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Accurate and effective load forecasting is very important for real-time operation and dispatching of power systems. In this paper, a prediction model that incorporates variable selection and sparse Transformer is proposed. Static and temporal variables are used as inputs to give full play to the information enhancement of static variables in the global time range. The variable weighting component is designed based on the gating mechanism with which different weights are assigned to the variables according to their relevance to the predicted output. A two-layer coding structure is designed for temporal feature extraction, attention is sparse, and future moment loads are predicted by multivariate inputs. The proposed model is validated using real power load data, and the experimental results show that it can improve the prediction accuracy and prediction efficiency of mid-long term load forecasting.(准确且有效的负荷预测对于电力系统的实时运行和调度非常重要。提出了一种融合变量选择与稀疏Transformer模型的预测方法，将静态变量和时序变量作为输入，充分发挥静态变量在全局时间范围内的信息增强作用，基于门控机制设计变量分权组件，根据变量与预测结果的相关性，赋予变量不同的权重。设计了双层编码结构，进行时序特征提取，对注意力进行稀疏处理，通过多变量输入对未来时刻负荷进行预测。基于真实电力负荷数据的实验表明，本文模型能够提高中长期负荷预测精度和效率。)

在非地面网络中，依托低轨通信卫星的星地链路、卫星载荷以及地面终端等资源，实现定位解算，是实现未来6G通感一体化的重要技术手段之一。在手机直连卫星等场景下，终端设计上往往只与一颗卫星进行通信，探索单星定位方法具有十分迫切的意义。针对以往单星连续观测定位精度因子差、时钟同步困难、收敛速度慢等难题，提出了一种低轨星座场景下的双向测量差分定位方法，并基于卫星位置精度因子设计了位置更新策略。利用星地链路，采用单程双向测距方法消除时钟误差，通过时间累计测量、终端随机切换的方式弥补单星观测的空间缺陷，优化了终端定位性能。在仿真场景下，基于SpaceX的卫星轨道参数，对所提方案进行了验证，结果表明，采用随机切换卫星的方法进行测量，相比于未切换保持单星测量的终端，定位性能提升近100%；联合解算多个时刻观测数据，能够提升精度收敛速度，减小定位误差，在180 s的仿真时间内利用512次观测数据，当终端切换次数为19次时，最优定位精度可达299.5 m。

Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

系统性红斑狼疮（SLE）是一种系统性自身免疫疾病, 临床异质性强, 以多器官不同程度受累、病情反复复 发与缓解、体内存在大量自身抗体为主要特点。寻找安全有效的治疗药物和治疗方法来延缓疾病进展, 降低其发病 率和病死率是当前临床关注的重点。羟氯喹是氯喹的羟基化类似物, 治疗 SLE 效果较为显著。HCQ 可通过抑制 Toll 样受体信号传导、阻断抗原呈递、抑制细胞自噬、抑制钙动员等多种途径发挥对 SLE 的治疗作用。HCQ 作为 SLE 的基础用药, 常与糖皮质激素、免疫抑制剂、生物制剂联合应用, 对改善临床症状、延缓疾病进展、改善 SLE 相关 并发症具有显著效果。探讨 HCQ 治疗 SLE 的作用机制及疗效, 能够为临床治疗 SLE 提供更充分的理论依据, 并扩 大 HCQ 的临床应用。 [ABSTRACT FROM AUTHOR]

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Copyright of Journal of Synthetic Crystals is the property of Journal of Synthetic Crystals Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of CT Theory & Applications is the property of Editorial Department of CT Theory & Applications and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

AIM: This study aims to investigate the expression differences of the ultraconserved RNA gene cluster uc. 102-uc. 106 and its host gene Obg-like ATPase 1(OLA1) in various tissues of C57BL/6J mice. METHODS: Five healthy male C57BL/6J mice aged 8~10 weeks were selected, and under normal physiological conditions, various tis⁃ sues and organs, including liver, testis, bone marrow, brain, kidney, blood, lung, colon, thymus, spleen, stomach, heart, lymph nodes and bladder, were collected. Simultaneously, magnetic bead separation technology was employed to extract bone marrow blood cells, including B cells, macrophages, erythroid precursor, and mature red blood cells. The expression levels of uc. 102-uc. 106 and OLA1 mRNA were determined by RT-qPCR with GAPDH as the internal reference. RESULTS: The OLA1 mRNA exhibited high expression levels in the brain, lymph nodes, testis and thymus of C57BL/6J mice, and low expression levels in the liver, spleen, lung, colon and peripheral blood (P<0. 05). The expression trend of the uc. 102-uc. 106 gene cluster was generally opposite to that of OLA1 mRNA, except for both exhibiting high expression levels in testicular tissue (P<0. 05). In blood cells, the OLA1 mRNA and the uc. 102-uc. 106 gene cluster showed the highest expression levels in B cells and the lowest expression levels in mature red blood cells (P<0. 05). CONCLUSION: This study indicates that OLA1 gene and uc. 102-uc. 106 gene cluster are expressed in different tissues and blood cells of C57BL/6J mice. Notably, the high expression levels of OLA1 gene and uc. 102-uc. 106 gene cluster in the mouse testis suggest a potential association with male reproductive functions [ABSTRACT FROM AUTHOR]

In this paper, the properties of T700 carbon fiber/epoxy resin matrix composites with pore damage were studied after aging in salt solution with different concentration, time and temperature, and the failure mechanism was analyzed. The mass change, SEM microstructure, glass transition temperature, infrared spectrum analysis and open hole tensile properties of the samples were analyzed after soaking in salt solution. The results show that the concentration of the salt solution has little effect on the properties of the material, while the aging time and temperature of the salt solution have more obvious effect on it. With the increase of temperature and time, the faster the moisture absorption rate, the greater the decrease of the glass transition temperature, the more serious the damage of the specimen morphology, the damage of the interface between the fiber and the matrix, and the open hole tensile strength. [ABSTRACT FROM AUTHOR]

Fusarium crown rot (FCR), mainly caused by Fusarium pseudograminearum, is a serious fungal disease that affects wheat yield. To determine the inhibitory activity of metconazole to F. pseudograminearum in Henan province, the toxicity of metconazole against three randomly selected isolates (JY2208, HB2201, and XC2116) at different developmental stages was determined from 219 isolates tested. The combined toxicity of metconazole with prochloraz, phenamacril, fluazinam, and fludioxonil against isolate JY2208 was determined according to the mass ratio of 5 : 1, 3 : 1, 1 : 1, 1 : 3, 1 : 5. The indoor control efficacy of metconazole against FCR was determined by the wheat coleoptile inoculation method. The results showed that the average EC50 values of mycelium growth, sporulation quantity, spore germination, and germ tube elongation of three isolates were (0.0397 ± 0.0035) μg/mL, (0.9549 ± 0.1152) μg/mL, (0.6114 ± 0.0393) μg/mL, and (0.0235 ± 0.0015) μg/mL, respectively. The EC50 values of metconazole, inhibiting mycelium growth of 219 isolates of F. pseudograminearum, ranged from 0.0207 to 0.0839 μg/mL, with an average value of (0.0406 ± 0.0114) μg/mL. The sensitivity frequency distribution was a continuous single-peak curve, which could serve as the baseline sensitivity of F. pseudograminearum to metconazole in Henan Province. The synergy ratios (SR) of metconazole combined with prochloraz, phenamacril, fluazinam, and fludioxonil ranged from 0.51 to 2.32. Different combinations and ratios of the mixture demonstrated either additive inhibition or synergistic inhibition efficacy. These results indicated that metconazole can be used in combination with prochloraz, phenamacril, fluazinam, and fludioxonil. Metconazole and fluazinam, with a mass ratio of 5 : 1, exhibited the strongest synergistic inhibition effect, achieving the maximum synergy ratio, with an SR of 2.32. Under laboratory conditions, the combination of 8% metconazole suspension and 50% fluazinam suspension, with the active ingredient of mass ratio of 5 : 1, achieved 100% control efficacy at the concentration of 80 μg/mL. These results could provide a basis for controlling the Fusarium crown rot caused by F. pseudograminearum. [ABSTRACT FROM AUTHOR]

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Copyright of Chinese Journal of Computational Mechanics / Jisuan Lixue Xuebao is the property of Chinese Journal of Computational Mechanics Editorial Office, Dalian University of Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Asian Journals of Ecotoxicology is the property of Gai Kan Bian Wei Hui and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

BACKGROUND: Tumor necrosis factor-α is a broadly acting inflammatory cytokine that plays an important role in the immune inflammatory response of the body. The current study concluded that tumor necrosis factor-α has significant biological effects on a variety of bone tissue cells. OBJECTIVE: To summarize the expression and action pathways of tumor necrosis factor-α in osteoblastic and osteoclastic cells to further elucidate the regulatory role of tumor necrosis factor-α on bone tissue cells. METHODS: PubMed and CNKI were searched until March 2023, and the Chinese search terms included “tumor necrosis factor α, osteoblast, osteoclast, osteoclast, osteoprogenitor”; the English search terms included “TNF-α, osteoblast, osteoclast, osteocyte, osteoprogenitor cell”. The corresponding criteria were established according to the research needs, and the final literature was screened. Finally, 77 articles were included for review. RESULTS AND CONCLUSION: (1) Tumor necrosis factor-α is participating in regulating the recruitment, appreciation, and differentiation of osteoprogenitor cells, but leads to osteoprogenitor cell stripping and death under specific environments. It also participates in bone resorption directly or indirectly through secreted enzymes. (2) Tumor necrosis factor-α can increase the level of inflammatory factors in the environment by activating relevant signaling pathways in osteoclast lineage cells or directly induce the generation of osteoclasts in specific environments. (3) Tumor necrosis factor-α can inhibit osteogenic differentiation by activating nuclear factor-κB signaling pathway, inhibiting the expression of transcription factors such as RUNX2 and Osterix, and inducing apoptosis and necrotizing apoptosis in osteoblasts. (4) Tumor necrosis factor-α inhibits osteogenesis and promotes osteoclastogenesis by activating the nuclear factor-κB signaling pathway in osteocytes and inducing cytokines such as RANKL, SOST, and DKK1, while enhancing apoptosis of the osteocytes, as well as bone resorption around the apoptotic bone tissue. (5) Taken together, the effect of tumor necrosis factor-α in bone tissue is mainly to inhibit osteogenesis and promote osteoclastosis. The biological effect of tumor necrosis factor-α in bone tissue cells is usually dependent on the activation of tumor necrosis factor receptor and nuclear factor-κB signaling pathways. (6) The interaction of tumor necrosis factor-α with other tissue cell types surrounding bone tissue and its role in bone immune regulation still deserve attention in future studies. [ABSTRACT FROM AUTHOR]

Copyright of Food Research & Development is the property of Food Research & Development Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The experiment aimed to comprehensively understand the nutritional characteristics of fish in the ponds of the Dahuangpu Wetland buffer zone. The conventional nutritional components, mineral content, as well as the amino acid and fatty acid composition in the muscles of the Hypophthalmichthys molitrix, Aristichthys nobilis, and Plagiognathops microlepis from the ponds in the Dahuangpu Wetland buffer zone were analyzed. The results showed that the muscle protein content of Hypophthalmichthys molitrix, Aristichthys nobilis, and Plagiognathops microlepis were 15.00%, 15.60%, and 13.80%, respectively, with crude fat content at 0.60%, 0.50%, and 1.10%. They were rich in macro elements such as potassium, sodium, calcium, magnesium, and phosphorus required by the human body, as well as trace elements like iron, zinc, and selenium. All three species had 16 kinds of amino acids detected in their muscles, with high glutamic acid content. The essential amino acids accounted for 38.69%, 38.76%, and 39.98% of the total amino acids, with essential amino acid indices of 101.90, 83.88, and 87.18 respectively. Hypophthalmichthys molitrix, Aristichthys nobilis, and Plagiognathops microlepis muscles were found to contain 10, 10, and 14 kinds of fatty acids respectively, with the order of saturated fatty acids, monounsaturated fatty acids, and polyunsaturated fatty acids from high to low being Plagiognathops microlepis, Hypophthalmichthys molitrix, and Aristichthys nobilis. The study indicates that Hypophthalmichthys molitrix, Aristichthys nobilis, and Plagiognathops microlepis from the Dahuangpu buffer zone ponds are good sources of protein with a reasonable composition of amino acids, rich in minerals and beneficial fatty acids, and have high nutritional value and edibility. [ABSTRACT FROM AUTHOR]

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