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An ultrastructural study of 2 cases of lymphomatoid papulosis (Macaulay) showed the prevalence of lymphocytes in the dermal infiltrate, with a variable admixture of other inflammatory cells. These lymphocytes are normal or in lymphoblastic transformation; some are abnormal in size (up to 12 µm in diameter) and have corrugated or cerebriform nuclei like “small” Sezary cells. Histiocytes have an indented nucleus, an actively phagocytic cytoplasm and sometimes vermiforme inclusions 150–180 A wide. Circulating and dermal polymorphonuclear leukocytes are rich in caryoschisis. In short, the ultrastructural pattern is inflammatory and also close to lymphomas.

An ultrastructural study of the dermis in a case of acrogeria is presented and compared with a healthy control of same age and sex. The overgrowing orceinophil material was mainly pseudoelastic. The collagen was hypoplastic and mostly immature. Inside and outside the fibroblasts a lot of a granulofilamentous substance intermingled with pseudoelastin and immature collagen was observed. Fibroblast cytoplasm was often distended by ergastoplasmic vacuoles filled with granulo filamentous substance and contained numerous pseudomyelinic bodies. These abnormalities suggest that acrogeria might be a fibroblast disease.

From international conference on ion-surface interaction, sputtering, and related phenomena; Garching, Germany (Sep 1972). The secondary ion emission of solid and liquid aluminum versus temperature from 300 to 1000 deg K was studied with a Slodzian' s microanalyser in which the target is horizontal. An increase with temperature of the secondary emission was found in channeling directions and a decrease in the other directions. The behavior of the clusters was also studied. No great difference was found between solid and liquid state for the clusters intensities. A slight difference is found in the energy distribution of secondary ions when the crystal is bombarded in different directions. (auth)

Samples of human Stratum corneum (St. c.) collected by the cantharidin method and suspended in a controlled atmosphere usually show a raised extensibility when the relative humidity (RH) is raised, and, consequently, a greater solidity. When the St. c. samples were not suspended but laid on a wet pad, extensibility did not change when RH was raised, but elongation decreased owing to a strong reduction of breaking strength; the St. c. became more fragile. Electron and optical microscopic studies revealed that this latter phenomenon was due to an alteration of the links between cells, i. e. cell interlockings, desmosomes, intercellular cement. In this experiment, St. c. samples were not stiff as when suspended in air, but supple as in vivo; the technics provide a good model for in vivo hyperhydrated St. c.