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Kaihua paper is a type of precious hand-made paper in China that has been used throughout Chinese history. Due to its extraordinary whiteness and fine texture, it was adopted by the imperial palace in the reign of Emperor Kang Xi and Yong Zheng of the Qing Dynasty of China in the 17th and 18th century. It is stained by a special type of yellowish-brown spot after years of storage, which is called a "peachy spot." The formation of such spots remains unclear, although complicated physicochemical processes or microbial activities might be involved. We performed nondestructive sampling and high-throughput sequencing on peachy spot surfaces, unstained areas, and air samples in the stack room to analysis the the bacterial and fungal communities, and performed prediction of functional genes of the bacterial communities. The results showed that peachy spot formation was mainly related to bacterial communities rather than fungal communities. Significantly more potential acid-producing, acidophilic or cellulase-producing bacteria, such as, Streptococcus, Staphylococcus, and Lysinibacillus, and pigment-producing bacteria, such as Methylobacterium and Rubrobacter, were identified in the peachy spot samples. Prediction of the functional genes of the bacterial community also suggested the production of acidic substance pigments. These findings provide new insights into the pigment formation mechanism in ancient paper and open an opportunity to develop new strategies to preserve the ancient paper documents. [ABSTRACT FROM AUTHOR]

In the late Qing Dynasty, religious periodicals by Western missionaries were made legal in China, and subsequently became an important manner of their missionary cause. Among them, Child's Paper 小孩月报 (1875–1881) by John Marshall Willoughby Farnham, a Protestant missionary from the United States, endeavoured to convert child readers by carrying children's stories of moral and emotional education. By concentrating on the educational elements of Child's Paper, this article inspects how conversion was achieved via the intertextual interpretation of Christian doctrines within these educational elements. Specifically, how the image of little Christians and urchins, respectively, represents salvation and redemption in Christian morals. This article holds that the missionaries' stress on the authority of Christian discourse in the education of Chinese children makes evident an increasing emphasis on the reformative effects of Christianity on Chinese children. Moreover, the conversion-education efforts by missionaries also construed helping Chinese children gain a cross-cultural perspective on Western religion, and arguably inspired later Chinese intellectuals' to create newspapers for the purpose of the pre-primary education of Chinese children. [ABSTRACT FROM AUTHOR]

Background: The advent of Personalized Medicine (PM) holds significant promise in revolutionizing healthcare by tailoring treatments to individual patients based on their data. However, its successful implementation requires the seamless integration of innovative technologies and presents formidable challenges in terms of sustainability. To tackle these challenges head-on, the International Consortium for Personalized Medicine (ICPerMed) was established, and the IC2PerMed project, as part of this consortium, seeks to foster collaboration between the European Union (EU) and China in the field of Personalized Medicine. Based on the results collected by the project, the objective of this study is to discern the key priorities for the implementation of Personalised Medicine concerning Information and Communication Technologies (ICT) and Big Data and digital solutions, with a particular emphasis on data management and protection. Methods: A Delphi survey was conducted to gather expert's consensus on the main priorities for actions on Information and Communication Technologies (ICT) and Big Data and digital solutions in the field of Personalized Medicine. Results: The survey identified seven priorities in the area of Big Data and digital solutions, including data interoperability, standards, security measures, and international partnerships. Additionally, twelve priorities were identified for the innovation-to-market process, emphasizing cost-effectiveness, need assessment, and value definition in resource allocation. Conclusions: The effective implementation of new technologies in Personalized Medicine research and practice is essential for the advancement of healthcare systems in both the European and Chinese contexts. The identified priorities play a pivotal role in promoting the sustainability of health systems and driving innovation in the implementation of Personalized Medicine. Addressing challenges related to data interoperability, standards, security, international collaboration, cost-effectiveness, and value assessment is of utmost importance in order to propel the progress of Personalized Medicine in healthcare systems. [ABSTRACT FROM AUTHOR]

Introduction: Over the last decade, the emergence and spread of personalized medicine (PM) have defined a substantial revolution in healthcare. In principle, healthcare system sustainability is challenged by the investments required for research and development, as well as the adoption of PM techniques in routine clinical care. The "Integrating China in the International Consortium for Personalized Medicine" (IC2PerMed) EU-funded project aims to integrate China into the "International Consortium for Personalized Medicine" (ICPerMed). IC2PerMed aims to align the EU and China's research agendas in this field to enable a swift development of approaches in the EU and China with strong leverage upon EU-Chinese collaborations. Methods: Within this project, we first mapped relevant policies on PM in both the EU and China, and then we involved European and Chinese experts in PM in workshops and Delphi surveys in order to identify relevant priorities for the implementation of PM in sustainable healthcare. Results: As a result of this process, we identified nine overarching priorities, each addressing specific aspects of the sustainability of healthcare systems and PM implementation, with the main goal of supporting policymakers in integrating PM approaches in the EU and China. Discussion/conclusion: The implementation of PM in health systems is appealing in terms of improved accuracy in diagnostics, treatment, and prevention of disease, as well as reduction of the side effects resulting from inefficient use of drugs. Research, development, and implementation of needed techniques require time and resources that can slow the adoption of PM in healthcare systems. The nine priorities we identified address some of the most critical points, trying to lay the foundations for a comprehensive approach. [ABSTRACT FROM AUTHOR]

[Display omitted] • 28 out of 57 target PFAS were detected in paper products from China. • 9 groups of PFAS with 1–3 confidence levels were identified by non-target analysis. • Ethanol in food simulants can increase the migration of PFAS. • Long-chain PFAS in popcorn bags can be degraded by microwave heating. • PFAS in some paper products exceeded the recommended daily intake values. The contamination characteristics, migration patterns and health risks of per- and polyfluoroalkyl substances (PFAS) were investigated in 66 Chinese paper products by using target and non-target screening methods. Among 57 target PFASs, 5 and 6 PFASs were found in the hygiene paper products (

Machine learning (ML) has become increasingly popular in the prediction of debris flow occurrence, but the various ML models utilized as baseline predictors reported in previous studies are typically limited to individual case bases. A comprehensive and systematic evaluation of existing empirical evidence on the utilization of ML as baseline predictors for debris flow occurrence is lacking. To address this gap, we conducted a meta-analysis of ML-based prediction modeling of debris flow occurrence by retrieving papers that were published between 2000 and 2023 from the Scopus and Web of Science databases. The general findings were as follows: (1) A total of 84 papers, distributed across 37 different journals in this time period, reflecting an overall upward trend. (2) Debris flow disasters occur throughout the world, and a total of 13 countries carried out research on the prediction of debris flow occurrence based on ML; China made significant contributions, but more research efforts in African countries should be considered. (3) A total of 36 categories of ML models were utilized as baseline predictors for debris flow occurrence, with logistic regression (LR) and random forest (RF) emerging as the most popular choices. (4) Feature engineering and model comparison were the most commonly utilized strategies in predicting debris flow occurrence based on ML (53 and 46 papers, respectively). (5) Interpretation methods were rarely utilized in predicting debris flow occurrence based on ML, with only 16 papers reporting their utilization. (6) In the prediction of debris flow occurrence based on ML, interpretation methods were rarely utilized, searching by data materials was the most important sample data source, the topographic factors were the most commonly utilized category of candidate variables, and the area under the ROC curve (AUROC) was the most frequently reported evaluation metric. (7) LR's prediction performance for debris flow occurrence was inferior to that of RF, BPNN, and SVM; SVM was comparable to RF, and all superior to BPNN. (8) The application process for the prediction of debris flow occurrence based on ML consisted of three main steps: data preparation, model construction and evaluation, and prediction outcomes. The research gaps in predicting debris flow occurrence based on ML include utilizing new ML techniques and enhancing the interpretability of ML. Consequently, this study contributes both to academic ML research and to practical applications in the prediction of debris flow occurrence. [ABSTRACT FROM AUTHOR]

Accompanying China's accession to the World Trade Organization, the rapid development of the Chinese economy has led to increasingly serious environmental issues. However, the inherent mechanisms underlying the impact of Environmental Information Disclosure (EID) policy and trade on the environmental effects of Chinese paper enterprises remain unclear in the context of the era's requirement for a resource-conserving and environmentally-friendly society. The pollution problem in the papermaking industry has received attention worldwide, and how to balance the environmental and development issues of papermaking enterprises is an urgent issue that needs to be solved in the academic community. This study explores the impact mechanisms of EID policy and trade on the environmental effects of enterprises from the perspective of financial constraints. Utilizing the PSM-DID model, the study investigates the moderating effects of financial constraints on the EID policy and import-export trade. The findings reveal that both external and internal financial constraints have negative, detrimental effects on the environmental effects of the EID policy and trade. These constraints impede research and development investment and technological upgrades, hinder productivity improvement, and hamper the realization of "regulatory and trade innovation effects". This study enriches our understanding of the mechanisms by which trade affects the environmental effects of Chinese paper enterprises and further identifies the impacts of Chinese EID policy and trade on pollution emissions by enterprises, providing a theoretical basis and practical foundation for the government in formulating financial, environmental, and trade policies. • Analyzing the environmental effects of Chinese paper enterprises from the perspective of financing constraints. • This study validated the research hypothesis using three micro databases. • This study decomposes the impact mechanism into three aspects: scale effects, technical effects, and structural effects. [ABSTRACT FROM AUTHOR]

The exponential growth of China's economy, coupled with the surge in online commerce, has led to a significant expansion of the logistics industry. In 2022, China's express delivery industry generated approximately 9 million tons of waste paper and 1.8 million tons of plastic. This study analyzed the current composition and utilization of logistics waste in China, with suggestions for recycling. Logistics waste can be defined as the packaging waste generated in the logistics industry. Corrugated paper and plastic waste were chosen as the objects for utilization. Due to its high cellulose content, corrugated paper can be utilized along with other paper waste for biomass resourcing. Biodegradable plastics can also be converted into biomass resources through the action of specific microorganisms. These polymers can be enzymatically depolymerized by certain bacteria and fungi, yielding valuable organic products. In general, logistics wastes all have potential for biomass resource recovery. By adopting appropriate recovery and conversion technologies, these waste streams can be transformed into high-value bio-based products, such as biofuels, biochemicals, and biopolymers, thus contributing to the development of a circular and sustainable economy. [ABSTRACT FROM AUTHOR]

Green bonds are relatively new in the financial market compared to other financial securities but are useful in financing environmentally friendly projects. Just like other financial securities, green bonds are affected by various factors, such as economic policy uncertainty. Our aim of this paper was to conduct a systematic literature review of the impact of economic policy uncertainty on green bonds. We sought to do a thorough analysis of the existing literature on the assessment of the impact of economic policy uncertainty on green bonds and the techniques used in assessing the impact. Our findings showed that economic policy uncertainty had a strong impact on the green bond, with its intensity varying by location. This impact tended to be more pronounced in periods of heightened uncertainty. Also, our findings highlighted that the assessment of the impact of economic policy uncertainty on green bonds gained popularity in 2019, with China emerging as a prominent contributor. However, other countries, such as Finland, even though they had few published papers, their citations signified the production of quality papers in this field. Additionally, we found that the application of the quantile analysis method was utilized by many recent studies, which signified its importance in this field. Our findings highlighted the importance of considering appropriate techniques in assessing the impact of economic policy uncertainty on green bonds while taking into account the paper quality. [ABSTRACT FROM AUTHOR]