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T cell concerned with cell mediated immunity and B cell concerned with humoral antibody are classified by scanning electron microscopy of the surface structure of lymphocytes using E binding lymphocytes and EAC (sensitized sheep erythrocytes treated with complement) binding lymphocytes. For the purpose to elucidate morphological differences between T cell and B cell the scanning electron microscope observations were carried out with the blast forming lymphocytes incubated in the presence of PHA. As a result it has been demonstrated that T cells have short microvilli on the cell surface, but the reason for the difference in the number of the microvilli is unclarified. Even T cells have sometimes long microvilli in the younger stage, they are longer and more slender than those of untreated peripheral B cells.

純ゴム配合の加硫ゴムのアセトン抽出物から未変化の促進剤自身と, 促進剤から加硫反応中に変化して出来た生成物を, 既に報告した部分アセチル化ロ紙クロマトグラフ法を応用して検出した. チアゾール系の促進剤を用いた時は, DMとMの他にMZを主成分として得た, チアゾール系の中, スルフェンアミド促進剤はその構成成分てあるアミンも検出した. チウラム系促進剤TS, TTを使用した時は, TS, TTの他に主成分としてPZを得た. H,D,C等の促進剤を使用した時は, 各々の促進剤を検出した. 混合促進剤を使用した場合も, その構成成分であるもとの促進剤およびそれらからの生成物を検出した. 以上の結果から部分アセチル化ロ紙クロマトグラフ法は十分実用に供し得ることを認めた. またチアゾール系, チウラム系促進剤の場合は促進機構について重要な知見を得ることが出来た.

In order to re-educate the spinal cord bladder, it is important to realize which type the cord bladder belongs to, either automatic or autonomous.The more correct information is obtained from cystometry, as a direct method, for differentiation between them.Anal reflex, ice water test, and the testicles squeezing test were done as simple clinical tests, comparing with the results of cystometry.Presence of anal reflex was well coincident with the automatic bladder, but there are some exceptional cases. Ice water test was not satisfactory for differentiation of bladder type, because the test was positive only in severe hypertonic bladder.The testicles squeezing test was always negative in the complete paraplegic cases with the lesion over the lower third of Th. segment level.However, the test was negative in many complete paraplegic cases with the lesion below L1 segment level.So, further studies are required on it's clinical significance. It was observed by cystometry of automatic bladder that contraction of detrusor muscle (increase in pressure) was not developed by the trigger action for micturition, such as percussion, massage and so forth.Therefore, it is speculated that the opening at the internal urethral orifice is primarily significant for micturition of paraplegia.

Summary1 From a room of 4 bronchial asthma patients were isolated and cultured 120 strains of fungi, including penicillium, aspergillus, cladosporium, chaetomium, etc. Among them was found a new strain of Oospora, which was designated Oospora astringenes Yamamoto. 2 Culture broths of these 120 strains were investigated as to their action on the tracheal muscle preparation from the guinea pig. A marked contracting action was observed for culture broths of Oospora astringenes, one species of penicillium, 3 species of aspergillus, and one species each of trichoderma and fusarium. Culture broths of one species of penicillium and 2 unclassified strains relaxed the tracheal muscle remarkably. 3 Three new isocoumarine derivatives were discovered in the metabolites of Oospora astringenes. Their chemical properties were clearly identified, and they were designated Oosponol, Oospolactone and K-I, respectively. Oosponol strongly contracted the tracheal muscle preparation in the in vitro experiment. This action is co...