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The changes in serum IgE levels of the patients with allergic nasal diseases were examined by the radioimmunosorbent test (RIST) and their diagnostic values were discussed as follows: 1) The patients with allergic nasal diseases showed higher serum IgE levels than non-allergic patients. 2) The serum IgE level of the patients with asthma and/or atopic dermatitis with nasal allergy complications was about 3 times higher than that of patients without such complications. 3) Serum IgE concentration of the pollinosis patients increased significantly in the pollinating season. 4) Serum IgE level of the patients allergic to house dust is higher than that of normal individuals, and is roughly parallel to the blood eosinophil count. 5) The patients with allergic rhinitis show increased IgE values as the degrees of positive HD skin tests get higher. 6) By specific desensitization therapy using serum IgE levels increased during the early stage of this treatment but no decrease was seen as the therapy progressed.

Arginineの負荷は成長ホルモン分泌を促進することから, 血中の成長ホルモン測定用診断薬として用いられている。このarginineの生体内運命を明らかにするため, 14C-arginineを500mg/kg体重の割合でマウスに静脈注射し, 凍結全身オートラジオグラフィによる生体内分布を検討した。静注後60分の放射能濃度は腎臓, 膵臓, 消化管壁, 骨格筋, 唾液腺などに高くみられ, 皮ふ, 睾丸, 副腎, 脳下垂体には中程度の活性が観察された。しかし肝臓, 肺臓, 血液, 脳および褐色脂肪組織への取込みは少なかった。投与後6時間には皮ふ, 消化管壁, 胸腺皮質などにまだかなりの放射能が認められたが, 骨格筋の活性は顕著に減少した。マウス組織をTCAでhomogenizeし, TCA抽出画分およびTCA不溶タンパク画分の放射能取込み量を求めたところ, 投与後初期にはTCA画分がタンパク画分に比して高く, とくに膵臓と腸管壁が著明に高かった。投与後24時間のTCA画分は各組織とも著しく減少したが, 脳および筋肉のタンパク画分への取込み量は増加した。一方, 各組織中に取り込まれた全放射能に対する14C-arginineの割合を求めたところ, 投与後30分では筋肉中に約30%, これに対して肝臓はきわめて低く3%であった。肝中代謝物の大部分は14C-ureaであった。14C-arginineを投与後24時間までの尿中に, 投与した放射能の74%が排泄された。尿中放射能の約75%は14C-ureaであり, 未変化の14C-arginineは約9%であった。呼気の累積14CO2は24時間まで投与放射能の8.3%であった。

New index (F) was proposed in order to express the frothing characteristics of surfaceactive agents.F=Vf/V2Where, Vf is the froth volume discharged per unit time (cm3/min), and V2 is the flow rate of the gas sended to form froth (cm3/min).Using this index F, the frothing characteristics of sodium oleate (Na-ol.) solutions were determined. Then the effect of MIBC (4-methyl 2-pentanol) and of the height of froth layer on the frothing characteristics of Na-ol. solutions were investigated.The results were as follows.1) The frothing characteristics of Na-ol. solutions (F) decreased rapidly under the concentration of 0.2 g/l of Na-ol.2) When small quantities of MIBC were added to 0. 2 g/l Na-ol. solution, the value of F increased, although it decreased rapidly over the concentration of 10 ml/l of MIBC.3) The heigher the froth layer, the smaller the value of F.4) Addition of small quantities (under 5 ml/l) of MIBC to 0.5g/l Na-ol. solution, didn't decrease its frothing characteristics though the froth layer became heigher.

There have been synthesized dl-10-desoxy-18, 19-dihydro-15-epi-hunterburnine according to the oxidative cyclization reaction with mercuric acetate, and its structure was determined by nuclear magnetic resonance (NMR) and mass-spectra.

Infrared Spectra of a number of indole compounds have been examined and the characteristic frequencies of indole group are given. The CH out-of plane bending vibration of the pyrrole moiety of the indole ring and related methylpyrroles are discussed.

A new method for recovering heavy metals in waste water was proposed. The reforming agent was used in this method, which combined with heavy metals to render them soluble and foamy. Air was then blown into the solution, and heavy metals, combined with reforming agent, were readily recovered on terms of a foamy shape during 10-20 minutes. This new method might solve many difficult problems involved in the conventional methods of treating waste water containing heavy metals.