Search

Your search keyword '"G, Bonelli"' showing total 14 results
Start Over Author "G, Bonelli" Publication Year Range More than 50 years ago
14 results on '"G, Bonelli"'

1. Further observations on the effects of trypsin on the volume and functions of mitochondria isolated from normal liver and AH-130 Yoshida ascites hepatoma

Author

F, Feo, G, Bonelli, R A, Canuto, and R, Garcea

Subjects
Adenosine Triphosphatases, Carbon Isotopes, Carcinoma, Hepatocellular, Membranes, Liver Neoplasms, Phosphotransferases, Cytochrome c Group, Dextrans, Digitonin, Mitochondria, Liver, Succinates, Neoplasms, Experimental, Permeability, Cell Line, Rats, Electron Transport Complex IV, Phospholipases, Animals, Trypsin, Mitochondrial Swelling, Cytochrome Reductases
Published
1973

2. Effect of trypsin on morphological integrity and some functional activities of mitochondria from normal liver and AH-130 Yoshida ascites hepatoma

Author

F. Feo, G. Bonelli, and A. Matlí

Subjects
Sucrose, Carcinoma, Hepatocellular, Mitochondria, Liver, Mitochondrion, Biology, In Vitro Techniques, General Biochemistry, Genetics and Molecular Biology, chemistry.chemical_compound, Oxygen Consumption, Glutamates, medicine, Inner membrane, Animals, Trypsin, General Pharmacology, Toxicology and Pharmaceutics, Peritoneal Neoplasms, chemistry.chemical_classification, Carbon Isotopes, Liver Neoplasms, General Medicine, Neoplasms, Experimental, Rats, Membrane, Enzyme, chemistry, Biochemistry, Spectrophotometry, Liberation, Indicators and Reagents, Swelling, medicine.symptom, Mitochondrial Swelling, medicine.drug
Abstract

The effect of trypsin on morphological integrity and certain functional activities of mitochondria from normal liver and AH-130 Yoshida ascites hepatoma, has been studied. Liver mitochondria are barely attacked by trypsin which induces swelling only id added in large amounts. The swelling is preceeded by a lag phase during which liberation of little amounts of ninhydrin reacting compounds occurs. Tumour mitochondria are highly sensitive to trypsin, which induces immediate swelling even if added in amounts as little as 0.9 μg/mg protein. Evidence is provided that in tumour mitochondria trypsin induces damage of inner membrane permselectivity towards sucrose, and respiratory inhibition, also when it fails to inactivate the external membrane enzyme, NADH:cytochrome c reductase. The results are interpreted as indicative of the existence of a different structural state in membranes of normal and tumour mitochondria.

Published
1970

5. Effect of chemical, physical and enzymic treatments on lysosomes from AH-130 yoshida ascites hepatoma

Author

F. Feo and G. Bonelli

Subjects
Carcinoma, Hepatocellular, Hot Temperature, Acid Phosphatase, Cellular and Molecular Neuroscience, Ascites, medicine, Animals, Polycyclic Compounds, Trypsin, Molecular Biology, Glucuronidase, Pharmacology, Chemistry, Liver Neoplasms, Digitalis Glycosides, Cell Biology, Neoplasms, Experimental, Hydrogen-Ion Concentration, Rats, Enzyme Activation, Biochemistry, Hypotonic Solutions, Phospholipases, Molecular Medicine, medicine.symptom, Lysosomes
Abstract

Omogenati e frazioni L di epatoma ascite di Yoshida AH-130 sono piu resistenti di quelli di fegato all'attivazione termica a pH 5, al trattamento ipotonico ed alla digestione con tripsina.

Published
1971

7. [Epidemiology of malignant tumors of the breast]

Author

A P, Cappa, E, Anglesio, M, Panero, and G, Bonelli

Subjects
Adult, Male, Asia, Adolescent, Infant, Breast Neoplasms, Middle Aged, South America, Europe, Child, Preschool, Africa, North America, Humans, Female, Child, Aged
Published
1971

9. Effect of chemical, physical and enzymic treatments on lysosomes from AH-130 yoshida ascites hepatoma.

Author

Feo F and Bonelli G

Subjects
Animals, Enzyme Activation, Hot Temperature, Hydrogen-Ion Concentration, Hypotonic Solutions, Liver Neoplasms, Lysosomes drug effects, Neoplasms, Experimental enzymology, Rats, Acid Phosphatase metabolism, Carcinoma, Hepatocellular enzymology, Digitalis Glycosides pharmacology, Glucuronidase metabolism, Lysosomes enzymology, Phospholipases pharmacology, Polycyclic Compounds pharmacology, Trypsin pharmacology
Published
1971
Full Text
View/download PDF

10. [Epidemiology of malignant tumors of the breast].

Author

Cappa AP, Anglesio E, Panero M, and Bonelli G

Subjects
Adolescent, Adult, Africa, Aged, Asia, Child, Child, Preschool, Europe, Female, Humans, Infant, Male, Middle Aged, North America, South America, Breast Neoplasms epidemiology
Published
1971

13. Further observations on the effects of trypsin on the volume and functions of mitochondria isolated from normal liver and AH-130 Yoshida ascites hepatoma.

Author

Feo F, Bonelli G, Canuto RA, and Garcea R

Subjects
Adenosine Triphosphatases metabolism, Animals, Carbon Isotopes, Cell Line, Cytochrome Reductases metabolism, Cytochrome c Group, Dextrans, Digitonin pharmacology, Electron Transport Complex IV antagonists & inhibitors, Liver Neoplasms, Membranes drug effects, Mitochondria, Liver enzymology, Mitochondrial Swelling drug effects, Neoplasms, Experimental, Permeability, Phospholipases pharmacology, Phosphotransferases antagonists & inhibitors, Rats, Succinates, Carcinoma, Hepatocellular, Mitochondria, Liver drug effects, Trypsin pharmacology
Published
1973

14. Effect of trypsin on morphological integrity and some functional activities of mitochondria from normal liver and AH-130 Yoshida ascites hepatoma.

Author

Feo F, Bonelli G, and Matlì A

Subjects
Animals, Carbon Isotopes, Glutamates metabolism, In Vitro Techniques, Indicators and Reagents, Liver Neoplasms, Mitochondrial Swelling drug effects, Neoplasms, Experimental, Oxygen Consumption, Peritoneal Neoplasms, Rats, Spectrophotometry, Sucrose, Carcinoma, Hepatocellular, Mitochondria, Liver drug effects, Trypsin pharmacology
Published
1970
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results