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The compounds present in urine pools from schizophrenic and normal male individuals and which give colors with diazotized sulphanilic acid, and which can be extracted with ethyl acetate or eluted with aqueous phenol from charcoal adsorbates, have been compared and a number identified. Of the over 80 compounds detected only three, which do not contribute markedly to the over-all coloring pattern, have appeared uniquely in the three urine preparations from schizophrenics. Urocanic, 2-acetamidobenzoic, and imidazole-4-acetic acid have been chromatographically detected in human urine.

The oral administration of vitamin E to human subjects in dail doses of 600 mgm. for seven days failed to evoke any blood change in clotting times, prothrombin times, or plasma fibrinogen levels. There was a small increase in platelet level which was statistically of borderline significance.