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3. Serum anti-nucleocapsid antibody level induced after primary infection is an immunological surrogate of protection against SARS-CoV-2 re-infection in hybrid immunity holders

Author

Miyamoto, Sho, primary, Numakura, Koki, additional, Kinoshita, Ryo, additional, Arashiro, Takeshi, additional, Takahashi, Hiromizu, additional, Hibino, Hiromi, additional, Hayakawa, Minako, additional, Kanno, Takayuki, additional, Sataka, Akiko, additional, Ainai, Akira, additional, Arai, Satoru, additional, Suzuki, Motoi, additional, Yoneoka, Daisuke, additional, Wakita, Takaji, additional, and Suzuki, Tadaki, additional

Published
2024
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4. The comparison of pathogenicity among SARS-CoV-2 variants in domestic cats.

Author

Park, Eun-sil, Kuroda, Yudai, Uda, Akihiko, Kaku, Yoshihiro, Okutani, Akiko, Hotta, Akitoyo, Tatemoto, Kango, Ishijima, Keita, Inoue, Yusuke, Harada, Michiko, Ami, Yasushi, Shirakura, Masayuki, Watanabe, Shinji, Suzuki, Yasushi, Harada, Toshihiko, Ainai, Akira, Shiwa, Nozomi, Sakai, Yusuke, Iwata-Yoshikawa, Naoko, and Nagata, Noriyo

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been detected or isolated from domestic cats. It is unclear whether cats play an important role in the SARS-CoV-2 transmission cycle. In this study, we examined the susceptibility of cats to SARS-CoV-2, including wild type and variants, by animal experiments. Cats inoculated with wild type, gamma, and delta variants secreted a large amount of SARS-CoV-2 for 1 week after the inoculation from nasal, oropharyngeal, and rectal routes. Only 100 TCID50 of virus could infect cats and replicate well without severe clinical symptoms. In addition, one cat inoculated with wild type showed persistent virus secretion in feces for over 28 days post-inoculation (dpi). The titer of virus-neutralizing (VN) antibodies against SARS-CoV-2 increased from 11 dpi, reaching a peak at 14 dpi. However, the omicron variant could not replicate well in cat tissues and induced a lower titer of VN antibodies. It is concluded that cats were highly susceptible to SARS-CoV-2 infection, but not to the Omicron Variant, which caused the attenuated pathogenicity. [ABSTRACT FROM AUTHOR]

Published
2024
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5. Extraction of the CDRH3 sequence of the mouse antibody repertoire selected upon influenza virus infection by subtraction of the background antibody repertoire

Author

Shingai, Masashi, primary, Iida, Sayaka, additional, Kawai, Naoko, additional, Kawahara, Mamiko, additional, Sekiya, Toshiki, additional, Ohno, Marumi, additional, Nomura, Naoki, additional, Handabile, Chimuka, additional, Kawakita, Tomomi, additional, Omori, Ryosuke, additional, Yamagishi, Junya, additional, Sano, Kaori, additional, Ainai, Akira, additional, Suzuki, Tadaki, additional, Ohnishi, Kazuo, additional, Ito, Kimihito, additional, and Kida, Hiroshi, additional

Published
2024
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6. Mpox Neutralizing Antibody Response to LC16m8 Vaccine in Healthy Adults

Author

Morino, Eriko, primary, Mine, Sohtaro, additional, Tomita, Noriko, additional, Uemura, Yukari, additional, Shimizu, Yosuke, additional, Saito, Sho, additional, Suzuki, Tetsuya, additional, Okumura, Nobumasa, additional, Iwasaki, Haruka, additional, Terada, Junko, additional, Ainai, Akira, additional, Sakai, Yusuke, additional, Park, Eunsil, additional, Seki, Sayuri, additional, Akazawa, Daisuke, additional, Shimojima, Masayuki, additional, Shiwa-Sudo, Nozomi, additional, Virhuez-Mendoza, Milagros, additional, Miyauchi, Kosuke, additional, Moriyama, Saya, additional, Iwata-Yoshikawa, Naoko, additional, Harada, Michiko, additional, Harada, Shigeyoshi, additional, Hishiki, Takayuki, additional, Kotaki, Ryutaro, additional, Matsumura, Takayuki, additional, Miyamoto, Sho, additional, Kanno, Takayuki, additional, Isogawa, Masanori, additional, Watashi, Koichi, additional, Nagata, Noriyo, additional, Ebihara, Hideki, additional, Takahashi, Yoshimasa, additional, Maeda, Ken, additional, Matano, Tetsuro, additional, Wakita, Takaji, additional, Suzuki, Tadaki, additional, Sugiura, Wataru, additional, Ohmagari, Norio, additional, and Ujiie, Mugen, additional

Published
2024
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7. Author Correction: Immune response and protective efficacy of the SARS-CoV-2 recombinant spike protein vaccine S-268019-b in mice

Author

Homma, Tomoyuki, primary, Nagata, Noriyo, additional, Hashimoto, Masayuki, additional, Iwata-Yoshikawa, Naoko, additional, Seki, Naomi M., additional, Shiwa-Sudo, Nozomi, additional, Ainai, Akira, additional, Dohi, Keiji, additional, Nikaido, Eiji, additional, Mukai, Akiko, additional, Ukai, Yuuta, additional, Nakagawa, Takayuki, additional, Shimo, Yusuke, additional, Maeda, Hiroki, additional, Shirai, Seiki, additional, Aoki, Miwa, additional, Sonoyama, Takuhiro, additional, Sato, Mamoru, additional, Fumoto, Masataka, additional, Nagira, Morio, additional, Nakata, Fumihisa, additional, Hashiguchi, Takao, additional, Suzuki, Tadaki, additional, Omoto, Shinya, additional, and Hasegawa, Hideki, additional

Published
2024
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