Search

Mayor Gamble has just spoken to you on water-supply from the standpoint of the health of citizens. May I discuss with you water from the standpoint of a chemist as it is required by industrial concerns as the most necessary feature of manufacturing operations, especially in the manufacture of pulp and paper, which promises to be the next great industrial development in this southeastern territory which is governed by your membership. A recent survey by the Federal Government has shown an enormous wealth of pine and semi-hardwood timber in this practically untouched region. The figures of this survey are now attracting nation-wide attention, especially since the spruce woods of the Great Lakes and Eastern States are practically exhausted and this makes necessary the importation annually of some two hundred million dollars worth of pulp and paper. About fifteen years ago when it was first proposed to manufacture kraft from southern pine it was loudly proclaimed that this was impossible, but during the intervening years there has been so rapid a growth of the kraft pulp and paper industries that the South now dominates the field with the manufacture of more than sixty percent of the national output. Now when it is proposed to use southern pine for white paper the same cry is heard about the unsuitability of southern pine. The work in the Pulp and Paper Laboratory of the Industrial Committee of Savannah has completely disproved this contention. Erroneous ideas have been held regarding our pines: first, through the use of the name "yellow" pine, which applies only to the heart, while the sapwood gives a pulp actually lighter in color than spruce; and, second, the utilization of longleaf and slash pines for naval stores

WATER is an integral part of the manufacture of pulp, paper, and paperboard. It plays a critical role in virtually every step of paper making, from the processing of pulp to the carrying of fibers to the paper-making machines. Water also is used to generate steam for power generation and for process use. Most of the water requirements are met by surface supplies (rivers and lakes) with the remainder from wells. Some mills also use city water. Since water-quality requirements for steam generation are well documented, this article will focus directly on process-water requirements and problems.

— The use of paper electrophoresis for the routine examination of urinary proteins in the dog has been studied. In the majority of dogs with nephritis the A/G ratios of the urinary proteins were found to be greater than those of corresponding sera and the electropherograms were fairly well defined. In a few cases the ratios were much smaller, and they were usually associated with high relative percentages of the β- and γ-fractions. Post-renal protein due to cystitis alone produced poorly defined electropherograms. These also resulted when both conditions were present. Urinary proteins with high relative percentages of β- and γ-globulins were also investigated and their electropherograms compared with those of γ-globulin preparations and with seminal plasma from male dog ejaculate. Urinary proteins from dogs suffering from a combination of diseases, e.g. nephritis and liver disorders, gave electropherograms that were not characteristic, although low A/G ratios appeared to be associated with prostatitis, with a case of splenic haematoma, and with some cases showing severe liver damage. It is concluded that paper electrophoresis of urinary proteins, particularly when performed on small “grab” samples has only limited use in routine clinical diagnosis. Resume— L'tlectrophorere au papier a ete employee pour I'etude des proteines dam l'urine du chien. Chez la majorite des chiens le rapport A/G dans l'albumine de l'urine a ete trouve augmente. Dans peu de cas, le rapport etait plus petit, quand le pourcentage Beta et Gamma etait plus eleve. L'albuminaire due a des cystites ne donnait que des electrophograms mediocres. Il en etait de meme quand une nephrite venait compliquer une cystite. Les proteines urinaires ayant une forte teneur de beta et de gamma globulines furent egalement etudiees, et leur electropherogramme compares au liquide seminal de chiens males. Les proteines urinaires de chiens souffrant simultanement de plusieurs maladies telles que nephrite et desordres hepatiques, donnerent des cliches peu caracteristiques, bien qu'un rapport A/G diminue semble etre associe a une prostatite, a un hematome splenique, et dam quelques cas de graves leions hepatiques. La conclusion est que l'electrophorese au papier, des proteines de l'urine, est d'un interet clinique limite, particulierement quand la quantite d'urine fournie est petite. Zusammenfassung— Die Anwendbarkeit der Papierelektrophorese zur Untersuchung der Harn-proteine des Hundes wurde studiert. Es konnte festgestellt werden, dass in der Mehrzahl der Hunde, die an Nephritis litten, die A/G Quotienten der Harnproteine hoher waren als der entsprechenden Sera und die erhalten Elektro-pherogramme waren ziemlich scharf definiert. In einigen wenigen Fallen waren die Quotienten betrachtlich kleiner und dann fand sich gewohnlich auch ein relativ hoher zugehoriger Anteil der Beta und Gamma Fraktion. Postrenales Protein, das lediglich durch Zystitis hervorgerufen war, zeigte verwaschene Elektrophorogramme. Solche Resultate wurden auch dann gesehen, wenn beide Erkrankungen zusammen vorlagen. Harnproteine mit einem relativ grossen Anteil von Beta und Gammaglobulin wurden ebenfalls untersucht und die erhaltenen Elektrophorogramme wurden mit solchen verglichen, die man rnit Gammaglobulin oder mit der Samenflussigkeit mannlicher Hunde erhielt. Hamproteine von Hunden, die an einer Kombination von verschiedenen Erkrankungen litten, 2.B. von Nephritis und Leberkrankheit, ergaben uncharakteristische Elektrophorogramme, es erschien jedoch, dass niedrige A/G Quotienten bei Prostatitis, bei einem Fall von Milzhaematom und bei einigen Fallen rnit schwerer Leberschadigung gefunden wurden. Es kann abschliessend gesagt werden, dass die Papierelektrophorese der Hamproteine, desonders wenn sie nur an gelegentlichen kleinen Proben ausgefuhrt wird, nur einen beschrankt klinisch diagnostischen Wert besitzt.

A RADIOIMMUNOASSAY FOR HUMAN PITUITARY LUTEINISING HORMONE USING PAPER CHROMATO-ELECTROPHORESIS

Summary The electrophoretic pattern of serum proteins has been studied in 30 infants suffering from toxicosis. During the stage of acute dehydration the main changes were a moderate or marked increase of alpha globulin, particularly of the α2 fraction and a decrease of albumin. In some cases there was also an increase of the gamma globulin. During recovery the alpha globulin decreases while albumin increases. However, the return to normal of the electrophoretic pattern is not always achieved when clinical recovery occurs. The absolute amounts of total serum proteins have also been estimated and their significance has been discussed. Electrophorese sur papier des proteines du serum au cours de la toxicose. L'aspect electrophoretique des proteines du serum a eteetudie chez 30 ehfants presentant une toxicose. Au cours de la periode de deshydratation aigue, on a pu noter une augmentation nette des alphaglobulines (en particulier la fraction alpha 2), et une diminution de l'albumine. Dans quelques cas, on a pu noter aussi une augmentation des gammaglobulines. La diminution des alphaglobulines, et l'augmentation de l'albumine est survenue avec la guerison. Neanmoins, le retour a la normale de la courbe d'electrophorese n'est pas toujours acheve au moment de la guerison elinique. Papierelektrophorese von Serum-Protein bei Sauglingstoxikose. Die Elektrophoresebefunde von Serumproteinen sind bei 30 an Toxikose leidenden Sauglingen untersucht worden. Wahrend des Stadiums der akuten Dehydration waren die Hauptveranderungen eine massige oder ausgepragte Zunahme des Alpha-Globulins, insbesondere der α2-Fraktion und eine Abnahme des Albumins. In einigen Fallen be-stand auch eine Zunahme des Gamma-Globulins. Wahrend der Genesung nimmt das Alpha-Globulin ab, wahrend das Albumin ansteigt. Jedoch ist der Ruckgang zum nor-malen elektrophoretischen Bild nicht immer vollendet wenn die klinische Genesung eintritt. Electroforesis en papel de las proteinas sericas en la toxicosis. Se estudiaron las imagenes electroforeticas de las proteinas sericas en 30 lactantes afectos de toxicosis. Durante el periodo de deshidratacion aguda, los cambios mas notables fueron un moderado o marcado aumento de la alfa globulina, especialmente de alfa 2. Durante la convalecencia, la fraecion alfa globulina disminuyo mientras au-mentaba la albumina. Sin embargo, la vuelta a la imagen electroforetica normal no siempre es completa al ocurrir, la mejoria clinica.

Summary In 21 premature infants, the birth weights of whom ranged between 1500 and 2400 g and the ages between 1 and 56 days, the total serum protein values have been determined and the serum protein components have been electrophoretieally differentiated. All infants were fed on human milk but, in 10 infants additional protein was administered (Casein preparation Secoosan). Total protein values were found to be lower in premature infants than in full-term infants. During the first eight weeks of life total protein values decreased, from 5.63 g per cent to 4.03 g per cent. The decrease in total protein is caused by a decrease in the amount of albumin (from a little below 3 g per cent in the first week of life to a little above 2 g per cent in the eighth week) and of gamma-globulin (from about 1 g per cent to about 0.5 g per cent) while the alpha1-, alpha2-and beta-globulin values remain rather constant. If casein is added to the diet the total serum protein values and the serum albumin values will range at higher levels, but the decrease with increasing age will not be prevented. On the contrary, additional casein to the diet will cause a further reduction in the gamma-globulin concentrations (Fig. 1). Taux des proteines dans le serum des prematures. Des determinations du taux des proteines totales ainsi que des taux particuliers des differentes proteines ont ete effectuees par electrophorese chez 21 bebes nes avant terme. Tous ces enfants etaient nourris au lait maternel et 10 d'entre eux recurent des supplements de proteines. Il est apparu que le taux des proteines totales etait plus faible chez les prematures que chez les enfants nes a terme. Au cours des huit premieres semaines qui suivirent la naissance, le taux des proteines totales descendit de 5,63 g%a 4,03 g%. Cet abaissenient du taux des proteines totales provenait de la diminution de la concentration en alburnine (qui d'abord legerement inferieure a 3 g % au cours de la premiere semaine etait descendue a un niveau legerement superieur a 2 g % au bout de huit semaines) et en gamma-globuline (qui, etant d'environ 1 g %etait descendue a environ 0,5 g %), tandis que les taux des globulines alpha1, alpha2 et beta etaient restes relativement constants. L'addition de caseine a la nourriture fit monter les taux des proteines totales et de l'albumine a des niveaux plus eleves, mais ces concentrations diminuerent egalement avec le temps. D'autre part, l'addition de caseine a la nourriture entraina une diminution plus importante du taux des gamma-globulines. Serumproteinwerte bei fruhgeborenen Kmdern. Bei 21 fruhgeborenen Kindern wurden die gesamten Serumproteinwerte bestimmt und die Serumproteinbestandteile elektrophoretisch differenziert. Alle Kinder wurden nut Frauenmilch ernahrt, aber 10 Kinder erhielten einen Eiweisszusatz. Die gesamten Proteinwerte erwiesen sich bei den fruhgeborenen Kindern als niedriger als in vollreif geborenen. Wahrend der ersten 8 Lebenswochen fielen die totalen Proteinwerte von 5,63 % auf 4,03 % ab. Der Fall im Gesamtproteingehalt ist durch einen Abfall im Albumingehalt bedingt (von ein wenig unter 3 g % in der ersten Lebenswoche auf ein wenig uber 2 g % in der achten Woche) und Gammaglobulingehalt (von ca. 1 g % auf ca. 0,5 g%), wahrend die Alpha1-, Alpha2-und Betaglobulinwerte ziemlich konstant bleiben. Wenn Kasein zur Diat zugefugt wird, werd. en die gesamten Serumproteinund Serumalbuminwerte ein hoheres Niveau erreichen, aber der mit dem Alter einhergehende Abfall wird nicht verhindert werden. Im Gegenteil, der Kaseinzusatz zur Diat bewirkt eine weitere Herabsetzung der Gammaglobulinkonzentrationen. Valores seroproteicos en los prematuros. Han sido determinados, en 21 prematures, los valores seroproteicos totales y diferenciados electroforeticamente los componentes seroproteicos. Todos los ninos fueron alimentados con leche humana, pero a 10 de ellos se les administraron proteinas adicionales. Hallose que los valores proteicos totales eran inferiores en los prematuros a los de los ninos nacidos a termino. Durante las ocho primeras semanas de la vida, los valores proteicos totales disminuyeron. de 5.63 g % a 4.03 g %. La disminucion del total proteico esta causada por una disminueion de la cantidad de albumina (desde un poco menos de 3 g % en la primera semana de la vida hasta un poco mas de 2 g % en la octava semana) y de gammaglobulina (desde aproximadamente 1 g % a aproximadarnente 0.5 g %) mientras los valores globulinicos alfa1, alfa2 y beta, permanecen bastante constantes. Si se anade caseina a la dieta, los valores seroproteicos totales y los valores seroalbuminosos alcanzaran niveles mas elevados, pero la disminueion, al aumentar la edad, no podra evitarse. La caseina, contraria, adioionada a la dieta, causara todavia mas reduccion en las concentraciones gammaglobulinicas.

Seven types of materials used for storage of produce (maize, groundnuts, etc.) were tested for penetration by nine species of insects which infest such produce. The relative values of the materials for preventing damage to the produce are determined and recommendations made as to suitable materials in certain cases and the procedure which should be followed in the storage of produce.

The efficient production of “Geophysical Prospecting” depends upon the co-operation of the individual authors and this paper serves as a guide for them. Some suggestions are also made on the presentation of papers at meetings in the hope of promoting successful discussions.

Two steers excreting similar quantities of organic matter daily were grazed at pasture during the summer of 1961. The four experiments each involved a preliminary period of five days dosing with Cr2O3 to reach a fairly constant excretion. The steers received a daily dose of Cr2O3 either in oil suspension or in shredded paper. The carriers and steers were interchanged for each trial. For two of the trials each steer in turn was harnessed every other day and all its dung collected in a bag. Total faecal excretion of organic matter was measured from the bagged steer and estimated from the Cr2O3 concentration in a composite sample made up from all dung pats voided during the ten-day collection period. In the other two trials the steers were not harnessed and each dung pat was separately sampled and analysed for Cr2O3 in the organic matter. The average recovery of Cr2O3 in the first two trials was 99·1 (oil) or 94·4% (paper). Calculating the faecal organic matter excretion from the concentration of Cr2O3 in the faeces and the quantity given daily overestimated it by 3·5 to 8·0%. There was no significant difference between shredded paper and oil as carriers of Cr2O3 for estimating the quantity of organic matter excreted. There were 37% and 22% less variation between dung pats in Cr2O3 concentration when this was administered in shredded paper than when given in oil suspension.

Author's Note: There seem to he some points which are not clear and some omissions which have caused confusion in the paper1 presented by the writer. Owing to the length of this paper, some data were purposely omitted for the sake of brevity. The writer wishes to thank Professor Lord for bringing these points to his attention and also for permitting this discussion of the preceding paper.

A few of the areas of paper making where automation has had a significant impact are reviewed, viz. in stock proportioning, consistency control, control of the drying of paper, continuous colouring of paper, basis-weight control, and the problem of trim. On-line computer control of the paper-making machine is briefly discussed.

This paper is de(licate(l to mn life-long friend and colleague, Doctor Henry Chandler Cowles, whose thought and enthusiasm have exerted such notable influence in the rapid (levelol)ment of American ecology throughout a third of a century. His remarkable paper on sandl-(lune vegetation and his early al)l)reciation of the dynamic relations of plant distril)ution to physiographic development came as enlightening encouragement to those who had dreamedd that it might sometime be possible to approach problems of plant distribution from the physiological viewpoint. Studies like those of Cowles furnished a logical method by which the environmental complexes of plant habitats might be usefully characterized and classified according to soils and exposure, inl terms of physiographic features that naturally pass through progressive changes with the lapse of years and centuries. Such simply descriptive terms as moraine, bluff, talus, bajada, beach, strand, lagoon, swamp, thus came to imply slowly changing systems of environmental conditions. Of course the need for a still more penetrating examination of environmental complexes was realized. It was desirable that habitat features should be described in such terms as might replresent conditions to which the indiviclual plant is sensitive, which is not immediately true of geographic or physiographic concepts; at the same time, the terms of habitat description should be susceptible of physical and chleical measurement and integration whenever suitable techniques therefor might be developed. Accordingly, there has arisen a special branch of ecology, which has been called physiological ecology. Considerable progress in physiological ecology had been made by agricultural chemists before ecology took its place among the biological sciences, and their studies on the soil relations of cultivated plants constituted an important part of the fundamental basis for the new science, although it is still sometimes forgotten that ecology must logically include cultivated forms and weeds in its purview, as well as the components of natural plant associations and other natural vegetational units. Agronomy and horticulture furnish the most readily approachable fields for fundamental ecological research, and workers in these fields early turned their attention to soil characteristics as effective environmental features. It was soon realized that the soil condi

This paper describes the development and application of an algorithm which generates non-linear representations of English text. The algorithm uses the results of a syntactic analysis system and a set of rules which prescribe linkages to generate a graph of a sentence. The shape of these graphs corresponds to the syntax of the sentence; the labels correspond to the vocabulary of the sentence and the edge types correspond to case grammar roles. The sentence graphs can then be interconnected at common nodes and analyzed according to common edges. Preliminary experimentation has yielded promising results. It appears that the algorithm produces a representation of English text which could be quite useful in automatic language processing.

Summary To conclude this paper, the most important points may be summarized as follows. Firstly, pollution by dairy effluents will have to be stopped, not only for reasons of good public relations, but also because of impending trouble for future offenders when recent legislation begins to take effect. Secondly, the best and cheapest way of reducing the size of the problem is to reduce losses in the dairy of milk solids of all sorts, especially by-products of low cash value but high polluting power. Thirdly, direct disposal of the remaining effluent is always best, where possible, but the only method of doing this which can be unreservedly recommended is by a pipe-line to the sea or to the sewer of a willing Local Authority. Direct disposal on land may be a tempting method financially, but is only satisfactory in exceptional places, and is always a potential source of complaints from neighbours. Fourthly, for most dairies some kind of effluent purification treatment is unavoidable. At small non-manufacturing dairies, where sludge disposal is not too difficult, the chemical precipitation process followed by irrigation has the advantage of simplicity and low capital cost. If space is limited, single biological filtration can be used for the final stage instead of irrigation. Scarlett's process of aerobic fermentation followed by biological filtration seems more suitable for larger dairies. The activated sludge process is relatively compact and cheap, but is unsuitable for manufacturing dairies with fluctuating load. Of the various biological filtration systems, in our experience the method of choice, when the load is heavy and where a high quality effluent is essential, is undoubtedly the double-alternating system. It is unfortunately also very expensive. The cost of filter beds, which is the largest item, can be reduced by using one of the high-rate systems, but these usually involve a bigger sludge disposal problem and an inferior effluent. Finally, I would like to repeat a plea often made before. An effluent plant should be regarded as part of the normal dairy equipment, and should be cared for like the rest of the factory. It should not be thought of as a mere nuisance, or something to be fitted and forgotten. In our experience, the effluent plant that is best looked after gives the least trouble and the best results. This is not achieved by putting it in charge of the most incompetent odd-job man in the factory, who is thought fit for nothing better than sewage.

This I write not to contradict but to support, to the best of my power, the idea for which the author tries to make propaganda. I have myself done something of that kind already in 1911 by my article «Eine Methode, die Nabelabklemmung mit der Unterbindung zu kombinieren« appearing in Zentralbl. f. Gynak. 35. Jahrg. No. 31. — I have besides published papers on this subject in medical journals of my own country and already in those days I was far from the first one who dealt with the said topic.

An improved method for the liquid scintillation counting of 14C-phytoplankton material on membrane filter papers is described. The method involves the incorporation of standard 14C-sucrose into the filter, and it clearly demonstrates that the counting efficiency of the sample is affected by the amount of material present. It is concluded that the cells and the membrane filter have a self-absorptive effect that previous methods of counting, using internal and external standardization, cannot have fully detected.

The Budget of the United States Government for FY 1975 clearly shows that the shapers of public opinion and the makers of public policy do not understand what we are about and what we do. In FY 1975, the National Science Foundation's program and facilities obligations will be close to $600,000,000. Estimated obligations for FY 1974 are $569,000,000. This is an increase of nearly $30,000,000. The accompanying narrative states that this increase “reflects the administration's support for fundamental knowledge necessary for economic growth and long-range solutions of problems of national concern.” The OSIS estimated obligations for the same period are $8,000,000 in FY 1974 and $5,000,000 in FY 1975. Even the Office of Management and Budget would not have made a 40% cut from the OSIS FY 1974 budget if it had understood the importance of information science, or if it had felt that a cohesive, vocal and strong profession with some congressional friends might be heard from. The following is the statement submitted by Joshua I. Smith on behalf of ASIS to the Subcommittee on Science Research and Development of the Committee on Science and Astronautics of the U.S. House of Representatives on the National Science Foundation Authorization Act 1975, H.R. 12816, regarding science information systems, 19 March 1974.