm. Therefore, it is necessary to add jack bean flour as a binding agent. This study aims to analyze physicochemical, microbiological and organoleptic characteristics of premium IPB lamb fermented sausages with varying proportions of jack bean flour (0% and 30%). The analyses included pH, water activity (aw), total acid, water, ash, fat, crude protein, carbohydrate, total LAB, E. coli, S. aureus, texture profile analysis (TPA), and sensory evaluation. The incorporation of jack bean flour into lamb meat fermented sausages can elevate the pH, springiness, chewiness, crude protein, and carbohydrate content of the fermented sausages. Furthermore, the addition of jack bean flour may reduce the total acid, aw, gumminess, water content, and bacteria (E. coli and S. aureus). The sensory aspects such as color in fermented sausage with addition of jack bean flour were preferred by the panelists. The addition of jack bean flour increased the total unsaturated fatty acids and essential amino acids in fermented sausages. The incorporation of jack bean flour aligns with the Indonesian National Standards for Meat Sausages 3820–2015 concerning moisture, fat, and protein content. This study suggests that incorporating lamb fermented sausage with 30% jack bean flour could result in significant benefits, including increased nutrition, enhanced sensory quality, improved texture, and extended storage life for fresh lamb products.

The high level of public interest in using the Solo-Jogja commuter needs to be accompanied by an effort to improve the services and reliability of facilities, one of which is the establishment of a Commuter Depot located at Solojebres Station. In the 18th month of work, the construction of the Commuter Depot experienced delays in work performance with a deviation between plan progress and actual progress of -3.5415%. This research aims to evaluate project performance, including the project's cost and schedule performances, and estimate the cost and schedule of the project at completion due to delays that occur using the Earned Value Method with a fuzzy approach. The required data are the Budget Plan, Weekly Project Report, S-curve, and Actual Cost data. Based on the analysis result, until the 18th month of work, obtained the total Planned Value of IDR 64,581,925,585 (simplified to IDR 6,458.2), the total Actual Cost of IDR 63,954,955,399 (simplified to IDR 6,395.5), the total Fuzzy Earned Value of IDR 62,740,381,379.42 (simplified to IDR 6,274.0), the Cost Performance Index indicates that the project is ahead of budget condition, the Schedule Performance Index indicates that the project is behind schedule condition, the Cost Estimate at Completion of IDR 96,048,508,686 with the cost needed to complete the rest of work of IDR 32,093,553,287 and the Schedule Estimate at Completion of 27.03 months with the time required to complete the rest of work of 9.03 months.

Background: Indonesia has successfully eradicated wild poliovirus since 2005 using robust immunization and AFP surveillance programs. However, circulating vaccine-derived poliovirus type 2 has challenged these commitments, followed by the 2024 outbreak in East Java. Purpose: The study aims to analyze the polio eradication initiative by assessing polio immunization coverage and AFP surveillance in East Java. Methods: A descriptive, quantitative study design and retrospective analysis of polio immunization coverage and AFP surveillance indicators from the Provincial Health Office, East Java, from 2018–2022. The data was collected and analyzed using Excel, EpiInfo7, and Health Mapper software. Results: OPV4 coverage ranged from 89.95% to 100.76%, while IPV coverage ranged from 73.98 % to 94.18% from 2018 to 2020; the proportion of districts and cities for IPV coverage increased from 0% in 2018 to 44.74% in 2022, below the 95% WHO target. Of the 826 cases of AFP reported, 820 (99.27%) were actual AFP cases

Environmental concern is a determinant in acquiring new green innovation. We aimed to investigate the relationship between environmental concern, consumer attitude, and behavioral intention to switch in the context of drone delivery. The motivation that comes from a green perspective is believed to create a behavior that is also keen on innovative green products. One of the examples is the implementation of drones in delivering parcels, which is believed to cut the carbon footprint. Our purpose was to analyze the direct impact of environmental concern on consumers' behavioral intentions regarding e-commerce drone delivery. Additionally, we aimed to examine the mediating role of consumers' attitudes toward innovation in the relationship between environmental concern and behavioral intention. We sought to provide insights into how environmental awareness and the adoption of innovative delivery technologies like drones can influence consumer behavior, contributing to more sustainable and eco-friendly e-commerce practices. Structured questionnaires were provided to e-commerce users, reliability and validity tests were confirmed, and structural equation modeling (SEM) was used to analyze the relationships among variables. The results of the SEM analysis proved that environmental concern and consumer attitudes have a positive impact on behavioral intention. Customer attitude mediates the relationship between environmental concern and behavioral intention. This research provides a deeper understanding of how environmental concerns influence consumer behavior towards drone delivery innovation within the e-commerce sector. The implications integrate environmental concerns with consumer behavior and innovation adoption, providing a comprehensive view that goes beyond traditional marketing and consumer research.

Abstract Microsatellite instability (MSI) occurs across a number of cancers and is associated with different clinical characteristics when compared to microsatellite stable (MSS) cancers. As MSI cancers have different characteristics, routine MSI testing is now recommended for a number of cancer types including colorectal cancer (CRC). Using gene panels for sequencing of known cancer mutations is routinely performed to guide treatment decisions. By adding a number of MSI regions to a small gene panel, the efficacy of simultaneous MSI detection in a series of CRCs was tested. Tumour DNA from formalin-fixed, paraffin-embedded (FFPE) tumours was sequenced using a 23-gene panel kit (ATOM-Seq) provided by GeneFirst. The mismatch repair (MMR) status was obtained for each patient from their routine pathology reports, and compared to MSI predictions from the sequencing data. By testing 29 microsatellite regions in 335 samples the MSI status was correctly classified in 314/319 samples (98.4% concordance), with sixteen failures. By reducing the number of regions in silico, comparable performance could be reached with as few as eight MSI marker positions. This test represents a quick, and accurate means of determining MSI status in FFPE CRC samples, as part of a routine gene mutation assay, and can easily be incorporated into a research or diagnostic setting. This could replace separate mutation and MSI tests with no loss of accuracy, thus improving testing efficiency.

The purpose of this study is to test and implement the feasibility of Augmented Reality (AR) media in social studies learning that has been designed in previous research, as well as develop an implementation strategy. Augmented Reality (AR) learning media focuses on teachers and students in the classroom in social studies learning. Meanwhile, AR media helps teachers contextualize social studies learning and can be used as a source of social studies learning Quantitative research approaches use research designs and methods, namely through product testing or socialization, the level of effectiveness using pseudo-experiments in three schools in Bandung City Junior High School. The study results provide information about the feasibility and testing of AR media products that are suitable for use in social studies learning. This states that 97% of students are interested in AR learning. The effectiveness of AR media applications in social studies learning obtained a very high response from students, 90%, while the responses of teachers and students showed promising results in using AR media applications in the classroom.

Background: Oocyte diameter is crucial for initiating meiosis and supporting the maturation capability, a prerequisite for successful fertilisation and high-quality embryo development. While numerous studies have explored the correlation between oocyte diameter and embryo development capacity in animal models, limited research appears concerning human oocytes. Aim: This study aims to ascertain whether oocyte diameter can serve as a reliable predictor of oocyte and embryo quality, achieved through its correlation with protein kinase B (Akt) protein levels on cumulus–granulosa cells and blastocyst morphokinetics. Setting and Design: Prospective cohort study included cumulus–granulosa cells collected from 228 mature oocytes of 32 infertile women undergoing in vitro fertilisation treatment. The diameter of the oocytes was measured using the Image J software, and the samples were categorised into three groups based on their diameter: 118.97 µm. Quantification of pAkt and Akt protein total of cumulus–granulosa cells exploited the ELISA method. Embryo morphokinetics and anomaly development events were observed at the blastocyst stage to evaluate embryo quality relative to oocyte diameter. Statistical Analysis Used: The Kruskal–Wallis test and Chi-square test were used. P 0.05). Likewise, there were no significant differences in morphokinetics and anomaly development except for the S2 parameter and reverse cleavage. Conclusion: Reflecting on the molecular profile including pAkt, total Akt protein, morphokinetics and anomaly development, it was observed that oocyte diameter does not correlate with its competency and the quality of the resulting embryo. In addition, oocytes with a diameter below 105.95 µm may have an equal potential to develop into top-quality embryos.