1. Comparative clinical trial of diazepam with other conventional drugs in tetanus.
- Author
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Vassa, Nalini T., Yajnik, V. H., Joshi, K. R., Doshi, H. V., Shah, S. S., Patel, S. H., and Vassa, N T
- Subjects
COMBINATION drug therapy ,CLINICAL trials ,COMPARATIVE studies ,CLINICAL drug trials ,DIAZEPAM ,NEONATAL diseases ,RESEARCH methodology ,MEDICAL cooperation ,RESEARCH ,SPASMS ,TETANUS ,EVALUATION research ,RANDOMIZED controlled trials ,PHARMACODYNAMICS ,THERAPEUTICS - Abstract
Results of therapeutic trial of diazepam in tetanus are presented. The trial included 200 cases of tetanus—167 non-neonates and thirty-three neonates. The patients were divided into two groups and were matched as regards age, sex and severity of the disease. The cases of group I received standard treatment while the cases of group II received diazepam in addition. Over-all mortality in group I was 54% and in group II, 26%. The results were statistically significant in non-neonates and in severe degree of tetanus. The drug was well tolerated and side effects were not observed. [ABSTRACT FROM PUBLISHER]
- Published
- 1974