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40 female Ss were given a 15-item modification of the Betts Vividness of Imagery Scale (1909), Gordon's Test of Visual Imagery Control (1949), and the Barber Suggestibility Scale (BSS; 1965). BSS subjective scores were positively correlated with vividness of imagery but negatively correlated with control of imagery. BSS objective scores did not correlate with either of the imagery variables. Marginal support was obtained for a hypothesis advanced by Richardson (1969) that Ss high on vividness but low on control of imagery would show greater suggestibility than would Ss possessing any other combination of these 2 characteristics.

The phage particles which attack Rhizobium japonicumwere isolated from soybean (Glycine maxL. Merrill) nodules and rhizosphere soil to study the relationship to the serological groups of R. japonicumpresent in these samples. Phages were isolated from chloroform-treated samples using eight host strains of R. japonicumin a double-layer agar method. These strains belonged to seven serogroups common in Iowa soils.

Rhizobium japonicumstrains 117 and 138 (USDA) were used in equal proportions to inoculate soybean seedlings. Preparations of individual nodules were stained with strain-specific fluorescent antibodies and rhizobia present were identified by direct microscopic examination using transmitted tungsten (darkfield) light and reflected near-ultraviolet light singly and in combination. At an inoculation density of 108rhizobia per plant, 32 percent of the nodules contained both strains. The percent double infection decreased as inoculum density decreased. Strain 138 generally predominated over strain 117 in accounting for the majority of the nodules that contained only one strain, and cells of 138 were generally numerically predominant in nodules that contained both strains. Streak plate cultures of selected nodule slurries provided data that fully reinforced the fluorescent-antibody data.

Equations relating the magnetic resonance spectral parameters N and L of the AA'BB' system to the conformational populations of 1,2-disubstituted ethanes of the type XCH2CH2Y are derived for a variety of substituents. These equations are used to obtain conformational information for choline, tryptamine and tyrarnine derivatives in solution.

Endogenous uterine cyclic GMP and cyclic AMP concentrations were monitored at each stage of the estrus cycle; cyclic GMP concentrations were found to be highest and cyclic AMP concentrations lowest during proestrus when plasma estrogen levels have been shown to be maximal. After administration of estradiol-17β or diethylstilbestrol, the concentrations of uterine cyclic GMP in ovariectomized rats underwent a progressive and significant elevation and the levels of cyclic AMP declined significantly below control values when near maximal accumulation of tissue cyclic GMP was achieved. The increase in uterine cyclic GMP concentrations produced by estradiol benzoate administration was prevented when progesterone and the estrogen were co-administered. These results raise the possibility that an enhanced cellular accumulation of cyclic GMP may be involved in the expression of some of the actions of estrogen in uterine tissue.

Previous reports, concerning the operation of choledochoduodenostomy have stressed the importance of an ‘adequate’ stoma. However, there does not appear to have been an attempt to measure the stoma size by some objective method.The results with a new technique for the assessment of the stoma and duct system postoperatively are reported. The method involves the use of a transnasal guided catheter system with selective catheterization of the common bile-duct via the stoma. Accurate delineation of the stoma and ducts is then possible.The stoma was successfully catheterized in 13 out of 16 attempts, and satisfactory radiographs were obtained in 1 other patient by a modification of the technique. The measurements of the maximum diameter of the stoma were considerably less than those reported previously; despite this the clinical result in the short term was good in all except the 2 patients in whom the stoma could not be demonstrated.

Dog red cells heated at 49 C. for 15 minutes with no change in osmotic fragility, showed a decreased rate of survival in vivo, and increased sequestration by the spleen, and an increase in the osmotic fragility when recovered from the spleen. The peripheral blood showed normal osmotic fragility at all times. These changes were comparable to those seen in the spleen in homozygous sickle-cell disease and hereditary spherocytosis. There was no hemoglobinemia. Splenectomy decreased the rate of destruction of such heated red cells in vivo. In these studies the rigidity of the red cells with increased viscosity, but with normal osmotic fragility, may have resulted in the removal of the heated red cells by the spleen and subsequent conditioning of these cells in the spleen. In contrast to the 15 minutes heating, dog cells heated at 49 C. for 60 minutes had increased osmotic fragility and were rapidly removed from the circulation. There was sequestration by the spleen or by the liver with hemoglobinemia. The red cells with the greatest increase in osmotic fragility were not preferentially removed in vivo.

Comparative studies were made to determine the relative efficiency of different laboratory tests in detecting Rhizobium melilotiwhen alfalfa seeds were inoculated with known numbers of bacteria. The bottomless bottle (modified Leonard) and crock techniques, which utilize more than one seed per container, overestimated the number of rhizobia present on alfalfa seeds due to the transfer of rhizobia among seedlings in the test container. The transfer effect probably was due to root growth accompanied by multiplication and movement of rhizobia. Positive results (nodulated plants) in a container indicated that at least one seed carried one rhizobium. When rhizobia were present on the seed, a container with one inoculated seed gave results that were not significantly different from the results obtained when all seeds were inoculated. The agar tube technique tended to underestimate the number of rhizobia present on alfalfa seeds because the anaerobic conditions in the support medium inhibited nodule formation. The sand tube technique gave the most accurate information.

Opacification of the rabbit lens was studied as a function of dose and time post irradiation for single and fractionated doses of 1 MeV X-rays, 20 and 100 MeV protons. The degree of opacification was found to be a function of time, radiation dose, LET and mode of dose deliverance. Fractionation reduced the final degree of lens opacification by a factor of 2 or less, depending upon the dose and type of radiation.

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A remarkably reversible slip-unslip process has been observed on low strain amplitude fatigue hardened copper single crystals. Slip lines formed on an electropolished surface in one half cycle almost vanish on the subsequentreverse half-cycle, then reappear on the next forward stroke. This process has been observed at least 300 μ below the original surface shortly after saturation. The dislocation structure was composed of dense dipole-monopole mats elongated on the primary slip plane and it is suggested that the reversibility results from interactions between these mats and their surrounding elastic matrix.

THE concepts upon which an adequate program for prevention of rheumatic fever can be based were discussed in a previous report.1 These concepts have been almost universally accepted by workers in the field of rheumatic fever, yet they have not been widely applied in actual practice. In general, the programs for the prevention of primary rheumatic fever can be categorized into: (1) school-oriented programs as described by Phibbs;2 (2) mass prophylaxis as used by the armed services;3 (3) mass treatment of streptococcal epidemic areas as described by Zimmerman and Sciple;4 and finally, (4) adequate detection and treatment of streptococcal disease in private physicians' offices.1,5-7For each of these approaches, the indications, practicality, and effectiveness depends on variables such as socioeconomic conditions, availability of medical care, and motivation of the community. In some situations a combination of these approaches may be indicated. However, the scope of

In 1927, in a classic paper, Hahn and Gillespie 19 clearly defined the basis of the anomalous physical behavior of the sickle cell as an abnormality of its hemoglobin when in the deoxygenated state and pointed to the affected cells as the primary cause of the characteristic hemolytic anemia. From microscopic observations of drops of blood suspended in a gas chamber and from the results of the removal of a large spleen from a child with sicklemia, they were led to make the following statement: Sickle cell formation is a reversible phenomenon depending on the free or combined state of the hemoglobin of the susceptible corpuscles. When the hemoglobin is in the combined state, the discoid form is stable; when in the uncombined state, the distorted form is stable. The behavior of the susceptible corpuscles toward oxygen asphyxia thus constitutes a special application of a hypothesis correlating contour with

Hereditary spherocytosis (congenital hemolytic jaundice) is an inherited disease entity characterized by chronic anemia, by increased hemolysis and erythropoiesis, and frequently by splenomegaly. The classic feature of this disease is the presence in the peripheral blood of red cells that are spheroidal in shape 1 and that are unusually susceptible to hemolysis when suspended in hypotonic media.2 These two abnormal prop- erties have been shown to be mutually interdependent, the increased osmotic fragility reflecting the fact that the surface membrane of the erythrocyte is reduced in size relative to its volume,* with the result that its capacity to swell before reaching the rupture point is reduced. Also, these cells are abnormally susceptible to trauma, having an increased "mechanical fragility." Moreover, when blood from these patients is incubated at 37.5 C there occurs a pronounced increase in the osmotic and mechanical fragility of the red cells which surpasses to a

The general problem of reducing data available in the integrated circuit environment is addressed. One can consider the circuit to be essentially composed of identification and performance data. Opportunities exist at every level of manufacturing and testing to aid in the final interpretation of the results. Without disturbing the technology or actual circuit design, some general methods for improving testing techniques are discussed. Examples of data reduction and presentation techniques are given where relation between performance and identification can be seen.

Changes in the physical properties of red cells were produced by chemical fixation, the sickling process, by suspension in hypertonic sodium chloride and by a combination of hypertonicity and sickling. These resulted in a loss of deformability or increased rigidity of cells as indicated by a rise in viscosity of cell suspensions and hemolysates, more Newtonian flow, diminished filtration of cell suspensions through microfilters, resistance to packing by centrifugal force and abnormal susceptibility to mechanical trauma. The results of these studies show that in hypertonic sodium chloride all cells have an increased viscosity and are more rigid. The relationship of these physical properties to the behavior of cells in the microcirculation is discussed for normal subjects and those with sickle cell disease, including the effect on the kidney.

Heating of human or dog red cells at 49 C. for 15 minutes or 60 minutes increased resistance to packing by a centrifugal force, increased viscosity and deformed them. After 15 minutes of heating, osmotic fragility was usually normal but was elevated after 60 minutes with the formation of spheroidal cells. The increase in viscosity caused by heating red cells at 49 C. for 60 minutes did not appear to result from the effect of heat on the hemoglobin or the hemolysis products of red cells disrupted by sonic treatment. The heating of intact human or dog red cell stroma in serum, or stroma washed multiple times in physiologic saline however, regularly increased their viscosity and produced buds and microstroma. The rigidity of stroma was increased by heating, probably accounting for the increased viscosity of heated intact red cells. The rigidity of heated stroma of red cells was further demonstrated by showing that the shape changes of the sickling process could be prevented in large part by the heating of sickle cells. Heating did not, however, prevent tactoid formation in stroma-free sickle-cell hemoglobin solutions.

Placement of fertilizer in relation to the seed of most agronomic crops has been studied extensively. Limited information is available concerning the placement of fertilizer for soybeans. Fertilizer treatments consisting of banded starter, starter in contact with the seed, and a combination of banded and seed placement were superimposed on broadcast fertilizer treatments at three locations. Responses varied depending on environmental factors. With low rainfall and a low soil test P level, the largest response was from broadcast fertilizer. Starter fertilizer had less effect on seed yields either with or without broadcast fertilizer even though both starter and broadcast effects were significant. With adequate rainfall and a low P level, the largest response was to combinations of starter and broadcast fertilizer. Yields were increased by as much as 746, 598, and 941 kg/ha with band, seed placement and broadcast treatments, respectively. When P and K levels were very high, no yield increases were obtained from any fertilizer placement. In fact, seed placement without broadcast or seed placement and/or band in combination with broadcast decreased yields significantly in many cases. Three soybean [Glycine max(L.) Merrill] varieties were used at each location and the responses were different depending on varieties. The largest yield increases were obtained with ‘Corsoy’ and ‘Hark’ varieties.