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The application of ultrasonic diagnosis in the care of patients suffering from tumors of the urogenital tract is discussed. The indication for demonstration of enlarged paraortic and lumbar lymphnodes is emphasized. Of special value is this new diagnostic tool for X-ray treatment planning and for the evaluation of the therapeutic success.

The responses to several skin test antigens of patients with bladder or prostatic cancer has been compared with responses of normal controls. All of the controls and all of the patients with prostatic cancer (irrespective of the stage of the tumour or the method of treatment) showed responses to dinitrochlorbenzene. 80% of all patients with bladder cancer responded to DNCB, but a highly significant number of patients with advanced disease showed no response. This test appears especially useful in predicting the prognosis in patients with bladder tumours and its routine use is recommended. Response to candida extract, streptokinase/streptodornase (SKSD) and purified protein derivative (PPD) were also studied. No conclusion could be drawn as to their value as a prognostic index.

Images Figs. 9-11 Figs. 1-2 Figs. 3-4 Figs. 5-6 Figs. 7-8

Bei 30 Patienten mit Karzinomen unterschiedlicher Lokalisation und Ausbreitungs-stadien wurden die Lymphozyten des peripheren Blutes mit Hilfe der Nukleolenfarbung nachStockinger undKellner differenziert.

Es wird eine Ubersicht uber eine Geschwulstart gegeben, die Bodian das embyonale Sarkom nannte und die in der Literatur auch unter der Bezeichnung (embryonales) Rhabdomyosarkom und Sarcoma botryoides beschrieben wird. Acht eigene Beobachtungen dieses Tumors in einem Zeitraum von 14 Jahren werden angefuhrt. Bei 5 unserer Patienten war das e. S. im Kopfbereich, bei einem im Gallenwegsbereich und bei 2 im Bereich des Sinus urogenitalis lokalisiert. Die therapeutischen Ergebnisse erscheinen nicht ganz so ungunstig, wie meist in der Literatur angegeben.

1. A study of 215 cases of metastatic pulmonary carcinoma revealed 34 (15.8 per cent) instances in which the histologic features were compatible with the diagnosis of primary bronchiolo-alveolar carcinoma. 2. The metastatic bronchiolo-alveolar tumors were found chiefly in cases of carcinoma of the pancreas, colon, breast, stomach, and kidney, respectively. 3. Bronchiolo-alveolar carcinoma is not a specific entity, but a histologic pattern of malignant epithelial proliferation occurring both in primary and metastatic lung cancer. 4. The distinctive glandular appearance is dependent on the anatomic structure of the lung parenchyma which provides an alveolar stroma along which the malignant cells can propagate. The histologic differentiation between primary and metastatic bronchiolo-alveolar carcinoma presents a diagnostic challenge in the absence of necropsy.

A series of 36 patients having cutaneous metastases, including 32 necropsied cases in necropsy series of approximately 2,300 cases of internal carcinoma derived from the Long Beach Veterans Administration Hospital. The lung was the primary site in 17 of the 36 cases, the gastro-intestinal tract in 8 and the genito-urinary tract in 10; the primary site of one was uncertain. The tumors of the lung most commonly metastasized to the skin of the chest and those of the gastro-intestinal tract and genitourinary tract to the abdominal wall. The skin metastases were multiple except for 4 cases, usually widespread in location and occasionally appeared in small crops. The tumors were most commonly solid painless elevated nodules, ranging from one to 3 cm in diameter, having an intact overlying epidermis. The microscopic appearance had features of adenocarcinoma in 26 of the 36 cases. The skin tumors were indicative of progression of the primary tumor and early fatal termination, the duration of life averaging about 3 months after the appearance of the skin tumors. The necropsies revealed widespread metastases.

Benign tumours of the epididymis, which are very rare, are variously regarded as adenomas, mesotheliomas and lymphangiomas, but an alternative opinion considers them to be of Mullerian vestigial origin. Their malignant counterparts are extremely rare, and this case is probably the second authentic instance to be reported in the English literature. Complete excision of the mass with wide resection of the cord followed by prophylactic local deep X-ray therapy has provided total relief to the patient over the year which has elapsed since these measures were undertaken.

Summary A case is described of a large cyst arising in a male pelvis from the vicinity of the prostate and seminal vesicles, and it is considered that the most likely origin of this cyst is from remnants of the Miillerian duct. The literature of this condition is briefly reviewed.