Search

Selecting an appropriate anode material (AM) has been considered to be a crucial initial step in advancing high-performance batteries. Within this piece of research, we examine the suitability of the BC 6 NA monolayer (referred to as BC 6 NAML) as an AM by first-principles calculations. The BC 6 NAML exhibits metallic behavior consistently, even with varying concentrations of Na atoms, making it an ideal choice for battery usages. Our findings revealed that the theoretical storage capacity for Na-adhered BC 6 NAML was 406.36 mAhg -1 , surpassing graphite, TiO 2 , BC 6 NA, and numerous other 2D materials. The BC 6 NAML also demonstrates a diffusion barrier of 0.39 eV and favorable diffusivity of Na-ions. Although the open-circuit voltage (OCV) of BC6NAML was temperate and lower compared to the OCV of other AMs like TiO 2 , our results suggested that it is possible to utilize BC 6 NAML as one of the encouraging host materials for sodium-ion batteries (SIBs). Consequently, this investigation into the potential anodic application of BC 6 NAML proves valuable for future experimental studies into sodium storage for SIBs., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier Inc. All rights reserved.)

Pentylenetetrazole (PTZ)-induced kindling is a broadly used experimental model to study the anticonvulsive potential of new and existing chemical moieties with the aim of discovering drugs hindering seizure progression and associated neurological comorbidities. In the present study, the impact of brivaracetam (BRV) (10 and 20 mg/kg) as monotherapy as well as in combination with 0.25 mg/kg of perampanel (PRP) was investigated on seizure progression with simultaneous electroencephalographic changes in PTZ kindling mouse model. Subsequently, mice were experimentally analyzed for anxiety, cognition, and depression after which their brains were biochemically evaluated for oxidative stress. The outcomes demonstrated that BRV alone delayed the kindling process, but BRV + PRP combination significantly ( p < 0.0001) protected the mice from seizures of higher severity and demonstrated an antikindling effect. The PTZ-kindled mice exhibited anxiety, memory impairment, and depression in behavioral tests, which were remarkably less ( p < 0.001) in animals treated with drug combination (in a dose-dependent manner) as these mice explored central, illuminated, and exposed zones of open-field test, light/dark box, and elevated plus maze. Moreover, memory impairment was demonstrated by kindled mice, which was significantly ( p < 0.001) protected by BRV + PRP as animal's spontaneous alteration, object discrimination, and step-through latencies were increased in various tests employed for the assessment of cognitive abilities. The brains of PTZ-kindled mice had increased malondialdehyde and reduced antioxidant enzymes while treatment with BRV + PRP combination prevented kindling-induced elevation in oxidative markers. The outcomes of this study demonstrate that combining the PRP at low dose augmented the antiseizure properties of BRV as both drugs when administered simultaneously hindered the process of kindling by reducing PTZ-induced excessive electrical activity and oxidative stress in the brain., Competing Interests: The authors declare no competing financial interest., (© 2024 The Authors. Published by American Chemical Society.)

Background Undescended testis is a common pediatric surgical presentation condition with potential long-term consequences if left untreated. It is characterized by the failure of one or both testes to descend into the scrotum. This study aims to measure and enhance awareness and knowledge about undescended testis through comprehensive medical research and provide evidence-based recommendations. Objective The objective of this study was to evaluate participants' knowledge regarding undescended testes and assess the level of interest and awareness among individuals and parents about the importance of early examination and treatment. Methods It is a cross-sectional, nationwide study targeting the population of Al-Qunfudhah. The study was conducted in December 2023 using a validated questionnaire distributed through social media platforms. Results The study analyzed data from 459 participants to assess their knowledge and attitudes regarding undescended testis. Participants' knowledge was evaluated. In general, the mean ± SD score of knowledge was 3.61 ± 2.33. Higher education level, occupation, and having children were associated with greater knowledge. Attitudes were measured. The mean attitudes score was 2.37 ± 1.58. Higher education level, occupation, and marital status influenced attitudes. Conclusion This study provides valuable insights into the knowledge and attitudes of individuals regarding undescended testis. Participants displayed moderate levels of knowledge and positive attitudes, with educational attainment and occupation playing significant roles. These findings highlight the importance of targeted educational interventions to improve awareness and promote positive attitudes toward undescended testis., Competing Interests: The authors have declared that no competing interests exist., (Copyright © 2024, Taha et al.)

Atomic bandpass filters are used in a variety of applications due to their narrow bandwidths and high transmission at specific frequencies. Predominantly, these filters are in the Faraday (Voigt) geometry, using an applied axial (transverse) magnetic field with respect to the laser propagation direction. Recently, there has been interest in filters realized with arbitrary-angle magnetic fields, which have been made by rotating permanent magnets with respect to the k-vector of the interrogating laser beam. However, the magnetic field angle achievable with this method is limited as field uniformity across the cell decreases as the rotation angle increases. In this work, we propose and demonstrate a new method of generating an arbitrary-angle magnetic field, using a solenoid to produce a small, and easily alterable, axial field, in conjunction with fixed permanent magnets to produce a large transverse field. We directly measure the fields produced by both methods, finding them to be very similar over the length of the vapor cell. We then compare the transmission profiles of filters produced using both methods, again finding excellent agreement. Finally, we demonstrate the sensitivity of the filter profile to changing magnetic field angle (solenoid current), which becomes easier to exploit with the much improved angle control and precision offered by our new design., (© 2024 Author(s). All article content, except where otherwise noted, is licensed under a Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).)

Piezo-photocatalysis of ZnO nanostructures had recently well attracted due to their exceptional potential in degrading the antibiotics and scalable hydrogen production. Here, we have synthesized the Ce 3+ doped ZnO nanospheres in a facile wet chemical strategy. Dopant ions induced morphological evolution and optical bandgap tuning had observed in our experiment. Optical absorbance spectrum had confirmed the bandgap shortening occurs with Ce 3+ doped ZnO specimens. The bandgap gap value had reduced to 2.82 eV from 3.05eV confirming the visible light responsivity of ZnO nano specimens. Obtained Zn (1-x) Ce x O nanospheres were utilized to fabricate the p-Si/n- Zn (1-x) Ce x O heterojunction diodes as well studied the improved electrical conductivity for the Ce 3+ specimen-based diodes. Besides, ideality factor and barrier height values of the heterojunction diodes ZnO/p-Si, Zn 0.99 Ce 0.01 O/p-Si, Zn 0.97 Ce 0.03 O/p-Si, and Zn 0.95 Ce 0.05 O/p-Si are 15.97 & 0.43 eV, 15.47 & 0.44 eV, 8.02 & 0.46 eV and 5.21 & 0.47 eV, respectively. Direct sunlight assisted piezo-photocatalytic tetracycline (TC) degradation efficiency of ZnO, Zn 0.99 Ce 0.01 O, Zn 0.97 Ce 0.03 O, and Zn 0.95 Ce 0.05 O nanostructures respectively are 64%, 69%, 74% and 82%. We have produced the hydrogen quantity of 1234 μ mol h -1 , 1490 μ mol h -1 , 1750 μ mol h -1 and 1980 μ mol h -1 with 0%, 1%, 3% and 5% Ce 3+ doped ZnO specimens under the direct sunlight assisted piezo-photocatalytic H 2 production from H 2 S splitting., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2023 Elsevier Ltd. All rights reserved.)

Conducting polymers (CPs) are conductive materials composed of organic polymers. CPs have excellent properties such as easy synthesis and effortless fabrication, tunable electrical property, high environmental stability, high mechanical and optical properties. These unique properties have attracted researchers to discover a wide variety of uses, such as batteries, solar cells, sensors, supercapacitors, electrochromic devices, and biochemical applications. Although CPs have many limitations in their pristine form, hybridization with other materials overcomes these limitations. Here in this review article, we discuss different CPs based chemosensors for colorimetric and fluorimetric detection and determination of noble metal ions (Ag + , Pd 2+ , Pt 2+/4+ , and Au 3+ ) in different environmental, agricultural, and biological samples. Further, the sensing performances of these chemosensors have been compared and discussed. We hope this article will help the readers with the future design of CPs based optical sensor (colorimetric and fluorescent) for detecting noble metal cations.

Perampanel (PER), a novel 3rd-generation antiseizure drug that modulates altered post-synaptic glutamatergic storming by selectively inhibiting AMPA receptors, is recently approved to treat intractable forms of seizures. However, to date, presumably consequences of long-term PER therapy on the comorbid deleterious psychiatric disturbances and its correlation with neuroinflammatory parameters are not fully investigated in chronic models of epilepsy. Therefore, we investigated the real-time effect of PER on brain electroencephalographic (EEG) activity, behavioral alterations, redox balance, and relative mRNA expression in pentylenetetrazole (PTZ) induced kindling. Male BALB/c mice were pretreated with PER (0.125, 0.25, and 0.5 mg/kg) for 3 weeks and challenged with 11 injections of PTZ at the sub-threshold dose of 40 mg/kg every other day. vEEG from implanted cortical electrodes was monitored to elucidate seizure propagation and behavioral manifestations. Recorded EEG signals exhibited that PER 0.5 mg/kg pretreatment exceptionally impeded the onset of sharp epileptic spike-wave discharges and associated motor symptoms. Additionally, qEEG analysis showed that PER prevented alterations in absolute mean spectral power and reduced RMS amplitude of epileptogenic spikes vs PTZ control. Furthermore, our outcomes illustrated that PER dose-dependently attenuated PTZ-evoked anxiety-like behavior, memory deficits, and depressive-like behavior that was validated by a series of behavioral experiments. Moreover PER, significantly reduced lipid peroxidation, AChE, and increased levels of SOD and total thiol in the mice brain via AMPAR antagonism. Post-PTZ kindling provoked overstimulation of BDNF/TrkB signaling and increased release of pro-inflammatory cytokines that were reversed by PER with suppression of iNOS in brain immune cells. In conclusion, our findings highlight that PER might play an auspicious preventive role in the proepileptic transformation of brain circuits via suppression of BDNF/TrkB signaling and reduced transcriptional levels of neuroinflammatory markers leading to improvised epilepsy-induced neurobehavioral and neurochemical effects., Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (© 2023 The Author(s).)