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For diagnostic purposes in allergic diseases a positive reaction to skin testing is not significative of a clinically manifest hypersensitivity to the offending allergen (Salen and Juhlin-Dannfeldt...

UP TO 1890 the correction of septal deviations was accomplished by orthopedic redressment—a procedure which contemplates fracturing the septum and maintaining it in the sagittal plane over a period of months by the use of intranasal tubes. The method was successful in the correction of deflections of the bony septum, the friability of osseous structure permitting easy fracture and maintenance in the new position. It was ineffective, however, when the cartilage was involved, for cartilage, because of its great elasticity, is not easily fractured, and the tendency to return to its original form and position remained, despite attempts to overcome this difficulty by cross hatching or removing redundant strips, with or without elevation of the overlying membrane. Further objections were the damage inflicted by the crushing force of the instruments on the membrane, the discomfort of the prolonged postoperative treatment, and the tendency toward atrophy and necrosis of the membranes

Common causes of nasal obstruction are discussed. Among them are acute and chronic rhinitis, congenital or acquired nasal anomalies, septal hematoma and abscess, foreign bodies, and benign and malignant tumors of the nose and nasopharynx.

Intranasal injections into the inferior turbinates of a slightly form of prednisolone TBA (Hydeltra(R) TBA) into persons with complaint of nasal obstruction gave considerable relief in 78 per cent of cases. Nasal hyperfunction due to seasonal allergic rhinitis, vasomotor rhinitis and secondary nasal edema from sinusitis was the indication for use. No local or general reactions other than a small amount of bleeding at the time of injection was noted. This method allows full utilization of the anti-inflammatory activity of corticosteroids at the local tissue level without producing a systemic effect.