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The article focuses on a medical research that deals with the diagnosis of coronary heart disease in women under 65 at the time of a first myocardial infarction (MI) or diagnosis of angina without previous infarction. The incidences of coronary heart disease (CHD) among women are relatively low compared to men. Combined data from both the Ml and angina cohorts were used to examine the role of specified medical factors in prognosis. The patients from a specific group who received medical care for symptoms concerned with coronary disease were included in the study. It was deduced that early mortality after a first Ml was practically the same among women and men. The presence of hypertension and severe clinical episodes were associated with increased early mortality in women and in men.

In 182 hospitalized patients given fibrinolysin and anticoagulants, the rate of mortality following acute myocardial infarction was lower than the rate observed with anticoagulants alone. One million or more M.S.D. units of fibrinolysin was the most effective dose studied for maximum improvement in mortality rate. Side effects in the fibrinolysin-treated group were similar to those seen in the control group [ABSTRACT FROM AUTHOR]

A review has been presented of some of the more classical and recent findings in regard to results of anticoagulant therapy in acute myocardial infarction, the long-term prophylactic treatment of coronary artery disease, the use of anticoagulant therapy in cerebral vascular disease, as well as in postoperative thromboembolism. The most desirable procedures to be used for the control of oral anticoagulant therapy have been discussed as well as an evaluation as to which type of anticoagulant to use, i.e., heparin versus the oral anticoagulants. From this appraisal it appears that attention should be focused upon the evidence that anticoagulants effect morbidity more than they do mortality in most of the above mentioned conditions, as well as the fact that the role of heparin in anticoagulant therapy should be further evaluated on a clinical basis. [ABSTRACT FROM AUTHOR]

1. Many observations in acute myocardial infarction are difficult to explain and are similar to those made in experimental intravascular sludging. 2. Intravascular sludging is a consistent observation in acute myocardial infarction. 3. This sludging was treated in a well-established manner with low molecular dextran in an effort to determine if the sludging was a significant factor in the pattern of infarction and whether its control would be beneficial to the patient. 4. The results indicate that the sludging is undoubtedly a factor in the pattern of myocardial infarction. 5. Clinical observations and mortality figures are encouraging and do not contraindicate further study in this problem. Any further conclusions regarding benefits to the patients are unjustified in this preliminary stage. [ABSTRACT FROM AUTHOR]

Proposes an approach to measuring mortality rate of several chronic diseases. Types of mortality curvature; Mortality in cirrhosis of the liver; Mortality in disseminated breast cancer; Mortality in chronic lymphatic leukemia.

Focuses on the views of the clinical research teams on the effects of long-term anticoagulant therapy on patients suffering from acute myocardial infarction. Improvement on the quality of life; Reduction on the risks of complications; Decrease on the level of mortality rate.