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1. Fifteen sheep foetuses of 1·5–5·2 kg body weight were prepared with indwelling arterial and venous catheters for experimentation one to six days later.

In the conscious, nonmedicated sheep fetus, blood volume strongly influences placental blood flow, a change of 1% in volume being associated with a change of 1.7 ± 0.1% in flow. This relationship is valid between blood volumes of 80 to 110% of normal, is independent of time over a period of several days and independent of concomitant changes in fetal hemoglobin concentration.We are indebted to Mr. Frederick Arfmann, Dr. J. Metcalfe and Mrs. Alice Fitzgerald for help with this study.

The various types of materials that have been used to seal bridge joints have been reviewed. Some of the bridge engineers joint material requirements have been listed together with the advantages and disadvantages of the three most widely used bridge joint sealants being specified and used today. It is felt that the cold applied two component asphalt-modified polyurethane sealants come closest to answering the needs for a bridge joint sealant over the other types of materials.

It is conceivable that preoccupation with the granular pneumocyte's role in the reactions to alveolar injury is premature; perhaps it is even irrelevant. However, there is sufficient evidence to justify at least some additional probing into the possibility that this cell has an important reparative function unrelated to surfactant synthesis. A better understanding of this function may also contribute to clarification of the relationships between organizing interstitial pneumonia and such reactions as desquamative interstitial pneumonia and pulmonary alveolar proteinosis in which the granular pneumocyte is especially prominent.