1. Structure and mass of mitochondria in the process of compensatory hyperfunction and hypertrophy of the heart
- Author
-
F.Z. Meerson, T.A. Zaletayeva, S.S. Lagutchev, and M.G. Pshennikova
- Subjects
medicine.medical_specialty ,Cellular differentiation ,Cardiomegaly ,Electrons ,Mitochondrion ,Biology ,Muscle hypertrophy ,law.invention ,chemistry.chemical_compound ,Adenosine Triphosphate ,law ,Internal medicine ,Organelle ,Genetics ,medicine ,Animals ,Molecular Biology ,Microscopy ,Myocardium ,Research ,Proteins ,Heart ,Aortic Valve Stenosis ,DNA ,Hypertrophy ,Cell Biology ,Hyperfunction ,Mitochondria ,Microscopy, Electron ,Metabolism ,Endocrinology ,chemistry ,RNA ,Rabbits ,Heart enlargement ,Electron microscope ,Adenosine triphosphate - Abstract
It has been shown with the method of electron microscopy that some days after the onset of the hyperfunction of the heart there arises in myocardial cells a significant augmentation of the mitochondrial mass along with a destruction of a part of the organelles. Later on after a considerable growth of the myocardial mass there occurs a normalization of the mass and structure of the mitochondria. In the latest stage of the process the destruction of mitochondria accompanied by a decrease of their mass is again observed. The obtained data are interpreted in the light of the concept of interrelation between the physiological function and the genetic apparatus of the differentiated cell.
- Published
- 1964