1. The role of cyclic AMP in slime mold development
- Author
-
James F. Grutsch and Anthony Robertson
- Subjects
biology ,Chemistry ,fungi ,macromolecular substances ,General Medicine ,biology.organism_classification ,Models, Biological ,General Biochemistry, Genetics and Molecular Biology ,Dictyostelium discoideum ,Cyclic AMP receptors ,Biochemistry ,Good evidence ,Cyclic AMP ,Slime mold ,Dictyostelium ,General Pharmacology, Toxicology and Pharmaceutics ,Cyclic AMP metabolism ,Signal Transduction - Abstract
Summary Cyclic AMP acts as an aggregative attractant in Dictyostelium discoideum and possibly in other cellular slime molds. There is good evidence that extra-cellular cyclic AMP is also involved in the control of morphogenetic movement and of differentiation throughout the D. discoideum life cycle. In this paper we review what is known of the cyclic AMP signal, of the responses to it and of cyclic AMP metabolism in D. discoideum.
- Published
- 1974