1. Further studies of the electrocardiographic effects of experimental myocardial lesions
- Author
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J.A. Abildskov and Robert S. Boyle
- Subjects
medicine.medical_specialty ,Heart Diseases ,Myocardial Infarction ,Electrocardiography ,QRS complex ,Basal (phylogenetics) ,Dogs ,Internal medicine ,medicine ,Animals ,Humans ,cardiovascular diseases ,Interventricular septum ,Myocardial infarction ,medicine.diagnostic_test ,business.industry ,Research ,Right ventricular infarction ,Anatomy ,medicine.disease ,medicine.anatomical_structure ,Ventricle ,cardiovascular system ,Right lateral wall ,Cardiology ,Cardiology and Cardiovascular Medicine ,business ,circulatory and respiratory physiology - Abstract
The electrocardiographic effects of 25 chemically produced myocardial lesions in dogs were studied. Eleven of these were restricted to the subepicardial half of the left ventricular wall, 2 were located in the posterior basal portion of the left ventricle, and 12 were located in the right ventricular wall. Eight of the 11 subepicardial left ventricular lesions altered only mid-temporal and terminal portions of the QRS complex. The other 3 lesions were all located near the interventricular septum and altered early as well as later portions of the QRS. The 2 lesions of the posterior basal left ventricular wall altered only mid-temporal and terminal portions of the QRS complex. Right ventricular lesions in the right lateral wall near the base and those near the interventricular septum altered early as well as late portions of the QRS complex. Other right ventricular lesions altered only mid-temporal and terminal portions of the QRS. The significance of these findings may be summarized as follows: (1) Lesions in a variety of locations cannot be recognized by electrocardiographic standards which require abnormalities of the initial portion of the QRS complex. (2) Recognition of the relatively small and variable electrocardiographic effects of subepicardial, posterior basal, and right ventricular lesions may require modification of current clinical electrocardiographic techniques and standards for the diagnosis of myocardial infarction (3) The finding that most subepicardial lesions did not alter initial portions of the QRS is not consistent with reported evidence that activation of only subepicardial portions of the heart contributes to the form of QRS deflections.
- Published
- 1965