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A comparative study was conducted in a printing plant regarding various methods of measuring environmental concentrations of a solvent vapour mixture, the major components of which were n-hexane, ethyl acetate and toluene. Introduction of a portable gas-liquid chromatograph made it possible to analyze spot-air samples at the site of the exposure, and thereby obtain immediate information on its quality and quantity. The results were compared with those from personal sampling and continuous stationary sampling coupled with gas-liquid chromatographic analysis well as detection tube methods. Spot-air, personal and continuous stationary sampling methods were in good parallel while the detection tube method was less valid in the case of vapour mixture exposure. Studies on toluene metabolism revealed that the biological half-life of toluene was about 7.5 hrs and that the metabolism was not significantly disrupted by the co-presence of other solvents such as ethyl acetate and n-hexane. [ABSTRACT FROM AUTHOR]

A glue sniffer manifested marked muscular atrophy in the four extremities while sensory functions remained more or less intact. Glue analysis revealed n-hexane, toluene, and ethyl acetate as leading solvents. Rat experiments revealed that metabolism of n-hexane was not modified by co-administered toluene and vice versa, indicating that the atypical symptom in the present case was not due to metabolic modification between n-hexane and toluene. [ABSTRACT FROM AUTHOR]

Mechanisms of respiratory retention of organic solvents are discussed. Respiratory retention, uptake and excretion were estimated separately in 66 men and women volunteer students exposed to benzene, toluene, n-hexane, trichloroethylene, acetone, ethyl acetate and ethyl alcohol. After 2 hrs exposure, respiratory retention reached constant levels; these differed for each of the 7 organic solvents tested. No sex difference in retention was observed. Respiratory excretion values differed as 100 × concentration in expired air immediately following breathing of solvent free air/concentration of solvent in air breathed during exposure. Men excreted more toluene and trichloroethylene than did women. Uptake varied 27-60%. [ABSTRACT FROM AUTHOR]

Respiratory elimination of benzene, toluene, n-hexane, trichloroethylene, acetone, ethyl acetate and ethyl alcohol were studied after exposure in human volunteers to those solvents. [ABSTRACT FROM AUTHOR]

A description is given of apparatus employing a cell that is both a bellows dilatometer and a three-terminal electrode set for measuring simultaneously the density and dielectric properties of liquids as functions of temperature and pressure. Measurements are possible at temperatures from 120 °K to over 300 °K and pressures from 1 to 2000 atm with an uncertainty of 0.03 percent. The density, dielectric constant, and Clausius-Mossotti function of n -hexane have been measured for temperatures from 223 to 298 °K (-50 to 25 °C) and at pressures from 1 to 2000 atm. There is a linear decrease in the Clausius-Mossotti function with density and a decrease with temperature corresponding to an effective dipole moment of 0.085 debye.