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Introduction: Dyslipidemia is a lipid metabolism abnormality marked by increase or decrease of lipid fraction in the plasma. Statin or 3-Hydroxy-3-Methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor is an important dyslipidemia medication that may induce apoptosis of the skeletal muscle.Decrease of Bcl-2 and Bax ratio causing caspase-9 activation followed by caspase-3 activation occur in apoptosis. Moderate intensity physical exercise (MIPE) decreases DNA fragmentation, increases Bcl-2 protein level and decreases Bax transcript level.Methods: Thirty healthy BALB/C strain Mus musculus divided into 3 groups: first intervention group with statin only treatment (S), second intervention group with statin treatment plus MIPE using motorized treadmill (ST), and control (C) group with no statin and nor exercise. The duration of treatmentwas 28 days. Statin treatment dose was 2.06mg/kg bodyweight. Measurement caspase-3 was done by immunohistochemistry evaluation and the expression of capase-3 was calculated by cells count which expressing caspase-3.Results: There were more muscle cells expressing caspase-3 in the S group (47.00±12.92cells) than the C group (2.70±1.94 cells); p=0.000, the ST group (21.44±10.13 cells) than the C group (p=0.001), as well as S group and the ST group (p=0.000).Conclusion: Moderate intensity physical exercise can decrease caspase-3 expression in statin treated subject.Keywords: apoptosis, caspase-3, dyslipidemia, moderate intensity physical exercise, statin.

Copal is originated from the exudate of Agathis loranthifolia tree, which flows out from tapping. copal is one of Indonesia's export comodities. Unfortunately, since the export was still in the form of raw materials, it was necessary to study the identification of resin acid content of the copal of Sukabumi. It was also necessary to test the quality of the copal. Extraction was done by using acetone: MeOH (9:1) solvent. Then the extraction of resin acid content was identified by using Gas Chromatography Mass Spectrometry (CGMS). The quality of copal was evaluated based on SNI 7634-2011. Resin acids of the copal which were identified by CGMS are limonene (44%), ethylene oxide hexamer, cis-limonene oxide, toluene, trans-carveol, 2-siclohexane-1-one, trans-limonene oxide, and alpha pinene. Copal of Sukabumi belong to the first class, because the obtained parameters are not all included in the premier class ranges. However it is still possible to be upgraded to their premier class by removing the dirt.Keywords : Agathis loranthifolia, copal, limonene, resin acids.

This study aims to determine the role of the Central Java Liaison of Judicial Commission in maintaining and upholding the honor, the nobleness of dignity and behavior of judges in Central Java. The research method used in compiling this legal research is descriptive and non-doctrinal research in legal research. This research approach uses a qualitative approach and the object of this research is the Central Java Liaison of the Judicial Commission located in Semarang which was conducted by interviews and observations. Based on the results of research and explanation, the conclusion is that the Liaison of the Central Java Judicial Commission has 3 (three) main tasks and 2 (two) additional tasks. The Liaison of Judicial Commission in maintaining and upholding the honor, the nobleness of dignity and behavior of judges in Central Java is in accordance with Judicial Commission Regulation Number 1 of 2017 concerning Formation, Arrangement, and Procedures of Liaison of Judicial Commissions in the Regions.

This article presents English teacher's challenges in teaching speaking online at one Madrasah Tsanawiyah (MTs) in Palembang, South Sumatera, Indonesia. A qualitative case study was employed in conducting this research. Data were collected by using semi-structured interview with the English teacher through a set of open-ended questions. Thematic analysis was used to identify, analyze, and describe the obtained data in the process of selecting codes and constructing themes. The results revealed that the teacher faced some main challenges in teaching speaking online, as follows: (a) lack of students’ confidence in speaking English, (b) internet connection issues, (c) lack of students’ learning interactions and participations, (d) difficulty in designing/developing speaking materials for online class, (e) difficulty in managing the time, and (f) unreliable online teaching and learning devices. These challenges should be considered and anticipated by the teachers and other pertinent parties to get the alternatives for solutions.

The presence of Annelida animals in water is one indicator of polluted water. The purpose of this research was to determine the diversity of Annelida phylum in the Kapuas and Melawi rivers. This research used an exploratory method to determine the diversity of annelids in the Kapuas and Melawi rivers. Sampling was carried out in 2 regions representing the left and right sides of the river, both upstream and downstream of the river. The findings of the research show that there are two classes of annelid phyla, namely the Oligochaeta and Hirudinae classes. Oligochaeta class is represented by Tubifex sp, Lumbricus terrestris, and Pharetima sp. species while Hirudinae class is represented by Haemodipsa sp. Species. The number of Annelids found in the Kapuas river for Tubifex sp. numbered 7 species, Lumbricus terrestris numbered 53 species and Pharetima sp. numbered 14 species. The number of Annelids found in the Melawi river for Tubifex sp. numbered 1 species, Lumbricus terrestris numbered 23 species, Pharetima sp. numbered 8 species and Haemodipsa sp amounted to 2 species. The presence of Tubifex sp. in the Kapuas and Melawi rivers shows that the quality of the river waters begins to be polluted.

Isolasi Mikroorganisme Anaerob Limbah Cair Tekstil Menggunakan Desikator Sebagai Inkubator Anaerobik. Penggunaan mikroorganisme untuk mengolah limbah cair tekstil yang mengandung bahan organik tinggi sangat potensial untuk dikembangkan. Mikroorganisme anaerob dapat digunakan pada pengolahan limbah cair, yaitu untuk mendegradasi senyawa- senyawa organik kompleks berantai panjang menjadi senyawa yang lebih sederhana sehingga dapat menurunkan beban kerja dari pengolahan aerobik. Penelitian ini bertujuan untuk mengetahui efektivitas desikator termodifikasi sebagai inkubator anaerob dan melakukan isolasi mikroba dari unit pengolahan air limbah tekstil sehingga diperoleh konsorsium mikroorganisme (mixed culture) anaerobik. Desikator dimodifikasi dengan dialiri gas nitrogen untuk menghilangkan gas oksigen di dalam desikator. Parameter yang digunakan sebagai indikator adalah pengamatan secara makroskopis, mikroskopis dan uji pembentukan hidrogen sulfida. Isolat pembanding yang digunakan adalah Pseudomonas aeruginosa sebagai bakteri aerob obligat, Escherichia coli sebagai bakteri anaerob fakultatif, Desulvofibrio desulfuricans dan Methanobrevibacter ruminantium sebagai anaerob obligat. Desikator termodifikasi juga digunakan sebagai inkubator untuk melakukan isolasi. Hasil penelitian menunjukkan bahwa desikator yang dimodifikasi mempunyai efektivitas sebagai inkubator anaerob meskipun bakteri obligat aerob dan aerob fakultatif masih dapat tumbuh karena pada media yang digunakan masih terdapat oksigen terlarut yang ditandai dengan warna pink di bagian atas media dan lilin dinyalakan di dalam desikator dapat juga digunakan sebagai indikator keberadaan oksigen. Desikator ini juga menunjukkan efektivitas untuk digunakan sebagai inkubator anaerob. Pada proses isolasi dari pengolahan limbah anaerob pabrik tekstil diperoleh 6 jenis isolat yang dapat digunakan sebagai konsorsium mikroorganisme (mixed culture) anaerobik.

Sekolah Mutiara Harapan (SMH) adalah sekolah non-profit yang didirikan dan didanai oleh PT. Riau Andalan Pulp and Paper Pangkalan Kerinci Riau, yang mengakomodasi kebutuhan pendidikan anak-anak karyawan. Komunitas SMH terdiri dari orang Indonesia dan expatriat, oleh karena itu kurikulum di SMH terdiri dari kurikulum nasional dan internasional.Senior High /SH-SMH menggunakan Cambridge curriculum dan Kurikulum Tingkat Satuan Pendidikan (KTSP). Kurikulum internasional Cambridge, menitikberatkan kemampuan siswa dalam pemahaman, pengetahuan, keterampilan dan berpikir kritis. Pengumpulan data penelitian menggunakan dokumentasi, observasi, dan wawancara. Metode analisis data menggunakan teknik triangulasi. Penelitian ini berlokasi di SMH Riau, sedangkan subjek dalam penelitian ini adalah guru kimia dan siswa XI dan XII IPA tahun ajaran 2015/2016.Hasil penelitian menunjukkan bahwa minat siswa SMH cukup tinggi untuk mengikuti kelas chemistry As/A level, namun hanya sedikit siswa yang mengikuti Cambridge International Examination. Hal ini disebabkan oleh beberapa faktor diantaranya: biaya, minat, kemampuan, dan faktor eksternal. Chemistry As/A level benar-benar mempersiapkan siswa untuk melanjutkan ke tingkat perguruan tinggi, dimana dapat dilihat dari segi tujuan, isi, metode, dan evaluasi.

The aim of this project work is to convert waste plastics into useful fuel range hydrocarbon mixture. The catalytic cracking process of polypropylene plastic waste (mineral water cup) was performed in a fixed-bed reactor with bentonite catalyst, at five temperatures ranging from 150 to 350oC with percent catalyst of 4%.The amounts of liquid fuel produced, as well as the compositions of the resulting liquid fuel, were determined by Gas Chromatography-Mass Spectrometry. The influences of cracking parameters, such as temperature and catalyst mass, on product yields were investigated. The optimum conditions cracking of polypropylene plastics waste with bentonite as catalyst is at temperature of 350oC with 4% catalyst mass or20 grams. The highest liquid yield (41.5%) was obtained using 20 gram Bentonite catalyst at 350oC. The highest percent composition of C6H14, C7H16 andC8H18 in liquid product is 16.92%, 18.48%, and 12.22% respectively at temperature of 350oC.

Dinas Kesehatan (Dinkes) Jatim dan Badan Nasional Narkotika (BNN) Jatim menunjukan bahwa jumlah mencapai 238.680 orang atau 27,3 persen dari pengguna narkoba Jatim sebanyak 884.000 orang (Jatim newaroom, 2017). Badan Narkotika Nasional Kota (BNNK) Surabaya, menemukan peningkatan penyalahgunaan narkoba dalam dua tahun terakhir. Di tahun 2016 di temukan 84 pelajar di kota surabaya menjadi pengguna narkoba dan sedang menjalani proses rehabilitasi. Dari jumlah itu menunjukan peningkatan pada tahun 2017 yaitu 101 pelajar dengan kecanduan narkoba dan pil dobel L. Kebanyakan dari mereka adalah pelajar dari 4 SD, 63 SMP, 34 SMA (Jatimtimes,Surabaya 2018). Semakin meningkatnya penyalahgunaan napza dikalangan remaja di sebabkan oleh faktor-faktor pencetus seperti depresi, kegagalan dalam pencapaian harapan, kondisi fisik, psikologis, sedangkan untuk faktor pendukung diantaranya: perpisahan orang tua, pengaruh lingkungan sekitar dan sekolah, gaya pergaulan, adanya pembulian, dan pengaruh teman sebaya. Remaja merupakan usia rentan terpengaruhi oleh hal baru tidak terkecuali rasa ingin tahu mengenai banyak hal yang menurutnya menarik untuk di coba, seperti (alkohol, sabu, narkoba, obat/pil terlarang). Mereka menganggap bahwa dengan mengonsumsi itu semua kan membuatnya merasakan sensasi seperti fly atau melayang dan menghilangkan sedikit pikiran dalam otak yang selama ini menumpuk. Pencegahan pengguna napza pada remaja sebagian besar bias dilakukan dengan menggunakan mekanisme koping yang positif antara lain olahraga, bercanda, dan bercerita. Untuk meningkatkan kemampuan mekanisme koping pada remaja dibutuhkan sosialisasi yang maksimal, sehingga dapat menggunakan mekanisme koping yang benar dalam pengambilan keputusan suatu permasalahan.

The objective of this research was to study the effect of bokashi livestock on the growth and yield of tomatoes. The experiment was conducted in Bandar Lampung from October 2009 until February 2010. The experimental design was randomized complete block design with 3 replications. The treatments were: control; inorganic fertilizers at a recommended rate of (kg ha-1) 135 N, 75 P2O5, and 110 K2O (RR); chicken manure bokashi + RR; chicken manure bokashi + 50% RR; cow manure bokashi + RR; cow manure bokashi + 50% RR; sheep manure bokashi + RR; sheep manure bokashi + 50% RR; horse manure bokashi + RR; horse manure bokashi + 50% RR. Each bokashi treatment was applied at the rate of 20 ton ha-1. The result of experiment showed that chicken manure bokashi was the best among bokashi livestock. The application of 50% RR combined with chicken, cow, sheep or horse manure bokashi gave a higher yield than treatment with inorganic fertilizer at recommended rates. These results demostrated that the application of bokashi livestock could potentially reduce the use of inorganic fertilizers while maintaining higher yield. Keywords: animal manure, inorganic fertilizer, bokashi livestock, tomatoes