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This study involved 48 canine individuals with ovarian cystic formations larger than 4–5.5 mm in diameter, as identified by ultrasound, who were in the diestrus or anestrus phase of the sexual cycle. Both T4 and fT4 levels were measured in all 48 cases. The imaging diagnosis of ovarian cystic formations was performed using the stationary ultrasound equipment Esaote MyLab X5, and with the owners' consent, samples were collected and the obtained data processed. Peripheral venous blood samples were collected in coagulation activator-lined tubes. Hormone assays were performed using the Biomerieux MiniVidas hormone analyzer. The results are automatically calculated by the machine using stored calibration curves and are expressed in mg/dL for T4 and in ng/dL for fT4. The objective of this study is to determine the prevalence and extent of hypothyroidism in polycystic ovarian syndrome in bitches by measuring the levels of both T4 and fT4 in 48 patients with ovarian cysts. Considering clinical symptoms, borderline values were classified as indicative of hypothyroidism. 27% (n = 13) were diagnosed with hypothyroidism, while 73% (n = 35) had euthyroidism. Statistically significant differences were found in the results of both T4 and fT4 between the euthyroid and hypothyroid groups. This study found a high prevalence of hypothyroidism in female dogs with ovarian cysts. Given the impact of hypothyroidism on ovulation in women and its potential effects in dogs, thyroid function testing is recommended for female dogs with infertility.

Veterinarians can obtain a more comprehensive understanding of the progression of ovarian cystic pathology in dogs by assessing hormonal levels. This study aimed to examine the gonadocorticoid profile of dogs diagnosed with ovarian cysts and compare these levels with those of healthy female dogs. The study included 96 female dogs split into two groups: a control group of healthy females and a study group of females with ovarian cysts larger than 4.5–5 mm in diameter and in diestrus or anestrus phase, determined by progesterone measurements. The control group had no ovarian pathologies and matched the estrus cycle phase of the study group. Ovarian cysts were diagnosed using the Esaote MyLab X5 ultrasound machine, while sex hormone levels (testosterone, progesterone, and estradiol) were measured with the Biomerieux MiniVidas analyzer. The analyzer utilizes the Enzyme Linked Fluorescent Assay (ELFA) technique for hormonal assessments. The study group (ovarian cysts) had significantly higher estradiol levels (21.83 pg/ml) compared to the control group (10.70 pg/ml). However, there was no significant difference in progesterone levels between the two groups. The study group females showed significantly higher estradiol levels in both the anestrus phase (p = 0.0105) and the diestrus phase (p = 0.0105). There was also a significant difference in estradiol levels between control group females in diestrus and anestrus, with significantly higher levels observed in the anestrus phase (p = 0.0105). In summary, female dogs with ovarian cysts had higher estradiol levels in both estrus and anestrus phases compared to the control group. The authors recommend assessing hormonal profiles in dogs with ovarian cysts for better treatment planning.