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Previous studies suggested effectiveness of psilocybin in the field of mental health. FDA designated psilocybin as a "breakthrough therapy" for the treatment of treatment-resistant depression (TRD) in 2018. This paper provided a review of psilocybin's potential role in treatment of depression by focusing on published clinical trials. Studies showed that psilocybin, an agonist on 5-HT 2A receptors, manifests antidepressant and anxiolytic effects by increasing glutamate transmission, reducing brain inflammation, decreasing default mode network activity. In terms of clinical trials, eleven studies (six open-label and five double blinded randomized clinical trials [DB-RCTs]) trials exploring psilocybin's impact on depression were found. Among open-label studies, a pilot study on TRD patients demonstrated significant reductions in depressive symptoms after two psilocybin sessions. Psilocybin also improved cognitive bias associated with depression. Extension studies confirmed sustained improvements and high remission rates. Among five DB-RCTs, two showed that psilocybin led to significant reductions in anxiety and depression in cancer patients, and the improvements sustained for over six months. In MDD, psilocybin showed rapid reductions in depression, with higher remission rates compared to escitalopram in a DB-RCT. Another DB-RCT showed that psilocybin induced higher decrease in depression around 6 hours after their administrations than placebo. The last DB-RCT showed that in patients with TRD, a single dose of psilocybin 25 mg, but not psilocybin 10 mg, resulted in superior antidepressant effect than psilocybin 1 mg. Overall, psilocybin showed promise in treating depression and anxiety, with notable safety profiles. Further research should explore optimal dosages and long-term effects.

Optimizing soil water and fertilizer management can benefit crop production and soil environment. Alginate oligosaccharides (AOS) are natural biostimulants with fertilizer efficiency- and growth-promoting functions. However, there are few application strategies of AOS in citrus production, especially in combination with water and fertilizer regulations. In this paper, a two-year field trial was conducted to investigate the effects of AOS (AOS 0 , AOS 2.5 , AOS 5.0) strategies under different moisture conditions (W 80 , W 70 , W 60) on citrus yield, quality, water and fertilizer use efficiency, plant growth and soil environment. The results showed that drip irrigation with 2.5 g L−1AOS 8–10 times under W 70 (W 70 AOS 2.5) increased fruit yield, the total soluble sugar and sucrose content by 11.93%–13.31%, 15.16–17.47% and 18.92–20.81%, and fruit potassium and water use efficiency increased by 51.09%–62.21% and 12.01%–13.34%, respectively, and the effect of increase was better than the application in W 80 and W 60. Citrus growth showed that net photosynthetic rate of W 70 AOS 2.5 were significantly increased after 4th AOS application, and that total root length, surface area, and volume also increased at harvest. Soil analysis showed that drip-irrigated AOS reduced the loss rate of soil water under both W 60 and W 70 , increased proportions of water stable aggregates >0.25 mm in the soil. The available potassium content increased significantly in the 0–20 cm soil layer but decreased significantly in the 20–40 cm soil layer, and soil cation exchange capacity also increased significantly in the 0–20 cm layer, suggesting that AOS may slow water and potassium loss under low moisture conditions. In addition, AOS also increased the organic carbon content and the abundance of Pseudolabrys which dominant bacteria associated with carbon and nitrogen. The W 70 AOS 2.5 strategy exceeded other strategies in terms of overall evaluation score and net benefits, reducing irrigation water discharge to the environment by 620–700 m3 ha−1. Our study demonstrated the good potential of AOS in improving fruit production and soil properties. • Soil moisture coupled with alginate oligosaccharide strategy significantly improved yield and quality of citrus fruits. • Soil moisture coupled with alginate oligosaccharide strategy significantly improved potassium and water use efficiency. • Soil moisture coupled with alginate oligosaccharide strategy improved photosynthesis and root growth in citrus. • Soil moisture coupled with alginate oligosaccharide strategy improved soil fertility and rhizosphere environment. [ABSTRACT FROM AUTHOR]

The dominating set problem (DSP) is one of the most famous problems in combinatorial optimization. It is defined as follows. For a given graph G = (V , E) , a dominating set of G is a subset S ⊆ V such that every vertex in V ∖ S is adjacent to at least one vertex in S. Furthermore, the DSP is the problem of finding a minimum-size dominating set and the corresponding minimum size, the domination number of G. In this, work we investigate a variant of the DSP, the super dominating set problem (SDSP), which has attracted much attention during the last years. A dominating set S is called a super dominating set of G , if for every vertex u ∈ S ¯ = V ∖ S , there exists a v ∈ S such that N (v) ∩ S ¯ = N (v) ∖ S = { u }. Analogously, the SDSP is to find a minimum-size super dominating set, and the corresponding minimum size, the super domination number of G. The decision variants of both the DSP and the SDSP have been shown to be NP -hard. In this paper, we present tight bounds for the super domination number of the neighbourhood corona product, r -clique sum, and the Hajós sum of two graphs. Additionally, we present infinite families of graphs attaining our bounds. Finally, we give the exact number of minimum size super dominating sets for some graph classes. In particular, the number of super dominating sets for cycles has quite surprising properties as it varies between values of the set { 4 , n , 2 n , 5 n 2 − 10 n 8 } based on n mod 4. [ABSTRACT FROM AUTHOR]

Given a non-decreasing sequence S = (s 1 , s 2 , ... , s k) of positive integers, an S -packing coloring of a graph G is a partition of the vertex set of G into k subsets { V 1 , V 2 , ... , V k } such that for each 1 ≤ i ≤ k , the distance between any two distinct vertices u and v in V i is at least s i + 1. In this paper, we study the problem of S -packing coloring of cubic Halin graphs, and we prove that every cubic Halin graph is (1 , 1 , 2 , 3) -packing colorable. In addition, we prove that such graphs are (1 , 2 , 2 , 2 , 2 , 2) -packing colorable. [ABSTRACT FROM AUTHOR]

A matching in a graph is a set of pairwise nonadjacent edges. A maximum matching is a matching which covers as many vertices as possible. In this paper, using the Gallai–Edmonds Structure Theorem, we obtain a characterization of graphs each of whose edges belongs to at most one maximum matching. [ABSTRACT FROM AUTHOR]

This paper studies three edge-removing games on graphs. In each game, there are two players and a simple graph G at the beginning. The players take turns removing at least one edge of a certain type from the current graph. The one who cannot move loses the game, and the other one, who plays the last move, wins. This paper gives results for these games on some interesting classes of graphs by either computing their Grundy numbers or proposing winning strategies. [ABSTRACT FROM AUTHOR]

In computational and theoretical chemistry, the eccentricity matrix of graph has widely applications due to its effect of eccentricity in molecular graph. Since a molecular structure is modeled by hypergraph which has a higher accuracy than by graph, it is also interesting to study eccentricity matrix of hypergraph. The eccentricity spectral radius of H is the spectral radius of its eccentricity matrix. In this paper, some properties on eccentricity spectral radius of hypergraphs are obtained and some extremal structure of hypertrees are characterized. [ABSTRACT FROM AUTHOR]

Boolean functions used in symmetric-key encryption should have high higher-order nonlinearity to resist several known cryptographic attacks, such as algebraic attacks and low-degree approximation attacks. The higher-order nonlinearity also plays an important role in coding theory and theoretical computer science, since it relates to the covering radius of Reed–Muller codes and the Gowers norm, respectively. It is well-known that bent functions have the highest nonlinearity in an even number of variables and thus they possess the best ability to withstand fast correlation attacks and best affine approximation attacks. However, there is currently limited knowledge regarding the higher-order nonlinearity of bent functions because computing the higher-order nonlinearity, or even providing tight lower bounds, is an extremely hard task. In 1974, Dillon proposed two well-known classes of bent functions based on partial spread (in brief, PS), called PS − and PS + , respectively. He also exhibited a subclass of bent functions in PS − , known as partial spread affine plane(PS a p for short). In this paper, we provide a lower bound on the third-order nonlinearity of the simplest PS a p bent functions in n variables, where n ≥ 6 is even, by calculating the nonlinearities of all second-order derivatives of this kind of bent functions. Compared to the two known lower bounds on the third-order nonlinearity given by Carlet and Tang et al. respectively, our lower bound is much better than these two ones. [ABSTRACT FROM AUTHOR]

A dominating broadcast of a graph G is a function f : V (G) → { 0 , 1 , 2 , ... , diam (G) } such that f (v) ⩽ e (v) for all v ∈ V (G) , where e (v) is the eccentricity of v , and for every u ∈ V (G) , there exists a vertex v with f (v) ⩾ 1 and d (u , v) ⩽ f (v). The cost of f is ∑ v ∈ V (G) f (v). The minimum cost over all the dominating broadcasts of G is called the broadcast domination number γ b (G) of G. In this paper, we give new upper and lower bounds for γ b (G). We show that both the bounds are tight. Also, we improve the upper bound for a subclass of regular graphs. Further, we explore the broadcast domination numbers of generalized Petersen graphs and a subclass of circulant graphs. [ABSTRACT FROM AUTHOR]

A set of n drones with limited communication range is deployed to monitor a terrain partitioned into n pairwise disjoint and closed convex trajectories, one per drone. There is exactly one communication link between two trajectories if they are close enough, and drones can communicate provided they visit the link at the same time. If each robot flies around an assigned area and shares information with the neighbors periodically the system is said to be synchronized. Over time, one or more drones may fail and the ability to survey, communicate, and stay connected decreases, thus the robustness against drone failure becomes crucial. In this paper we study various problems related to the proper functioning of a synchronized system under drone failure. First, we provide efficient algorithms, both centralized and decentralized, for determining the connected components induced by the set of surviving drones. Second, we study coverage, isolation, and connectivity under a probabilistic failure model and show that, in the case of grids, the system is quite robust in the sense that it can tolerate a large probability of failure before drones fail to completely cover the terrain, become isolated, or the system loses full connectivity. [ABSTRACT FROM AUTHOR]

The topological structure of a recursive interconnection network can be modeled by an n -dimensional graph G n. A faulty vertex set (resp. edge set) of G n is called a t -embedded vertex (resp. edge) cut if the remaining network is disconnected and each vertex in the residual network is in a copy of fault-free t -dimensional graph G t. The t -embedded vertex connectivity ζ t (G n) (resp. the t -embedded edge connectivity η t (G n)) is defined as the minimum cardinality over all t -embedded vertex (resp. edge) cuts of G n. The m -ary n -dimensional hypercube G (n , m) has an elegant recursive structure and is also a generalized variant of the classical hypercube. This paper studies the reliability of the G (n , m) and generalizes some known results in ternary n -cubes. Specifically, we prove that ζ t (G (n , m)) = (m − 1) (n − t) m t for t ≤ n − 2 and η t (G (n , m)) = (m − 1) (n − t) m t for t ≤ n − 1. [ABSTRACT FROM AUTHOR]

In this paper, we study the distribution of parallelograms and rhombi in a given set in the plane over arbitrary finite fields F q 2. As an application, we improve the recent result due to Fitzpatrick, Iosevich, McDonald, and Wyman on the Vapnik–Chervonenkis dimension of the induced distance graph. [ABSTRACT FROM AUTHOR]

The use of nanoparticles has significantly increased in many areas, such as biomedical research, being highly useful as nanoprobes for imaging and as nanocarriers for drug delivery applications. Nevertheless, this potential can only be achieved with the correct characterization of the nanoparticles, since their size and shape can directly affect their biological behavior. In this study, we propose a novel approach for a monolayer deposition of gold and platinum nanoparticles on Si substrates suitable for medium energy ion scattering (MEIS) analysis. The samples were prepared using poly(ethylene glycol) 6000 (PEG 6000) as a coating agent for the substrates, utilizing a spin coater-a versatile, cost-effective, and practical technique. The samples were first analyzed with the RBS technique to assess the adhesion and the overlapping of the nanoparticles in the substrates coated with PEG 6000 and then characterized through the MEIS technique. The analysis through MEIS allowed the determination of the shape, size, and coverage area of the nanoparticles. Scanning and transmission electron microscopy were also performed on the samples, with the results corroborating the findings of the MEIS experiment. Together, the data obtained with microscopy and the MEIS technique suggests the effectiveness of the method in the production of monolayer samples. [ABSTRACT FROM AUTHOR]

A current-limiting and consequent direct current (DC) arc interruption requires an increase in arc resistance r a r c for a DC fuse. Flattery silica (SiO2) sand has been used as an arc quenching medium in fuses for decades. However, there are few reports about a novel arc quenching medium which enables more r a r c increases compared to flattery SiO2 sand. This paper uniquely selected a novel arc quenching medium based on the following material properties: (1) electrical resistivity and thermal conductivity in the solid phase, (2) the possibility of r a r c increasing in the gas phase, (3) the possibility of electrical insulation after re-solidification, and (4) the cost of materials. As a result, we originally selected a powder mixture of silicon-nitride (Si3N4) and flattery SiO2 sand as a promising novel arc quenching medium. Therefore, DC interruption experiments were performed using a Si3N4/flattery SiO2 sand powder mixture under different Si3N4 concentration conditions. As a result of 1000 A DC arc quenching experiments, the utilization of Si3N4 powder with the flattery SiO2 sand successfully increased the arc resistance r a r c during the arc quenching process. The increasing Si3N4 concentration exhibited a further increase in r a r c during the arc quenching process. As a result of the r a r c increase, the arc quenching time was significantly shortened to 30 ms for 30 wt.% Si3N4 conditions from 54 ms for the SiO2 sand conditions. In addition, utilization of Si3N4 powder achieved high insulation resistance over few MΩ after DC arc interruption. The above results clearly indicate that utilization of Si3N4 powder with flattery SiO2 sand can increase the DC interruption performance of the fuse. [ABSTRACT FROM AUTHOR]

In this paper, the characteristics of a nanosecond spark discharge with a pin–pin electrode configuration have been systematically studied. Both a streak camera with high temporal resolution and an intensified charge-coupled device (ICCD) camera are employed together to investigate the breakdown and evolution process of the discharge. The formation of initial breakdown and mode transition from streamer to spark in the electrode gap are clearly observed on the time scale of several nanoseconds with a temporal resolution of 100 ps. In addition, the time-resolved spectra technology is also used to analyze the generation and quenching mechanisms of reactive species, the electron density, and the electron temperature. The results show that there is a 1.25 ns initial discharge breakdown and that a bright cathode spot exists before the transformation from streamer to spark channel. After a faster cathode filament and a slower anode filament propagate and merge at the electrode gap, the spark discharge phase begins. The generation processes of different reactive species depend on the discharge phase to a great extent. The N2* is first generated during the streamer phase while the O*, N*, and N+ are mainly generated under the spark phase, in which the electron temperature calculated by Boltzmann plots is 2.74 eV, and the electron density determined from the Stark broadening of O lines is on the order of 1016 cm−3. [ABSTRACT FROM AUTHOR]

An electromagnetic parameter-retrieval-based surrogate-assisted optimization (PSAO) algorithm is presented to reduce radar cross section (RCS) by optimizing the on-platform honeycomb absorbing structures. To facilitate the optimization process, the honeycomb structure is transformed to an anisotropic homogeneous slab, and the effective parameters of the slab are extracted by the retrieval algorithm. A multi-fidelity model is employed to reduce the computing-time consumption, in which a Gaussian process (GP) regression model is used as the substitute for the coarse model. The GP model establishes a relationship between the geometry of the honeycomb structure and the RCS response of the target coated with the equivalent slab. Finally, the optimization result of the fine model is achieved through a space mapping strategy. The accuracy of the parameter extraction algorithm is verified by analyzing the honeycomb absorbing structure. Subsequently, the proposed optimization method is applied to a metal plate and a metal cylinder, resulting in a 10 dB reduction of RCS in broadband and wide-angle scenarios. This demonstrates the applicability of the proposed PSAO algorithm to both planar and conformal on-platform honeycomb absorbing structures. Furthermore, an NACA0015 foil is analyzed, showing an average RCS reduction of 10 dB and a minimum RCS reduction of 5 dB in the X-band. These results indicate that the PSAO approach can effectively apply to complicated targets. Additionally, the proposed method exhibits significant advantages in terms of computational accuracy and efficiency compared to the traditional genetic algorithm. [ABSTRACT FROM AUTHOR]

• A WGM-FP hybrid microcavity for dual-parameter measurement is presented. • The two signal components could be well demodulated. • The crosstalk between concentration and temperature of NaCl solutions is reduced. Whispering gallery mode (WGM) resonator is sensitive to the external medium change due to its strong light-matter interaction. However, the temperature sensitivity of silica-based WGM resonators would cause crosstalk, which is a fatal shortcoming for those high-quality (Q) resonators. In this paper, a hybrid microcavity including WGM resonance and Fabry–Pérot (FP) interference is proposed for simultaneous measurement of NaCl concentration and temperature, using the same microcavity in the same system to obtain two types of optical signals. The experimental results indicate that the maximum measurement error of NaCl concentration and temperature without compensation is about ± 0.026 % and ± 1.1 °C, while they would be ± 0.012 % and ± 0.3 °C after compensation. Sharing one microcavity enables temperature compensation to achieve temperature synchronization, and sharing of one system ensures the simplicity and stability of the sensing platform. [ABSTRACT FROM AUTHOR]

Precisely controlled digital pulse plays a crucial role in various cutting-edge testing applications. This paper introduces an innovative approach to digital pulse generation utilizing an FPGA transceiver, with the AMD evaluation board ZCU102 serving as a demonstrative platform. In the normal mode, the transmitter generates a serial bit stream, enabling the generation of single or repeated pulses with configurable width and period. In the high precision mode, an internal dedicated phase interpolator enhances the configuration step size for width and period by up to 64 times, providing finer phase shift capability. The demonstration system operates at a line rate of 10 Gbps, achieving a resolution of 100 ps in normal mode and 1.5625 ps in high precision mode. This paper details the design methodology, presents test results for pulse width uncertainty and non-linearity, and showcases achieved period jitter and time interval error jitter as small as around 1 ps. • A novel digital pulse generator is implemented with GTH transceiver in AMD FPGA. • Transceiver can produce digital pulse by controlling the sent bits with low jitter. • Resolution can be further enhanced by phase interpolator in the transceiver. [ABSTRACT FROM AUTHOR]

• Nonuniform E-field is restored by measuring E-FISH signals along probing laser. • Convergence of inversion algorism related to measuring system parameter is given. • Accuracy of inversion algorism is validated via experimental investigations. • Robustness of inversion algorism in resisting measurement noise is confirmed. The electric field-induced second-harmonic generation (E-FISH) method can offer high spatiotemporal resolution in electric field measurement, but faces challenge in reconstructing the inhomogeneous electric field along the probing laser. This paper presents an inversion method to reconstruct the electric field profile by using E-FISH signals measured from multiple points along the probing laser. The relationship between the condition number of the inversion coefficient matrix and the parameters of E-FISH measurement system is clarified. The inversion method is validated through experimental investigations conducted in three different electrode configurations, namely the plate-to-plate gap, the rod-to-rod gap, and the rod-plate gap. With the inhomogeneity coefficient varies from 1 to 10.7, the maximum deviation between the measured electric field and the finite element simulation is less than 6%. This method does not rely on priori assumptions and electrode configurations, and exhibits good robustness in resisting the effect of measurement noise on the inversion accuracy. [ABSTRACT FROM AUTHOR]

NP3L (Non perspective-three-line) aims to estimate the poses of three cameras from three line correspondences, which can be applied into multi-camera systems for localization. Existing methods lack a deep insight for different line distributions, resulting in the inaccurate pose estimation. This paper focuses on the robust and accurate solution for different line distributions. First, for the general situation, an algebraic method is proposed to establish two intermediate coordinates to simplify the rotation matrix. Subsequently, a polynomial is constructed for rotation and translation estimation. Second, this paper divides line distributions into six categories. Based on the proposed method, a specific simplified edition is designed for each distribution. Third, this paper provides insightful analyses of the solution number, polynomial order, existences of closed-form solutions for all line distributions. In experiments, the comparative results verify that the proposed methods can estimate relatively accurate camera pose, and outperform state-of-the-art methods on the synthetic and real-world datasets. • Algebraic methods are proposed for NP3L problem in general and special distributions. • This paper analyzes the properties of the proposed methods for special distributions. • The proposed methods offer accuracy and precision compared to the state-of-the-arts. [ABSTRACT FROM AUTHOR]