A comprehensive review from the University of Padua in Italy highlights the importance of multimodality imaging techniques in the diagnosis, management, and follow-up of advanced heart failure (AHF). These techniques, including echocardiography, cardiac magnetic resonance imaging (CMR), nuclear imaging, and cardiac computed tomography (CCT), play a crucial role in patient care, device selection and monitoring, and the assessment of orthotopic cardiac transplant (OTC) patients. By integrating diverse imaging modalities, clinicians gain a panoramic understanding of each patient's condition, leading to well-informed decisions and improved patient outcomes. This review emphasizes the irreplaceable role of multimodality imaging in advanced heart failure management. [Extracted from the article]