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A new clinical proceedings paper from the Clinical Neurological Society of America highlights the underrecognition of a neurological emergency called Nonconvulsive Status Epilepticus (NCSE). Unlike convulsive seizures, NCSE does not exhibit clear motor symptoms, making it difficult to diagnose and treat. This delay in treatment increases the risk of morbidity and mortality, with adults experiencing NCSE without convulsions having significantly higher mortality rates. The paper emphasizes the importance of using EEGs for proper diagnosis and emergency monitoring of NCSE. [Extracted from the article]

A study conducted by researchers at the University at Buffalo found that people with opioid use disorder who also have hepatitis C virus (HCV) were twice as likely to be successfully treated and cured from HCV if they received telemedicine treatment at their opioid treatment program (OTP) rather than being referred off-site. The study, published in the Journal of the American Medical Association (JAMA), is one of the few randomized controlled trials that have examined the effectiveness of telemedicine in improving healthcare access for vulnerable populations. The researchers found that 90.3% of participants in the telemedicine arm were cured of HCV infection compared to 39.4% of participants referred to an off-site specialist. The use of telemedicine also resulted in subsequent improvements in health and well-being for participants, including reductions in substance use. The study suggests that telemedicine should be further explored as an approach to increase healthcare access for underserved populations with other health conditions. [Extracted from the article]

A report from Complutense University Madrid discusses the current situation of tuberculosis in Spain. The report covers various aspects of the disease, including its incidence, populations most at risk, and healthcare for tuberculosis patients in Spain. It also explores topics such as latent tuberculosis, extrapulmonary disease, diagnosis methods, drug resistance, treatment duration, and special situations like tuberculosis in pediatric age and its implications in surgery and intensive care. The report also addresses the status of the BCG vaccine and the potential for new vaccines to eradicate the disease. Ethical and medicolegal implications of tuberculosis are also discussed. The research has been peer-reviewed. [Extracted from the article]

A recent report discusses research on behavior disorders in children. The report focuses on a paper by Frick (2022) that criticizes the use of the psychopathy construct in studying childhood disruptive behavior disorders (DBDs). While the paper cautions against using psychopathy components in the examination of DBDs, it argues that a multidimensional model of psychopathy could enhance our understanding of the etiology, mechanisms, prognosis, and treatment outcomes of DBDs. The research suggests that future studies should examine the broad construct of psychopathy to gain a better understanding of its relationship with DBDs. [Extracted from the article]

A recent study published in the medical journal Alzheimer's Research & Therapy found that a digital cognitive assessment called the Linus Health Digital Clock and Recall (DCR) test outperforms the commonly used paper-based Mini-Mental State Examination (MMSE) in detecting early signs of cognitive impairment and dementia. The DCR test is quick, sensitive, and accurate, and it provides data that can be used to assess a patient's cognitive functioning and predict their risk of developing dementia. The study also found that the DCR test is not influenced by ethnicity and can be administered in multiple languages, making it more equitable and accessible for diverse populations. [Extracted from the article]

A recent study conducted by researchers at Jamia Hamdard in New Delhi, India, has developed a 3D printed cassette integrated with a paper-based aptasensor for the detection of the dengue virus. The cassette, called '3DP-PAC', consists of an electrode cassette printed from a non-conductive filament and a chemically synthesized GO/ZnO-NC that increases the sensor's sensitivity. The aptasensor demonstrated selectivity for the dengue virus and performed well in human serum. This research opens up possibilities for the development of next-generation electrochemical biosensors using 3D printing technology for healthcare applications. [Extracted from the article]

A consensus paper from University Hospital in Charleroi, Belgium discusses the role of the cerebellum in human gait and its assessment and therapy. The cerebellum is critical for postural control and mapping sensory information into motor commands. Ataxia of stance/gait is a common symptom in cerebellar disorders and can lead to falls. The understanding of the cerebellar contribution to gait control can improve the management of cerebellar ataxias and potentially use gait parameters as biomarkers in future clinical trials. [Extracted from the article]

A report from the Royal Hospital for Children and Young People in Edinburgh, United Kingdom, discusses the potential benefits of stratified and precision nutrition in the management and prevention of inflammatory bowel disease (IBD). The report highlights the need for tailored dietary interventions based on an individual's characteristics, biology, gut microbiome, and environmental exposures. The research identifies four key themes: nutritional epidemiology for predicting IBD development, food-based dietary interventions, exclusive enteral nutrition for Crohn's disease management, and the use of pre- and probiotics for IBD management. However, the report concludes that there is currently insufficient evidence to make definitive recommendations for precision or stratified dietary therapy for patients with established IBD, and further research is needed to replicate early findings. [Extracted from the article]