22 results on '"COBALT TOXICITY"'
Search Results
2. Cobalt Uptake by Food Plants and Accumulation in Municipal Solid Waste Materials Compost-amended Soil: Public Health Implications.
- Author
-
Khan ZI, Ashfaq A, Ahmad K, Batool AI, Aslam M, Ahmad T, Mehmood N, Noorka IR, Gaafar AZ, Elshikh MS, Habib SS, Khan R, and Ugulu I
- Subjects
- Humans, Composting, Public Health, Soil Pollutants analysis, Vegetables chemistry, Vegetables metabolism, Plants, Edible chemistry, Plants, Edible metabolism, Cobalt analysis, Soil chemistry, Solid Waste analysis
- Abstract
One of the most pressing environmental issues is how to properly dispose of municipal solid waste (MSW), which represents both a substantial source of concern and a challenge. The current study evaluated cobalt (Co) accumulation in MSW, their uptake by different vegetables grown for two years, and related human health risks. Vegetables were grown in four different groups, such as one control (ground soil), and the remaining treatment groups (T1, T2, and T3) received varying concentrations of MSW. The analysis of Co was done through an atomic absorption spectrophotometer (AAS). Results revealed that the concentration of Co was higher in all the vegetables (n = 15) grown in soil supplemented with 75% MSW during 2nd growing year. Among all vegetables, the highest concentration of Co was observed in Solanum tuberosum at T3 during 2nd growing year. The pollution load index (PLI) value for vegetables during both growing years was more than 1 except in control soil. The findings indicated that the highest enrichment factor (EF) and hazard resilience index (HRI) value of 0.09 was present in S. tuberosum. Health index values for cobalt in the study were below 1. The HRI < 1 indicated that consumers do not face any immediate health risks. The investigation of Co concentrations in blood samples obtained from individuals residing in different areas contributes a human health perspective to the research. The findings indicate that the concentration of Co rises with an increasing proportion of MSW. While the metal levels in MSW-treated soil were not high enough to classify the soil as polluted, the results recommend that recycling MSW can substitute mineral fertilizers. Nevertheless, the presence of cobalt in MSW may directly affect soil fertility and could impact crop production and human health., (© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
- Published
- 2024
- Full Text
- View/download PDF
3. An Update Overview on Mechanistic Data and Biomarker Levels in Cobalt and Chromium-Induced Neurodegenerative Diseases.
- Author
-
Ajibo DN, Orish CN, Ruggieri F, Bocca B, Battistini B, Frazzoli C, Orish FC, and Orisakwe OE
- Subjects
- Humans, Animals, Oxidative Stress drug effects, Cobalt toxicity, Cobalt adverse effects, Chromium toxicity, Chromium adverse effects, Neurodegenerative Diseases chemically induced, Neurodegenerative Diseases metabolism, Biomarkers metabolism
- Abstract
There is increasing evidence that the imbalance of metals as cobalt (Co) and chromium (Cr) may increase the risk of development and progression of neurodegenerative diseases (NDDs). The human exposure to Co and Cr is derived mostly from industry, orthopedic implants, and polluted environments. Neurological effects of Co and Cr include memory deficit, olfactory dysfunction, spatial disorientation, motor neuron disease, and brain cancer. Mechanisms of Co and Cr neurotoxicity included DNA damage and genomic instability, epigenetic changes, mitochondrial disturbance, lipid peroxidation, oxidative stress, inflammation, and apoptosis. This paper seeks to overview the Co and Cr sources, the mechanisms by which these metals induce NDDs, and their levels in fluids of the general population and patients affected by NDDs. To this end, evidence of Co and Cr unbalance in the human body, mechanistic data, and neurological symptoms were collected using in vivo mammalian studies and human samples., (© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
- Published
- 2024
- Full Text
- View/download PDF
4. Assessing brain integrity in patients with long-term and well-functioning metal-based hip implants.
- Author
-
Taleb S, Varela-Mattatall G, Allen A, Haast R, Khan AR, Kalia V, Howard JL, MacDonald SJ, Menon RS, Lanting BA, and Teeter MG
- Subjects
- Humans, Male, Female, Middle Aged, Aged, Adult, Case-Control Studies, Hip Prosthesis, Brain diagnostic imaging, Chromium blood, Magnetic Resonance Imaging, Arthroplasty, Replacement, Hip, Cobalt blood
- Abstract
Production of metal debris from implant wear and corrosion processes is now a well understood occurrence following hip arthroplasty. Evidence has shown that metal ions can enter the bloodstream and travel to distant organs including the brain, and in extreme cases, can induce sensorial and neurological diseases. Our objective was tosimultaneously analyze brain anatomy and physiology in patients with long-term and well-functioning implants. Included were subjects who had received total hip or hip resurfacing arthroplastywith an implantation time of a minimum of 7 years (n = 28) and age- and sex-matched controls (n = 32). Blood samples were obtained to measure ion concentrations of cobalt and chromium, and the Montreal Cognitive Assessment was performed. 3T MRI brain scans were completed with an MPRAGE sequence for ROI segmentation and multiecho gradient echo sequences to generate QSM and R2* maps. Mean QSM and R2* values were recorded for five deep brain and four middle and cortical brain structures on both hemispheres: pallidum, putamen, caudate, amygdala, hippocampus, anterior cingulate, inferior temporal, and cerebellum. No differences in QSM or R2* or cognition scores were found between both groups (p > 0.6654). No correlation was found between susceptibility and blood ion levels for cobalt or chromium in any region of the brain. No correlation was found between blood ion levels and cognition scores. Clinical significance: Results suggest that metal ions released by long-term and well-functioning implants do not affect brain integrity., (© 2024 The Authors. Journal of Orthopaedic Research® published by Wiley Periodicals LLC on behalf of Orthopaedic Research Society.)
- Published
- 2024
- Full Text
- View/download PDF
5. Exposure to different cobalt chloride levels produces oxidative stress and lipidomic changes and affects the liver structure of Cyprinus carpio juveniles.
- Author
-
Bejaoui S, Chetoui I, Ghribi F, Belhassen D, Abdallah BB, Fayala CB, Boubaker S, Mili S, and Soudani N
- Subjects
- Animals, Lipidomics, Water Pollutants, Chemical toxicity, Malondialdehyde metabolism, Oxidative Stress drug effects, Carps, Cobalt toxicity, Liver drug effects
- Abstract
The present investigation was undertaken to evaluate the toxic effects of CoCl
2 -induced hepatotoxicity and fatty acid changes in juvenile Cyprinus carpio. Fish were divided into six experimental groups in duplicate. The first group served as controls. The second group received the lowest exposure dose at 2.5 µg/L. In the third group, fish were exposed to 25 µg/L of CoCl2 . The fourth group was exposed to 50 µg/L of CoCl2 . The last two groups were exposed to the highest doses, 100 and 500 µg/L of CoCl2 . Total antioxidant activities were estimated using a colorimetric method. Liver fatty acid compositions were analyzed by high-performance gas chromatography (GC). Hepatopathy was identified through microscopic analysis. Exposure of C. carpio to CoCl2 resulted in hepatotoxicity, indicated by increased levels of malondialdehyde (MDA), hydrogen peroxide (H2 O2 ), protein carbonyls (PCO), and alterations in the ferric reducing antioxidant power system (FRAP). Superoxide dismutase (SOD), glutathione-S-transferase (GST), glutathione peroxidase (GPx), reduced glutathione (GSH), metallothioneins (MTs), and low thiol levels (L-SH) significantly increased, particularly under exposure to the highest CoCl2 doses (100 and 500 µg/L). Acetylcholinesterase activity decreased significantly in C. carpio exposed to graded CoCl2 doses. Additionally, there was a decrease in polyunsaturated fatty acids (PUFA), primarily n-3 PUFA, docosahexaenoic acid (DHA), and eicosapentaenoic acid (EPA), while an increase in monounsaturated (MUFA) and saturated fatty acids (SFA), including palmitic (C16:0), stearic (C18:0), palmitoleic (C16:1), and oleic (C18:1) acids, was observed. Histopathological examination of the liver confirmed hepatopathy revealing characteristic tissue changes such as leucocyte infiltration, hepatic cell membrane degradation, vacuolization, and lipid inclusions. The study provided ethnophysiology insights into the responses of C. carpio to CoCl2 -induced oxidative stress and lipidomic alteration, underscoring its potential as a bioindicator for assessing environmental impacts and metal contamination., (© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)- Published
- 2024
- Full Text
- View/download PDF
6. Systemic Cobalt Toxicity Secondary to Metal-on-Metal Prosthetic Hip Replacement: a Case Report.
- Author
-
Blackmon, Jonathan, Blackmon, Lindsey, Goode, Claire, and Douthit, Nathan
- Subjects
MULTINUCLEATED giant cells ,TOTAL hip replacement ,COBALT - Abstract
This document provides information on the topic of cobalt toxicity in patients with metal-on-metal (MoM) hip implants. Cobalt toxicity can lead to various symptoms and complications, including peripheral neuropathy, hearing loss, cardiomyopathy, and hypothyroidism. The diagnosis involves elevated cobalt levels, confirmed findings consistent with cobalt toxicity, and exclusion of other causes. Treatment options include symptomatic management, chelation therapy, and revision of the MoM hip implant. Early detection is important for better outcomes. [Extracted from the article]
- Published
- 2024
- Full Text
- View/download PDF
7. Otologic Symptoms in 2 Patients with CobaltContaining Hip Prostheses.
- Author
-
Caballero-Borrego, Miguel, Turner, Martyn, and Larrosa, Francesc
- Subjects
PROSTHETICS ,RISK assessment ,TOTAL hip replacement ,NOISE-induced deafness ,SENSORINEURAL hearing loss ,CHELATING agents ,COBALT ,ARTIFICIAL implants ,MAGNETIC resonance imaging ,AUDIOMETRY ,CHROMIUM ,SURGICAL complications ,TINNITUS ,ACETYLCYSTEINE ,X-rays ,OTOTOXICITY ,HEARING disorders ,DISEASE risk factors ,EQUIPMENT & supplies ,SYMPTOMS - Abstract
Systemic poisoning related to cobalt–chromium total hip arthroplasty can affect multiple organs. In the otolaryngologic area the most frequent symptoms are tinnitus and hearing loss. In this report, we describe 2 patients with cobalt-containing hip prostheses who presented with otologic symptoms. The first case describes a patient with an extremely high cobalt blood level, which we believe may be one of the highest reported to date, after replacing a broken ceramic-on-ceramic prosthesis with a metal-on-metal prosthesis. This patient suffered all known complications associated with cobalt poisoning and survived. The second case, a female patient with a left resurfacing metal-on-metal prothesis, presented with bilateral continuous high-pitched tinnitus that started 8 months after surgery. Orthopedic surgeons and otologists should be vigilant for cobalt-induced ototoxicity in patients with metal-on-metal total hip prostheses. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
8. Exogenous application of sulfur-rich thiourea (STU) to alleviate the adverse effects of cobalt stress in wheat.
- Author
-
Zahid, Aiman, ul din, Kaleem, Ahmad, Muhamad, Hayat, Umer, Zulfiqar, Usman, Askri, Syed Muhammad Hassan, Anjum, Muhammad Zohaib, Maqsood, Muhammad Faisal, Aijaz, Nazish, Chaudhary, Talha, and Ali, Hayssam M.
- Subjects
COBALT ,THIOUREA ,PHOTOSYNTHETIC pigments ,HEAVY metals ,COBALT chloride - Abstract
Heavy metal stress affects crop growth and yields as wheat (Triticum aestivum L.) growth and development are negatively affected under heavy metal stress. The study examined the effect of cobalt chloride (CoCl
2 ) stress on wheat growth and development. To alleviate this problem, a pot experiment was done to analyze the role of sulfur-rich thiourea (STU) in accelerating the defense system of wheat plants against cobalt toxicity. The experimental treatments were, i) Heavy metal stress (a) control and (b) Cobalt stress (300 µM), ii) STU foliar applications; (a) control and (b) 500 µM single dose was applied after seven days of stress, and iii) Wheat varieties (a) FSD-2008 and (b) Zincol-2016. The results revealed that cobalt stress decreased chlorophyll a by 10%, chlorophyll b by 16%, and carotenoids by 5% while foliar application of STU increased these photosynthetic pigments by 16%, 15%, and 15% respectively under stress conditions as in contrast to control. In addition, cobalt stress enhances hydrogen peroxide production by 11% and malondialdehyde (MDA) by 10%. In comparison, STU applications at 500 µM reduced the production of these reactive oxygen species by 5% and by 20% by up-regulating the activities of antioxidants. Results have revealed that the activities of SOD improved by 29%, POD by 25%, and CAT by 28% under Cobalt stress. Furthermore, the foliar application of STU significantly increased the accumulation of osmoprotectants as TSS was increased by 23% and proline was increased by 24% under cobalt stress. Among wheat varieties, FSD-2008 showed better adaptation under Cobalt stress by showing enhanced photosynthetic pigments and antioxidant activities compared to Zincol-2016. In conclusion, the foliar-applied STU can alleviate the negative impacts of Cobalt stress by improving plant physiological attributes and upregulating the antioxidant defense system in wheat. [ABSTRACT FROM AUTHOR]- Published
- 2024
- Full Text
- View/download PDF
9. Data on Arthroplasty Reported by Researchers at University of Connecticut (Hyaluronic Acid-british Anti- Lewisite As a Safer Chelation Therapy for the Treatment of Arthroplasty- Related Metallosis).
- Subjects
CHELATION therapy ,RESEARCH personnel ,ARTHROPLASTY ,CHELATION ,TRANSITION metals ,FATIGUE limit - Abstract
Researchers at the University of Connecticut have developed a safer chelation therapy for the treatment of metallosis related to arthroplasty. Metallosis occurs when cobalt ions are released from cobalt-containing prosthetics used in hip replacements, leading to toxic effects in the body. The researchers designed a chelator called BAL-HA, which effectively binds cobalt ions and enhances their clearance from the body. This noninvasive therapy has the potential to mitigate cobalt toxicity and reduce the need for revision surgeries. [Extracted from the article]
- Published
- 2024
10. Occupational, environmental, and toxicological health risks of mining metals for lithium-ion batteries: a narrative review of the Pubmed database.
- Author
-
Brown, Connor W., Goldfine, Charlotte E., Allan-Blitz, Lao-Tzu, and Erickson, Timothy B.
- Subjects
ELECTRIC power supplies to apparatus ,RISK assessment ,MANGANESE ,HEALTH status indicators ,ACUTE diseases ,COBALT ,RESPIRATORY diseases ,SYSTEMATIC reviews ,MEDLINE ,LITHIUM ,NICKEL ,NEUROLOGICAL disorders ,CHRONIC diseases ,OCCUPATIONAL exposure ,ENVIRONMENTAL exposure ,MINERAL industries ,METALS ,ONLINE information services ,COMPARATIVE studies - Abstract
Background: The global market for lithium-ion batteries (LIBs) is growing exponentially, resulting in an increase in mining activities for the metals needed for manufacturing LIBs. Cobalt, lithium, manganese, and nickel are four of the metals most used in the construction of LIBs, and each has known toxicological risks associated with exposure. Mining for these metals poses potential human health risks via occupational and environmental exposures; however, there is a paucity of data surrounding the risks of increasing mining activity. The objective of this review was to characterize these risks. Methods: We conducted a review of the literature via a systematic search of the PubMed database on the health effects of mining for cobalt, lithium, manganese, and nickel. We included articles that (1) reported original research, (2) reported outcomes directly related to human health, (3) assessed exposure to mining for cobalt, lithium, manganese, or nickel, and (4) had an available English translation. We excluded all other articles. Our search identified 183 relevant articles. Results: Toxicological hazards were reported in 110 studies. Exposure to cobalt and nickel mining were most associated with respiratory toxicity, while exposure to manganese mining was most associated with neurologic toxicity. Notably, no articles were identified that assessed lithium toxicity associated with mining exposure. Traumatic hazards were reported in six studies. Three articles reported infectious disease hazards, while six studies reported effects on mental health. Several studies reported increased health risks in children compared to adults. Conclusions: The results of this review suggest that occupational and environmental exposure to mining metals used in LIBs presents significant risks to human health that result in both acute and chronic toxicities. Further research is needed to better characterize these risks, particularly regarding lithium mining. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
11. Cobalt exposure and pulmonary function reduction in chronic obstructive pulmonary disease patients: the mediating role of club cell secretory protein.
- Author
-
Tang, Fei, Liu, Hong-Yan, He, Qi-Yuan, Liu, Ying, Lv, Li-Ping, Fei, Jun, and Fu, Lin
- Subjects
POISONS ,CHRONIC obstructive pulmonary disease ,CONCENTRATION functions ,LUNGS ,ENVIRONMENTAL exposure - Abstract
Background: Cobalt (Co) is a metal which is widely used in the industrial production. The previous studies found the toxic effects of environmental Co exposure on multiple organs. However, the correlation of blood Co concentration with lung function was inconsistent in patients with chronic obstructive pulmonary disease (COPD). Methods: All 771 stable COPD patients were recruited. Peripheral blood and clinical information were collected. The levels of blood Co and serum CC16 were measured. Results: Cross-sectional study suggested that the level of blood Co was inversely and dose-dependently related to lung function parameters. Each 1 ppm elevation of blood Co was related to 0.598 L decline in FVC, 0.465 L decline in FEV1, 6.540% decline in FEV1/FVC%, and 14.013% decline in FEV1%, respectively. Moreover, higher age, enrolled in winter, current-smoking, higher smoking amount, and inhaled corticosteroids prominently exacerbated the negative correlation between blood Co and lung function. Besides, serum CC16 content was gradually reduced with blood Co elevation in COPD patients. Besides, serum CC16 was positively correlated with lung function, and inversely related to blood Co. Additionally, decreased CC16 substantially mediated 11.45% and 6.37% Co-triggered downregulations in FEV1 and FEV1%, respectively. Conclusion: Blood Co elevation is closely related to the reductions of pulmonary function and serum CC16. CC16 exerts a significantly mediating role of Co-related to pulmonary function decrease among COPD patients. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
12. Cobalt Serum Level as a Biomarker of Cause-Specific Survival among Prostate Cancer Patients.
- Author
-
Pietrzak, Sandra, Marciniak, Wojciech, Derkacz, Róża, Matuszczak, Milena, Kiljańczyk, Adam, Baszuk, Piotr, Bryśkiewicz, Marta, Sikorski, Andrzej, Gronwald, Jacek, Słojewski, Marcin, Cybulski, Cezary, Gołąb, Adam, Huzarski, Tomasz, Dębniak, Tadeusz, Lener, Marcin R., Jakubowska, Anna, Kluz, Tomasz, Soroka, Marianna, Scott, Rodney J., and Lubiński, Jan
- Subjects
RESEARCH funding ,PROSTATE tumors ,CAUSES of death ,COBALT ,TUMOR markers ,MULTIVARIATE analysis ,DESCRIPTIVE statistics ,LONGITUDINAL method ,ODDS ratio ,STATISTICS ,CANCER patient psychology ,CONFIDENCE intervals ,REGRESSION analysis - Abstract
Simple Summary: Prostate cancer is the most common cancer detected among men and it is the second leading cause of death. According to the WHO, cobalt is probably involved in carcinogenesis. However, there are no studies related to cobalt levels and survival in prostate cancer patients. The aim of this prospective study was to investigate the relationship between serum cobalt levels and survival among prostate cancer patients taking into consideration prostate cancer-specific deaths and non-cancer causes of death. Our findings, based on 261 Polish prostate cancer patients, show that individuals with high serum cobalt levels have a significantly worse survival compared to participants with low serum cobalt levels. Prostate cancer is the most common cancer diagnosed in men and the second leading cause of death in male cancer patients. The WHO suggests that cobalt is involved in the carcinogenesis of prostate cancer. There are, however, no studies associating cobalt levels and prostate cancer patient survival. In this study, 261 Polish prostate cancer (n = 261) patients were recruited into a prospective cohort between 2009 and 2015. Serum cobalt levels were measured using ICP-MS after prostate cancer diagnosis and before treatment. All study participants were assigned into quartiles (QI-QIV) based on the distribution of serum cobalt levels among censored patients. Univariable and multivariable COX regression models were used to calculate hazard ratios (HRs) for each serum cobalt level quartile. We found a significant relationship between high serum cobalt levels and poor prostate cancer patient total survival (HR = 2.60; 95% CI: 1.17–5.82; p = 0.02). In relation to prostate cancer patients who died as a result of other non-cancer causes, the association with high levels of cobalt was even stronger (HR = 3.67; 95% CI: 1.03–13.00; p = 0.04). The impact of high serum cobalt levels on overall survival of prostate cancer-specific-related deaths was not statistically significant. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
13. Onion Peel: A Promising, Economical, and Eco-Friendly Alternative for the Removal of Divalent Cobalt from Aqueous Solutions.
- Author
-
Lizcano-Delgado, Yehudy Yelitza, Martínez-Vázquez, Osiris Tais, Cristiani-Urbina, Eliseo, and Morales-Barrera, Liliana
- Subjects
AQUEOUS solutions ,SUSTAINABILITY ,ONIONS ,COBALT ,ANALYTICAL chemistry - Abstract
There is a growing need for an economical and efficient method capable of removing heavy metals from residual water. The current contribution aimed to evaluate the capacity of onion peel, an abundant agroindustrial waste product, to remove divalent cobalt (Co
2+ ) from aqueous solutions. Onion peel was submitted to proximal chemical analysis, and various operational factors involved in biosorption were tested. The most suitable temperature (30 °C), pH (7.0), and biosorbent particle size (300–800 µm) were found. With an initial Co2+ concentration of 380 mg L−1 , the maximum capacity of Co2+ removal was 59.88 mg g−1 in 120 min. The pseudo-second order and Langmuir models provided the best fit to the experimental kinetics and equilibrium of Co2+ biosorption, respectively. The thermodynamic study evidenced an exothermic, non-spontaneous, and favorable reaction (ΔH0 = −5.78 kJ mol−1 ; ΔS0 = −21.13 J mol−1 K−1 ), suggesting the formation of stable bonds in the biosorbent-Co2+ complex. The carbonyl and hydroxyl groups apparently play a fundamental role in Co2+ removal, and electrostatic attraction, ion exchange, and chemisorption are the principal mechanisms. Thus, the biosorption of Co2+ by onion peel has potential as an economical, eco-friendly, efficient, and sustainable treatment for wastewater. [ABSTRACT FROM AUTHOR]- Published
- 2024
- Full Text
- View/download PDF
14. Protective effect of cinnamon extract against cobalt-induced multiple organ damage in rats.
- Author
-
Isik, Bahar, Suleyman, Bahadir, Mammadov, Renad, Bulut, Seval, Yavuzer, Bulent, Altuner, Durdu, Coban, Taha Abdulkadir, and Suleyman, Halis
- Subjects
ASPARTATE aminotransferase ,CINNAMON ,BLOOD urea nitrogen ,RATS ,TROPONIN I ,ALANINE aminotransferase - Abstract
Background: The role of oxidative stress and inflammation in cobalt (Co) toxicity has been the focus of previous studies. Cinnamon and its main components have been reported to have protective effects in various tissues with antioxidant and anti-inflammatory effects. Aims: In this study, the protective effect of cinnamon extract (CE) against possible Co-induced heart, kidney, and liver damage in rats was investigated biochemically. Methods: Eighteen albino Wistar-type male rats were categorized into three groups (n = 6 per group): control (CG), CoCL2-administered (CoCL2), and CE + CoCL2-administered (CE + Co) groups. The CE + CoCL2 group was administered CE (100 mg/kg), and the CoCL2 and CG groups were administered distilled water orally by gavage. One hour after the administration, Co (150 mg/kg) was administered orally to the CE + CoCL2 and CoCL2 groups. This procedure was repeated once daily for 7 days. Then, biochemical markers were studied in the excised heart, kidney, and liver tissues. Results: CoCL2 increased oxidants and proinflammatory cytokines and decreased antioxidants in heart, kidney, and liver tissues. Heart, kidney, and liver tissue were affected by Co damage. CE treatment suppressed the CoCL2-induced increase in oxidants and proinflammatory cytokines and decrease in antioxidants in heart, kidney, and liver tissues. CE treatment has been shown to attenuate cardiac damage by reducing serum troponin I (TpI) and creatine kinase-MB (CK-MB), renal damage by reducing creatinine and blood urea nitrogen (BUN), and liver damage by reducing alanine aminotransferase (ALT) and aspartate aminotransferase (AST). Conclusion: Co induced the production of oxidants and proinflammatory parameters and antioxidant depletion in heart, kidney, and liver tissues of rats. Our experimental results show that CE protects heart, kidney, and liver tissues against oxidative and inflammatory changes induced by CoCLl2. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
15. Removal of Cobalt Metal Ion from Aqueous Solution using Punica granatum Stem Powder as Biosorbent.
- Author
-
Kharde, Harshal S., Maurya, Champa, and Aher, Haribhau R.
- Subjects
METAL ions ,AQUEOUS solutions ,POMEGRANATE - Abstract
Natural agricultural solid waste material is very cost-effective for synthesizing adsorbents utilized in the removal of heavy metal ion from economic and noneconomic wastewaters, which are numerously exploded in environmental soil and water resources. Punica granatum (pomegranate) stem powder (PGSP) was synthesized into nanoparticle size and practiced in the removal of cobalt metal ions. The adsorbent was synthesized in a greener manner in an aqueous medium. A batch adsorption study was carried out with parameters including the effect of pH (pH 4, 73.13%), adsorbent dose (200 mg, 70.80%), the concentration of metal ion (200 ppm, 81.56%) and effect of temperature (30°C, 71.56%). Characterization study of PGSP before cobalt metal ion adsorption and after cobalt metal ion adsorption was conducted, including scanning electron microscopy, transmission electron microscopy, X-ray diffraction analysis, fourier transform infrared spectroscopy, ultraviolet-visible spectroscopy and elemental detection analysis. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
16. Too young for an acquired cardiomyopathy? Cobalt metallosis as a cardiac amyloidosis mimicker.
- Author
-
Casian, Mihnea, Bica, Ramona, Ionescu, Virgil, Predescu, Vlad, Țincu, Radu, and Jurcuț, Ruxandra
- Subjects
CARDIAC amyloidosis ,COBALT ,LEFT ventricular hypertrophy ,CONGENITAL hip dislocation ,CARDIOMYOPATHIES ,TOTAL hip replacement ,CHELATING agents - Abstract
Metallosis with subsequent cardiac involvement is a possible long‐term complication of hip arthroplasty. We report the case of a young female referred to our centre for the suspicion of cardiac amyloidosis presenting with low electrocardiogram voltage, left ventricular hypertrophy, pericardial effusion, and global and longitudinal systolic impairment with apical sparing pattern. Her medical history was remarkable for arthroplasty in the context of congenital hip dysplasia. Two years prior to presentation, she underwent revision surgery for prosthesis malfunction, and tissue metallosis was initially documented. At the current presentation, cobalt metallosis was confirmed, as the circulating cobalt and chromium levels were severely elevated. The accurate diagnosis prompted the removal of the cobalt source with extensive tissue debridement and the use of chelating agents. Reversal of the cardiac abnormalities occurred as the circulating cobalt levels returned to normal. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
17. Model-Assisted Optimization of Cobalt Biosorption on Macroalgae Padina pavonica for Wastewater Treatment.
- Author
-
Aloufi, Abeer S., Al Riyami, Bahja, Fawzy, Mustafa A., Al-Yasi, Hatim M., Koutb, Mostafa, and Hassan, Sedky H. A.
- Subjects
LEAD removal (Water purification) ,WASTEWATER treatment ,FOURIER transform infrared spectroscopy ,COBALT ,RESPONSE surfaces (Statistics) ,GIBBS' free energy - Abstract
The release of heavy metals into the environment as a result of industrial and agricultural activities represents one of the century's most significant issues. Cobalt is a hazardous metal that is employed in a variety of industries. In this study, response surface methodology (RSM) combined with Box–Behnken design (BBD) was utilized to optimize the Co(II) ion removal from synthetic wastewater by the brown macroalga Padina pavonica. The influence of three factors, namely algal inoculum size, pH, and initial metal concentration, was assessed in optimization studies. RSM proposed a second-order quadratic model with a p-value of <0.0001 and R
2 of 0.984 for P. pavonica. According to the data related to RSM optimization, the maximum percentage of Co(II) removal of 84.3% was attained under the conditions of algal inoculum size of 5.98 g/L, pH of 6.73, and initial Co(II) concentration of 21.63 mg/L. The experimental data from the biosorption process were fitted well with the Langmuir, Freundlich, and Temkin isotherm models. The maximal Co(II) adsorption capacity was estimated using the Langmuir model to be 17.98 mg/g. Furthermore, the pseudo-second-order kinetic model was shown to have the best fit for Co biosorption by P. pavonica, showing that the mechanism of Co(II) biosorption was chemisorption controlled by surface biosorption and intra-particle diffusion. Thermodynamic parameters were also investigated to evaluate the Gibbs free energy for the Co(II) ion, which was positive, showing that the biosorption process is nonspontaneous and exothermic, and the cobalt biosorption rate decreases with increasing temperature. Algal biomass was characterized by Fourier transform infrared spectroscopy, scanning electron microscopy, and energy dispersive spectroscopy. These analyses revealed the biosorbent's diverse functional groups and porous, rough appearance. Therefore, P. pavonica can be used to implement sustainable, eco-friendly, and acceptable solutions to water pollution problems. [ABSTRACT FROM AUTHOR]- Published
- 2024
- Full Text
- View/download PDF
18. Removing Heavy Metals: Cutting-Edge Strategies and Advancements in Biosorption Technology.
- Author
-
Staszak, Katarzyna and Regel-Rosocka, Magdalena
- Subjects
HEAVY metals ,INDUSTRIAL wastes ,COPPER ,POLLUTANTS ,SEWAGE ,CHEMICAL decomposition ,CHROMIUM removal (Water purification) ,LEAD removal (Sewage purification) - Abstract
This article explores recent advancements and innovative strategies in biosorption technology, with a particular focus on the removal of heavy metals, such as Cu(II), Pb(II), Cr(III), Cr(VI), Zn(II), and Ni(II), and a metalloid, As(V), from various sources. Detailed information on biosorbents, including their composition, structure, and performance metrics in heavy metal sorption, is presented. Specific attention is given to the numerical values of the adsorption capacities for each metal, showcasing the efficacy of biosorbents in removing Cu (up to 96.4%), Pb (up to 95%), Cr (up to 99.9%), Zn (up to 99%), Ni (up to 93.8%), and As (up to 92.9%) from wastewater and industrial effluents. In addition, the issue of biosorbent deactivation and failure over time is highlighted as it is crucial for the successful implementation of adsorption in practical applications. Such phenomena as blockage by other cations or chemical decomposition are reported, and chemical, thermal, and microwave treatments are indicated as effective regeneration techniques. Ongoing research should focus on the development of more resilient biosorbent materials, optimizing regeneration techniques, and exploring innovative approaches to improve the long-term performance and sustainability of biosorption technologies. The analysis showed that biosorption emerges as a promising strategy for alleviating pollutants in wastewater and industrial effluents, offering a sustainable and environmentally friendly approach to addressing water pollution challenges. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
19. Differential interactions of essential and toxic metal ions with biologically relevant phosphatidic acid and phosphatidylserine membranes
- Author
-
Issler, Travis, Sule, Kevin, Lewrenz, Anna-Marie, and Prenner, Elmar J.
- Published
- 2024
- Full Text
- View/download PDF
20. Data on Arthroplasty Reported by Researchers at University of Connecticut (Hyaluronic Acid-british Anti- Lewisite As a Safer Chelation Therapy for the Treatment of Arthroplasty- Related Metallosis)
- Subjects
Hyaluronic acid ,Arthroplasty ,Gases, Asphyxiating and poisonous -- War use ,Cobalt ,Physical fitness ,Health ,University of Connecticut ,National Academy of Sciences - Abstract
2024 FEB 3 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Current study results on Surgery - Arthroplasty have been published. According to [...]
- Published
- 2024
21. Congo-Kinshasa: 'We Miners Die a Lot.' Appalling Conditions and Poverty Wages - the Lives of Cobalt Miners in the DRC
- Subjects
Cobalt industry ,Mineral industry ,Working women ,Mining industry ,Cobalt ,Wages ,Mine accidents ,Natural resources -- China -- Sub-Saharan Africa -- Congo (Kinshasa) ,Salary ,News, opinion and commentary - Abstract
Byline: Roy Maconachie It was a cool, dusty morning in July 2021, when I first visited the Kamilombe cobalt mine in Lualaba Province in south-eastern Democratic Republic of Congo. Situated [...]
- Published
- 2024
22. Data on Nanoparticles Reported by Researchers at King Saud University (Cobalt-based Nanoparticles Strongly Diminish Calceinam Fluorescence Independently of Their Cytotoxic Potential In Human Lung Cell Line)
- Subjects
Nanoparticles ,Fluorescence ,Nanotechnology ,Cobalt ,Biological sciences ,Health ,King Saud University - Abstract
2024 JAN 2 (NewsRx) -- By a News Reporter-Staff News Editor at Life Science Weekly -- Investigators publish new report on Nanotechnology - Nanoparticles. According to news reporting out of [...]
- Published
- 2024
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.