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新型储能技术的快速进步为提升电力系统灵活性提供了更多技术选择，也为构建竞争性灵活资源市场提供了条件。国外部分独立系统运营商为适应储能物理特性，在能量市场、辅助服务市场、容量市场、输电资产方面做了机制探索；国内一系列电力体制改革文件强调探索容量补偿机制以鼓励新型储能投资建设，但国家层面尚未出台针对新型储能的容量补偿政策。结合主流新型储能技术经济参数与国内典型地区现货市场价格曲线，测算了现货市场环境下各类新型储能经济性差异与未来趋势，并基于国内外容量补偿机制经验与研究成果，研究不同容量补偿机制情景下容量电价对提升新型储能经济性的作用。研究发现，以锂电池为代表的新型储能已开始显现相对于抽水蓄能的经济性，赋予新型储能独立市场地位，鼓励其参与电力现货市场，有助于降低新能源发电系统消纳成本。然而，目前新型储能参与电力现货市场仍面临阻碍，为此在容量补偿、现货与辅助服务市场建设等方面给出了政策建议。

本文提出了一种新型的免拆模钢筋桁架楼承板（PFCB-钢筋桁架楼承板），是由钢筋桁架和纤维水泥板底模板（permanent fiber cement bottom form）用自攻螺钉和连接件预制连接而成整体的装配式楼承板。为研究PFCB-钢筋桁架楼承板施工阶段的受力性能，并考虑施工时混凝土砂浆中水分或降水天气对纤维水泥板底模的影响，对PFCB-钢筋桁架楼承板进行了饱水状态下承压能力试验。采用有限元软件模拟对楼承板结构进行了参数化分析，得到了楼承板极限承载力与刚度变化规律，发现PFCB-钢筋桁架楼承板在均布设计组合荷载以及集中荷载下性能良好，3 600 mm跨度的试件在极限荷载下挠度控制在6 mm至8 mm；改变自攻螺钉间距与钢筋桁架高度对试件的承载力影响比较明显。

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肾移植是目前终末期肾脏病最有效的治疗方案, 但排斥反应是肾移植术后面临的最大挑战, 也是导致移 植肾失功的重要原因。目前, 临床评估移植肾功能常规的免疫监测手段主要依赖于血肌酐检测和移植肾穿刺活 检。但血肌酐检测不能及时准确地反映免疫排斥状态, 而移植肾穿刺活检则具有创伤性, 不适合长期应用。因此, 临床亟需寻找一些操作简单且足够准确的免疫监测标志物, 以便准确地识别肾移植术后排斥反应并指导临床治 疗。细胞因子是一类能在细胞间传递信息, 具有免疫调节和效应功能的低相对分子质量蛋白质或小分子多肽, 是由 活化的免疫细胞及某些基质细胞表达并分泌的活性物质, 其主要生物学功能是介导和调节免疫应答及炎症反应。其中, 与肾移植免疫排斥反应发生密切相关的细胞因子有 IL-10/TNF-α、IL-33、IL-34、IL-6 等。在这些细胞因子中, 有些能够增强免疫应答, 促进排斥反应发生; 有些则能够抑制免疫细胞活化和增殖, 维持免疫耐受。因此, 这些细胞 因子有望成为肾移植术后免疫监测的潜在生物标志物。 [ABSTRACT FROM AUTHOR]

Objective To understand the current status of knowledge, attitude/belief, and practice (KAP) regarding pulmonary rehabilitation among patients with pneumoconiosis, analyze the influencing factors, and provide a reference for further intervention measures. Methods From January 2021 to December 2022, 168 inpatients with pneumoconiosis in a certain hospital were studied. The Questionnaire Star applet was used to conduct a survey using a general information questionnaire and a self -designed pulmonary rehabilitation KAP questionnaire. Multiple linear regression analysis was performed to analyze the influencing factors of KAP in pulmonary rehabilitation. Results The total KAP score of the study subjects was (88.77 ± 14.63), with a score rate of 68.28%. The scores for each dimension of KAP were (41.62 ± 5.93), (16.89 ± 1.80), and (30.26 ± 9.50), respectively, with a score rate of 69.37%, 84.45%, and 60.52%, respectively, which all were at a moderate level. Knowledge with attitude, knowledge with behavior, and behavior with attitude were moderately positively correlated (r = 0.439, r = 0.507, r = 0.549, all P < 0.05). Multiple linear regression analysis showed that age, per capita monthly family income, and comorbidities or complications were possible influencing factors for the knowledge score of pulmonary rehabilitation. Among them, compared with the 50 to 59 year age group, the knowledge score of patients under the 50 year age group increased by 2.619 points (P < 0.01); compared with the group with a per capita monthly family income of less than 2 000 yuan, the knowledge scores of the groups with an income of 2 000 to 4 000 yuan and above 4 000 yuan increased by 1.991 points and 3.831 points, respectively (both P < 0.05); compared with the group with comorbidities or complications, the knowledge score of the group without comorbidities or complications increased by 1.976 points (P < 0.05). The age, diagnostic stage of pneumoconiosis, and the number of hospitalizations for pneumoconiosis were possible influencing factors for the belief score of pulmonary rehabilitation. In particular, compared with the 50 to 59 year age group, the belief score of patients aged 60 and above decreased by 1.963 points (P < 0.01); compared with patients with stage Ⅱ pneumoconiosis, the belief score of patients with stage I pneumoconiosis increased by 0.950 points (P < 0.01); compared with patients hospitalized 2 to 3 times for pneumoconiosis, the belief score of patients hospitalized for the first time increased by 1.609 points (P < 0.01). Diagnostic stage, educational level, and comorbidities or complications were possible influencing factors for the behavior score of pulmonary rehabilitation. Compared with patients with stage Ⅱ pneumoconiosis, the behavior score of patients with stage I pneumoconiosis increased by 6.570 points (P < 0.01); compared with the junior high school education group, the behavior scores of the primary school and high school or above groups increased by 5.911 and 5.996 points, respectively (both P < 0.01); compared with the group with comorbidities or complications, the behavior score of the group without comorbidities or complications decreased by 6.100 points (P < 0.05). Conclusions The levels of knowledge, belief, and behavior regarding pulmonary rehabilitation among patients with pneumoconiosis need to be improved. Clinically, corresponding nursing interventions should be formulated based on the current status and influencing factors of KAP in pulmonary rehabilitation among patients with pneumoconiosis to improve their KAP levels and quality of life. [ABSTRACT FROM AUTHOR]

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BACKGROUND: The alteration of miR-146a-3p level is a common event in the pathogenesis of most neurological diseases, and the specific mechanism of miR146a-3p regulation of astrocytes has not been studied. OBJECTIVE: To verify that miR-146a-3p regulates astrocyte proliferation, migration and apoptosis through insulin-like growth factor 1. METHODS: 12 SD rats were divided into a sham operation group and a spinal cord injury group, with six rats in each group. RNA sequencing analysis was performed on the spinal cord tissues of all groups 2 weeks after surgery to screen out the differential genes (log2FC > 2), and to select spinal cord injury-related genes (Score > 20) in the Genecards database, and then to predict the target genes of miR-146a-3p by Targetscan. The intersection of three gene sets was obtained to screen out insulin-like growth factor 1 as one of the important target genes. qPCR, western blot assay and immunohistochemistry were performed to analyze the expression level of insulin-like growth factor 1 in spinal cord tissues. The primary astrocytes were divided into NC group, NC-mimics group and miR-146a-3p mimics group. Annexin-V/PI staining was used to detect cell apoptosis. CCK-8 assay was used to detect cell proliferation. Transwell assay was used to detect cell migration ability. RESULTS AND CONCLUSION: The expression of miR-146a-3p in the spinal cord tissue of the spinal cord injury group was lower than that of the sham operation group (P < 0.05). The expression of insulin-like growth factor 1 in the spinal cord tissue of the spinal cord injury group was higher than that of the sham operation group (P < 0.05). Compared with the NC group and NC-mimics group, the apoptotic rate of astrocytes was increased (P < 0.01); the proliferation of astrocytes was decreased (P < 0.01) and the number of migration was decreased (P < 0.01) in the miR-146a-3p mimics group. To conclude, the expression of miR-146a-3p decreased and the expression of insulin-like growth factor 1 increased in spinal cord tissue after spinal cord injury. miR -146a-3p targeted regulation of insulin-like growth factor 1 in astrocytes, inhibited the proliferation and migration of astrocytes and promoted their apoptosis. [ABSTRACT FROM AUTHOR]

During the Tang and Song dynasties, Zen Buddhism was composed of the “Five Schools and Seven Sects”. The tea Zen culture in Jiangxi was represented by the Huairang school of Zen Buddhism in Nanyue. Since the opening of the Zen tea ceremony at Baizhang Huaihai, the founder of Huangbo tea had been renowned for Huangbo Zen tea. It was not until the Song Dynasty that Yuanwu Keqin pioneered the tea ceremony culture in Japan. Yangqi Fanghui was the founder of the Yangqi School of the Linji Sect in the Song Dynasty. His tea Zen inherited the fortunes of Baizhang Huaihai and Huangbo Xiyun, and integrated the teachings of Tiantong Xianqi. His teachings had been passed down to Yuanwu Keqin for three generations, and eventually spread to Japan, making great contributions to the dissemination and development of Chinese Zen tea culture. This also reflects one aspect of the development of ancient Chinese tea Zen culture. Yangqi Fanghui combined tea culture with Zen culture, using tea as an opportunity to practice Zen and exploring the harmony of tea drinking. This not only reflects the Zen philosophy of “compassion for the benefit of others and the elevation of the school of thought”, but also reflects the transformation of Zen style brought about by the integration of tea into Zen and the tasting of Zen in tea since the Song Dynasty. [ABSTRACT FROM AUTHOR]

Objective: To detect the expression of Toll-like receptor 7 (TLR7) in blood neutrophils of patients with allergic rhinitis (AR), allergic asthma (AA) and allergic rhinitis combined with allergic asthma (ARA) before and after allergen challenge. Methods: A total of 44 AR, 36 AA, 19 ARA patients and 19 healthy control (HC) were recruited, the extracts of Artemisia siever⁃ siana wild allergen (ASWE), house dust mite allergen (HDME) and Platanus pollen allergen (PPAE) were used to challenge peripheral blood of HC as well as the patients, the expression of TLR7 in neutrophils was detected by flow cytometry. Results: In a resting state, compared with HC, upregulated expression of TLR7 in neutrophils in patients with airway allergy: the percentage of TLR7+ neutrophils in AR, AA, ARA patients increased 6 times, 3.18 times and 6.15 times, respectively, and the mean fluorescence intensity (MFI) of TLR7 expression in neutrophil in ARA was enhanced by 24%. The results of allergen challenge tests showed that the expression of neutrophils TLR7 did not change in HC subjects after the allergen challenge, whereas the expression of TLR7 in neutrophils of patients with airway allergy was upregulated after the allergens challenge. After HDME and PPAE challenge, the percentage of TLR7+neutrophils in peripheral of AR patients increased by 8.40% and 33.03%, respectively, and the MFI of TLR7 enhanced by 29.62% and 35.72%, respectively. After ASWE and PPAE challenge. The percentage of TLR7+ neutrophils in peripheral of AA patients increased by 59.18% and 1.06 times, respectively, and the MFI of TLR7 enhanced by 68.93% and 47.33%, respectively. However, after HDME stimulation only enhanced the MFI of neutrophil TLR7 in AA patients by 66.14%; after HDME challenge, the percentage of TLR7 and MFI in peripheral blood neutrophils of patients with ARA increased by 21.05% and 35.61%, respectively, while after PPAE challenge, the percentage of TLR7+ cells in patients with ARA increased by 20.07%. Conclusion: The expression of TLR7 n blood neutrophils is increased in patients with allergic airway diseases after allergen stimulation, suggesting that allergens may be involved in the occurrence and development of allergic airway diseases by inducing TLR7 expression changes in neutrophils. [ABSTRACT FROM AUTHOR]

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Environmental soil science is a compulsory basic course of environmental science and engineering majors. The course is rich in ideological and political elements, which provides favorable conditions for carrying out the ideological and political education. This paper deeply excavated the connotation of moral education and education elements contained in each chapter of the course, and organically integrated ideology and politics education elements into class teaching. In the meantime, according to the professional talent training program and graduation requirements, and carried out political ideology and morality education combining curriculum content for students, and played the role of professional courses in educating function, so as to realize the fundamental task of moral education in colleges and universities. [ABSTRACT FROM AUTHOR]