Search

The experiments dealt with lipid synthesis and cholesterol uptake in human coronary arteries without evidence of atherosclerosis and in human saphenous veins perfused in vitro with pulsatile pressure. The results demonstrate the following: 1.1. Human coronary arteries without evidence of atherosclerosis and atherosclerotic coronary arteries are unable to synthesize cholesterol from acetate. 2.2. Synthesis of cholesterol esters is small in coronary arteries regardless of the presence or absence of atherosclerotic lesions. 3.3. Identical uptakes of cholesterol were found in normal and atherosclerotic coronary arteries. 4.4. Lipid synthesis in human saphenous veins perfused at a pressure of 4535 mm Hg does not differ from that in nonatherosclerotic coronary arteries or saphenous veins perfused at a pressure of 130100 mm Hg. 5.5. Cholesterol uptake in saphenous veins perfused at a pressure of 4535 mm Hg is lower than that in coronary arteries or saphenous veins perfused at arterial pressure (130100 mm Hg.

Dislocation images in the high resolution scanning electron microscope with conventional filament have been obtained in transmission and back scattering modes from thin molybdenite crystals. Thick crystals show overwhelming topology contrast from surface steps and imperfections.

A spherical retarding-field electron energy analyser has been constructed to investigate the backscattering and transmission of electrons in the energy range 10-30 keV. It consists of full-spherical meshes with collector, and attains a resolution of about 2%. By using this apparatus, the energy distribution of electrons backscattered from C, A1, Cu, Au and Cu-Au alloy specimens is obtained. Results are compared with those obtained from Monte Carlo calculations.

Neurologic complications of fracture of the pelvis are an entity rarely discussed and likely to be undiagnosed because of being obscured by the associated severe bony and soft tissue injury and because of a lack of awareness of the possibility of nerve demage.We encounted 5 cases of nerve injury as a result of fracture of the pelvis at the Kumamoto Rosai Hospital over the year 1968 to 1969.Classifying fractures of the pelvis in our cases, 2 cases had Malgaigne's fractures and one case separation of the symphysis pubis with fractures of the pubic rami and the ischium. Other two cases had fracture from the ilium to the acetabulum and fracture of the pubic rami and the ischium. All fracture of our cases correspondingly severe with the pelvic ring continuity brocken anteriorly or posteriorly. Although it is difficult to explain accurate level of the lesion in our cases, perhaps the lesion is thought to be due to damage at the plexus level.Especially the lumbosacral trunk was involved in all of our cases. The nerve damage was incomplete. All of the cases were treated with the conservative methods.The prognosis of this injury is comparatively good, although there may be weakness in the leg and hypesthesia in the foot. But the functional results of all cases are good, two cases returning to heavy work.

This paper deals with a problem on the learning characteristics of human operator in a compensatory tracking control task.It is already known that the human operator can learn and adapt himself to changes in control dynamics.It is therefore essential for a system designer to analyze the learning behavior of the human operator. However, the process of learning has not been nivestigated in much detail. A new method to assess the learning process of a human operator is proposed here by fitting the experimental curve to logarithmic function. Variations of the coefficients are then considered to provide a measure for the learning speed.The new method of evaluating the learning process is applied to the cases of step response and frequency response. Also, in order to reduce the training interval, the method of performance scores display is used for the detection of optimal switching point in a relay control system. The result of these investigations presented in this paper are expected to be of use in the design of man-machine systems.

The two-beam dynamical theory of electron diffraction in absorbing crystals has been applied to explain features of bend and thickness extinction contours and of images of stacking faults observed on transmission electron micrographs of metal foils. Inelastic scattering processes affect the intensities of the elastically scattered waves and give rise to 4 anomalous ’ transmission (Borrmann) effects. The formal theory takes account of these effects phenomenologically by the use of a complex lattice potential but ignores the contribution of the inelastically scattered electrons to the image. In the theory absorption is described by certain parameters ξ' 0 and ξ' g with dimensions of length. These parameters are determined by Fourier coefficients of the imaginary part of the potential in the same manner as the extinction distance ξ g is determined by the Fourier coefficient of the real part. A simple physical explanation of the ‘anomalous’ absorption effect is developed in terms of the two crystal wave fields. This explanation is particularly helpful in understanding details of bend and thickness contours and of images of stacking faults. The theory is at present phenomenological because the detailed mechanism of the absorption process is not understood. Nevertheless, comparison of the theory with observations enables the absorption parameters to be roughly estimated.

Dislocation images from thin molybdenite crystals showing apparent depth-dependent black-white contrast in qualitative agreement with theoretical predictions, have been observed in transmission, back-scattering and secondary electron emission modes using a high resolution scanning microscope with conventional filament.

The behavior of progressive waves moving through a circular pipe containing a rotating flow of water with an axial cavity is studied both theoretically and experimentally. The theoretical solution is based on an empirical relation for the rotational velocity distribution in the water along a radius between the cavity and the pipe wall, where this relation is in the form of a quadratic function fitted to experimental data. The frequencies of the progressive waves are determined experimentally from observation of the wave motion on the surface of the axial cavity. Comparison with the frequencies predicted by the theoretical solution show a satisfactory agreement. The agreement is much poorer if the rotational velocity is simply assumed to be equivalent to that induced by a potential flow vortex along the axis of the pipe.

Nach einer Ubersicht uber die Informationsmoglichkeiten der Elektronenstrahlmikroanalyse wird eine neue Methode der stereoskopischen Detektion von der Probenoberflache ruckgestreuter Elektronen dargestellt. An Hand von Beispielen wird gezeigt, das dadurch eine gute Unterscheidung zwischen Oberflachentopographie und chemischer Zusammensetzung der Gefugebestandteile an der Probenoberflache moglich ist.

The dynamical theory of electron diffraction including a term to take account of absorption has been applied to explain some contrast anomalies observed at extinction contours and stacking faults on transmission electron micrographs of metal foils. The theory is at present phenomenological because the detailed mechanism of the absorption process is not understood. This paper reports some preliminary results of the theory and compares them with observations.

A report is made of a mass screening study for uterine carcinoma on 3,725 women by a new self-collecting smear method, i.e., the sponge-cytocylinder technique, whereby 15 cases of cervical carcinoma (0.58 per cent) and nine cases of cervical dysplasia (0.39 per cent) have been detected in 2,560 women examined on the first screening. Cases of cervical carcinoma encountered include seven of carcinoma in situ and four of early invasive carcinoma, both of which accounted for 73.3 per cent of the total cases of cancer. The second screening included 1,165 women, at one- or two-year intervals; it revealed two cases (0.17 per cent) of carcinoma in situ and two cases of cervical dysplasia.

An ``x‐ray microscope'' which can take both x‐ray diffraction patterns and magnified Laue‐diffraction images of selected areas of the specimen under microscopic observation has been constructed. Resolving power of the microscope is 0.3 μ and the minimum diameter of the selected area of the specimen is about 10 μ. A decontamination device for the target is incorporated into the instrument. Some applications of the methods of x‐ray microscopy, selected‐area diffraction, and magnified Laue diffraction are described. It is shown that the selected‐area diffraction patterns are useful for the identification of the components of the specimen with complicated structure. It is also shown that the magnified Laue‐diffraction images are useful for the study of imperfections and local distortions in crystals.

By providing a predictive display to human operator, man-machine systems are known to improve their control characteristics. In this paper a few, slightly new ways of organizing such “predictive man-machine systems” are proposed. Some experiments were conducted on such systems and results are analyzed for quantitative evaluation of the predictive displays. As expected, such displays are found to be quite effective for complex controlled elements. They also help make learning process shorter. It is pointed out that the predictive span should be an appropriate one, matching the plant to be controlled.

The dynamical theory of electron diffraction is applied to the interpretation of electron microscopic images of moire patterns. Two cases often observed are treated. One is the case where two plate-shaped crystals are superposed closely without a vacuum layer between them and another is the case where two crystals are superposed with a vacuum layer between them. Resolved lattice images of two superposed crystals are also interpreted. The intensity profiles of the images vary with the thicknesses of the crystals and vacuum layer and with the deviation from the Bragg angle. The shifts of the fringes and anomalies of the contrast which are expected from the present theory were observed in the electron microscopic images of moire patterns of cupric sulphide, palladiumgold and platinum-phthalocyanine. The relation between moiré patterns and crystal structure is also discussed.

The investigation described in this paper aimed at obtaining informations of control behavior of human operator in intermittent input control system. The dynamic researches on such a problem have been carried out as sampled data system.However few investigations have been carried out so far on such a problem as intermittent input information control system. For the design of such a system thefundamental analysis of the man-machine system as a whole is essential. Some new characteristics are obtained from the experimental results.

A derivative of the R factor NR1 (called R12) has been isolated which undergoes an increased number of rounds of replication each division cycle in Proteus mirabilis, Escherichia coli , and Salmonella typhimurium . The alteration resulting in the increased number of copies (round of replication mutation) is associated with the transfer factor component of the R factor. R12 has the same drug resistance pattern as NR1 , is the same size as shown by sedimentation in a sucrose gradient and electron microscopy (63 × 10 6 daltons), and has the same partial denaturation map. The level of the R factor gene product chloramphenicol acetyltransferase has been examined in P. mirabilis and was found to be consistent with gene dosage effects. The plasmid to chromosomal deoxyribonucleic acid ratio of NR1 increases several fold after entry into stationary phase, whereas this ratio for R12 remains approximately constant. Individual copies of R12 are selected at random for replication from a multicopy plasmid pool. A smaller percentage of R12 copies replicate during amino acid starvation than has previously been found for NR1 in similar experiments.

Guinea pigs were injected intravenously with Evans blue solution (1/2), 1, 5 and 22 hours after intradermal injection of Vibrio cholerae 569B toxin. Then they were fixed by perfusion with diluted Karnovsky's aldehyde mixture 1(1/2), 5, 10, 15 and 90 minutes later. In some cases, horseradish peroxidase was mixed in the dye solution, and chopped tissue slices were incubated histochemically. Dermal blood vessels from these samples were examined under the electron microscope. The fine structure of the endothelial junctions remained unchanged as compared with controls. However, extended rough surfaced endoplasmic reticulum was observed in the endothelial cells at 30 minutes after the toxin injection, when cutaneous bluing was not marked yet. At 22 hours after toxin injection, endothelial perikarya were filled with prominent Golgi complexes, multivesicular bodies and systems of caveolae and vesicles which coalesced, forming intraendothelial channels after diaphragms disappeared. Endothelial fenestrae were numerous in the attenuated portions.