1. Effective Foot‐and‐Mouth Disease Virus Control Using Silver Nanoparticles.
- Author
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Dung, Tran Thi Ngoc, Chi, Nguyen Thi Yen, Viet Quang, Dang, Thanh Cong, Nguyen, Lai, Thi Ngoc Ha, and Le, Van Phan
- Subjects
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FOOT & mouth disease , *SILVER nanoparticles , *VIRUS diseases , *PREVENTIVE medicine , *CYTOTOXINS , *RAMAN scattering - Abstract
This study investigates the antiviral efficacy of chitosan‐stabilized silver nanoparticles (AgNPs) against the Foot‐and‐Mouth Disease virus (FMDV), a highly contagious pathogen affecting cloven‐hoofed animals. In vitro experiments demonstrated that AgNPs effectively inhibited FMDV replication in a dose‐dependent manner. At a concentration of 1.56 μg/ml, AgNPs exhibited no cytotoxicity to baby hamster kidney 21 (BHK21) cells while achieving complete deactivation of FMDV at a titer of 103 TCID50 and inhibiting viral growth at a titer of 104 TCID50. These findings suggest the potential of silver nanoparticles as a novel disinfectant for controlling FMDV transmission and preventing disease outbreaks. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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