1. Absence of damage to human chromosomes by spray adhesives
- Author
-
Diana W. Bianchi, Paul S. Moorhead, and Catherine H. Donaldson
- Subjects
Genetics ,Aerosols ,Chromosome Aberrations ,Male ,Fetus ,Health, Toxicology and Mutagenesis ,Physiology ,Chromosome ,Abnormalities, Drug-Induced ,Household Products ,Environmental Exposure ,Biology ,Control subjects ,Chromosomes ,Pregnancy ,Leukocytes ,Humans ,Female ,Molecular Biology ,Metaphase ,Cells, Cultured - Abstract
Summary Examination of metaphase chromosomes of cultured leukocytes from six individuals exposed in some degree to spray adhesives compared to II control subjects showed no significant elevations of aberration frequencies. No consistent increase in abnormal chromosome numbers nor in incidence of true breaks, achromatic gaps, or other structural aberrations was revealed by pooling of data obtained. Incidental to the lack of any effect upon human chromosomes due to use of spray adhesives, the following indicates the absence of any relation to birth anomalies. A dysmorphic chromosoinally abnormal child was born to control parents in the study and a stillborn fetus with no congenital anomalies was spontaneously aborted by a subject whose husband had been exposed to spray adhesives.
- Published
- 1974