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Natural products are a marvel of evolution. Plants are chemical factories and have produced a vast number of highly diverse and interesting natural substances with their extraordinary properties, which we humans have been using for centuries to relieve and cure diseases. At the latest since the discovery of penicillin, natural substances have become an important source of medicines, but we know only very few of the presumably many millions that are still waiting to be discovered. Important antibiotics, immunosuppressants, anticancer agents, hormones, and antiviral agents are among the natural products. But do natural products still matter in the age of biotechnology and genetic engineering? Yes, more than ever, because medicinal chemists draw creative inspiration for their syntheses from nature to develop the next blockbuster in medicine. Oliver Kayser tells the story of natural products and medicinal plants in this book in a highly informative and amusing way from a new perspective. He explores how natural products from naturopathy gave birth to the pharmaceutical industry, how they shaped our society as medicines and remedies, enabled wars, and paved the way to Nobel Prizes. The author paints a fascinating panorama of natural product chemistry in plants, microorganisms, and animals. Starting with the first isolations at the beginning of the industrial revolution, he leads us with the ideas and enthusiasm of many scientists into the modern era of drug testing, computer chemistry, and the highly successful serendipitous discoveries of active ingredients. Natural product research in the laboratory has an enormous impact on our lives today. The author offers a glimpse over the shoulder of how the search for the new drugs of tomorrow works today. This book is the ultimate book from the pen of a scientist deeply rooted in research, providing the reader with an enlightening and at the same time entertaining insight into how scientists think and how arduous research can be.

This book conducts research on the evaluation and reduction mechanism of the negative effects of urban Transportation Energy Supply Network (TESN). By analyzing the current supply and demand situation of urban transportation energy supply network, the concept of negative effects of urban transportation energy supply network is defined, and specific definitions and measurement methods of negative effects are proposed. A TESN negative effect reduction mechanism was constructed from three aspects: site layout optimization, site cooperation game, and replenishment vehicle scheduling. The simulation validation of the urban transportation energy supply network was conducted using AnyLogic simulation software.

Scientific writing is a trade that can and must be learned and not a form of art that is limited to the talented. The real constraint for writing a good scientific article is most of the time not the usage of the English language, but the conversion of outcomes of a set of experiments into a coherent and convincing scientific story. This book is designed to guide junior scientists in the Life Sciences writing their thesis and first manuscripts, along this uphill struggle. All aspects of building up and publishing a forceful scientific narrative are covered, from designing experiments to dealing with the reviewers'comments. This book takes you step by step through the process of writing a paper. It starts by discussing how to collect and organize data and make an outline. The actual writing starts with the Results section, as this is the heart of any research paper. The Discussion interprets your data in the framework of the existing literature and explains the novel insights you obtained. The Introduction is written to pose the questions that are answered in the Discussion and give the necessary background information. It is written after the Results and Discussion to make sure it is a perfect match. The M&M is the easiest to write. A good abstract is essential for attracting readers. How to write that is described in detail. The title is the last piece of the puzzle. The book contains many practical examples that explain the general principles of good writing. These examples are all from the Life Sciences and so are the anecdotes that illustrate the concepts, making the information directly applicable. All kinds of tips and suggestions are provided for improving readability and accessibility of your manuscript, thus making it easier acceptable. In addition, background information on the basics of science is supplied that helps to avoid common mistakes that cause rejection of manuscripts that report on otherwise good science.

Industrial crops offer farmers new market opportunities to increase their revenue by producing high-value products, focusing on fiber, forest, and energy crops, industrial oilseeds, rubber and resins, pharmaceuticals, and more. Technological innovations in agriculture have facilitated higher yields, but conserving crop genetic resources and diversity remains crucial for sustainable agricultural production. This poses a challenge that can be addressed through modern tools of biotechnology and genomics, utilizing the wealth of sequenced plant genomes. This book addresses the need for knowledge in managing the risks and conservation of genetic diversity associated with advanced technology. It provides comprehensive coverage of plant genomics and biotechnology, catering to post-graduate students, researchers, employees of seed and biotechnology companies, as well as instructors in plant genetics, breeding, and biotechnology fields.

A concise and engaging biology text for biology majors, Understanding Biology 4e partnered with Connect emphasizes fundamentals concepts to help students better understand biology and focus on developing scientific skills. This approach utilizes the Vision and Change guidelines of Core Concepts and Core Skills while helping students begin the process of becoming a scientist.

Antimicrobial peptides (AMPs) have been sought to be a potential alternative to the current arsenal of antibiotics against undesirable microbes. AMPs synthesized by lactic acid bacteria have attracted significant attention due to their strong activity against a broad range of bacteria including pathogens. The bacteriocin (an AMP) has been known to us since early 1928, a year before penicillin was reported. This is possibly due to their narrower activity compared to antibiotics. However, several AMPs having promising activity have been thoroughly characterized in the past few decades. Renewed interest has developed focusing on industrially important bacteriocins produced by lactic acid bacteria. Some of these AMPs are also active against food spoilage and clinically important pathogens. Similar to antibiotics, large-scale intellectual screening is ongoing in the search for novel AMPs with unique properties. Recent research has revealed that AMPs may also play a role in maintaining gut microflora and keeping us protected from food-borne pathogens. The ongoing genomic studies suggest that there may be more such bioactive compounds waiting to be explored. This book provides an overview of the fundamental knowledge accumulated so far regarding the diversity and potential applications of AMPs produced by lactic acid bacteria. This updated reference book on AMPs from lactic acid bacteria is timely, covering the most important achievements in the field and providing the scientific community particularly graduate students, researchers, and clinicians with the latest updates. The goal of this book is to illustrate and detail the findings made so far, debate the state of the art, and draw new perspectives.

The book explains the use of natural products as scaffolds in tissue engineering. It presents an introduction to the concept of natural product-based scaffolds and explores various fabrication strategies for their synthesis. The book highlights the wide range of applications of these scaffolds in tissue engineering, including their use in tissue regeneration, wound healing, plastic surgery, and breast reconstruction. Specific natural products, such as gums (xanthan, gellan, arabic, guar, ghatti gum), chitosan, collagen are discussed in separate chapters. In addition, various application of natural product loaded PCL and PLA scaffolds have also been discussed. Each chapter focuses on the application of these natural product based scaffolds and explores their potential in tissue engineering. It also covers specific applications of these scaffolds in tissue regeneration, including angiogenesis, bone, skin, and nerve tissue regeneration. The book addresses important considerations regarding the toxicity and regulatory aspects of natural product-based scaffolds and explores the challenges associated with their implementation and emphasizes the need for safety and compliance in their use. Overall, the book provides a comprehensive overview of the field. It serves as a valuable resource for researchers, scientists, and professionals in the field of tissue engineering.

This book provides insights into the recent developments in the field of bioprocess technology and bioreactor design. Bioprocess engineering or biochemical engineering is a subcomponent of chemical engineering, which encompasses designing and developing those processes and equipment that are required for the manufacturing of products from biological materials and sources, such as agriculture, pharmaceutical, chemicals, polymers, food, etc., or for the treatment of environmental process, for example, waste water. The main focus of this book is to highlight the advancements in the field of bioprocess technology and bioreactor design. The book is divided into various chapters briefing all aspects of bioprocess engineering and focusing on the advances in bioprocess engineering. The book summarizes introduction to bioprocess technology and microbiology, isolation and maintenance of microbial strains, and sterilization techniques for advanced-level students and researchers. Different models depicting kinetics of microbial growth, substrate consumption, and product formation are discussed. The applications of enzymes have increased tremendously and therefore understanding their metabolic pathways to increase yields is also briefly discussed. The calculations of mass and energy balances associated with entropy changes and free energy. This book also covers the approaches for handling different types of cell cultures and current advancements in the area of bioprocess strategies for different culture types, which scientists and researchers working in the different cell cultures can refer to. The downstream processing of various industrially important products is also a part of this book. Apart from that, the process economics which ensures the feasibility and quality of any biological process is also dealt with as the last section of the book.

Emergence of lifestyle diseases, e.g., type II diabetes, cancers, obesity, cardiovascular disorders, liver cirrhosis, etc., are exponentially increasing day by day. Modern drifts toward the utilization of herbal medicines in different healthcare aspects necessitate (demand) the replacement of synthetic molecules with phytoconstituents because of their biocompatibility, biodegradability, economic extraction process, and ready availability from the natural source. This book provides a thorough insight into the comprehensive and up-to-date trends of phytomedicines in the management of lifestyle diseases and its mechanisms, modern methods of extraction and purification of phytoconstituents, and chemical characterization as well as standardization of phytoconstituents using modern equipments.

This book provides technical information on different biological and hybrid wastewater treatment systems for treatment of wastewater and reuse. The contained information helps in tracking their progress of such systems toward practical and field-scale applications. The book also includes strategies to be adopted for minimizing the losses and maximizing the benefits. Additionally, it includes methods for protecting the environment through the application of advanced biological and hybrid wastewater treatment technology. Furthermore, it discusses the crucial parts that science, technology, and innovation play in the formulation, implementation, and administration of wastewater treatment policy. It highlights the challenges that must be overcome to adopt biological and hybrid wastewater treatment infrastructure regulations successfully and provides some answers. It investigates how the biological and hybrid wastewater treatment technology may be used in a wide variety of field's sets apart from other on-the-shelf publications on the market. Also, it delves into the core concepts of biological and hybrid wastewater treatment systems. It explores how these concepts can be modified to fit a variety of contexts and uses. Applications such as managing facilities, dealing with pandemics, urban wastewater treatment and reuse, farming, and other applications are included in this book. This book is helpful to researchers, entrepreneurs, professionals, planners, policymakers, environmental engineers, and others interested in biological and hybrid wastewater treatment system management strategies through the application of breakthroughs in biological and hybrid wastewater treatment technologies. Also, it is useful as a fundamental source of information and state-of-the-art knowledge to graduate students, university faculties, and researchers in the fields of environmental sciences/engineering, biological and chemical sciences, and NGO. It is also useful to entrepreneurs, professionals, and planners in policy and decision making at the local, state, and national levels for many countries.

The Living World is often considered a studentfavorite, focusing on concepts rather than terminology and technicalinformation. It features a straightforward,conversational writing style and a wide variety of media assets to enhance thecontent of the textbook. Every chapter of this 11th edition focuses directly onthe relevance of its content to today's students. The 11th edition of TheLiving World includes contributions and pedagogy from new coauthor, Dr.Joel Bergh.

The book introduces readers to the latest developments in biotechnological methods used for improving the cultivation of silkworms. The text focuses on implementing biotechnological approaches, ranging from basic to advanced techniques, on enhancing silk production, increasing abiotic stress resilience, improving disease tolerance, and developing resistance in silkworm crops. With the current climate crisis and growing demand for high-quality silk, biotechnological applications have become essential in addressing the urgent need to increase silk production. The field of sericulture has made significant breakthroughs, such as identifying DNA markers, linkage association, genome-wide association studies, generating mutants, and introducing transgenic silkworms. Developing silkworms with improved cocoon yield and disease resistance is crucial to boost silk production. The book covers fundamental principles and recent advancements and delves into various methodologies employed inseri-biotechnology for improving silkworm crops. These methodologies include next-generation sequencing for DNA sequencing, using molecular markers to enhance abiotic stress tolerance (specifically high temperature and humidity conditions), expression analysis, RNA interference, gene knockout approaches to bolster disease resistance, and transcriptomics to enhance economically significant parameters such as silk content. The book explains these topics in detail and includes contemporary research appraisals, extensive discussions, and an evaluation of the benefits and risks associated with the use of biotechnological tools. This book serves as an invaluable reference for researchers and academics in biotechnology, molecular biology, and sericulture while also serving as an informative starting point for budding researchers.

Biology is a traditional, comprehensive introductory biology textbook with coverage from cell structure and function to the conservation of biodiversity and is appropriate for a one- or two-semester biology course. Biology focuses on three themes: systems, evolution, and the nature of science. These themes are integrated into all aspects of the textbook, from the unit learning outcomes to the theme-based feature readings in the text. Recognizing that instructors are increasingly being asked to engage their students while still providing them with a firm foundation in core biological principles, the authors of Biology integrated relevant content throughout the text to better allow students to make connections and think more scientifically.

This book focuses on the various applications of microorganisms for sustainable environment and the reduction of hazardous pollutants released in various forms, including xenobiotics, e-waste, pesticides, insecticides, plastic, heavy metals, paper waste, medical waste, textile dyes, and their impact on environmental and human health. The book involves a series of research reports that explain the application of microbes used to solve real-life issues raised due to changes happening in environment, including pollution, by covering applications, including the use of bacteria, fungi, microalgae and biofilm in the detection and degradation of crude oil, pesticides, dyes, e-waste, heavy metals and other pollutants. It also focuses on integrative strategies in the application of microbial nanomaterials for remediation of pollutant. This material will help environmental scientists and microbiologists to learn about existing environmental problems and suggest novel ways to control or contain their effects by employing various treatment approaches.

Blockchain is a new type of technology that combines and secures information exchange between different stakeholders such as medical practitioners, patients, healthcare providers, and other applicable parties. Among them, Blockchain Technology is one of the most important areas in the bioinformatics application of biomedical research and healthcare systems utilizing unique requirements and integration features. All the chapters are written by experts and researchers working in various areas of the biomedical and healthcare domain and they also dive into one of the most overlooked methodological, practical, and moral questions to secure and handle the enormous amount of data being generated from IoT-enabled biomedical and healthcare systems. In the beginning, this book presents an overview and then discusses open issues, challenges, and applicability aspect of Blockchain technology in healthcare. Then, this book presents a variety of perspectives on the most pressing questions in the field, for example: how IoT can connect billions of biomedical and healthcare information; how the blockchain-based secure access control mechanisms in biomedical and healthcare work; how to address the Quality-of-Service (QoS) and real-time accessibility requirements for healthcare applications; and how to ensure communication with efficiency. Also, it discusses Blockchain for IoT-enabled healthcare systems and presents a comparative analysis with respect to various performance evaluation metrics too.

This book describes the basic concepts and recent advances in new discoveries and technologies related to microbial omics and their role in environmental research and human health. The term'omics'refers to a blend of high-throughput analysis and traditional methods including genomics, transcriptomics, proteomics, lipidomics and metabolomics for a variety of applications in the field of life sciences, biomedical sciences, environmental sciences, and related industries. The book aims to fill the existing gap in terms of a comprehensive approach that incorporates recent advances in this dynamic field and provides an answer to why this field requires an interdisciplinary research approach. The focus of this book is on the applications of genomics, epigenomics, metagenomics, integrative omics, machine learning and microbiome research in environmental health, disease, wastewater epidemiology, antibiotic resistance, drug discovery, cancer, production of secondary metabolites of microbial origin, oxidative stress alleviating mechanisms, etc. The overall construction of this book emphasizes three major perspectives, namely, elaborate knowledge from fundamentals to recent advances in technologies about omics in general and its application in microbiology, environment, and health in particular; illustrative figures capable of easy visualization of complex pathways; and serving as a platform for highly demanded bioinformatics strategies including relevant codes, programming scripts, machine learning and use of artificial intelligence strategies needed to streamline the research outcomes. With global contributions from authors from internationally renowned organizations who excel in relevant research, this book will benefit bibliophiles and prospective audiences from the research fraternity, academia, professionals, and experts in the field of life sciences, biomedical as well as industries related to the development of drug design and novel advances in biotechnological applications.