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Your search keyword '"McRae, K"' showing total 40 results
Start Over Author "McRae, K" Publication Year Range More than 50 years ago
40 results on '"McRae, K"'

8. Comparison of strip and Ziehl—Neelsen methods for staining acid-fast bacteria*

Author

Varughese, P., Helbecque, D. M., McRae, K. B., and Eidus, L.

Subjects
Analysis of Variance, Bacteriological Techniques, fluids and secretions, Staining and Labeling, parasitic diseases, Rosaniline Dyes, Sputum, Humans, Cell Count, Articles, Mycobacterium tuberculosis, bacterial infections and mycoses, Coloring Agents
Abstract

The efficiency of the Ziehl-Neelsen method for staining acid-fast bacteria was compared with that of the strip-staining procedure in which one kind of impregnated strip is used to stain the bacteria and another kind for simultaneous decolorization and counter-staining of the smear. The methods were evaluated in 1 136 duplicate smears prepared from digested sputum and 307 pairs of direct smears. The efficiency of the strip method was comparable to that of the Ziehl-Neelsen method with digested sputum; with direct smears, however, it generally depended on the quality of the smear. With thick, uneven smears, lower bacterial counts were obtained by strip staining. On the basis of this trial, the authors suggest improvement of the strip method.

Published
1974

9. Simplification of isoniazid phenotyping procedure to promote its application in the chemotherapy of tuberculosis*

Author

Eidus, L., Varughese, P., Hodgkin, M. M., Hsu, A. H. E., and McRae, K. B.

Subjects
Phenotype, Pharmacogenetics, fungi, Isoniazid, Methods, Humans, Tuberculosis, Articles, Acetates
Abstract

In this investigation a simple urine test for phenotyping isoniazid inactivators is evaluated. In the new method, isoniazid is artificially acetylated in urine and determined by the same colour reaction as that used for acetylisoniazid. Comparative studies showed that the test is reliable and can be performed with accuracy and ease even in poorly equipped laboratories. In contrast to other urine tests, it does not require an expensive spectrophotometer, tedious hydrolysis processing of the samples, or standard curves. The results can be read on a plain colorimeter, or even without any instrument.

Published
1973

10. Sex-linked congenital deafness

Author

McRae, K N, Uchida, I A, and Lewis, M

Subjects
Adult, Male, Sex Chromosomes, Intelligence, Age Factors, Genes, Recessive, Manitoba, Deafness, Middle Aged, Audiometry, Child, Preschool, Intellectual Disability, Blood Group Antigens, Humans, Female, Antigens, Child, Research Article
Published
1969

12. Familial occurrence of trisomy 22

Author

Uchida, I A, Ray, M, McRae, K N, and Besant, D F

Subjects
Adult, Chromosome Aberrations, Heart Defects, Congenital, Male, Mosaicism, Infant, Newborn, Infant, Chromosome Disorders, Trisomy, Congenital Abnormalities, Pedigree, Karyotyping, Blood Group Antigens, Chromosomes, Human, 21-22 and Y, Autoradiography, Humans, Female, Dermatoglyphics, Research Article
Published
1968

30. Comparison of strip and Ziehl-Neelsen methods for staining acid-fast bacteria.

Author

Varughese P, Helbecque DM, McRae KB, and Eidus L

Subjects
Analysis of Variance, Cell Count, Coloring Agents, Humans, Rosaniline Dyes, Sputum microbiology, Bacteriological Techniques, Mycobacterium tuberculosis isolation & purification, Staining and Labeling
Abstract

The efficiency of the Ziehl-Neelsen method for staining acid-fast bacteria was compared with that of the strip-staining procedure in which one kind of impregnated strip is used to stain the bacteria and another kind for simultaneous decolorization and counter-staining of the smear. The methods were evaluated in 1 136 duplicate smears prepared from digested sputum and 307 pairs of direct smears. The efficiency of the strip method was comparable to that of the Ziehl-Neelsen method with digested sputum; with direct smears, however, it generally depended on the quality of the smear. With thick, uneven smears, lower bacterial counts were obtained by strip staining. On the basis of this trial, the authors suggest improvement of the strip method.

Published
1974

31. The battered child syndrome.

Author

McRae KN, Ferguson CA, and Lederman RS

Subjects
Age Factors, Birth Weight, Child, Child Welfare, Child, Preschool, Family Characteristics, Female, Follow-Up Studies, Foster Home Care, Humans, Infant, Infant Mortality, Infant, Newborn, Infant, Premature, Intellectual Disability, Male, Manitoba, Parent-Child Relations, Statistics as Topic, Wounds and Injuries epidemiology, Child Abuse
Abstract

The experience of the Children's Hospital of Winnipeg from 1957 to 1971 with abused infants and children is presented with statistical data on 132 children. Details as to incidence, source and types of abuse are presented along with a discussion of the management of the problem. A follow-up study on a group of the abused children is also presented with comments directed towards some preventive measures.

Published
1973

33. Neonatal hypoglycemia: a six-year experience.

Author

Haworth JC and McRae KN

Subjects
Child, Child, Preschool, Female, Humans, Infant, Infant, Newborn, Male, Neurologic Manifestations, Hypoglycemia diagnosis, Hypoglycemia etiology, Infant, Newborn, Diseases etiology
Published
1967

34. Sex-linked congenital deafness.

Author

McRae KN, Uchida IA, and Lewis M

Subjects
Adult, Age Factors, Antigens analysis, Audiometry, Blood Group Antigens, Child, Child, Preschool, Deafness genetics, Female, Humans, Intellectual Disability genetics, Intelligence, Male, Manitoba, Middle Aged, Deafness congenital, Genes, Recessive, Sex Chromosomes
Published
1969

36. Simplification of isoniazid phenotyping procedure to promote its application in the chemotherapy of tuberculosis.

Author

Eidus L, Varughese P, Hodgkin MM, Hsu AH, and McRae KB

Subjects
Acetates urine, Humans, Isoniazid analogs & derivatives, Isoniazid therapeutic use, Methods, Tuberculosis urine, Isoniazid urine, Pharmacogenetics, Phenotype, Tuberculosis drug therapy
Abstract

In this investigation a simple urine test for phenotyping isoniazid inactivators is evaluated. In the new method, isoniazid is artificially acetylated in urine and determined by the same colour reaction as that used for acetylisoniazid. Comparative studies showed that the test is reliable and can be performed with accuracy and ease even in poorly equipped laboratories. In contrast to other urine tests, it does not require an expensive spectrophotometer, tedious hydrolysis processing of the samples, or standard curves. The results can be read on a plain colorimeter, or even without any instrument.

Published
1973

38. Familial occurrence of trisomy 22.

Author

Uchida IA, Ray M, McRae KN, and Besant DF

Subjects
Adult, Autoradiography, Blood Group Antigens, Chromosome Disorders, Congenital Abnormalities etiology, Dermatoglyphics, Female, Heart Defects, Congenital etiology, Humans, Infant, Infant, Newborn, Karyotyping, Male, Mosaicism, Pedigree, Chromosome Aberrations genetics, Chromosomes, Human, 21-22 and Y, Trisomy
Published
1968

39. A problem in child development.

Author

McRae KN

Subjects
Canada, Child, Preschool, Education, Special, Humans, Child Guidance, Learning Disabilities therapy, Psychology, Child
Published
1967

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