1. PREGNENOLONE AND PROGESTERONE CONCENTRATIONS IN OVARIAN VENOUS BLOOD OF THE ARTIFICIALLY OVULATED SQUIRREL MONKEY (SAIMIRI SCIUREUS)
- Author
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Bechini D and Fajer Ab
- Subjects
Ovulation ,Embryology ,medicine.medical_specialty ,Chromatography, Gas ,Gonadotropins, Equine ,media_common.quotation_subject ,Uterus ,Ovary ,Biology ,Tritium ,Injections, Intramuscular ,Veins ,Endocrinology ,Corpus Luteum ,Internal medicine ,Follicular phase ,medicine ,Animals ,Progesterone ,media_common ,Heparin ,Squirrel monkey ,Obstetrics and Gynecology ,Haplorhini ,Organ Size ,Cell Biology ,Venous blood ,biology.organism_classification ,medicine.anatomical_structure ,Reproductive Medicine ,Pregnenolone ,Female ,Chromatography, Thin Layer ,medicine.drug ,Hormone - Abstract
The secretion of pregnenolone and progesterone by artificially stimulated ovaries was studied. Ovulation was induced in 17 sexually immature squirrel monkeys by PMSG-HCG injections and pregnenolone and progesterone concentrations were determined in the ovarian venous blood by thin-layer and gas chromatography. 50 IU PMSG administered twice daily for 9 days was supplemented during Days 6-9 by twice daily injections of 250 IU HCG. The animals were killed 2 or 5 days after the last injection. 3 controls were injected with isotonic saline. There was a significant increase in the ovarian (left and right) and uterine weights in 16 of the 17 animals 2 days after treatment (p=.05; p
- Published
- 1971
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