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Cave studies enable us to unravel valuable information on landscape evolution. In glacial settings, the glacial cycles induced fluctuations in the underground hydraulic regime, sediment availability and base level in adjacent caves. Here, we present our work on the Grønli-Seter cave system in Northern Norway, which comprises >8 km of passage length at an elevation between 250 m and present sea level. By linking cave morphology and deposits to shifting glacier configurations and external base level changes during the last deglaciation and the Early Holocene, we establish how the hydraulic conditions in the cave system shifted in pace with glacier fluctuations. Maze sections and phreatic loops appear in a hydraulic confined setting close to the interface between the calcite marble and the overlying mica schist. Scallops in the cave walls demonstrate slow, ascending water flow, evidence of subglacial speleogenesis under wet-based, topographically constrained glaciers with a gentle surface slope. Moreover, cave morphology and clastic deposits indicate various hydrological phases of descending water flow, stagnant conditions, and excessive flow rates. Our work establishes that the last glaciation and deglaciation had an insignificant effect on the cave system's solutional development. In contrast, the cave sediments reveal diverse hydraulic conditions that may be related to shifting glacier configurations. This research offers valuable insights into glacier ice-contact speleogenesis and landscape development in glacial terrains. [Display omitted] • Reveal the relationship between cave morphology, deposits and glacier fluctuations. • Relate ice-contact speleogenesis to the glacial valley development. • Identify shifting hydrological conditions in the caves during the last deglaciation. [ABSTRACT FROM AUTHOR]