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The evaluation of the results of CVP and MOPP chemotherapy in 80 patients with advanced stages of non-Hodgkin’s lymphoma indicates that 36 (45%) achieved a complete remission. Twenty-eight per cent of the entire group of patients remain free of disease for periods ranging from 4 mo to over 7 yr, with a projected median duration of complete remission of 3½ yr. Significant differences in prognosis relative to histologic categories were found. Well-differentiated and nodular histology were positive determinants for improved median survival, confirming the over-all clinical validity of the Rappaport classification system for the non-Hodgkin’s lymphomas. The median survival for patients in the most clinically aggressive subgroups with diffuse histology is inferior to those with nodular patterns or well-differentiated cells. In this study it was demonstrated that it was possible to achieve a significant number of complete remissions even in the most aggressive histologic subgroups using combination chemotherapy, and these responses can be correlated with an extended disease-free survival without further therapy.

1. The experience with carcinoma of the endometrium at the Radiotherapy Department of the I. Gonzalez Martinez Oncologic Hospital is presented. A total of 105 patients were seen from January 1, 1956 to December 31, 1966.2. All patients were submitted to irradiation followed by surgery for operable cases.3. The preferred form of preoperative irradiation was a combination of external irradiation and intracavitary curietherapy. This achieved tumor disappearance from the operative specimen in over 50 per cent of the cases.4. The 3 and 5 year survival results have been analyzed and correlated with the stage of the disease and the treatment modalities employed.5. A net 5 year survival of 69 per cent was obtained in 49 patients of all stages, who qualified for 5 year evaluation.6. An analysis of the published international results of treatment of carcinoma of the endometrium gives basis to the conclusion that preoperative irradiation affords the best chance of 5 year disease free survival for all patients with t...