Since Koch's discovery of tuberculin some seven years ago, we no longer wonder that the majority of medical men were turned away from the employment of this remedy by its ill-advised use, and the resulting gross effects, as shown by Virchow, the great pathologist. From the absurd advertisement of a Swiss barber "tuberculin injections given here," and the equally preposterous belief which at first prevailed that a means to destroy tuberculosis had been discovered, as easy of use as a household remedy, we have come to learn that if cure it will, it must be by a concentration of skilled effort, and a technique involving as much discrimination in diagnosis and care as does the differentiation of a complicated eye refraction, the microscopic determination of blood changes due to disease, the endoscopic study of internal organs, or any other delicate field of professional work. The great mistake of the celebrated