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Accurate and efficient predictions of three-dimensional subsurface stress changes are required for the assessment of geothermal operations with respect to fault stability and the potential risk for induced seismicity. This work extends the model capabilities of Mechanical Analysis of Complex Reservoirs for Induced Seismicity (MACRIS) to account for high-resolution thermo-elastic stress evaluations in structurally complex (i.e. faulted) and matrix permeability dominated geothermal systems. By adopting a mesh-free approach suitable to industry standard flow simulation models, MACRIS is capable of preserving the complex 3D hydraulic development of the injected cold-water volume and the 3D geometrical complexities of the reservoir model. The workflow has been applied to three-dimensional models with clastic reservoir characteristics representative for low enthalpy geothermal exploitation in the Netherlands. The models are marked by a single fault, subject to no and normal offset. Comparison of simulated stress evolutions in MACRIS with alternative analytical solutions highlight the effects of stress arching involved in the poro- and thermo-elastic stress developments on complex faults intersected by or in direct contact with the cold-water volume. Results are in agreement with previous studies and show the effect of thermal stressing to be dominant, arching of stresses to occur at the rim of the cold-water volume, and in cooling reservoirs, the intersection area of the cold-water volume in direct contact with the fault plane to be the main driver for fault reactivation and subsequent seismic potential. Moreover, results show the effects of stress arching (i) to be enhanced in the case of reservoir throw and flow compartmentalization, and (ii) to be reduced by a relative increase in conductive heat transfer between the reservoir and surrounding formations. [ABSTRACT FROM AUTHOR]

Background: The objective of this study was to examine the prevalence of unhealthy lifestyle behaviors, overweight, and obesity in Dutch childhood cancer survivors (CCSs) compared with sibling controls and the Dutch general population. Other aims were to assess associated factors of unhealthy lifestyle behaviors, overweight, and obesity and to identify subgroups of CCSs at risk for these unhealthy statuses., Methods: The authors included 2253 CCSs and 906 siblings from the Dutch Childhood Cancer Survivor Study-Late Effects After Childhood Cancer cohort, part 1, and added data from the Dutch general population. Questionnaire data were collected on overweight and obesity (body mass index >25.0 kg/m 2 ), meeting physical activity guidelines (>150 minutes per week of moderate or vigorous exercises), excessive alcohol consumption (>14 and >21 alcoholic consumptions per week for women and men, respectively), daily smoking, and monthly drug use. Multivariable logistic regression analyses and two-step cluster analyses were performed to examine sociodemographic-related, health-related, cancer-related, and treatment-related associated factors of unhealthy lifestyle behaviors and to identify subgroups of CCSs at risk for multiple unhealthy behaviors., Results: CCSs more often did not meet physical activity guidelines than their siblings (30.0% vs. 19.3%; p < .001). Married as marital status, lower education level, nonstudent status, and comorbidities were common associated factors for a body mass index ≥25.0 kg/m 2 and insufficient physical activity, whereas male sex and lower education were shared associated factors for excessive alcohol consumption, daily smoking, and monthly drug use. A subgroup of CCSs was identified as excessive alcohol consumers, daily smokers, and monthly drug users., Conclusions: The current results emphasize the factors associated with unhealthy behaviors and the potential identification of CCSs who exhibit multiple unhealthy lifestyle behaviors., (© 2024 The Authors. Cancer published by Wiley Periodicals LLC on behalf of American Cancer Society.)