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Your search keyword '"Fauvel, J."' showing total 9 results
Start Over Author "Fauvel, J." Publication Year Range More than 50 years ago
9 results on '"Fauvel, J."'

3. Effect of prolonged alcohol administration on calcium transport in heart muscle of the dog.

Author

Bing RJ, Tillmanns H, Fauvel JM, Seeler K, and Mao JC

Subjects
Adenosine Triphosphatases metabolism, Adenosine Triphosphate analysis, Angiotensin II pharmacology, Animals, Blood Pressure drug effects, Calcium analysis, Dogs, Hemodynamics drug effects, Mitochondria, Muscle analysis, Mitochondria, Muscle enzymology, Mitochondria, Muscle metabolism, Mitochondria, Muscle physiology, Myofibrils drug effects, Myofibrils metabolism, Oxygen Consumption drug effects, Phosphocreatine analysis, Sarcoplasmic Reticulum analysis, Sarcoplasmic Reticulum enzymology, Sarcoplasmic Reticulum metabolism, Calcium metabolism, Ethanol pharmacology, Heart drug effects, Myocardium metabolism
Published
1974
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4. The effect of prolonged administration of ethanol on cardiac metabolism and performance in the dog.

Author

Pachinger OM, Tillmanns H, Mao JC, Fauvel JM, and Bing RJ

Subjects
Adenosine Triphosphate metabolism, Administration, Oral, Animals, Aspartate Aminotransferases metabolism, Cardiac Output drug effects, Coronary Circulation drug effects, Dogs, Ethanol blood, Ethanol pharmacology, Fructose-Bisphosphate Aldolase metabolism, Glucosephosphate Dehydrogenase metabolism, Glyceraldehyde-3-Phosphate Dehydrogenases metabolism, Isocitrate Dehydrogenase metabolism, Isoproterenol pharmacology, L-Lactate Dehydrogenase metabolism, Malate Dehydrogenase metabolism, Mitochondria, Muscle drug effects, Mitochondria, Muscle metabolism, Myocardium enzymology, Oxygen Consumption, Phosphogluconate Dehydrogenase metabolism, Time Factors, Ethanol administration & dosage, Heart drug effects, Myocardium metabolism
Abstract

The effect of prolonged administration of alcohol on mitochondrial function and high-energy phosphate (ATP) of heart muscle was investigated in dogs. Animals were divided into two groups, a control group and a group that received alcohol. In the experimental series, dogs received 400 ml of a 25% solution of alcohol added to the food and drinking water. Measurements were carried out after ethanol had been withheld for 2 days. Total myocardial blood flow, cardiac output, and myocardial O(2) consumption remained at control levels. Measurement of cardiac contractility using the maximal rate of left ventricular pressure rise (dP/dt(max)) showed no change in animals exposed to alcohol. When the afterload of the heart was increased with angiotensin, a slight but not significant decline in cardiac contractility was observed. Activities of various intramitochondrial and extramitochondrial enzymes were measured in both groups. After alcohol administration, the primarily intramitochondrial isocitrate dehydrogenase diminished. ATP in heart muscle of dogs exposed to alcohol declined, and mitochondrial oxygen consumption and respiratory control indices diminished. These observations suggest that the primary lesion leading to alteration of myocardial performance is a biochemical malfunction of the mitochondria, which at this early stage is not reflected in changes in myocardial contractility.

Published
1973
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5. [Experimental study on the prolonged administration of alcohol on arterial lipids, and on cardiac ultrastructure and performance].

Author

Fauvel JM, Tillmanns HT, Pachinger O, Mao JC, and Bing RJ

Subjects
Administration, Oral, Animals, Blood Pressure drug effects, Cardiac Output drug effects, Cholesterol blood, Dogs, Ethanol administration & dosage, Fatty Acids, Nonesterified blood, Heart Rate drug effects, Mitochondria, Muscle drug effects, Myocardium metabolism, Oxygen Consumption drug effects, Phospholipids blood, Time Factors, Triglycerides blood, Ethanol pharmacology, Heart drug effects, Lipids blood, Myocardium pathology
Published
1974

6. Microcirculation in the ventricle of the dog and turtle.

Author

Tillmanns H, Ikeda S, Hansen H, Sarma JS, Fauvel JM, and Bing RJ

Subjects
Animals, Arteries physiology, Blood Flow Velocity, Capillaries physiology, Electrocardiography, Heart Atria blood supply, Methods, Motion Pictures, Physiology, Comparative, Transducers, Transillumination instrumentation, Veins physiology, Coronary Circulation, Dogs physiology, Heart Ventricles blood supply, Microcirculation, Turtles physiology
Published
1974
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7. [Prevention of rhythm disorders by a new quinidine salt with sustained-action: study of quinidinemia (apropos of 45 cases)].

Author

Salvador M, Fauvel JM, Lesbre JP, and Galinier F

Subjects
Adult, Aged, Arrhythmias, Cardiac drug therapy, Delayed-Action Preparations therapeutic use, Drug Tolerance, Female, Humans, Male, Middle Aged, Quinidine blood, Time Factors, Vitamin K antagonists & inhibitors, Wolff-Parkinson-White Syndrome drug therapy, Arrhythmias, Cardiac prevention & control, Quinidine therapeutic use, Wolff-Parkinson-White Syndrome prevention & control
Published
1971

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