1. Heart remodelling type role and effectiveness of lisinopril and bisoprolol therapy among patients with rheumatic mitral disease
- Author
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T. A. Abdullaev, Kh. K. Mukhiddinov, N. A. Kurbanov, and B. U. Mardanov
- Subjects
rheumatic valve pathology ,mitral insufficiency ,RC666-701 ,lisinopril ,bisoprolol ,cardiovascular system ,Diseases of the circulatory (Cardiovascular) system ,cardiovascular diseases ,mitral stenosis - Abstract
Aim. To study the association between heart remodelling types and cardiac arrhythmias; to assess the effectiveness of lisinopril and bisoprolol therapy in patients with rheumatic mitral disease (RMD).Material and methods. In total, 48 patients (mean age 49,5±3,8 years) with RMD were divided into two groups: Group I (n=28) with predominant mitral stenosis (MS) and Group II (n=20) with predominant mitral insufficiency (MI). The examination included electrocardiogram (ECG), 24-hour ECG monitoring, heart X-ray with cardiothoracic index calculation, echocardiography, and plasma C-reactive protein level measurement. The follow-up period lasted for 6 months.Results. In both groups, clinical and hemodynamic parameters had improved, including left ventricular (LV) diastolic function improvement. Conservative therapy was more effective in individuals with lower LV ejection fraction (EF) values, mitral ostium area >1,5 cm2, and left atrium size
- Published
- 1970