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The article highlights on concept identification (CI) and psychophysiological parameters in depressed schizophrenics as functions of Imipramine and Nialamide. Depressed, male, chronic schizophrenics participated in a double-blind, placebo-controlled study of Imipramine and Nialamide. The subjects performed on CI tasks, that varied in complexity. Concomitant measures of electrodermal activity were obtained. The results of the study revealed that both antidepressants facilitated CI performance, and there was a negative relationship between CI errors and spontaneous GSRs.

A full drug history was taken from 378 patients admitted to a Psychiatric Service. Individuals who had received continuous psychotropic medication for 4 weeks were assessed for evidence of drug dependence as manifested by emotional distress on withdrawal or threat of withdrawal of the drug. 104 patients (27.5 per cent) were regarded as being drug dependent. Further characteristics of the patients and drugs are reviewed. [ABSTRACT FROM AUTHOR]